Histochemistry and cytochemistry of nuclear receptors

Progress in Histochemistry and Cytochemistry

Volumn 36, Issue 2, 2001, Pages 91-176

  Yamashita, Shuji ^a  

^a Keio Junior College of Nursing   (Japan)

Author keywords

Autoradiography; Carcinogenesis (hormone dependent independent); Histochemical methodologies; Immunohistochemistry; In situ hybridization; Mesenchymal; Nuclear receptor family; Nuclear transcription factors; Receptor mRNAs; Stromal interaction

Indexed keywords

ANDROGEN RECEPTOR; CELL RECEPTOR; ESTROGEN RECEPTOR; GLUCOCORTICOID RECEPTOR; GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; PROGESTERONE RECEPTOR; STEROID RECEPTOR;

ANIMAL; CYTOCHEMISTRY; FEMALE; HUMAN; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; MALE; PHYSIOLOGY; REVIEW;

ANIMALS; FEMALE; GREEN FLUORESCENT PROTEINS; HISTOCYTOCHEMISTRY; HUMANS; IMMUNOHISTOCHEMISTRY; LUMINESCENT PROTEINS; MALE; MICROSCOPY, IMMUNOELECTRON; RECEPTORS, ANDROGEN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, ESTROGEN; RECEPTORS, GLUCOCORTICOID; RECEPTORS, PROGESTERONE; RECEPTORS, STEROID;

EID: 0035229446     PISSN: 00796336     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0079-6336(01)80004-8     Document Type: Article

References (277)

1. AGARWAL, V. R., SINTON, C. M., LIANG, C., FISHER, C., GERMAN, D. C., SIMPSON, E. R.: Upregulation of estrogen receptors in the forebrain of aromatase knockout (ArKO) mice. - Mol. cell. Endocrinol. 162, 9-16 (2000).
2. AKNER, G., MOSSBERG, K., WIKSTROM, A. C, SUNDQVIST, K. G., GUSTAFSSON, J. A.: Evidence for colocalization of glucocorticoid receptor with cytoplasmic microtubules in human gingival fibroblasts using two different monoclonal anti-GR antibodies, confocal laser scanning microscopy and image analysis. - J. Steroid. Biochem. molec. Biol. 39, 419-432 (1991).
3. ALEXANDER, R. B., GREENE, G. L., BARRACK, E. R.: Estrogen receptors in the nuclear matrix: Direct demonstration using monoclonal antireceptor antibody. - Endocrinology 120, 1851-1857 (1987).
4. ALVES, S. E., LOPEZ, V., MCEWEN, B. S., WEILAND, N. G.: Differential colocalization of estrogen receptor β (ERβ) with oxytocin and vasopressin in the paraventricular and supraoptic nuclei of the female rat brain: an immunocytochemical study. - Proc. natl. Acad. Sci. USA 95, 3281-3286 (1998).
5. 3 receptor in osteoblast. - Arch. Histol. Cytol. 55, 77-88 (1992).
6. ANTAKLY, T., RAQUIDAN, D., O'DONNELL, D., KATNICK, L.: Regulation of glucocorticoid receptor expression: I. Use of a specific radioimmunoassay and antiserum to a synthetic peptide of - the N-terminal domain. - Endocrinology 126, 1821-1828 (1990).
7. ARAI, Y., MORI, T., SUZUKI, Y., BERN, H. A.: Long-term effect of perinatal exposure to sex steroids and diethylstilbestrol on the reproductive systems of male mammals. - Int. Rev. Cytol. 84, 235-268 (1983).
8. ARONSSON, M., FUXE, K., DONG, Y., AGNATI, L. F., OKRET, S., GUSTAFSSON, J. A.: Localization of glucocorticoid receptor mRNA in the male rat brain by in situ hybridization. - Proc. natl. Acad. Sci. USA 85, 9331-9335 (1988).
9. BARRACK, E. R.: The nuclear matrix of the prostate contains acceptor sites for androgen receptors. - Endocrinology 113, 430-432 (1983).
10. BARRACK, E. R., COFFEY, D. S.: Biological properties of the nuclear matrix: Steroid hormone binding. - Recent Prog. Horm. Res. 38, 133-195 (1982).
11. BAUER, U. M., SCHNEIDER-HIRSCH, S., REINHARDT, S., BENAVENTE, R., MAELICKE, A.: The murine nuclear orphan receptor GCNF is expressed in the XY body of primary spermatocytes. - FEBS Lett. 439, 208-214 (1998).
12. BEATO, M., SANCHEZ-PACHECO, A.: Interaction of steroid hormone receptors with the transcription initiation complex. - Endocr. Rev. 17, 587-609 (1996).
13. BENTVELSEN, F. M., BRINKMANN, A. O., VAN DER SCHOOT, P., VAN DER LINDEN, J. E., VAN DER KWAST, T. H., BOERSMA, W. J., SCHRODER, F. H., NIJMAN, J. M.: Developmental pattern and regulation by androgens of androgen receptor expression in the urogenital tract of the rat. - Mol. cell. Endocrinol. 113, 245-253 (1995).
14. BERBERS, G. A., KUNNEN, R., VAN BERGEN EN HENEGOUWEN, P. M., VAN WIJK, R.: Localization and quantitation of hsp84 in mammalian cells. - Exp. Cell Res. 177, 257-271 (1988).
15. BERGER, U., WILSON, P., MCCLELLAND, R. A., COLSTON, K., HAUSSLER, M. R., PIKE, J. W.: Immunocytochemical detection of 1,25-dihydroxyvitamin D receptors in normal human tissues. - J. clin. Endocrinol. Metab. 67, 607-613 (1988).
16. BERGERON, C., FERENCZY, A., TOFT, D. O., SCHNEIDER, W., SHYAMALA, G.: Immunocytochemical study of progesterone receptors in the human endometrium during the menstrual cycle. - Lab. Invest. 59, 862-869 (1988).
17. Bern, H.A., Edery, M., Mills, K. T., Kohrman, A. E., Mori, T., Larson, L.: Long-term alterations in histology and steroid receptor levels of the genital tract and mammary gland following neonatal exposure of female BALB/cCrgl mice to various doses of diethylstilbestrol. - Cancer Res. 47, 4165-4172 (1987).
18. BERN, H. A., JONES, L. A., MORI, T., YOUNG, P. N.: Exposure of neonatal mice to steroids: long-term effects on the mammary gland and other reproductive structures. - J. Steroid. Biochem. 6, 673-676 (1975).
19. BIGSBY, R. M., AIXIN, L., LUO, K., CUNHA, G. R.: Strain differences in the ontogeny of estrogen receptors in murine uterine epithelium. - Endocrinology 126, 2592-2596 (1990).
20. BIGSBY, R. M., CUNHA, G. R.: Estrogen stimulation of deoxyribonucleic acid synthesis in uterine epithelial cells which lack estrogen receptors. - Endocrinology 119, 390-396 (1986).
21. BIGSBY, R. M., LI, A.: Differentially regulated immediate early genes in the rat uterus. - Endocrinology 134, 1820-1826 (1994).
22. BRAISSANT, O., FOUFELLE, F., SCOTTO, C., DAUCA, M., WAHLI, W.: Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-α, -β, and -γ in the adult rat. - Endocrinology 137, 354-366 (1996).
23. BRINK, M., HUMBEL, B. M., H., KLOET, E. R., DRIEL, R. V.: The unligand glucocorticoid receptor is localized in the nucleus, not in the cytoplasm. - Endocrinology 130, 3575-3581 (1992).
24. BROCK, M. L., SHAPIRO, D. J.: Estrogen stabilizes vitellogenin mRNA against cytoplasmic degradation. - Cell 34, 207-214 (1983).
25. BUCHANAN, D. E., KURITA, T., TAYLOR, J. A., LUBAHN, D. B., CUNHA, G. R., COOKE, P. S.: Role of stromal and epithelial estrogen receptors in vaginal epithelial proliferation, stratification, and cornification. - Endocrinology 139, 4345-4352 (1998).
26. BUCHANAN, D. E., SETIAWAN, T., LUBAHN, D. B., TAYLOR, J. A., KURITA, T., CUNHA, G. R., COOKE, P. S.: Tissue compartment-specific estrogen receptor-α participation in the mouse uterine epithelial secretory response. - Endocrinology 140, 484-491 (1999).
27. BYERS, M., KUIPER, G. G. J. M., GUSTAFSSON, J. A., PARK-SARGE, O. O. K.: Estrogen receptor-β mRNA expression in rat ovary: down-regulation by gonadotropins. - Mol. Endocrinol. 11, 172-182 (1997).
28. CERILLO, G., REES A., MANCHANDA, N., REILLY, C., BROGAN, I., WHITE, A., NEEDHAM, M.: The oestrogen receptor regulates NFκB and AP-1 activity in a cell-specific manner. - J. Steroid. Biochem. mol. Biol. 67, 79-88 (1998).
29. CHANDRAN, U. R., DEFRANCO, D. B.: Internuclear migration of chicken progesterone receptor, but not simian virus-40 large tumor antigen, in transient heterokaryons. - Mol. Endocrinol. 6, 837-844 (1992).
30. CHEN, E, COONEY, A. J., WANG, Y., LAW, S. W., O'MALLEY, B. W.: Cloning of a novel orphan receptor (GCNF) expressed during germ cell development. - Mol. Endocrinol. 8, 1434-1444 (1994).
31. CHINETTI, G., GRIGLIO, S., ANTONUCCI, M., TORRA, I. P., DELERIVE, P., MAJD, Z., FRUCHART, J. C., CHAPMAN, J., NAJIB, J., STAELS B.: Activation of proliferator-activated receptors α and γ induces apoptosis of human monocyte-derived macrophages. - J. biol. Chem. 273, 25 573-25 580 (1998).
32. CIDLOWSKI, J. A., BELLINGHAM, D. E., POWELL-OLIVER, F. E., LUBAHN, D. B., SAR, M.: Nobel antipeptide antibodies to the human glucocorticoid receptor: recognition of multiple receptor forms in vito and distinct localization of cytoplasmic and nuclear receptors. - Mol. Endocrinol. 4, 1427-1437 (1990).
33. CIEJEK, E. M., TSAI, M. J., O'MALLEY, B. W.: Actively transcribed genes are associated with the nuclear matrix. - Nature 306, 607-609 (1983).
34. 3 receptor in target cells. - Endocrinology 122, 1224-1230 (1988).
35. COOKE, P. S., BUCHANAN, D. L., YOUNG, P., SETIAWAN, T., BRODY, J., KORACH, K. S., TAYLOR, J., LUBAHN, D. B., CUNHA, G. R.: Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium. - Proc. natl. Acad. Sci. USA 94, 6535-6540 (1997).
36. COOKE, P. S., YOUNG, P., CUNHA, G. R.: Androgen receptor expression in developing male reproductive organs. - Endocrinology 128, 2867-2873 (1991a).
37. Cooke, P. S., Young, P., Hess, R. A., Cunha, G. R.: Estrogen receptor expression in developing epididymis, efferent ductules, and other male reproductive organs. - Endocrinology 128, 2874-2879 (1991b).
38. COUSE, J. F., LINDZEY, J., GRANDIEN, K., GUSTAFSSON, J. A., KORACH, K. S.: Tissue distribution and quantitative analysis of estrogen receptor-α (ERα) and estrogen receptor-β (ERβ) messenger ribonucleic acid in the wild-type and ERα-knockout mouse. - Endocrinology 138, 4613-4621 (1997).
39. CUNHA, G. R., CHUNG, L. W. K., SHANNON, J. M., TAGUCHI, O., FUJII, H.: Hormone-induced morphogenesis and growth: Role of mesenchymal-epithelial interaction. - Rec. Prog. Hormone Res. 39, 559-598 (1983).
40. CUNHA, G. R., LUNG, B.: The possible influence of temporal factors in androgenic responsiveness of urogenital tissue recombinants from wild-type and androgen-insensitive (Tfm) mice. - J. exp. Zool. 205, 181-194 (1978).
41. CURTIS, S. W., WASHBURN, T., SEWALL, C., DIAUGUSTINE, R., LINDZEY, J., COUSE, J. F., KORACH, K. S.: Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor. - Proc. natl. Acad. Sci. USA 93, 12626-12630 (1996).
42. DIAUGASTIN, R. P., PETRUSE, P., BELL, G. I., BROWN, C. F., KORACH, K. S., MCLACHLAN, J. A., TENG, C. T.: Influence of estrogens on mouse uterine epidermal growth factor precursor protein and messenger ribonucleic acid. - Endocrinology 122, 2355-2363 (1988).
43. Dolle, P., Fraulob, V., Kastner, P., Chambon, P.: Developmental expression of murine retinoid X receptor (RXR) genes. - Mech. Dev. 45, 91-104 (1994).
44. DOLLE, P., RUBERTE, E., LEROY, P., MORRISS-KAY, G., CHAMBON, P.: Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. - Development 110, 1133-1151 (1990).
45. DUNCAN, S. A., MANOVA K., CHEN, W. S., HOODLESS, P., WEINSTEIN, D. C., BACHVAROVA, R. F., DARNELL, J. E. Jr.: Expression of transcription factor HNF-4 in the extraembryonic endoderm, gut, and nephrogenic tissue of the developing mouse embryo: HNF-4 is a marker for primary endoderm in the implanting blastocyst. - Proc. natl. Acad. Sci. USA 91, 7598-7602 (1994).
46. ERCAN-FANG, S., SCHWARTZ, H. L., OPPENHEIMER, J. H.: Isoform-specific 3,5,3′-triiodothyronine receptor binding capacity and messenger ribonucleic acid content in rat adenohypophysis: effect of thyroidal state and comparison with extrapituitary tissues. - Endocrinology 137, 3228-3233 (1996).
47. EVANS, R. M.: The steroid and thyroid hormone receptor superfamily. - Science 240, 889-895 (1988).
48. FALCONE, M., MIYAMOTO, T, FIERRO-RENOY, F., MACCHIA, E., DEGROOT, L. J.: Antipeptide polyclonal antibodies specifically recognize each human thyroid hormone receptor isoform. - Endocrinology 131, 2419-2429 (1992).
49. FEJES-TOTH, G., PEARCE, D., NARAY-FEJES-TOTH, A.: Subcellular localization of mineralocorticoid receptors in living cells: effects of receptor agonists and antagonists. - Proc. natl. Acad. Sci. USA 95, 2973-2978 (1998).
50. FORMAN, B. M., GOODE, E., CHEN, F., ORO, A. E., BRADLEY, D. J., PERLMANN, T., NOONAN, D. J., BURKA, L. T., MCMORRIS, T., LAMPH, W. W., EVANS, R. M., WEINBERGER, C.: Identification of a nuclear receptor that is activated by farnesol metabolites. - Cell 81, 687-693 (1995).
51. Forsberg, J.-G.: Developmental mechanism of estrogen-induced irreversible changes in the mouse cervicovaginal epithelium. - Natl. Cancer Inst. Monogr. 51, 41-56 (1977).
52. GARZA, R., PUYMIRAT, J., DUSSAULT, J. H.: Immunocytochemical localization of thyroid hormone nuclear receptors in cultured acetylcholinesterase-positive neurons: a correlation between the presence of thyroid hormone nuclear receptors and L-tri-iodothyronine morphological effects. - Neuroscience 36, 473-482 (1990).
53. GASC, J. M., DELAHAYE, F., BAULIEU, E.-E.: Compared intracellular localization of glucocorticoid and progesterone receptors: An immunohistochemical study. - Exp. Cell Res. 181, 492-504 (1989).
54. GASC, J. M., RENOIR, J. M., RADANYI, C., JOA, I., TUOHIMAA, P., BAULIEU, E. E: Progesterone receptor in the chick oviduct: an immunohistochemical study with antibodies to distinct receptor components. - J. Cell Biol. 99, 1193-1201 (1984).
55. GAUB, M. P., BELLARD, M., SCHEUER, I., CHAMBON, P., SASSONE-GORSI, P.: Activation of ovalbumin gene by estrogen receptor involves the Fos-Jun complex. - Cell 63, 1267-1276 (1990).
56. GEORGET, V., LOBACCARO, J. M., TEROUANNE, B., MANGEAT, P., NICOLAS, J. C., SULTAN, C.: Trafficking of the androgen receptor in living cells with fused green fluorescent protein-androgen receptor. - Mol. cell. Endocrinol. 129, 17-26 (1997).
57. GERDES, M. J., DANG, T. D., LARSEN, M., ROWLEY, D. R.: Transforming growth factor-β1 induces nuclear to cytoplasmic distribution of androgen receptor and inhibits androgen response in prostate smooth muscle cells. - Endocrinology 139, 3569-3577 (1998).
58. GIGUERE, V.: Orphan nuclear receptors: from gene to function. - Endocr. Rev. 20, 689-725 (1999).
59. GIGUERE, V., ONG, E., SEGUI, P., EVANS, R. M.: Identification of a receptor for the morphogen retinoic acid. - Nature 330, 624-629 (1987).
60. Gittoes, N.J., McCabe, C. J., Verhaeg, J., Sheppard, M. C., Franklyn, J. A.: An abnormality of thyroid hormone receptor expression may explain abnormal thyrotropin production in thyrotropin-secreting pituitary tumors. - Thyroid 8, 9-14 (1998).
61. GORLICH, D., MATTAJ, I. W.: Nucleocytoplasmic transport. - Science 271, 1513-1518 (1996).
62. GORSKI, J., TOFT, D., SHYAMALA, G., SMITH, D., NOTIDES, A.: Hormone receptors. Studies on the interaction of estrogen with the uterus. - Rec. Prog. Hormone Res. 24, 45-80 (1968).
63. GRAHAM, J. D., YEATES, C., BALLEINE, R. L., HARVEY, S. S., MILLIKEN, J. S., BILOUS, A. M., CLARKE, C. L.: Progesterone receptor A and B protein expression in human breast cancer. - J. Steroid. Biochem. molec. Biol. 56, 93-98 (1996).
64. GRECO, T. L., DUELLO, T. M., GORSKI, J.: Estrogen receptors, estradiol, and diethylstilbestrol in early development: the mouse as a model for the study of estrogen receptors and estrogen sensitivity in embryonic development of male and female reproductive tracts. - Endocr. Rev. 14, 59-71 (1993).
65. GUIOCHON-MANTEL, A., DELABRE, K., LESCOP, P., MILGROM, E.: Intracellular traffic of steroid hormone receptors. - J. Steroid Biochem. molec. Biol. 56, 3-9 (1996).
66. -: Nuclear localization signals also mediate the outward movement of proteins from the nucleus. - Proc. natl. Acad. Sci. USA 91, 7179-83 (1994).
67. GUIOCHON-MANTEL, A., LESCOP, P., CHRISTIN-MAITRE, S., LOOSFELT, H., PERROT-APPLANAT, M., MILGROM, E.: Nucleocytoplasmic shuttling of progesterone receptor. - EMBO J. 10, 3851-5859 (1991).
68. HACHE, R. J., TSE, R., REICH, T., SAVORY, J. G., LEFEBVRE, Y. A.: Nucleocytoplasmic trafficking of steroid-free glucocorticoid receptor. -J. biol. Chem. 274, 1432-1439 (1999).
69. HAMILTON, B. A., FRANKEL, W. N., KERREBROCK, A. W., HAWKINS, T. L., FITZHUGH, W., KUSUMI, K., RUSSELL, L. B., MUELLER, K. L., VAN BERKEL, V., BIRREN, B. W., KRUGLYAK, L., LANDER, E. S.: Disruption of the nuclear hormone receptor RORα in staggerer mice. - Nature 379, 736-739 (1996).
70. HATANO, O., TAKAYAMA, K., IMAI, T., WATERMAN, M. R., TAKAKUSU, A., OMURA, T., MOROHASHI, K.: Sex-dependent expression of a transcription factor, Ad4BP, regulating steroidogenic P-450 genes in the gonads during prenatal and postnatal rat development. - Development 120, 2787-2797 (1994).
71. HE, Y. W., DEFTOS, M. L., OJALA, E. W., BEVAN, M. J.: RORγt, a novel isoform of an orphan receptor, negatively regulates Fas ligand expression and IL-2 production in T cells. - Immunity 9, 797-806 (1998).
72. HERBST, A. L., ULFELDER, H., POSKANZER, D. C.: Adenocarcinoma of the vagina: association of maternal stilbestrol therapy with tumor appearance in young women. - N. Engl. J. Med. 284, 878-881 (1971).
73. HERTZ, R., MAGENHEIM, J., BERMAN, I., BAR-TANA, J.: Fatty acyl-CoA thioesters are ligands of hepatic nuclear factor-4α. - Nature 392, 512-516 (1998).
74. HIROI, H., INOUE, S., WATANABE, T., GOTO, W., ORIMO, A., MOMOEDA, M., TSUTSUMI, O., TAKETANI, Y., MURAMATSU, M.: Differential immunolocalization of estrogen receptor α and β in rat ovary and uterus. - J. mol. Endocrinol. 22, 37-44 (1999).
75. HOLLEY, S. J., YAMAMOTO, K. R.: A role for Hsp90 in retinoid receptor signal transduction. - Mol. Biol. Cell 6, 1833-1842 (1995).
76. HOLLENBERG, S. M., WEINBERGER, C., ONG, E. S., CERELLI, G., ORO, A., LEBO, R., THOMPSON, E. B., ROSENFELD, M. G., EVANS, R. M.: Primary structure and expression of a functional hu-man glucocorticoid receptor cDNA. - Nature 318, 635-641 (1985).
77. HONDA, S., MOROHASHI, K., NOMURA, M., TAKEYA, H., KITAJIMA, M., OMURA, T.: Ad4BP regulating steroidogenic P-450 gene is a member of steroid hormone receptor superfamily. - J. biol. Chem. 268, 7494-7502 (1993).
78. HSIEH, J. C., SHIMIZU, Y, MINOSHIMA, S., SHIMIZU, N., HAUSSLER, C. A., JURUTKA, P. W, HAUSSLER, M. R.: Novel nuclear localization signal between the two DNA-binding zinc fingers in the human vitamin D receptor. - J. cell. Biochem. 70, 94-109 (1998).
79. Hsu, S., QI, M., FEFRANCO, D. B.: Cell cycle regulation of glucocorticoid receptor function. EMBO - J. 11, 3457-3468 (1992).
80. HTUN, H., BARSONY, J., RENYI, L, GOULD, D. L., HAGER, G. L.: Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera. - Proc. natl. Acad. Sci. USA 93, 4845-4850 (1996).
81. HTUN, H., HOLTH, L. T., WALKER, D., DAVIE, J. R., HAGER, G. L.: Direct visualization of the human estrogen receptor α reveals a role for ligand in the nuclear distribution of the receptor. - Mol. Biol. Cell. 10, 471-486 (1999).
82. HUSMANN, D.S., WILSON, C.M., MCPHAUL, M. J., TILLEY, W. D., WILSON, J. D.: Antipeptide antibodies to two distinct regions of the androgen receptor localize the receptor protein to the nuclei of target cells in the rat and human prostate. - Endocrinology 126, 2359-2368 (1990).
83. Ignar-Trowbridge, D. M, Nelson, K. G., Bidwell, M. C., Curtis, S. W., Washburn, T. W., McLachlan, J. A., Korach, K. S.: Coupling of dual signaling pathways: Epidermal growth factor action involves the estrogen receptor. - Proc. natl. Acad. Sci. USA 89, 4658-4662 (1992).
84. IGUCHI T.: Cellular effects of early exposure to sex hormones and antihormones. - Int. Rev. Cytol. 139, 1-57 (1992).
85. IGUCHI, T., EDERY, M., TSAI, P. S., OZAWA, S., SATO, T., BERN, H. A.: Epidermal growth factor receptor levels in reproductive organs of female mice exposed neonatally to diethylstilbestrol. - Proc. Soc. exp. Biol. Med. 204, 110-116 (1993).
86. IKEDA, Y, LALA, D. S., LUO, X., KIM, E., MOISAN, M. P., PARKER, K. L.: Characterization of the mouse FTZ-F1 gene, which encodes a key regulator of steroid hydroxylase gene expression. - Mol. Endocrinol. 7, 852-860 (1993).
87. IKEDA, Y., SHEN, W. H., INGRAHAM, H. A., PARKER, K. L.: Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. - Mol. Endocrinol. 8, 654-662 (1994).
88. ISOLA, J., PELTO-HUIKKO, M., YLIKOMI, T., TUOHIMAA, P.: Immunoelectron microscopical localization of progesterone receptor in the chick oviduct. - J. Steroid Biochem. 26, 19-23 (1987).
89. ISOLA, J., YLIKOMI, T., TUOHIMAA, P.: Nuclear origin of progesterone receptor of the chick oviduct cytosol. An immunoelectron microscopic study. - Histochemistry 86, 53-58 (1986).
90. ITO, H., TOYOSHIMA, I., MIZUNUMA, H., KOBAYASHI, R., TASHIMA, Y.: Three-step purification method and characterization of the bovine brain 90-kDa heat shock protein. - Arch. Biochem. Biophys. 252, 290-296 (1990).
91. Jain, S., Zhu, Y., Qi, C., Kanwar, Y. S., Yeldandi, A. V., Rao, M. S., Reddy, J. K.: Differential expression of the peroxisome proliferator-activated receptor γ (PPARγ) and its coactivators steroid receptor coactivator-1 and PPAR-binding protein PBP in the brown fat, urinary bladder, colon, and breast of the mouse. - Am. J. Pathol. 153, 349-354 (1998).
92. JENSEN, E.V., SUZUKI, T., KAWASHIMA, T., STUMPF, W. E., JUNGBLUT, P. W., DESOMBR, E. R.: A two-step mechanism for the interaction of estradiol with rat uterus. - Proc. natl. Acad. Sci. USA 59, 632-638 (1968).
93. JENSTER, G., TRAPMAN, J., BRINKMANN, A. O.: Nuclear import of human androgen receptor. - Biochem. J. 293, 761-768 (1993).
94. JIANG, G., NEPOMUCENO, L., HOPKINS, K., SLADEK, F. M.: Exclusive homodimerization of the orphan receptor hepatocyte nuclear factor 4 defines a new subclass of nuclear receptors. - Mol. cell. Biol. 15, 5131-5143 (1995).
95. KAMIYA, K., SATO, T., NISHIMURA, N., GOTO, Y., KANO, K., IGUCHI, T.: Expression of estrogen receptor and proto-oncogene messenger ribonucleic acids in reproductive tracts of neonatally diethylstilbestrol-exposed female mice with or without postpuberal estrogen administration. - Exp. clin. Endocrinol. Diabetes 104, 112-122 (1996).
96. KANG, K. I., DEVIN, J., CADEPOND, E, JIBARD, N., GUICHION-MANTEL, A., BAULIEU, E. T., CATELLI, A. M.: In vivo functional protein-protein interaction: nuclear targeted hsp90 shifts cytoplasmic steroid mutants into the nucleus. - Proc. natl. Acad. Sci. USA 91, 340-344 (1994).
97. KATO, S., MANO, H., KUMAZAWA, T., YOSHIZAWA, Y, KOJIMA, R., MASUSHIGE, S.: Effect of retinoid status on α, β and γ retinoic acid receptor mRNA levels in various rat tissues. - Biochem. J. 286, 755-760 (1992).
98. KATZ, D., NIEDERBERGER, C., SLAUGHTER, G. R., COONEY, A. J.: Characterization of germ cell-specific expression of the orphan nuclear receptor, germ cell nuclear factor. - Endocrinology 138, 4364-4372 (1997).
99. Kaufmann, S. H., Okret, S., Wikstrom, A.-C., Gustafsson, J.-A., Shaper, J.: Binding of the glucocorticoid receptor to the rat liver nuclear matrix. The role of disulfide bond formation. - J. biol. Chem. 161, 11962-11967 (1986).
100. KIEBACK, D. G., RUNNEBAUM, I. B., MOEBUS, V. J., KREIENBERG, R., MCCAMANT, S. K., EDWARDS, C. L., JONES, L. A., TSAI, M. J., O'MALLEY, B. W.: Chicken ovalbumin upstream promoter transcription factor (COUP-TF): an orphan steroid receptor with a specific pattern of differential expression in human ovarian cancer cell lines. - Gynecol. Oncol. 51, 167-170 (1993).
101. KING, W. J., GREENE, G. L.: Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells. - Nature 307, 745-749 (1984).
102. Kirkland, J. L., Murthy, L., Stancel, G. M.: Progesterone inhibits the estrogen-induced expression of c-fos messenger ribonucleic acid in the uterus. - Endocrinology 130, 3223-3230 (1992).
103. KLIEWER, S. A., LEHMANN, J. M., MILBURN, M. V., WILLSON, T. M.: The PPARs and PXRs: nuclear xenobiotic receptors that define novel hormone signaling pathways. - Recent Prog. Horm. Res. 54, 345-368 (1999).
104. KOJI, T.: In situ localization of gene-specific transcription regulatory factors by Southwestern histochemistry. - Acta Histochem. Cytochem. (Kyoto) 32, 255-260 (1999).
105. KOJI, T., YAMADA, S., IZUMI, S., NAKANE, P. K.: A new approach to localize glucocordcoid receptor using DNA probe containing glucocorticoid responsive element DNA consensus sequences. - Acta Histochem. Cytochem. (Kyoto) 25, 681-687 (1992).
106. KORACH, K. S.: Estrogen action in the mouse uterus: characterization of the cytosol and nuclear receptor systems. - Endocrinology 104, 1324-1332 (1979).
107. KORACH, K. S., HORIGOME, T., TOMOOKA, Y., YAMASHITA, S., NEWBOLD, R. R., MCLACHLAN, J. A.: Immunodetection of estrogen receptor in epithelial and stromal tissues of neonatal mouse uterus. - Proc. natl. Acad. Sci. USA 85, 3334-3337 (1988).
108. KOSHIYAMA, M., KONISHI, I., NANBU, K., NANBU, Y., MANDAI, M., KOMATSU, T., YAMAMOTO, S., MORI, T., FUJII, S.: Immunohistochemical localization of heat shock proteins HSP70 and HSP90 in the human endometrium: correlation with sex steroid receptors and Ki-67 antigen expression. - J. clin. Endocrinol. Metab. 80, 1106-1112 (1995).
109. KREGE, J. H., HODGIN, J. B., COUSE, J. F., ENMARK, E., WARNER, M., MAHLER, J. F., SAR, M., KORACH, K. S., GUSTAFSSON, J. A., SMITHIES, O.: Generation and reproductive phenotypes of mice lacking estrogen receptor β. - Proc. natl. Acad. Sci. USA 95, 15677-15682 (1998).
110. KREZEL, W., KASTNER, P., CHAMBON, P.: Differential expression of retinoid receptors in the adult mouse central nervous system. - Neuroscience 89, 1291-1300 (1999).
111. KTISTAKI, E., KTISTAKIS, N. T., PAPADOGEORGAKI, E., TALIANIDIS, I.: Recruitment of hepatocyte nuclear factor 4 into specific intranuclear compartments depends on tyrosine phosphorylation that affects its DNA-binding and transactivation potential. - Proc. natl. Acad. Sci. USA 92, 9876-9880 (1995).
112. KUDO, A., FUKUSHIMA, H., KAWAKAMI, H., MATUSDA, M., GOYA, T., HIRANO, H.: Use of serial semithin frozen sections to evaluate the co-localization of estrogen receptors and progesterone receptors in cells of breast cancer tissue. - J. Histochem. Cytochem. 44, 615-620 (1996).
113. KUIPER, G. G., CARLSSON, B., GRANDIEN, K., ENMARK, E., HAGGBLAD, J., NILSSON, S., GUSTAFSSON, J. A.: Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. - Endocrinology 138, 863-870 (1997).
114. KUIPER, G. G., ENMARK, E., PELTO-HUIKKO, M., NILSSON, S., GUSTAFSSON, J. A.: Cloning of a novel receptor expressed in rat prostate and ovary. - Proc. natl. Acad. Sci. USA 93, 5925-5930 (1996).
115. KURITA, T., LEE, K.-J., COOKE, P. S., TAYLOR, J. A., LUBAHN, D. B., CUNHA, G. R.: Paracrine regulation of epithelial progesterone receptor by estradiol in the mouse female reproductive tract. - Biol. Reprod. 62, 821-830 (2000).
116. LAFOND, R. E., KENNEDY, S. W., HARRRISON, R. W., VILLEE, C. A.: Immunohistochemical localization of glucocorticoid receptors in cells, cytoplast, and nucleoplast. - Exp. Cell Res. 175, 52-62 (1988).
117. LASKEY, R. A., DINGWALL, C.: Nuclear shuttling: the default pathway for nuclear proteins? - Cell 74, 585-586 (1993).
118. Lasnitzki, L., Mizuno, T.: Prostatic induction: Interaction of epithelium and mesenchyme from normal wild-type mice and androgen-insensitive mice with testicular feminization. - J. Endocr. 85, 423-428 (1980).
119. LAUBER, A. H., SANDHU, N. P., SCHUCHARD, M., SUBRAMANIAM, M., SPELSBERG, T. C.: Nuclear matrix acceptor binding sites for steroid hormone receptors: A candidate nuclear matrix acceptor protein. - Int. Rev. Cytol. 162B, 337-376 (1995).
120. LAUDET, V.: Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor. - J. mol. Endocrinol. 19, 207-226 (1997).
121. LECHAN, R. M., QI, Y., BERRODIN, T. J., DAVIS, K. D., SCHWARTZ, H. L., STRAIT, K. A., OPPENHEIMER, J. H., LAZAR, M. A.: Immunocytochemical delineation of thyroid hormone receptor β2-like immunoreactivity in the rat central nervous system. - Endocrinology 132, 2461-2469 (1993).
122. LI, S., WASHBURN, K. A., MOORE, R., UNO, T., TENG, C., NEWBOLD, R. R., MCLACHLAN, J. A., NEGISHI, M.: Developmental exposure to diethylstilbestrol elicits demethylation of estrogen-responsive lactoferrin gene in mouse uterus. - Cancer Res. 57, 4356-4359 (1997).
123. LIM, C. S., BAUMANN, C. T., HTUNT, H., XIAN, W., IRIE, M., SMITH, C. L., HANGER, G. L.: Differential localization and activity of the A-and B-forms of the human progesterone receptor using green fluorescent protein chimeras. - Mol. Endocrinol. 13, 366-375 (1999).
124. LIU, J., DEFRANCO, D. B.: Protracted nuclear export of glucocorticoid receptor limits its turnover and does not require the exportin 1/CRM1-directed nuclear export pathway. - Mol. Endocrinol. 14, 40-51 (2000).
125. LOMBES, M., FARMAN, N., OBLIN, M. E., BAULIEU, E. E., BONVALET, J. P., ERLANGER, B. F., GASC, J. M.: Immunohistochemical localization of renal mineral corticoid receptor by using an anti-ideotype antibody that is an internal image of aldosterone. - Proc. natl. Acad. Sci. USA 87, 1086-1088 (1990).
126. MACCHIA, E., NAKAI, A., JANIGA, A., SAKURAI, A., FISFALEN, M. E., GARDNER, P., SOLTANI, K., DEGROOT, L. J.: Characterization of site-specific polyclonal antibodies to c-erbA peptides recognizing human thyroid hormone receptors α 1, α 2, and β and native 3,5,3′-triiodothyronine receptor, and study of tissue distribution of the antigen. - Endocrinology 126, 3232-3239 (1990).
127. MAJDIC, G., MILLAR, M. R., SAUNDERS, P. T.: Immunolocalisation of androgen receptor to interstitial cells in fetal rat testes and to mesenchymal and epithelial cells of associated ducts. - J. Endocrinol. 147, 285-293 (1995).
128. MALAYER, J. R., CHENG, J., WOODS, V. M.: Estrogen responses in bovine fetal uterine cells involve pathways directed by both estrogen response element and activator protein-1. - Biol. Reprod. 60, 1204-1210 (1999).
129. MANGELSDORF, D. J., BORGMEYER, U., HEYMAN, R. A., ZHOU, J. Y., ONG, E. S., ORO, A. E., KAKIZUKA, A., EVANS, R. M.: Characterization of three RXR genes that mediate the action of 9-cis retinoic acid. - Genes Dev. 6, 329-344 (1992).
130. MANGELSDORF, D. J., EVANS, R. M.: The RXR heterodimers and orphan receptors. - Cell 83, 841-850 (1995).
131. MARTIN, P. M., SHERIDAN, P. J.: Towards a new model for the mechanism of action of steroids. - J. Steroid. Biochem. 16, 215-229 (1982).
132. MARTINEZ-BALBAS, M. A., DEY, A., RABINDRAN, S. K., OZATO, K., WU, C.: Displacement of sequence-specific transcription factors from mitotic chromatin. - Cell 83, 29-38 (1995).
133. MARTINS, V. R., PRATT, W.B., TERRACIO, L., HIRST, M. A., RINGOLD, G. M., HOUSLEY, P. R.: Demonstration by confocal microscopy that unliganded overexpressed glucocorticoid receptors are distributed in a nonrandom manner throughout all planes of the nucleus. - Mol. Endocrinol. 5, 217-225 (1991).
134. MATSUI, T., SASHIHARA, S., OH, Y., WAXMAN, S. G.: An orphan nuclear receptor, mRORα, and its spatial expression in adult mouse brain. - Mol. Brain Res. 33, 217-226 (1995).
135. MATSUZAKI, S., FUKAYA, T., SUZUKI, T, MURAKAMI, T., SASANO, H., YAJIMA, A.: Oestrogen receptor α and β mRNA expression in human endometrium throughout the menstrual cycle. - Mol. hum. Reprod. 5, 559-564 (1999).
136. MCCLELLAN, M. C., WEST, N. B., TACHA, D. E., GREENE, G. L., BRENNER, R. M.: Immunocytochemical localization of estrogen receptors in the Macaque reproductive tract with monoclonal antiestrophilins. - Endocrinology 114, 2002-2014 (1984).
137. McEwen, B. S.: Neural gonadal steroid actions. - Science 211, 1303-1311 (1981).
138. McGimsey, W. C., Cidlowsky, J. A., Stumpf, W. E., Sar, M.: Immunocytochemical localization of the glucocorticoid receptor in rat brain, pituitary, liver and thymus with two new polyclonal antipeptide antibodies. - Endocrinology 129, 3064-3072 (1991).
139. MCGOWAN, E. M., CLARKE, C. L: Effect of overexpression of progesterone receptor A on endogenous progestin-sensitive endpoints in breast cancer cells. - Mol. Endocrinol. 13, 1657-1671 (1999).
140. MCLACHLAN, J. A., NEWBOLD, R. R., BULLOCK, B.: Reproductive tract lesions in male mice exposed prenatally to diethylstilbestrol. - Science 190, 991-992 (1975).
141. MENG, X., DEVIN, J., SULLIVAN, W. P., TOFT, D., BAULIEU, E. E., CATELLI, M. G.: Mutational analysis of HSP90α dimerization and subcellular localization: dimer disruption does not impede 'in vivo' interaction with estrogen receptor. - J. Cell Sci. 109, 1677-1687 (1996).
142. METZGER, D. A., KORACH, K. S.: Cell-free interaction of the estrogen receptor with mouse uterine nuclear matrix: Evidence of saturability, specificity, and resistance to KCl extraction. - Endocrinology 126, 2190-2195 (1990).
143. MICHAEL, W. M.: Nucleocytoplasmic shuttling signals: two for the price of one. - Trends Cell Biol. 10, 46-50 (2000).
144. MIETUS-SNYDER, M., SLADEK, F. M., GINSBURG, G. S., KUO, C. F., LADIAS, J. A., DARNELL, J. E. JR., KARATHANASIS, S. K.: Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells. - Mol. cell Biol. 12, 1708-1718 (1992).
145. MIQUEROL, L., LOPEZ, S., CARTIER, N., TULLIEZ, M., RAYMONDJEAN, M., KAHN, A.: Expression of the L-type pyruvate kinase gene and the hepatocyte nuclear factor 4 transcription factor in exocrine and endocrine pancreas. - J. biol. Chem. 269, 8944-8451 (1994).
146. MOR, G., AMIR-ZALTAMAN, Y., BARNARD, G., KOHEN, F.: Characterization of an antiideotypic antibody mimicking the actions of estradiol and its interaction with estrogen receptors. - Endocrinology 130, 3633-3640 (1992).
147. MORAS, D., GRONEMEYER, H.: The nuclear receptor ligand-binding domain: structure and function. - Curr. Opin. Cell Biol. 10, 384-391 (1998).
148. MORIMOTO, M., MORITA, N., OZAWA, H., YOKOYAMA, K., KAWATA, M.: Distribution of glucocorticoid receptor immunoreactivity and mRNA in the rat brain: an immunohistochemical and in situ hybridization study. - Neurosci. Res. 26, 235-269 (1996).
149. MOTE, P. A., BALLEINE, R. L., MCGOWAN, E. M., CLARKE, C. L.: Colocalization of progesterone receptors A and B by dual immunofluorecent histochemistry in human endometrium during the menstrual cycle. - J. clin. Endorinol. Metab. 84, 2963-2971 (1999).
150. MURPHY, L. J., GHAHARY, A.: Uterine insulin-like growth factor-1: Regulation of expression and its role in estrogen-induced uterine proliferation.
151. NAKAGAWA, S., WATANABE, M., INOUE, Y.: Prominent expression of nuclear hormone receptor ROR α in Purkinje cells from early development. - Neurosci. Res. 28, 177-184 (1997).
152. NELSON, K. G., SAKAI, Y., EITZMAN, B., STEED, T., MCLACHLAN, J. A.: Exposure to diethylstilbestrol during a critical developmental period of the mouse reproductive tract leads to persistent induction of two estrogen-regulated genes. - Cell Growth Differ. 5, 595-606 (1994).
153. NELSON, K. G., TAKAHASHI, T., BOSSER, N. L., WALMER, D. K., MCLACHLAN, J. A.: Epidermal growth factor replaces estrogen in the stimulation of female genital-tract growth and differentiation. - Proc. natl. Acad. Sci. USA 88, 21-25 (1991).
154. NELSON, K. G., TAKAHASHI, T., LEE, D. C., LUETTEKE, N. C., BOSSERT, N. L., ROSS, K., EITZMAN, B. E., MCLACHLAN, J. A.: Transforming growth factor-α is a potential mediator of estrogen action in the mouse uterus. - Endocrinology 131, 1657-1664 (1992).
155. NEPHEW, P., PETERS, G. A., KHAN, S. A.: Cellular localization of estradiol-induced c-fos messenger ribonucleic acid in the rat uterus: c-fos expression and uterine cellular proliferation do not correlate strictly. - Endocrinology 136, 3007-3015 (1995).
156. NEWBOLD, R. R., PENTECOST, B. T., YAMASHITA, S., LUM, K., MILLER, J. V., NELSON, P., BLAIR, J., KONG, H., TENG, C. T., MCLACHLAN, J. A.: Female gene expression in the seminal vesicle of mice after prenatal exposure to diethylstilbestrol. - Endocrinology 124, 2568-2576 (1989).
157. OAKLEY, R. H., WEBSTER, J. C., SAR, M., PARKER, C. R. JR., CIDLOWSKI, J. A.: Expression and subcellular distribution of the β-isoform of the human glucocordcoid receptor. - Endocrinology 138, 5028-5038 (1997).
158. Okamura, H., Yamamoto, K., Hayashi, S., Kuroiwa, A., Muramatsu, M.: A polyclonal antibody to the rat oestrogen receptor expressed in Escherichia coli: characterization and application to immunohistochemistry. - J. Endocrinol. 235, 333-341 (1992).
159. OKULICZ, W.C., SAVASTA, A.M., HOBERG, L. M., LONGCOPE, C.: Immunofluorescent analysis of estrogen induction of progesterone receptor in the Rhesus uterus. - Endocrinology 125, 930-934 (1989).
160. O'MALLEY, B. W., SCHARDER, W. T., MANI, S., SMITH, C., WEIGET, N. L., CONNEELY, O. M., CLARK, J. K.: An alternative ligand-independent pathway for activation of steroid receptors. - Rec. Prog. Hormone Res. 50, 333-347 (1995).
161. ONATE, S. A., TSAI, S. Y., TSAI, M. J., O'MALLEY, B. W.: Sequence and characterization of a coacti-˜ vator for the steroid hormone receptor superfamily. - Science 270, 1354-1357 (1995).
162. OPPENHEIMER, J. H., SCHWARTZ, H. L., STRAIT, K. A.: Thyroid hormone action 1994: the plot thickens. - Eur. J. Endocrinol. 130, 15-24 (1994).
163. OPPENHEIMER, J. H., SCHWARTZ, H. L., SURKS, M. I., KOERNER, D., DILLMANN, W. H.: Nuclear receptors and the initiation of thyroid hormone action. - Rec. Prog. Horm. Res. 32, 529-565 (1976).
164. OSAKO, S., BUNICK, D., HAYASHI, Y.: Immunohistochemical observation of the 90 Kd heat shock protein (HSP90): high expression in primordial and pre-meiotic germ cells of male and female rat gonads. - J. Histochem. Cytochem. 43, 647-676 (1995).
165. OTTO, C., REICHARDT, H. M., SCHUTZ, G.: Absence of glucocorticoid receptor-β in mice. - J. biol. Chem. 272, 26665-2668 (1997).
166. PAECH, K., WEBB, P., KUIPER, G. G., NILSSON, S., GUSTAFSSON, J., KUSHNER, P. J., SCANLAN, T. S.: Differential ligand activation of estrogen receptors ERα and ERβ at AP1 sites. - Science 277, 1508-1510 (1997).
167. PARIS, F., WEINBAUER, G., BLUM, V., NIESCHLA, E.: The effect of androgens and antiandrogens on the immunohistochemical localization of the androgen receptor in accessory reproductive organs of male rats. - J. Steroid Biochem. molec. Biol. 48, 129-137 (1994).
168. PARKER, M. G.: Transcriptional activation by oestrogen receptors. - Biochem. Soc. Symp. 63, 45-50 (1998).
169. PARKS, D. J., BLANCHARD, S. G., BLEDSOE, R. K., CHANDRA, G., CONSLER, T. G., KLIEWER, S. A., STIMMEL, J. B., WILLSON, T. M., ZAVACKI, A. M., MOORE, D. D., LEHMANN, J. M.: Bile acids: natural ligands for an orphan nuclear receptor. - Science 284, 1365-1368 (1999).
170. PASSINEN, S., HAVERINEN, M., PEKKI, A., RAUTA, J., PARANKO, J., SYVALA, H., TUOHIMAA, P., YLIKOMI, T.: Only a small portion of the cytoplasmic progesterone receptor is associated with Hsp90 in vivo. - J. cell. Biochem. 74, 458-467 (1999).
171. PASTERKAMP, R. J., YURI, K., VISSER, D. T., HAYASHI, S., KAWATA, M.: The perinatal ontogeny of estrogen receptor-immunoreactivity in the developing male and female rat hypothalamus. -Dev. Brain Res. 91, 300-303 (1996).
172. PEET, D. J., JANOWSKI, B. A., MANGELSDORF, D. J.: The LXRs: a new class of oxysterol receptors. - Curr. Opin. Genet. Dev. 8, 571-575 (1998).
173. PEKKI, A. K.: Different immunoelectron microscopic locations of progesterone receptor and HSP90 in chick oviduct epithelial cells. - J. Histochem. Cytochem. 39, 1095-1101 (1991).
174. PEKKI, A., KOISTINAHO, J., YLIKOMI, T., VILJA, P., WESTPHAL, H., TOUHIMAA, P.: Subcellular localization of unoccupied and occupied glucocorticoid receptor by a new immunohistochemical technique. - J. Steroid Biochem. molec. Biol. 41, 753-756 (1992).
175. PEKKI, A., YLIKOMI, T., SYVALA, H., TUOHIMAA, P.: Progesterone receptor does not form oligomeric (8S), non-DNA-binding complex in intact cell nuclei. - J. cell. Biochem. 58, 95-104 (1995).
176. PEREIRA, F. A., QIU, Y., TSAI, M. J., TSAI, S. Y: Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis. - J. Steroid Biochem. mol. Biol. 53, 503-508 (1995).
177. PERROT-APPLANAT, M., GROYER-PICARD, M.-T., LOGEAT, F., MILGROM, E.: Ultrastructural localization of the progesterone receptor by an immunogold method: Effect of hormone administration. - J. Cell Biol. 102, 1191-1199 (1986).
178. PERROT-APPLANAT, M., LESCOP, P., MILGROM, E.: The cytoskeleton and the cellular traffic of the progesterone receptor. - J. Cell Biol. 119, 337-348 (1992).
179. PERROT-APPLANAT, M., LOGEAT, F., GROYER-PICARD, M. T., MILGROM, E.: Immunocytochemical study of mammalian progesterone receptor using monoclonal antibodies. - Endocrinology 116, 1473-1484 (1985).
180. PFAHL, M.: Nuclear receptor/AP-1 interaction. - Endocr. Rev. 14, 651-658 (1993).
181. PICARD, D., KUMAR, V., CHAMBON, P., YAMAMOTO, K. R.: Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors. - Cell Reg. 1, 291-299 (1990).
182. PRATT, W. B., TOFT, D. O.: Steroid receptor interactions with heat shock protein and immunophilin chaperones. - Endocr. Rev. 18, 306-360 (1997).
183. PRESS, M. F., GREENE, G. L.: Localization of progesterone receptor with monoclonal antibodies to the human progestin receptor. - Endocrinology 122, 1165-1175 (1988).
184. PRESS, M. F., NOUSEK-GOEBK, N. A., GREENE, G. L.: Immunoelectron microscopic localization of estrogen receptor with monoclonal estrophilin antibodies. - J. Histochem. Cytochem. 33, 915-924 (1985).
185. PRESS, M. F., NOUSEK-GOEBL, N., KING, W. J., HERBST, A. L., GREENE, G. L.: Immunohistochemical assessment of estrogen receptor distribution in the human endometrium throughout the menstrual cycle. - Lab. Invest. 51, 495-503 (1984).
186. PRINS, G. S., BIRCH, L.: Immunohistochemical analysis of androgen receptor along the ducts of the separate rat prostate lobes after androgen withdrawal and replacement. - Endocrinology 132, 169-178 (1993).
187. QIU, Y., TSAI, S. Y., TSAI, M. J.: COUP-TF An orphan member of the steroid/thyroid hormone receptor superfamily. - Trends Endocrinol. Metab. 5, 234-239 (1994).
188. RADDATZ, D., HENNEKEN, M., ARMBRUST, T., RAMADORI, G.: Subcellular distribution of glucocorticoid receptor in cultured rat and human liver-derived cells and cell lines: influence of dexamethasone. - Hepatology 24, 928-933 (1996).
189. RAMAYYA, M. S., ZHOU, J., KINO, T., SEGARS, J. H., BONDY, C. A., CHROUSOS, G. P.: Steroidogenic factor 1 messenger ribonucleic acid expression in steroidogenic and nonsteroidogenic human tissues: Northern blot and in situ hybridization studies. - J. clin. Endocrinol. Metab. 82, 1799-1806 (1997).
190. REICHMANN, E., SCHWARZ, H., DEINER, E. M., LEITNER, I., EILERS, M., BERGER, J., BAUSSLINGER, M., BEUG, H.: Activation of an inducible c-FosER fusion protein causes loss of epithelial polarity and triggers epithelial-fibroblastoid cell conversion. - Cell 71, 1103-1116 (1992).
191. 3 receptors (VDR) in human skin. A comparison of five antibodies. - Pathol. Res. Pract. 192, 281-289 (1996).
192. REICHRATH, J., MITTMANN, M., KAMRADT, J., MULLER, S. M.: Expression of retinoid-X receptors (-α,-β,-γ) and retinoic acid receptors (-α,-β,-γ) in normal human skin: an immunohistological evaluation. - Histochem. J. 29, 127-133 (1997).
193. ROBERTSON, N. M., SCHULMAN, G., KARNIK, S., ALNEMRI, E., LITWACK, G.: Demonstration of nuclear translocation of the mineralocorticoid receptor (MR) using an anti-MR antibody and confocal laser scanning microscopy. - Mol. Endocrinol. 7, 1226-1239 (1993).
194. RUBERTE, E., DOLLE, P., CHAMBON, P., MORRISS-KAY, G.: Retinoic acid receptors and cellular retinoid binding proteins. II. Their differential pattern of transcription during early morphogenesis in mouse embryos. - Development 111, 45-60 (1991).
195. RUSSELL, D. W.: Nuclear orphan receptors control cholesterol catabolism. - Cell 97, 539-542 (1999).
196. SAJI, S., JENSEN, E.V., NILSSON, S., RYLANDER, T., WARNER, M., GUSTAFSSON, J. A.: Estrogen receptors α and β in the rodent mammary gland. - Proc. natl. Acad. Sci. USA 97, 337-342 (2000).
197. SALO, L. K., MAKELA, S. I., STANCEL, G. M., SANTTI, R. S.: Neonatal exposure to diethylstilbestrol permanently alters the basal and 17β-estradiol induced expression of c-fos proto-oncogene in mouse urethroprostatic complex. - Mol. cell. Endocrinol. 126, 133-141 (1997).
198. SANNO, N., SUGAWARA, A., TERAMOTO, A., ABE, Y., YEN, P. M., CHIN, W. W., OSAMURA, R. Y.: Immunohistochemical expression of retinoid X receptor isoforms in human pituitaries and pituitary adenomas. - Neuroendocrinology 65, 299-306 (1997).
199. SAR, M., LUBAHN, D. B., FRENCH, F. S., WILSON, E. M.: Immunohistochemical localization of androgen receptor in rat and human tissues. - Endocrinology 127, 3180-3186 (1990).
200. SASANO, H., FUKUSHIMA, K., SASAKI, I., MATSUNO, S., NAGURA, H., KROZOWSKI, Z. S.: Immunolocalization of mineralocorticoid receptor in human kidney, pancreas, salivary, mammary and sweat glands: a light and electron microscopic immunohistochemical study. - J. Endocrinol. 132, 305-310 (1992).
201. SATO, T, CHIBA, A., HAYASHI, S., OKUMURA, H., OHTA, Y., TAKASUGI, N., IGUCHI, T: Induction of estrogen receptor and cell division in genital tracts of male mice by neonatal exposure to diethylstilbestrol. - Reprod. Toxicol. 8, 145-153 (1994).
202. SATO, T, OHTA, Y, OKAMURA, H., HAYASHI, S., IGUCHI, T.: Estrogen receptor (ER) and its messenger ribonucleic acid expression in the genital tract of female mice exposed neonatally to tamoxifen and diethystilbestrol. - Anat. Rec. 244, 374-385 (1996).
203. SATO, T., OKAMURA, H., OHTA, Y., HAYASHI, S., TAKAMATSU, Y, TAKASUGI, N., IGUCHI, T.: Estrogen receptor expression in the genital tract of female mice treated neonatally with diethylstilbestrol. - In Vivo 6, 151-156 (1992).
204. SAUNDERS, P. T. K., MAGUIRE, S. M., GAUGHAN, J., MILLAR, M. R.: Expression of oestrogen receptor beta (ER β) in multiple rat tissues visualised by immunohistochemistry. - J. Endocrinol. 154, R13-16 (1997).
205. SAVORY, J. G. A., HSU, B., LAQUIAN, I. R., GIFFIN, W., REICH, T., HACHE, R. J. G., LEFEBVRE, Y. A.: Discrimination between NL1- and NL2-mediated nuclear localization of glucocorticoid receptor. - Mol. cell. Biol. 19, 1025-1037 (1999).
206. SCHAEREN-WIEMERS, N., ANDRE, E., KAPFHAMMER, J. P., BECKER-ANDRE, M.: The expression pattern of the orphan nuclear receptor RORβ in the developing and adult rat nervous system suggests a role in the processing of sensory information and in circadian rhythm. - Eur. J. Neurosci. 9, 2687-2701 (1997).
207. SCHMIDT-ZACHMANN, M. S., DARGEMONT, C., KUHN, L. C., NIGG, E. A.: Nuclear export of proteins: the role of nuclear retention. - Cell 74, 493-504 (1993).
208. SHAN, L. X., ZHU, L. J., BARDIN, C. W., HARDY, M. P.: Quantitative analysis of androgen receptor messenger ribonucleic acid in developing Leydig cells and Sertoli cells by in situ hybridization. - Endocrinology 136, 3856-3862 (1995).
209. 3H-estradiol or its metabolites in the central nervous system of the developing rat. - Endocrinology 94, 1386-1390 (1974).
210. SHI, S. R., CHAIWUN, B., YOUNG, L., COTE, R. J., TAYLOR, C. R.: Antigen retrieval technique utilizing citrate buffer or urea solution for immunohistochemical demonstration of androgen receptor in formalin-fixed paraffin sections. - J. Histochem. Cytochem. 41, 1599-1604 (1993).
211. SHIM, W. S., DIRENZO, J., DECAPRIO, J. A., SANTEN, R. J., BROWN, M., JENG, M. H.: Segregation of steroid receptor coactivator-1 from steroid receptors in mammary epithelium. - Proc. natl. Acad. Sci. USA 96, 208-213 (1999).
212. SHINODA, K., LEI, H., YOSHII, H., NOMURA, M., NAGANO, M., SHIBA, H., SASAKI, H., OSAWA, Y., NINOMIYA, Y, NIWA, O., MOROHASHI, K., LI, E.: Developmental defects of the ventromedial hypothalamic nucleus and pituitary gonadotroph in the Ftz-F1 disrupted mice. - Dev. Dyn. 204, 22-29 (1995).
213. SHINTAKU, I. P., SAID, J. W.: Detection of estrogen receptors with monoclonal antibodies in routinely processed formalin-fixed paraffin sections of breast carcinoma. Use of DNase pretreatment to enhance sensitivity of the reaction. - Am. J. clin. Pathol. 87, 161-167 (1987).
214. SHUGHRUE, P. J., LANE, M. V., SCRIMO, P. J., MERCHENTHALER, I.: Comprehensive distribution of estrogen receptor-α (ER-α) and β (ER-β) mRNA in the rat pituitary, gonad, and reproductive tract. - Steroids 63, 498-504 (1998a).
215. SHUGHRUE, P. J., SCRIMO, P. J., MERCHENTHALER, I.: Evidence for the colocalization of estrogen receptor-β mRNA and estrogen receptor-α immunoreactivity in neurons of the rat forebrain. - Endocrinology 139, 5267-5270 (1998b).
216. SHYAMALA, G., YANG, X., SILBERSTEIN, G., BARCELLOS-HOFF, M. H., DALE, E.: Transgenic mice carriyng an imbalance in the native ratio of A to B forms of progesterone receptor exhibit developmental abnormalities in mammary glands. - Proc. natl. Acad. Sci. USA 95, 696-701 (1998).
217. SLADEK, F. M., ZHONG, W. M., LAI, E., DARNELL, J. E. Jr.: Liver-enriched transcription factor HNF-4 is a novel member of the steroid hormone receptor superfamily. - Genes Dev. 4, 2353-2365 (1990).
218. SMITH, D. R: Dynamics of heat shock protein 90-progesterone receptor binding and the disactivation loop model for steroid receptor complexes. - Mol. Endocrinol. 7, 1418-1429 (1993).
219. STENOIEN, D. L., MANCINI, M. G., PATEL, K., ALLEGRETTO, E. A., SMITH, C. L., MANCINI, M. A.: Subnuclear trafficking of estrogen receptor-α and steroid receptor coactivator-1. - Mol. Endocrinol. 14, 518-534 (2000).
220. STOECKLIN, E., WISSLER, M., SCHAETZLE, D., PFITZNER, E., GRONER, B.: Interactions in the transcriptional regulation exerted by Stat5 and by members of the steroid hormone receptor family. - J. Steroid Biochem. mol. Biol. 69, 195-204 (1999).
221. STUMPF, W. E.: Vitamin D sites and mechanisms of action: a histochemical perspective. Reflections on the utility of autoradiography and cytopharmacology for drug targeting. - Histochem. Cell Biol. 104, 417-427 (1995).
222. STUMPF, W. E., NARBAITZ, R., SAR, M.: Estrogen receptors in the fetal mouse. - J. Steroid Biochem. 12, 55-64 (1980).
223. STUMPF, W. E., SAR, M.: Autoradiographic techniques for localizing steroid hormones. - Meth. Enzymol. 36, 135-156 (1975).
224. SUGAWARA, A., YEN, P. M., QI, Y., LECHAN, R. M., CHIN, W. W.: Isoform-specific retinoid-X receptor (RXR) antibodies detect differential expression of RXR proteins in the pituitary gland. - Endocrinology 136, 1766-1774 (1995).
225. SUSENS, U., AGUILUZ, J. B., EVANS, R. M., BORGMEYER, U.: The germ cell nuclear factor mGCNF is expressed in the developing nervous system. - Dev. Neurosci. 19, 410-420 (1997).
226. SYVALA, H., PEKKI, A., BLAUER, M., PASANEN, S., MAKINEN, E., YLIKOMI, T., TUOHIMAA, P.: Hormone-dependent changes in A and B forms of progesterone receptor. - J. Steroid Biochem. molec. Biol. 55, 517-524 (1996).
227. TAGUCHI, O., BIGSBY, R. M., CUNHA, G. R.: Estrogen responsiveness and the estrogen receptor during development of the murine female reproductive tract. - Develop. Growth Differ. 30, 301-311 (1988).
228. TAKAHASHI, T., EITZMAN, B., BOSSERT, N. L., WALMER, D., SPARROW, K., FLANDERS, K. C., MCLACHLAN, J. A., NELSON, K. G.: Transforming growth factors β1, β2, and β3 messenger RNA and protein expression in mouse uterus and vagina during estrogen-induced growth: a comparison to other estrogen-regulated genes. - Cell Growth Differ. 5, 919-935 (1994).
229. TAKASUGI, N.: Cytological basis for permanent vaginal changes in mice treated neonatally with steroid hormones. - Int. Rev. Cytol. 44, 193 (1976).
230. TAKEDA, H., CHANG, C.: Immunohistochemical and in-situ hybridization analysis of androgen receptor expression during the development of the mouse prostate gland. - J. Endocrinol. 129, 83-89 (1991).
231. TAKEDA, H., MIZUNO, T., LASNITZKI, I.: Autoradiographic studies of androgen-binding sites in the rat urogenital sinus and postnatal prostate. - J. Endocrinol. 104, 87-92 (1985).
232. TANG, Y., DEFRANCO, D. B.: ATP-dependent release of glucocorticoid receptors from the nuclear matrix. - Mol. cell. Biol. 16, 1989-2001 (1996).
233. TAYLOR, C. R., SHI, S. R., CHAIWUN, B., YOUNG, L., IMAM, S. A., COTE, R. J.: Strategies for improving the immunohistochemical staining of various intranuclear prognostic markers in formalin-paraffin sections: androgen receptor, estrogen receptor, progesterone receptor, p53 protein, proliferating cell nuclear antigen, and Ki-67 antigen revealed by antigen retrieval techniques. - Hum. Pathol. 25, 263-270 (1994).
234. TORCHIA, J., GLASS, C., ROSENFELD, M. G.: Co-activators and co-repressors in the integration of transcriptional responses. - Curr. Opin. Cell Biol. 10, 373-383 (1998).
235. TRAISH, A. M., MULLER, R. E., WOTIZ, H. H.: Binding of estrogen receptor to uterine nuclei. Salt-extractable versus salt-resistant receptor-estrogen complexes. - J. biol. Chem. 252, 6823-6830 (1977).
236. TRENDELENBURG, M. F.: The RNA polymerase I-specific transcription initiation factor UBF is associated with transcriptionally active and inactive ribosomal genes. - Chromosoma 102, 599-611 (1993).
237. TSAI, M-J., CLARK, J. H., SCHRADER, W. T., O'MALLEY, B. W.: Mechanisms of action of hormones that act as transcription-regulatory factors. - In: WILSON, J. D., FOSTER, D. N., KRONENBERG, H. M., LARSEN, P. R. (eds.), Williams Textbook of Endocrinology (9th edition). W. B. Saunders Company, Philadelphia (1998).
238. TSAI, S. Y., TSAI, M. J.: Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. - Endocr. Rev. 18, 229-240 (1997).
239. TSURUO, Y., ISHIMURA, K., FUJITA, H., OSAWA, Y.: Immunocytochemical localization of aromatase-containing neurons in the rat brain during pre- and postnatal development. - Cell Tissue Res. 278, 29-39 (1994).
240. TUOHIMAA, P., PEKKI, A., BLAUER, M., JOENSUU, T., VILJA, P., YLIKOMI, T.: Nuclear progesterone receptor is mainly heat shock protein 90-free in vivo. - Proc. natl. Acad. Sci. USA 90, 5848-5852 (1993).
241. TYAGI, R. K., AMAZIT, L., LESCOP, P., MILGROM, E., GUIOCHON-MANTEL, A.: Mechanisms of progesterone receptor export from nuclei: role of nuclear localization signal, nuclear export signal, and ran guanosine triphosphate. - Mol. Endocrinol. 12, 1684-1695 (1998).
242. VAN STEENSEL, B., BRINK, M., VAN DER MEULEN, K., VAN BINNENDIJK, E. P., WANSINK, D. G., DE JONG, L., DE KLOET, E. R., VAN DRIEL, R.: Localization of the glucocorticoid receptor in discrete clusters in the cell nucleus. - J. Cell Sci. 108, 3003-3011 (1995a).
243. VAN STEENSEL, B., JENSTER, G., DAMM, K., BRINKMANN, A. O., VAN DRIEL, R.: Domains of human androgen receptor and glucocorticoid receptor involved in binding to the nuclear matrix. - J. cell. Biochem. 57, 465-478 (1995b).
244. VEGETO, E., SHAHBAZ, M. M., WEN, D. X., GOLDMAN, M. E., O'MALLEY, B. W., MCDONNELL, D. P.: Human progesterone receptor A form is a cell- and promoter-specific repressor of human progesterone receptor B function. - Mol. Endocrinol. 7, 1244-1255 (1993).
245. VORNBERGER, W., PRINS, G., MUSTO, N. A., SUAREZ-QUIAN, C. A.: Androgen receptor distribution in rat testis: new implications for androgen regulation of spermatogenesis. - Endocrinology 134, 2307-2316 (1994).
246. 3. - Biochem. Biophys. Res. Commun. 98, 990-996 (1981).
247. WANG, H., CRITCHLEY, H. O., KELLY, R. W., SHEN, D., BAIRD, D. T.: Progesterone receptor subtype B is differentially regulated in human endometrial stroma. - Mol. hum. Reprod. 4, 409-412 (1998).
248. WELSHONS, W. V., LIEBERMAN, M. F., GORSKI, J.: Nuclear localization of unoccupied oestrogen receptor. - Nature 307, 747-749 (1984).
249. WEST, N. B., CHANGE, C., LIAO, S., BRENNER, R. M.: Localization and regulation of estrogen, progestin and androgen receptors in the seminal vesicles of the rhesus monkey. - J. Steroid Biochem. molec. Biol. 37, 11-21 (1990).
250. WIKSTROM, A.C., BEKKE, O., OKRET, S., BRONNEGARD, M., GUSTAFSSON, J. A.: Intracellular localization of the glucocorticoid receptor: evidence for cytoplasmic and nuclear localization. - Endocrinology 120, 1232-1242 (1987).
251. WILLY, P. J., MANGELSDORF, D. J.: Nuclear orphan receptors: the search for novel ligands and signaling pathways. - In: O'MALLEY, B. W. (ed.), Hormone and signaling, Vol. 1, pp. 307-358. - Academic Press, San Diego 1998.
252. WILSON, C. M., MCPHAUL, M. J.: A and B forms of the androgen receptor are expressed in a variety of human tissues. - Mol. cell. Endocrinol. 120, 51-57 (1996).
253. WONG, M., IKEDA, Y., Luo, X., CARON, K. M., WEBER, T. J., SWAIN, A., SCHIMMER, B. P., PARKER, K. L.: Steroidogenic factor 1 plays multiple roles in endocrine development and function. - Recent. Prog Horm. Res. 52, 167-184 (1997).
254. WYSZOMIERSKI, S. L., YEH, J., ROSEN, J. M.: Glucocorticoid receptor/signal transducer and activator of transcription 5 (STAT5) interactions enhance STATS activation by prolonging STAT5 DNA binding and tyrosine phosphorylation. - Mol. Endocrinol. 13, 330-343 (1999).
255. Xu, J., Qiu, Y., DeMayo, F. J., Tsai, S. Y., Tsai, M. J., O'Malley, B. W.: Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. - Science 279, 1922-1925 (1998).
256. YAMAGATA, K., FURUTA, H., ODA, N., KAISAKI, P. J., MENZEL, S., COX, N. J., FAJANS, S. S., SIGNORINI, S., STOFFEL, M., BELL, G. I.: Mutations in the hepatocyte nuclear factor-4α gene in maturity-onset diabetes of the young. - Nature 384, 458-460 (1996).
257. YAMAGATA, T., MOMOI, M. Y., YANAGISAWA, M., KUMAGAI, H., YAMAKADO, M., MOMOI, T.: Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. - Dev. Brain Res. 77, 163-176 (1994).
258. YAMASHITA, S.: Intranuclear localization of hormone-occupied and unoccupied estrogen receptors in the mouse uterus: Application of 1 nm immunogold-silver enhancement procedure to ultrathin frozen sections. - J. Electron Microsc. 44, 22-29 (1995).
259. -: Subcellular localization of steroid hormone receptors during mitosis. - Acta Histochem. Cytochem. (Kyoto) 31, 393-399 (1998a).
260. -: Localization and functions of steroid hormone receptors. - Histol. Histopathol. 13, 255-270 (1998b).
261. YAMASHITA, S., KORACH, K. S.: Immunological analysis of the biochemical properties of the uterine estrogen receptor. - Biol. Reprod. 40, 1275-1285 (1989a).
262. -: A modified immunohistochemical procedure for the detection of estrogen receptor in mouse tissues. - Histochemistry 90, 325-330 (1989b).
263. YAMASHITA, S., NEWBOLD, R. R., MCLACHLAN, J. A., KORACH, K. S.: Developmental pattern of estrogen receptor expression in female mouse genital tracts. - Endocrinology 125, 2888-2896 (1989c).
264. -: The role of the estrogen receptor in uterine epithelial proliferation and cytodifferentiation in neonatal mice. - Endocrinology 127, 2456-2463 (1990).
265. YAMASHITA, S., SOGO, T., YASUDA, K.: Immunolocalization of aldolase A subunit using monoclonal antibody in rabbit tissues. - Acta Histochem. Cytochem. (Kyoto) 30, 601-608 (1997).
266. YAMASHITA, S., TAKAYANAGI, A., SHIMIZU, N.: Temporal and cell-type specific expression of c-fos and c-jun protooncogenes in the mouse uterus after estrogen stimulation. - Endocrinology 137, 5468-5475 (1996).
267. -: Expression of c-fos and c-jun protooncogenes in the uterusof neonatally estrogenized mouse. - Italian J. Anat. Embryol. 104 (suppl n. 1), 774 (1999).
268. YASUDA, K., YAMASHITA, S., AISO, S., SHIOZAWA, M., KOMATSU, T.: Immunohistochemical study of γ-glutamyl transpeptidase with monoclonal antibodies. I Preparation and characterization of monoclonal antibodies to γ-glutamyl transpeptidase. - Acta Histochem. Cytochem. (Kyoto) 19, 589-600 (1986).
269. YEN, P. M., CHIN, W. W.: New advances in understanding the molecular mechanisms of thyroid hormone action. - Trends Endocrinol. Metab. 5, 65-72 (1994).
270. YLIKOMI, T, BOCQUEL, M. T., BERRY, M., GRONEMEYER, H., CHAMBON, P.: Cooperation of protosignals for nuclear accumulation of estrogen and progesterone receptors. - EMBO J. 11, 3681-3694 (1992).
271. YLIKOMI, T., WURTZ, J. M., SYVALA, H., PASSINEN, S., PEKKI, A., HAVERINEN, M., BLAUER, M., TUOHIMAA, P., GRONEMEYER, H.: Reappraisal of the role of heat shock proteins as regulators of steroid receptor activity. - Grit. Rev. Biochem. mol. Biol. 33, 437-466 (1998).
272. YOKOSUKA, M., OKAMURA, H., HAYASHI, S.: Postnatal development and sex difference in neurons containing estrogen receptor-α immunoreactivity in the preoptic brain, the diencephalon, and the amygdala in the rat. - J. comp. Neurol. 389, 81-93 (1997).
273. YONEDA, Y: Nuclear pore-targeting complex and its role on nuclear protein transport. - Arch. Histol. Cytol. 59, 97-107 (1996).
274. YONEDA, Y., HIEDA, M., NAGOSHI, E., MIYAMOTO, Y.: Nucleocytoplasmic protein transport and recycling of Ran. - Cell Struct. Funct. 24, 425-433 (1999).
275. ZHOU, X., KUDO, A., KAWAKAMI, H., HIRANO, H.: Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development. - Anat. Rec. 245, 509-518 (1996).
276. ZHOU, Z. X., SAR, M., SIMENTAL, J. A., LANE, M. V., WILSON, E. M.: A ligand-dependent bipartite nuclear targeting signal in the human androgen receptor. Requirement for the DNA-binding domain and modulation by NH2-terminal and carboxyl-terminal sequences. - J. biol. Chem. 269, 13115-13123 (1994).
277. ZHUANG, Y. H., BLAUER, M., PEKKI, A., TUOHIMAA, P.: Subcellular localization of androgen receptor in rat prostate, seminal vesicle and human osteosarcoma MG-63 cells. - J. Steroid Biochem. molec. Biol. 41, 693-696 (1992).