Intracellular traffic of steroid hormone receptors

Journal of Steroid Biochemistry and Molecular Biology

Volumn 56, Issue 1-6, 1996, Pages 3-9

  Guiochon Mantel, Anne ^a   Delabre, Karine ^a   Lescop, Pierre ^a   Milgrom, Edwin ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGESTAGEN; BETA GALACTOSIDASE; HORMONE RECEPTOR; MIFEPRISTONE; ONAPRISTONE; PROGESTERONE RECEPTOR; GONANE DERIVATIVE; HORMONE ANTAGONIST; HYBRID PROTEIN; SIGNAL PEPTIDE; STEROID RECEPTOR; ZINC FINGER PROTEIN;

CELL NUCLEUS MEMBRANE; CONFERENCE PAPER; CYTOCHEMISTRY; HUMAN; INTRACELLULAR TRANSPORT; NONHUMAN; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CELL NUCLEUS; CYTOPLASM; GENE EXPRESSION REGULATION; GENETICS; HAMSTER; METABOLISM; MOLECULAR GENETICS; MOUSE; PHYSIOLOGY; REVIEW; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL;

AMINO ACID SEQUENCE; ANIMALS; BETA-GALACTOSIDASE; BIOLOGICAL TRANSPORT; CELL LINE; CELL NUCLEUS; CRICETINAE; CYTOPLASM; GENE EXPRESSION REGULATION; GONANES; HORMONE ANTAGONISTS; HUMANS; MICE; MIFEPRISTONE; MOLECULAR SEQUENCE DATA; NUCLEAR ENVELOPE; PROTEIN SORTING SIGNALS; RECEPTORS, PROGESTERONE; RECEPTORS, STEROID; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; ZINC FINGERS;

EID: 0029868723     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-0760(95)00268-5     Document Type: Conference Paper

References (64)

1. Jensen T., Suzuki T., Kawashima T., Stumpf W. W., Jungblut P. W. and DeSombre E. R.: A two-step mechanism for the interaction of oestradiol with the rat uterus. Proc. Natn. Acad. Sci. U.S.A. 59 (1968) 632-638.
2. Gorski J., Toft D., Shyamala G., Smith D. and Notides A.: Hormone receptors: studies on the interaction of estrogen with the uterus. Rec. Prog. Horm. Res. 24 (1968) 45-81.
3. Greene G. L., Fitch F. W. and Jensen E. V.: Monoclonal antibodies to estrophilin: probes for the study of estrogen receptors. Proc. Natn. Acad. Sci. U.S.A. 77 (1980) 157-161.
4. Logeat F., Vu Hai M. T., Fournier A., Legrain P., Buttin G. and Milgrom E.: Monoclonal anitbodies to rabbit progesterone receptor: crossreaction with other mammalian progesterone receptors. Proc. Natn. Acad. Sci. U.S.A. 80 (1983) 6456-6459.
5. Sullivan W. P., Beito T. G., Proper J., Kreo C. J. and Toft D. O.: Preparation of monoclonal antibodies to the avian progesterone receptor. Endocrinology 119 (1986) 1549-1557.
6. Okret S., Wikström A. C., Wrange O., Andersson B. and Gustafsson J. A.: Monoclonal antibodies against the rat liver glucocorticoid receptor. Proc. Natn. Acad. Sci. U.S.A. 81 (1984) 1609-1613.
7. King W. J. and Greene G. L.: Monoclonal antibodies localize oestrogen receptor in the nuclei of target cells. Nature 307 (1984) 745-747.
8. Perrot-Applanat M., Logeat F., Groyer-Picard M. T. and Milgrom E.: Immunocytochemical study of mammalian progesterone receptor using monoclonal antibodies. Endocrinology 116 (1985) 1473-1484.
9. Welshons W. V., Lieberman M. E. and Gorski J.: Nuclear localization of unoccupied oestrogen receptors. Nature 307 (1984) 747-749.
10. Fuxe K., Wikström A. C., Okret S., Agnati L. F., Harfstrand A., Yu Z. Y., Granholm L., Zoil M., Vale W. and Gustafsson J. A.: Mapping of glucocorticoid receptor immunoreactive neurons in the rat tel- and diencephalon using a monoclonal antibody against rat liver glucocorticoid receptor. Endocrinology 117 (1985) 1803-1812.
11. Wikström A. C., Bakke O., Okret S., Brönnegard M. and Gustafsson J. A.: Intracellular localization of the glucocorticoid receptor: evidence for cytoplasmic and nuclear localization. Endocrinology 120 (1987) 1232-1242.
12. Rossini G. P. and Malaguti C.: Nanomolar concentrations of untransformed glucocorticoid receptor in nuclei intact cells. J. Steroid Biochem. Molec. Biol. 51 (1994) 291-298.
13. Akner G., Wikstrom A. C. and Gustafsson J. A.: Subcellular distribution of the glucocorticoid receptor and evidence for its association with microtubules. J. Steroid Biochem. Molec. Biol. 52 (1995) 1-16.
14. 3 cells. Endocrinology 117 (1985) 2140-2147.
15. Sanchez E. R., Hirst M., Scherrer L. C., Tang H. Y., Welsh M. J., Harmon J. M., Simons S. S., Ringold G. M. and Pratt W. B.: Hormone-free mouse glucocorticoid receptors overexpressed in Chinese hamster ovary cells are localized to the nucleus and are associated with both hsp70 and hsp90. J. Biol. Chem. 265 (1990) 20,123-20,130.
16. Martins V. R., Pratt W. B., Terracio L., Hirst M. A., Ringold G. M. and Housley P. R.: Demonstration by confocal microscopy that unliganded overexpressed glucocorticoid receptors are distributed in a nonrandom manner throughout all planes of the nucleus. Molec. Endocr. 5 (1991) 217-225.
17. Brink M., Humbel B. M., De Kloet E. R. and Van Driel R.: The unliganded glucocorticoid receptor is localized in the nucleus, not in the cytoplasm. Endocrinology 130 (1992) 3575-3581.
18. Husmann D. A., Wilson C. M., McPhaul M. J., Tilley W. D. and Wilson J. D.: Antipeptides antibodies to two distinct regions of the androgen receptor localize the receptor protein to the nuclei of target cells in the rat and human prostate. Endocrinology 126 (1990) 2359-2368.
19. Sar M., Lubahn D. B., French F. S. and Wilson E. M.: Immunohistochemical localization of the androgen receptor in rat and human tissues. Endocrinology 127 (1990) 3180-3186.
20. Simental J. A., Sar M., Lane M. V., French F. S. and Wilson E. M.: Transcriptional activation and nuclear targeting signals of the human androgen receptor. J. Biol. Chem. 266 (1991) 510-518.
21. Jenster G., Trapman J. and Brinkmann A. O.: Nuclear import of the human androgen receptor. Biochem. J. 293 (1993) 761-768.
22. Lombes M., Farman N., Oblin M. E., Baulieu E. E., Bonvalet J. P., Erlanger B. F. and Gasc J. M.: Immunohistochemical localization of renal mineralocorticoid receptor by using an anti-idiotypic antibody that is an internal image of aldosterone. Proc. Natn. Acad. Sci. U.S.A. 87 (1990) 1086-1088.
23. Farman N., Oblin M. E., Lombes M., Delahaye F., Westphal H. M., Bonvalet J. P. and Gasc J. M.: Immunolocalization of gluco- and mineralocorticoid receptors in rabbit kidney. Am. J. Physiol. 260 (1991) C226-C233.
24. Lombes M., Binart N., Delahaye F., Baulieu E. E. and Rafestin-Oblin M. E.: Differential intracellular localization of human mineralocorticoid receptor on binding of agonists and antagonists. Biochem. J. 302 (1994) 191-197.
25. Robertson N. M., Schulman G., Karnik S., Alnemri E. and Litwack G. : Demonstration of nuclear translocation of the mineralocorticoid receptor (MR) using an anti-MR antibody and confocal laser scanning microscopy. Molec. Endocr. 7 (1993) 1226-1239.
26. Dingwall C. and Laskey R.: The nuclear membrane. Science 258 (1992) 942-947.
27. Breeuwer M. and Goldfarb D. S.: Facilitated nuclear transport of histone H1 and other small nucleophilic proteins. Cell 60 (1990) 999-1008.
28. Dingwall C. and Laskey R. A.: Nuclear targeting sequences - a consensus? Trends Biochem. Sci. 16 (1991) 478-481.
29. Kalderon D., Roberts B. L., Richardson W. D. and Smith A. E.: A short aminoacid sequence able to specify nuclear location. Cell 39 (1984) 499-509.
30. Lanford R. E., Kanda P. and Kennedy R. C.: Induction of nuclear transport with a synthetic peptide homologous to the SV40 antigen transport signal. Cell 46 (1986) 575-582.
31. Robbins J., Dilworth S. M., Laskey R. A. and Dingwall C.: Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequence. Cell 64 (1991) 615-623.
32. Newmeyer D. D. and Forbes D. J.: Nuclear import can be separated into distinct steps in vitro: nuclear pore binding and translocation. Cell 52 (1988) 641-653.
33. Richardson W. D., Mills A. D., Dilworth S. M., Laskey R. A. and Dingwall C.: Nuclear protein migration involves two steps: rapid binding at the nuclear envelope followed by slower translocation through nuclear pores. Cell 52 (1988) 655-644.
34. Powers M. A. and Forbes D. J.: Cytosolic factors in nuclear transport: what's importin? Cell 79 (1994) 931-934.
35. Picard D. and Yamamoto K. R.: Two signals mediate hormone-dependent nuclear localization of the glucocorticoid receptor. EMBO J. 6 (1987) 3333-3340.
36. Cadepond F., Gasc J. M., Delahaye F., Jibard N., Schweizer-Groyer G., Segard-Maurel I., Evans R. and Baulieu E. E.: Hormonal regulation of the nuclear localization signals of the glucocorticoid receptor. Exp. Cell. Res. 201 (1992) 99-108.
37. Guiochon-Mantel A., Loosfelt H., Lescop P., Sar S., Atger M., Perrot-Applanat M. and Milgrom E.: Mechanisms of nuclear localization of the progesterone receptor: evidence for interaction between monomers. Cell 57 (1989) 1147-1154.
38. Ylikomi T., Bocquel M. T., Berry M., Gronemeyer H. and Chambon P.: Cooperation of proto-signals for nuclear accumulation of estrogen and progesterone receptors. EMBO J. 11 (1992) 3681-3694.
39. Picard D., Kumar V., Chambon P. and Yamamoto K. R.: Signal transduction by steroid hormones: nuclear localization is differentially regulated in estrogen and glucocorticoid receptors. Cell Reg. 1 (1990) 291-299.
40. Zhou Z. X., Sar M., Simental J. A., Lane M. V. and Wilson E. M.: A ligand dependent bipartite nuclear targeting signal in the human androgen receptor. J. Biol. Chem. 269 (1994) 13,115-13,123.
41. Guiochon-Mantel A., Lescop P., Christin-Maitre S., Loosfelt H., Perrot-Applanat M. and Milgrom E.: Nucleocytoplasmic shuttling of the progesterone receptor. EMBO J. 10 (1991) 3851-3859.
42. Picard D., Salser S. J. and Yamamoto K. R.: A moveable and regulable inactivation function within the steroid binding domain of the glucocorticoid receptor. Cell 54 (1988) 1073-1080.
43. Urda L. A., Yen P. M., Simons S. S. Jr. and Harmon J. M.: Region-specific antiglucocorticoid receptor antibodies selectively recognize the activated form of the ligand-occupied receptor and inhibit the binding of activated complexes to deoxyribonucleic acid. Molec. Endocr. 3 (1989) 251-256.
44. Borer R. A., Lehner C. F., Eppenberger H. M. and Nigg E.: Major nucleolar proteins shuttle between nucleus and cytoplasm. Cell 56 (1989) 379-390.
45. Meier U. T. and Blobel G.: Nopp 140 shuttles on tracks between nucleolus and cytoplasm. Cell 70 (1992) 127-138.
46. Mandell R. B. and Feldherr C. M.: Identification of two hsp70-related Xenopus oocyte proteins that are capable of recycling across the nuclear envelope. J. Cell. Biol. 111 (1990) 1775-1783.
47. Madan A. P. and DeFranco D. B.: Bidirectional transport of glucocorticoid receptors across the nuclear envelope. Proc. Natn. Acad. Sci. U.S.A. 90 (1993) 3588-3592.
48. Dauvois S., White R. and Parker M. G.: The antiestrogen ICI182780 disrupts estrogen receptor nucleocytoplasmic shuttling. J. Cell Sci. 106 (1993) 1377-1388.
49. Molinari A. M., Medici N., Armetta I., Nigro V., Montcharmont B. and Puca G. A.: Particulate nature of the unoccupied uterine estrogen receptor. Biochem. Biophys. Res. Commun. 128 (1985) 634-642.
50. Liao S., Smythe S., Tymoczko J. L., Rossini G. P., Chen C. and Hiipakka R. A.: RNA-dependent release of androgen and other steroid receptor complexes from DNA. J. Biol. Chem. 255 (1980) 5545-5551.
51. Verdi J. M. and Campagnoni A. T.: Translational regulation by steroids. Identification of steroid modulatory element in the 5′-untranslated region of the myelin basic protein messenger RNA. J. Biol. Chem. 265 (1990) 20,314-20,320.
52. Akner G., Sundqvist K. G., Denis M., Wikström A. C. and Gustafsson J. A.: Immunocytochemical localization of glucocorticoid receptor in human gingival fibroblasts and evidence for a colocalization of glucocorticoid receptor with cytoplasmic microtubules. Eur. J. Cell Biol. 53 (1990) 390-401.
53. Miyata Y. and Yahara I.: Cytoplasmic 8 S glucocorticoid receptor binds to actin filaments through the 90-kDa heat shock protein moiety. J. Biol. Chem. 266 (1991) 8779-8783.
54. Perrot-Applanat M., Lescop P. and Milgrom E.: The cytoskeleton and the cellular traffic of the progesterone receptor. J. Cell. Biol. 119 (1992) 337-348.
55. Guiochon-Mantel A., Delabre K., Lescop P. and Milgrom E.: Nuclear localization signals also mediate the outward movement of proteins from the nucleus. Proc. Natn. Acad. Sci. U.S.A. (1994) 7179-7183.
56. Davis L. I.: Control of nucleocytoplasmic transport. Curr. Op. Cell Biol. 4 (1992) 424-429.
57. Silver P. A.: How proteins enter the nucleus. Cell 64 (1991) 489-497.
58. Schmidt-Zachmann M. S., Dargemont C., Kuhn L. C. and Nigg E. A.: Nuclear export of proteins: the role of nuclear retention. Cell 74 (1993) 493-504.
59. Wen W., Meinkoth J. L., Tsien R. Y. and Taylor S. S.: Identification of a signal for rapid export of proteins from the nucleus. Cell 82 (1995) 463-473.
60. Fischer U., Huber J., Boelens W. C., Mattaj I. W. and Luhrmann R.: The HIV-1 Rev activation domain is a nuclear export signal that accesses an export pathway used by specific cellular RNAs. Cell 82 (1995) 475-183.
61. Moroianu J. and Blobel G.: Protein export from the nucleus requires the GTPase Ran and GTP hydrolysis. Proc. Natn. Acad. Sci. U.S.A. 92 (1995) 4318-4322.
62. Guiochon-Mantel A., Loosfelt H., Ragot T., Bailly A., Atger M., Misrahi M., Perricaudet M. and Milgrom E.: Receptors bound to antiprogestin from abortive complexes with hormone responsive elements. Nature 336 (1988) 695-698.
63. Klein-Hitpass L., Cato A. C. B., Henderson D. and Ryffel G. U.: Two types of antiprogestins identified by their differential action in transcriptionally active extracts from T47D cells. Nucl. Acids Res. 19 (1991) 1227-1234.
64. Delabre K., Guiochon-Mantel A. and Milgrom E.: In vivo evidence against the existence of antiprogestins disrupting receptor binding to DNA. Proc. Natn. Acad. Sci. U.S.A. 90 (1993) 4421-4425.