Animal cell cytokinesis

Annual Review of Cell and Developmental Biology

Volumn 17, Issue , 2001, Pages 351-386

  Glotzer, M ^a  

^a RESEARCH INSTITUTE OF MOLECULAR PATHOLOGY   (Austria)

Author keywords

Cell division; Central spindle; Cleavage furrow; Contractile ring; Rho

Indexed keywords

MYOSIN ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; CELL DIVISION; CELL FUSION; CELL MATURATION; CELL ORGANELLE; CELL STRUCTURE; CENTROSOME; CHROMOSOME; CONFERENCE PAPER; CYTOKINESIS; CYTOSKELETON; DICTYOSTELIUM DISCOIDEUM; MITOSIS SPINDLE; NONHUMAN; PRIORITY JOURNAL;

ACTINS; ANIMALS; CELL DIVISION; CELL MEMBRANE; CENTROSOME; DICTYOSTELIUM; MICROTUBULES; MITOTIC SPINDLE APPARATUS; MYOSINS; RHO GTP-BINDING PROTEINS; SACCHAROMYCETALES; SCHIZOSACCHAROMYCES;

ANIMALIA; DICTYOSTELIUM DISCOIDEUM;

EID: 0035184138     PISSN: 10810706     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.cellbio.17.1.351     Document Type: Conference Paper

References (191)

1. Xenopus laevis actin-depolymerizing factor/cofilin: A phosphorylation- regulated protein essential for development
2. Evidence for functional differentiation among Drosophila septins in cytokinesis and cellularization
3. Pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis
4. INCENP binds the Aurora-related kinase AIRK2 and is required to target it to chromosomes, the central spindle and cleavage furrow
5. Identification of a carboxyterminal diaphanous-related formin homology protein autoregulatory domain
6. Phosphorylation activation of myosin by Rho-associated kinase (Rhokinase)
7. The cytokinesis gene KEULE encodes a Sec 1 protein that binds the syntaxin KNOLLE
8. Role of polo kinase and Mid1p in determining the site of cell division in fission yeast
9. Tying the knot: Linking cytokinesis to the nuclear cycle
10. A mechanism for coupling exit from mitosis to partitioning of the nucleus
11. Multinucleation and inhibition of cytokinesis in suspended cells: Reversal upon reattachment to a substrate
12. Involvement of an actomyosin contractile ring in Saccharomyces cerevisiae cytokinesis
13. New membrane formation during cytokinesis in normal and cytochalasin B-treated eggs of Xenopus laevis. I. Electron microscope observations
14. Spindle self-organization and cytokinesis during male meiosis in asterless mutants of Drosophila melanogaster
15. A phospholipid kinase regulates actin organization and intercellular bridge formation during germline cytokinesis
16. The synaptic protein syntaxin1 is required for cellularization of Drosophila embryos
17. Traction forces of cytokinesis measured with optically modified elastic substrata
18. The role of pre- and post-anaphase microtubules in the cytokinesis phase of the cell cycle
19. Mechanism of the formation of contractile ring in dividing cultured animal cells. I. Recruitment of preexisting actin filaments into the cleavage furrow
20. Signals from the spindle midzone are required for the stimulation of cytokinesis in cultured epithelial cells
21. Drosophila polo kinase is required for cytokinesis
22. Effects of cytochalasins on mammalian cells
23. Diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene
24. Movement of a cytokinesis factor cdc12p to the site of cell division
25. Cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin
26. Cdc42 is required for PIP(2)-induced actin polymerization and early development but not for cell viability
27. Roles of two homotetrameric kinesins in sea urchin embryonic cell division
28. Syntaxin is required for cell division
29. The inner centromere protein (INCENP) antigens: Movement from inner centromere to midbody during mitosis
30. Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice
31. Requirement for microtubules in new membrane formation during cytokinesis of Xenopus embryos
32. Telomerase inhibition and cancer
33. Disruption of the Dictyostelium myosin heavy chain gene by homologous recombination
34. A septin-based hierarchy of proteins required for localized deposition of chitin in the Saccharomyces cerevisiae cell wall
35. Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis
36. A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos
37. Interaction of a Golgi-associated kinesin-like protein with Rab6
38. Chromosomal proteins and cytokinesis: Patterns of cleavage furrow formation and inner centromere protein positioning in mitotic heterokaryons and mid-anaphase cells
39. Redistribution of phosphatidylethanolamine at the cleavage furrow of dividing cells during cytokinesis
40. An essential role for a membrane lipid in cytokinesis. Regulation of contractile ring disassembly by redistribution of phosphatidylethanolamine
41. Bni1p, a yeast formin linking cdc42p and the actin cytoskeleton during polarized morphogenesis
42. Cortexillins, major determinants of cell shape and size, are actinbundling proteins with a parallel coiled-coil tail
43. A purified Drosophila septin complex forms filaments and exhibits GTPase activity
44. Orientation and three-dimensional organization of actin filaments in dividing cultured cells
45. An actin-like component in spermatocytes of a crane fly (Nephrotoma suturalis Loew). II. The cell cortex
46. Caenorhabditis elegans inhibitor of apoptosis protein (lAP) homologue BIR-1 plays a conserved role in cytokinesis
47. Polymerization of purified yeast septins: Evidence that organized filament arrays may not be required for septin function
48. Alpha-actinin localization in the cleavage furrow during cytokinesis
49. Cytokinesis without myosin II
50. Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis
51. Polo kinase: The choreographer of the mitotic stage?
52. Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phosphorylated during cytokinesis
53. Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo
54. The role of the sid1p kinase and cdc 14p in regulating the onset of cytokinesis in fission yeast
55. A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans
56. Immunofluorescence localization of the Saccharomyces cerevisiae CDC 12 gene product to the vicinity of the 10-nm filaments in the mother-bud neck
57. The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity
58. Formin' the connection between microtubules and the cell cortex
59. Dynein-dependent movements of the mitotic spindle in Saccharomyces cerevisiae do not require filamentous actin
60. The Rab6-binding kinesin, Rab6-KIFL, is required for cytokinesis
61. Zygotic expression of the pebble locus is required for cytokinesis during the postblastoderm mitoses of Drosophila
62. MgcRacGAP is involved in cytokinesis through associating with mitotic spindle and midbody
63. Anaphase is initiated by proteolysis rather than by the inactivation of maturation-promoting factor
64. Mitotic phosphorylation of histone H3 is governed by Ip11/aurora kinase and G1c7/PP1 phosphatase in budding yeast and nematodes
65. Centrosome movement in the early divisions of Caenorhabditis elegans: A cortical site determining centrosome position
66. Bni1p and Bnr1p: Downstream targets of the Rho family small G-proteins which interact with profilin and regulate actin cytoskeleton in Saccharomyces cerevisiae
67. Coordination of microtubules and the actin cytoskeleton by the Rho effector mDial
68. Depletion of syntaxins in the early Caenorhabditis elegans embryo reveals a role for membrane fusion events in cytokinesis
69. CYK-4: A Rho family GTPase activating protein (GAP) required for central spindle formation and cytokinesis
70. Long crocidolite asbestos fibers cause polyploidy by sterically blocking cytokinesis
71. Molecular characterization of CDC42, a Saccharomyces cerevisiae gene involved in the development of cell polarity
72. Myosin light chain-activating phosphorylation sites are required for oogenesis in Drosophila
73. Gamma-Tubulin participates in the formation of the midbody during cytokinesis in mammalian cells
74. Byr4, a dosage-dependent regulator of cytokinesis in S. Pombe, interacts with a possible small GTPase pathway including Spg1 and Cdc16
75. Incenp and an aurora-like kinase form a complex essential for chromosome segregation and efficient completion of cytokinesis
76. Interaction of Bnr1p with a novel Src homology 3 domain-containing Hof1 p. Implication in cytokinesis in Saccharomyces cerevisiae
77. Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: Role of iron-catalyzed free radicals
78. The regulatory light chain of nonmuscle myosin is encoded by spaghetti-squash, a gene required for cytokinesis in Drosophila
79. Phosphorylation of myosin-binding subunit (MBS) of myosin phosphatase by rho-kinase in vivo
80. Down-regulation of an AIM-1 kinase couples with megakaryocytic polyploidization of human hematopoietic cells
81. Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression
82. Cellular morphogenesis in the Saccharomyces cerevisiae cell cycle: Localization of the CDC3 gene product and the timing of events at the budding site
83. S1i15 associates with the ip11 protein kinase to promote proper chromosome segregation in Saccharomyces cerevisiae
84. Accumulation of GTP-bound RhoA during cytokinesis and a critical role of ECT2 in this accumulation
85. Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI)
86. Antisense RNA inactivation of myosin heavy chain gene expression in Dictyostelium discoideum
87. Effects of the regulatory light chain phosphorylation of myosin II on mitosis and cytokinesis of mammalian cells
88. Cyk3, a novel SH3-domain protein, affects cytokinesis in yeast
89. Phosphorylation of glial fibrillary acidic protein at the same sites by cleavage furrow kinase and Rho-associated kinase
90. Specific accumulation of Rho-associated kinase at the cleavage furrow during cytokinesis: Cleavage furrow-specific phosphorylation of intermediate filaments
91. Rhokinase/ROCK is involved in cytokinesis through the phosphorylation of myosin light chain and not ezrin/radixin/moesin proteins at the cleavage furrow
92. Human hepatocyte polyploidization kinetics in the course of life cycle
93. Heterogeneity and microtubule interaction of the CHO1 antigen, a mitosis-specific kinesin-like protein. Analysis of subdomains expressed in insect sf9 cells
94. Characterization of the p53-dependent postmitotic checkpoint following spindle disruption
95. Controlling septation in fission yeast: Finding the middle, and timing it right
96. Analysis of the cps1 gene provides evidence for a septation checkpoint in Schizosaccharomyces pombe
97. Plk is an M-phase-specific protein kinase and interacts with a kinesin- like protein, CHO1/MKLP-1. Mol
98. The pebble gene is required for cytokinesis in Drosophila
99. Formation of binucleated cardiac myocytes in rat heart: I. Role of actin-myosin contractile ring
100. A checkpoint that monitors cytokinesis in Schizosaccharomyces pombe
101. Drc1p/Cps1p, a 1,3-betaglucan synthase subunit, is essential for division septum assembly in Schizosaccharomyces pombe
102. The septins: Roles in cytokinesis and other processes
103. Cytokinesis in the ArabMopsis embryo involves the syntaxin-related KNOLLE gene product
104. A rholike protein is involved in the organisation of the contractile ring in dividing sand dollar eggs
105. The effect of myosin antibody on the division of starfish blastomeres
106. Centrosome repositioning immediately following karyokinesis and prior to cytokinesis
107. Role of citron kinase as a target of the small GTPase Rho in cytokinesis
108. Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
109. Delay of HeLa cell cleavage into interphase using dihydrocytochalasin B: Retention of a postmitotic spindle and telophase disc correlates with synchronous cleavage recovery
110. Colocalization of TD-60 and INCENP throughout G2 and mitosis: Evidence for their possible interaction in signalling cytokinesis
111. Interpolar spindle microtubules in PTK cells
112. Specific localization of serine 19 phosphorylated myosin II during cell locomotion and mitosis of cultured cells
113. Zygotic development without functional mitotic centrosomes
114. Oncogene ect2 is related to regulators of small GTP-binding proteins
115. The cortical localization of the microtubule orientation protein, Kar9p, is dependent upon actin and proteins required for polarization
116. Phosphorylation of Ser-3 of cofilin regulates its essential function on actin
117. Thrombopoietin-induced polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis
118. Evidence for F-actin-dependent and -independent mechanisms involved in assembly and stability of the medial actomyosin ring in fission yeast
119. The Drosophila peanut gene is required for cytokinesis and encodes a protein similar to yeast putative bud neck filament proteins
120. Microtubule-mediated centrosome motility and the positioning of cleavage furrows in multinucleate myosin II-null cells
121. Myosin H-independent processes in mitotic cells of Dictyostelium discoideum: Redistribution of the nuclei, re-arrangement of the actin system and formation of the cleavage furrow
122. The C. Elegans septin genes, unc-59 and unc-61, are required for normal postem-bryonic cytokineses and morphogenesis but have no essential function in embryogenesis
123. Polo-like kinases: Positive regulators of cell division from start to finish
124. A plus-end-directed motor enzyme that moves antiparallel microtubules in vitro localizes to the interzone of mitotic spindles
125. A monoclonal antibody to a mitotic microtubule-associated protein blocks mitotic progression
126. Fibronectin mediates cytokinesis and growth of rat follicular cells in serum-free medium
127. The Bub2p spindle checkpoint links nuclear migration with mitotic exit
128. Actin-like filaments in the cleavage furrow of newt egg
129. Embryonic morphogenesis in Caenorhabditis elegans integrates the activity of LET-502 Rho-binding kinase, MEL-11 myosin phosphatase, DAF- 2 insulin receptor and FEM-2 PP2c phosphatase
130. Centrosome-dependent exit of cytokinesis in animal cells
131. A nematode kinesin required for cleavage furrow advancement
132. A putative exchange factor for Rhol GTPase is required for initiation of cytokinesis in Drosophila
133. Cytokinesis and midzone microtubule organization in Caenorhabditis elegans require the kinesin-like protein ZEN-4
134. Experiments concerning the cleavage stimulus in sand dollar eggs
135. Cleavage furrow establishment by the moving mitotic apparatus
136. Cytokinesis: Effects of blocks between the mitotic apparatus and the surface on furrow establishment in flattened echinoderm eggs
137. CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans
138. Mitosis in vertebrate somatic cells with two spindles: Implications for the metaphase/anaphase transition checkpoint and cleavage
139. The establishment of polarized membrane traffic in Xenopus laevis embryos
140. Formation of the Drosophila ovarian ring canal inner rim depends on cheerio
141. Dynacortin, a genetic link between equatorial contractility and global shape control discovered by library complementation of a Dictyostelium discoideum cytokinesis mutant
142. Yeast myosin heavy chain mutant: Maintenance of the cell-type-specific budding pattern and the normal deposition of chitin and cell wall components requires an intact myosin heavy chain gene
143. Phosphorylation of myosin-II regulatory light chain by cyclin-p34cdc2: A mechanism for the timing of cytokinesis
144. Electron microscopic and time lapse studies of mitosis in cultured rat hepatocytes
145. Interzone microtubule behavior in late anaphase and telophase spindles
146. Role of the zygotic genome in the restructuring of the actin cytoskeleton at the cycle-14 transition during Drosophila embryogenesis
147. The Spg1p GTPase is an essential, dosage-dependent inducer of septum formation in Schizosaccharomyces pombe
148. Cytokinesis: Filaments in the cleavage furrow
149. Actin in dividing cells: Contractile ring filaments bind heavy meromyosin
150. AIR-2: An aurora/Ip11-related protein kinase associated with chromosomes and midbody microtubules is required for polar body extrusion and cytokinesis in Caenorhabditis elegans embryos
151. The aurora-related kinase AIR-2 recruits ZEN-4/CeMKLP1 to the mitotic spindle at metaphase and is required for cytokinesis
152. The nonmuscle myosin regulatory light chain gene mlc-4 is required for cytokinesis, anterior-posterior polarity, and body morphology during Caenorhabditis elegans embryogenesis
153. Exit from mitosis is triggered by Tem1-dependent release of the protein phosphatase Cdc14 from nucleolar RENT complex
154. A transient association of gamma-tubulin at the midbody is required for the completion of cytokinesis during the mammalian cell division
155. Parameters that specify the timing of cytokinesis
156. Lava lamp, a novel peripheral Golgi protein, is required for Drosophila melanogaster cellularization
157. The completion of cytokinesis in C. Elegans blastomeres requires a brefeldin A-sensitive process and involves the accumulation of membrane at the apex of the cleavage furrow
158. Human survivin is a kinetochore-associated passenger protein
159. Divide and conquer: Cytokinesis in plant cells
160. The dmf1/mid1 gene is essential for correct positioning of the division septurn in fission yeast
161. The survivin-like C. Elegans BIR-1 protein acts with the Aurora-like kinase AIR-2 to affect chromosomes and the spindle midzone
162. Rac1 is required for the formation of three germ layers during gastrulation
163. Cofilin phosphorylation and actin cytoskeletal dynamics regulated by rho- and Cdc42-activated LIM-kinase 2
164. C. Elegans FH gene required for a late step in embryonic cytokinesis
165. Human ECT2 is an exchange factor for Rho GTPases, phosphorylated in G2/M phases, and involved in cytokinesis
166. The role of actin in spindle orientation changes during the Saccharomyces cerevisiae cell cycle
167. Macrophage myosin. Regulation of actin-activated AT-Pase, activity by phosphorylation of the 20,000-dalton light chain
168. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype
169. Roles of Hof1p, Bni1p, Bnr1p, and myo1p in cytokinesis in Saccharomyces cerevisiae
170. The phosphatase Cdc14 triggers mitotic exit by reversal of Cdk- dependent phosphorylation
171. Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphase
172. The Bfa1/ Bub2 GAP complex comprises a universal checkpoint required to prevent mitotic exit
173. FH proteins as cytoskeletal organizers
174. Cooperation between mDial and ROCK in Rho-induced actin reorganization
175. The yeast MYO1 gene encoding a myosin-like protein require for cell division
176. Cytokinesis mediated through the recruitment of cortexillins into the cleavage furrow
177. The world according to Arp: Regulation of actin nucleation by the Arp2/3 complex
178. CDK1 inactivation regulates anaphase spindle dynamics and cytokinesis in vivo
179. INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow
180. Midzone microtubule bundles are continuously required for cytokinesis in cultured epithelial cells
181. Cell proliferation in the ectoderm of the Xenopus embryo: Development of substratum requirements for cytokinesis
182. Caenorhabditis elegans LET-502 is related to Rho-binding kinases and human myotonic dystrophy kinase and interacts genetically with a homolog of the regulatory subunit of smooth muscle myosin phosphatase to affect cell shape
183. Kelch encodes a component of intercellular bridges in Drosophila egg chambers
184. In vivo phosphorylation of regulatory light chain of myosin II during mitosis of cultured cells
185. Roles of Rho-associated kinase in cytokinesis; Mutations in Rho-associated kinase phosphorylation sites impair cytokinetic segregation of glial filaments
186. Dynamic positioning of mitotic spindles in yeast: Role of microtubule motors and cortical determinants
187. Morphogenesis in Drosophila requires nonmuscle myosin heavy chain function
188. Hu-li tai shao, a gene required for ring canal formation during Drosophila oogenesis, encodes a homolog of adducin
189. On the role of myosin-II in cytokinesis: Division of Dictyostelium cells under adhesive and nonadhesive conditions
190. Control of the yeast bud-site assembly GTPase Cdc42. Catalysis of guanine nucleotide exchange by Cdc24 and stimulation of GTPase activity by Bem3