The Aspergillus nidulans sepA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity

EMBO Journal

Volumn 16, Issue 12, 1997, Pages 3474-3483

  Harris, Steven D ^a   Hamer, Lisbeth ^b   Sharpless, Kathryn E ^a   Hamer, John E ^b  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^b PURDUE UNIVERSITY   (United States)

Author keywords

2 Protein; Aspergillus; Cellular polarity; Cytokinesis; FH1; Septation

Indexed keywords

ACTIN; FUNGAL PROTEIN;

ARTICLE; ASPERGILLUS NIDULANS; CELL DIVISION; CELL GROWTH; CONTROLLED STUDY; CYTOKINESIS; CYTOSKELETON; DELETION MUTANT; DROSOPHILA; GENE MUTATION; IMMUNOFLUORESCENCE MICROSCOPY; MITOSIS; MOLECULAR CLONING; MORPHOGENESIS; NONHUMAN; PRIORITY JOURNAL; TEMPERATURE SENSITIVITY;

ALLELES; AMINO ACID SEQUENCE; ASPERGILLUS NIDULANS; BASE SEQUENCE; CELL DIVISION; CELL POLARITY; CLONING, MOLECULAR; DNA, FUNGAL; FUNGAL PROTEINS; GENE DELETION; GENES, DOMINANT; MITOSIS; MOLECULAR SEQUENCE DATA; TEMPERATURE;

ASPERGILLUS; EMERICELLA NIDULANS; FUNGI;

EID: 0030927282     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.12.3474     Document Type: Article

References (54)

1. Adams, A.E.M. and Pringle, J.R. (1984) Relationship of actin and tubulin distribution to bud growth in wild-type and morphogenetic mutant Saccharomyces cerevisiae. J. Cell Biol., 98, 934-945.
2. Balasubramanian, M.K., Helfman, D.M. and Hemmingsen, S.M. (1992) A new tropomyosin essential for cytokinesis in the fission yeast S. pombe. Nature, 360, 84-87.
3. + gene encodes a profilin essential for cytokinesis. J. Cell. Biol., 125, 1289-1301.
4. Bassett, D.E., Boguski, M., Spencer, F., Reeves, R., Goebl, M. and Hieter, P. (1995) Comparative genomics, genome cross-referencing and XREFdb. Trends Genet., 11, 372-373.
5. Berger, B., Wilson, D.B., Wolf, E., Tonchev, T., Milla, M. and Kim, P.S. (1995) Predicting coiled coils by use of pairwise residue correlations. Proc. Natl Acad. Sci. USA, 92, 8259-8263.
6. Brody, H., Griffith, J., Cuticchia, A.J., Arnold, J. and Timberlake, W.E. (1991) Chromosome-specific recombinant DNA libraries from the fungus Aspergillus nidulans. Nucleic Acids Res., 19, 3109-3109.
7. Castrillon, D.H. and Wasserman, S.A. (1994) diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the the products of the limb deformity gene. Development, 120, 3367-3377.
8. Chan, D.C., Bedford, M.T. and Leder, P. (1996) Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J., 15, 1045-1054.
9. Chang, F., Woollard, A. and Nurse, P. (1996) Isolation and characterization of fission yeast mutants defective in the assembly and placement of the contractile actin ring. J. Cell Sci., 109, 131-142.
10. Chang, F., Drubin, D. and Nurse, P. (1997) cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin. J. Cell Biol., 137, 169-182.
11. Chant, J. and Stowers, L. (1995) GTPase cascades choreographing cellular behavior: movement, morphogenesis, and more. Cell, 81, 1-4.
12. Clutterbuck, A.J. (1987) Aspergillus nidulans. In O'Brien, S.J. (ed.), Genetic Maps. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, Vol. 4, pp. 325-335.
13. Dobinson, K.F., Harris, R. and Hamer, J.E. (1993) Grasshopper: a retrotransposon of Magnaporthe grisea. Mol. Plant Microbiol. Interact., 6, 114-126.
14. Emmons, S., Phan, H., Calley, J., Chen, W., James, B. and Manseau, L. (1995) cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus. Genes Dev., 9, 2482-2494.
15. Evangelista, M., Blundell, K., Longtine, M.S., Chow, C.J., Adames, N., Pringle, J.R., Peter, M. and Boone, C. (1997) Bni1p, a yeast formin linking Cdc42p and the actin cytoskeleton during polarized morphogenesis. Science, 276, 118-122.
16. Field, C.M., and Alberts, B.M. (1995) Anillin, a contractile ring protein that cycles from the nucleus to the cell cortex. J. Cell Biol., 131, 165-178.
17. Fishkind, D.J. and Wang, Y. (1995) New horizons for cytokinesis. Curr. Opin. Cell Biol., 7, 23-31.
18. Gems, D., Johnstone, I.L. and Clutterbuck, A.J. (1991) An autonomously replicating plasmid transforms Aspergillus nidulans at high frequency. Gene, 98, 61-67.
19. Gow, N.A.R. (1995) Tip growth and polarity. In Gow, N.A.R. and Gadd, G.M. (eds), The Growing Fungus. Chapman and Hall, London, UK, pp. 277-299.
20. Harris, S.D. and Hamer, J.E. (1995) sepB: an Aspergillus nidulans gene involved in chromosome segregation and the initiation of cytokinesis. EMBO J., 14, 5244-5257.
21. Harris, S.D., Morrell, J.L. and Hamer, J.E. (1994) Identification and characterization of Aspergillus nidulans mutants defective in cytokinesis. Genetics, 136, 517-532.
22. Hoch, H.C. and Howard, R.J. (1980) Ultrastructure of freeze-substituted hyphae of the basidiomycete Laetisaria arvalis. Protoplasma, 103, 281-297.
23. Janmey, P.A. (1991) Polyproline affinity method for purification of platelet profilin and modification with pyrene-maleimide. Methods Enzymol., 196, 92-99.
24. Jansen, R.-P., Dowzer, C., Michaelis, C., Galova, M. and Nasmyth, K. (1996) Mother cell-specific HO expression in budding yeast depends on the unconventional myosin Myo4p and other cytoplasmic proteins. Cell, 84, 687-697.
25. Kafer, E. (1977) Meiotic and mitotic recombination in Aspergillus nidulans and its chromosomal aberrations. Adv. Genet., 19, 33-131.
26. Kilmartin, J.V. and Adams, A.E.M. (1984) Structural rearrangements of tubulin and actin during the cell cycle of the yeast Saccharomyces cerevisiae. J. Cell Biol., 98, 922-933.
27. Kishi, K., Sasaki, T., Kuroda, S., Itoh, T. and Takai, Y. (1993) Regulation of cytoplasmic division of Xenopus embryo by rho p21 and its inhibitory GDP/GTP exchange protein (rho GDI). J. Cell Biol., 120, 1187-1195.
28. Larochelle, D.A., Vithalani, K.K. and De Lozanne, A. (1996) A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis. J. Cell Biol., 133, 1321-1329.
29. Longtine, M.S., DeMarini, D., Valencik, M., Al-Awar, O.S., Fares, H., De Virglio, C. and Pringle, J.R. (1996) The septins: roles in cytokinesis and other processes. Curr. Opin. Cell Biol., 8, 106-119.
30. Lupas, A., van Dyke, M. and Stock, J. (1991) Predicting coiled coils from protein sequences. Science, 252, 1162-1164.
31. Mabuchi, I., Hamaguchi, Y., Fujimoto, H., Morii, N., Mishima, M. and Narumiya, S. (1993) A rho-like protein is involved in the organization of the contractile ring in dividing sand dollar eggs. Zygote, 1, 325-331.
32. Manseau, L., Calley, J. and Phan, H. (1996) Profilin is required for posterior patterning of the Drosophila oocyte. Development, 122, 21090-2116.
33. Marhoul, J.F. and Adams, T.H. (1995) Identification of developmental regulatory genes in Aspergillus nidulans by overexpression. Genetics, 139, 537-547.
34. Marks, J. and Hyams, J.S. (1985) Localization of F-actin through the cell division cycle of S. pombe. Eur. J. Cell Biol., 39, 27-32.
35. + gene encodes a novel EF-hand protein essential for cytokinesis. J. Cell Biol., 130, 651-660.
36. Momany, M., Morrell, J.M., Harris, S.D. and Hamer, J.E. (1995) Septum formation in Aspergillus nidulans. Can. J. Bot., 73, S369-S399.
37. Morris, N.R. (1976) Mitotic mutants of Aspergillus nidulans. Genet. Res., 26, 237-254.
38. Mulholland, J., Preuss, D., Moon, A., Wong, A., Drubin, D. and Botstein, D. (1994) Ultrastructure of the yeast actin cytoskeleton and its association with the plasma membrane. J. Cell Biol., 125, 381-391.
39. Oakley, B.R. and Osmani, S.A. (1993) Cell-cycle analysis using the filamentous fungus Aspergillus nidulans. In Fantes, P. and Brooks, R. (eds), The Cell Cycle: A Practical Approach. Oxford University Press, Oxford, UK, pp. 127-142.
40. Pantaloni, D. and Carlier, M.-F. (1993) How profilin promotes actin filament assembly in the presence of thymosin β4. Cell, 75, 1007-1014.
41. Pawson, T. (1995) Protein modules and signalling networks. Nature, 373, 573-580.
42. Petersen, J., Weilguny, D., Egel, R. and Nielsen, O. (1995) Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation. Mol. Cell. Biol., 15, 3697-3707.
43. Rappaport, R. (1986) Establishment of the mechanism of cytokinesis in animal cells. Int. Rev. Cytol., 105, 245-281.
44. Raudaskoski, M. (1970) Occurrence of microtubules and microfilaments, and origin of septa in dikaryotic hyphae of Schizophyllum commune. Protoplasma, 70, 415-422.
45. Ridley, A.J. (1996) Rho: theme and variations. Curr. Biol., 6, 1256-1264.
46. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning: A Laboratory Manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
47. Sato, N., Yonemura, S., Obinata, T., Tsukita, S. and Tsukita, S. (1991) Radixin, a barbed end capping actin modulating protein is concentrated at the cleavage furrow during cytokinesis. J. Cell Biol., 113, 321-330.
48. Satterwhite, L.L. and Pollard, T.D. (1992) Cytokinesis. Curr. Opin. Cell Biol., 4, 43-52.
49. Sudol, M. (1996) The WW module competes with the SH3 domain? Trends Biochem. Sci., 21, 161-163.
50. Timberlake, W.E. (1980) Developmental gene regulation in Aspergillus nidulans. Dev. Biol., 78, 497-510.
51. Timberlake, W.E. (1991) Temporal and spatial controls of Aspergillus development. Curr. Opin. Genet. Dev., 1, 351-357.
52. Trinci, A.P.J. and Morris, N.R. (1979) Morphology and growth of a temperature-sensitive mutant of Aspergillus nidulans which forms aseptate mycelia at non-permissive temperatures. J. Gen. Microbiol., 114, 53-59.
53. Woychik, R.P., Maas, R.L., Zeller, R., Vogt, T.F. and Leder, P. (1990) 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene. Nature, 346, 850-853.
54. Zahner, J.E., Harkins, H.A. and Pringle, J.R. (1996) Genetic analysis of bipolar bud site selection in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol., 16, 1857-1870.