cdc12p, a protein required for cytokinesis in fission yeast, is a component of the cell division ring and interacts with profilin

Journal of Cell Biology

Volumn 137, Issue 1, 1997, Pages 169-182

  Chang, Fred ^a,b,c   Drubin, David ^b   Nurse, Paul ^a  

^a IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELL DIVISION; DROSOPHILA; GENE MUTATION; GENETIC ANALYSIS; MOLECULAR CLONING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; SACCHAROMYCES CEREVISIAE; SCHIZOSACCHAROMYCES POMBE; YEAST;

ACTINS; BASE SEQUENCE; CELL CYCLE PROTEINS; CELL DIVISION; CLONING, MOLECULAR; CONTRACTILE PROTEINS; CYTOSKELETAL PROTEINS; FUNGAL PROTEINS; GENE EXPRESSION REGULATION, FUNGAL; MICROFILAMENT PROTEINS; MITOSIS; MOLECULAR SEQUENCE DATA; MUTATION; PHENOTYPE; PROFILINS; SACCHAROMYCES CEREVISIAE PROTEINS; SCHIZOSACCHAROMYCES; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0030958087     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.137.1.169     Document Type: Article

References (65)

1. Balasubramanian, M.K., D.M. Helfman, and S.M. Hemmingsen. 1992. A new tropomyosin essential for cytokinesis in the fission yeast S. pombe. Nature (Lond.). 360:84-87.
2. Balasubramanian, M.K., B.R. Hirani, J.D. Burke, and K.L. Gould. 1994. The Schizosaccharomyces pombe cdc3+ gene encodes a profilin essential for cytokinesis. J. Cell Biol. 125:1289-1301.
3. Barbet, N., W.J. Muriel, and A.M. Carr. 1992. Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe. Gene (Amst.). 114: 59-66.
4. Bobola, N., R.P. Jansen, T.H. Shin, and K. Nasmyth. 1996. Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells. Cell. 84:699-709.
5. Castrillon, D.H., and S.A. Wasserman. 1994. diaphanous is required for cytokinesis in Drosophila and shares domains of similarity with the products of the limb deformity gene. Development (Camb.). 120:3367-3377.
6. Chakraborty, T., F. Ebel, E. Domann, K. Niebuhr, B. Gerstel, S. Pistor, C.J. Temm-Grove, B.M. Jockusch, M. Reinhard, and U. Walter. 1995. A focal adhesion factor directly linking intracellularly motile Listeria monocytogenes and Listeria ivanovii to the actin-based cytoskeleton of mammalian cells. EMBO (Eur. Mol. Biol. Organ.) J. 14:1314-1321.
7. Chang, F., and P. Nurse. 1996. How fission yeast fission in the middle. Cell. 84: 191-194.
8. Chang, F., A. Woollard, and P. Nurse. 1996. Identification and characterization of fission yeast mutants defective in actin ring assembly and placement. J. Cell Sci. 109:131-142.
9. Conrad, G.W., and T.E. Schroeder, editors. 1990. Cytokinesis: Mechanisms of Furrow Formation During Cell Division. New York Academy of Sciences, New York.
10. Correa-Bordes, J., and P. Nurse. 1995. p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase. Cell. 83:1001-1009.
11. Elledge, S., J. Mulligan, S. Ramer, M. Spottswood, and R. Davis. 1991. λYES: a multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations. Proc. Natl. Acad. Sci. USA. 88:1731-1735.
12. Emmons, S., H. Phan, J. Calley, W. Chen, B. James, and L. Manseau. 1995. cappuccino, a Drosophila maternal effect gene required for polarity of the egg and embryo, is related to the vertebrate limb deformity locus. Genes & Dev. 9:2482-2494.
13. Erdelyi, M., A.M. Michon, A. Guichet, J.B. Glotzer, and A. Ephrussi. 1995. Requirement for Drosophila cytoplasmic tropomyosin in oskar mRNA localization. Nature (Lond.). 377:524-527.
14. Evangelista, M., K. Blundell, M.S. Longtine, C.J. Chow, N. Adame, J.R. Pringle, M. Peter, and C. Boone. 1997. Bni1p, a yeast form in linking Cdc42p and the actin cytoskeleton during polarized morphogenesis. Science (Wash. DC). In press.
15. Fankhauser, C., and V. Simanis. 1994. Cold fission: splitting the pombe cell at room temperature. Trends Cell Biol. 4:96-101.
16. Fankhauser, C., A. Reymond, L. Cerutti, S. Utzig, K. Hofmann, and V. Simanis. 1995. The S. pombe cdc15 gene is a key element in the reorganization of F-actin at mitosis. Cell. 82:435-444.
17. Fishkind, D.J., and Y.L. Wang. 1995. New horizons for cytokinesis. Curr Opin. Cell Biol. 7:23-31.
18. Gertler, F.B., K. Niebulr, M. Reinhard, J. Wehland, and P. Soriano. 1996. Mena, a relative of VAST and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell. 87:227-239.
19. Harlow, E., and D. Lane. 1988. Antibodies: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 726 pp.
20. Harris, S.D., L. Hamer, K.E. Sharpless, and J.E. Hamer. 1997. The Aspergillus nidulans scpA gene encodes an FH1/2 protein involved in cytokinesis and the maintenance of cellular polarity. EMBO (Eur. Mol. Biol. Organ.) J. In press.
21. + that encodes a nuclear scaffold-like protein blocks spindle elongation in mitotic anaphase. J. Cell Biol. 106:1171-1183.
22. Hoheisel, J.D., E. Maier, R. Mott, L. McCarthy, A.V. Grigoriev, L.C. Schalkwyk, D. Nizetic, F. Francis, and H. Lehrach. 1993. High resolution cosmid and P1 maps spanning the 14 Mb genome of the fission yeast Schizosaccharomyces pombe. Cell. 73:109-120.
23. Horvitz, H.R., and I. Herskowitz. 1992. Mechanisms of asymmetric cell division: two Bs or not two Bs, that is the question. Cell. 68:237-255.
24. Jochova, J., I. Rupes, and E. Streiblova. 1991. F-actin contractile rings in protoplasts of the yeast Schizosaccharomyces. Cell Biol. Int. Rep. 15:607-610.
25. Kanbe, T., I. Kobayashi, and K. Tanaka. 1989. Dynamics of cytoplasmic organelles in the cell cycle of the fission yeast Schizosaccharomyces pombe: three-dimensional reconstruction from serial sections. J. Cell Sci. 94:647-656.
26. Kelly, T.J., G.S. Martin, S.L. Forsburg, R.J. Stephen, A. Russo, and P. Nurse. 1993. The fission yeast cdc18+ gene product couples S-phase to START and mitosis. Cell. 74:371-382.
27. Kohno, H., K. Tanaka, A. Mino, M. Umikawa, H. Imamura, T. Fujiwara, Y. Fujita, K. Hotta, H. Qadota, Y. Watanabe, et al. 1996. Bni1p implicated in cytoskeletal control is a putative target of Rho1p small GTP binding protein in Saccharomyces cerevisiae. EMBO (Eur. Mol. Biol. Organ.) J. 15:6060-6068.
28. Leupold, U. 1970. Genetic methods for Schizosaccharomyces pombe. Methods Cell Physiol. 4:169-177.
29. Lupas, A., M. Van Dyke, and J. Stock. 1991. Predicting coiled coils from protein sequences. Science (Wash. DC). 252:1162-1164.
30. Maas, R.L., L.I. Jepeal, S.L. Elfering, R.F. Holcombe, C.C. Morton, R.L. Eddy, M.G. Byers, T.B. Shows, and P. Leder. 1991. A human gene homologous to the formin gene residing at the murine limb deformity locus: chromosomal location and RFLPs. Am. J. Hum. Genet. 48:687-695.
31. Machesky, L.M., and T.D. Pollard. 1993. Profilin as a potential mediator of membrane-cytoskeleton communication. Trends Cell Biol. 3:381-385.
32. Machesky, L.M., S.J. Atkinson, C. Ampe, J. Vandekerckhove, and T.D. Pollard. 1994. Purification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agarose. J. Cell Biol. 127:107-115.
33. Maniatis, T., E. Fritsch, and J. Sambrook. 1982. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY. 545 pp.
34. Manseau, L., J. Calley, and H. Phan. 1996. Profilin is required for posterior patterning of the Drosophila oocyte. Development (Camb.). 122:2109-2116.
35. Marks, J., and J.S. Hyams. 1985. Localization of F-actin through the cell division cycle of Schizosaccharomyces pombe. Eur. J. Cell Biol. 39:27-32.
36. Marks, J., I.M. Hagan, and J.S. Hyams. 1987. Spatial association of F-actin with growth polarity and septation in the fission yeast Schizosaccharomyces pombe. In Spatial Organization in Eukaryotic Microbes, R.K. Poole and A.P.C. Trinci, editors. IRL Press, Oxford. 119-135.
37. Mayer, B.J., and M.J. Ekd. 1995. Minding your p's and q's. Curr. Biol. 5:364-367.
38. McCollum, D., M. Balasubramanian, and K. Gould. 1995. Schizosaccharomyces pombe cdc4+ gene encodes a novel EF-hand protein essential for cytokine-sis. J. Cell Biol. 130:651-660.
39. Moreno, S., A. Klar, and P. Nurse. 1991. Molecular genetic analysis of fission yeast Schizosaccharomyces pombe. Methods Enzymol. 194:795-823.
40. Nurse, P., P. Thuriaux, and K. Nasmyth. 1976. Genetic control of the cell division cycle in the fission yeast Schizosaccharomyces pombe. Mol. Gen. Genet. 146:167-178.
41. Ohkura, H., I.M. Hagan, and D.M. Glover. 1995. The conserved Schizosaccharomyces pombe kinase plo1, required to form a bipolar spindle, the actin ring, and septum, can drive septum formation in G1 and G2 cells. Genes & Dev. 9:1059-1073.
42. Pantaloni, D., and M.F. Carlier. 1993. How profilin promotes actin filament assembly in the presence of thymosin beta 4. Cell. 75:1007-1014.
43. Perelroizen, I., J.B. Marchand, L. Blanchoin, D. Didry, and M.F. Carlier. 1994. Interaction of profilin with G-actin and poly (L-proline). Biochemistry. 33: 8472-8478.
44. Petersen, J., D. Weilguny, R. Egel, and O. Nielsen. 1995. Characterization of fus1 of Schizosaccharomyces pombe: a developmentally controlled function needed for conjugation. Mol. Cell. Biol. 15:3697-3707.
45. Pfeffer, S., D. Drubin, and R. Kelly. 1983. Identification of three coated vesicle components as α- and β-tubulin linked to a phosphorylated 50,000-dalton polypeptide. J. Cell Biol. 97:40-47.
46. Pollard, T.D. 1995. Actin cytoskeleton. Missing link for intracellular bacterial motility? Curr. Biol. 5:837-840.
47. Rappaport, R. 1986. Establishment of the mechanism of cytokinesis in animal cells. Int. Rev. Cytol. 101:245-281.
48. Reinhard, M., M. Halbrugge, U. Scheer, C. Wiegand, B.M. Jockusch, and U. Walter. 1992. The 46/50 kDa phosphoprotein VASP purified from human platelets is a novel protein associated with actin filaments and focal contacts. EMBO (Eur. Mol. Biol. Organ.) J. 11:2063-2070.
49. Reinhard, M., K. Giehl, K. Abel, C. Haffner, T. Jarchau, V. Hoppe, B.M. Jockusch, and U. Walter. 1995. The proline-rich focal adhesion and microfilament protein VASP is a ligand for profilins. EMBO (Eur. Mol. Biol. Organ.) J. 14:1583-1589.
50. Rhyu, M.S., and J.A. Knoblich. 1995. Spindle orientation and asymmetric cell fate. Cell. 82:523-526.
51. Roth, S., F. Neuman-Silberberg, G. Barcelo, and T. Schupbach. 1995. cornichon and the EGF receptor signaling process are necessary for both anterior-posterior and dorsal-ventral pattern formation in Drosophila. Cell. 81:967-978.
52. Satterwhite, L.L., and T.D. Pollard. 1992. Cytokinesis. Curr. Opin. Cell Biol. 4: 43-52.
53. Snell, V., and P. Nurse. 1994. Genetic analysis of cell morphogenesis in fission yeast: a role for casein kinase II in the establishment of polarized growth. EMBO (Eur. Mol. Biol. Organ.) J. 13:2066-2074.
54. Sohrmann, M., C. Fankhauser, C. Brodbeck, and V. Simanis. 1996. The dmf1/ mid1 gene is essential for correct positioning of the division septum in fission yeast. Genes & Dev. 10:2707-2719.
55. Streiblova, E., J. Hasek, and E. Jelke. 1984. Septum pattern in ts mutants of Schizosaccharomyces pombe defective in gene cdc3, cdc4, cdc8, and cdc12. J. Cell Sci. 69:47-65.
56. Tanaka, M., and H. Shibata. 1985. Poly (L-proline)-binding proteins from chick embryos are a profilin and a profilactin. Eur. J. Biochem. 151:291-297.
57. Theriot, J.A., and T.J. Mitchison. 1993. The three faces of profilin. Cell. 75:835-838.
58. Theriot, J.A., J. Rosenblatt, D.A. Portnoy, P.J. Goldschmidt-Clermont, and T.J. Mitchison. 1994. Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts. Cell. 76:505-517.
59. Tilney, L.G., E.M. Bonder, L.M. Coluccio, and M.S. Mooseker. 1983. Actin from Thyone sperm assembles on only one end of an actin filament: a behavior regulated by profilin. J. Cell Biol. 97:112-124.
60. Trumpp, A., P.A. Blundell, J.L. de la Pompa, and R. Zeller. 1992. The chicken limb deformity gene encodes nuclear proteins expressed in specific cell types during morphogenesis. Genes & Dev. 6:14-28.
61. Verde, F., J. Mata, and P. Nurse. 1995. Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle. J. Cell Biol. 131:1529-1538.
62. Woods, A., T. Sherwin, R. Sasse, T. MacRae, A. Baines, and K. Gull. 1989. Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies. J. Cell Sci. 93:591-600.
63. Woychik, R.P., R. Maas, R. Zeller, T. Vogt, and P. Leder. 1990. 'Formins': proteins deduced from the alternative transcripts of the limb deformity gene. Nature (Lond.). 346:850-852.
64. Yang, S., K.R. Ayscough, and D.G. Drubin. 1997. A role for the actin cytoskeleton of Saccharomyces cerevisiae in bipolar bud-site selection. J. Cell Biol. 136:111-123.
65. Zahner, J.E., H.A. Harkins, and J.R. Pringle. 1996. Genetic analysis of the bipolar pattern of bud site selection in the yeast Saccharomyces cerevisiae. Mol. Cell. Biol. 16:1857-1870.