S 14506: Novel receptor coupling at 5-HT1A receptors

Neuropharmacology

Volumn 40, Issue 3, 2001, Pages 334-344

  Milligan, Graeme ^a   Kellett, Elaine ^a   Dacquet, Catherine ^b   Dubreuil, Valérie ^b   Jacoby, Edgar ^b,d   Millan, Mark J ^a   Lavielle, Gilbert ^b   Speeding, Michael ^b,c  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b INSTITUT DE RECHERCHES SERVIER   (France)

^c INSTITUT DE RECHERCHES INTERNATIONALES SERVIER   (France)

^d NOVARTIS PHARMA AG   (Switzerland)

Author keywords

5 HT1A receptors; DRY motif; Fusion proteins; G proteins; Inverse agonist; Molecular models; Positive cooperativity; S 14506; Spiperone

Indexed keywords

1 [2 (4 FLUOROBENZAMIDO)ETHYL] 4 (7 METHOXY 1 NAPHTHYL)PIPERAZINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; ARGININE; BUSPIRONE; CALCIUM; G PROTEIN COUPLED RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; HYBRID PROTEIN; IPSAPIRONE; LIGAND; MAGNESIUM; MANGANESE; METITEPINE; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; N TERT BUTYL 3 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 2 PHENYLPROPIONAMIDE; SEROTONIN 1A RECEPTOR; SPIPERONE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG MECHANISM; DRUG RECEPTOR BINDING; HIPPOCAMPUS; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; RAT;

8-HYDROXY-2-(DI-N-PROPYLAMINO)TETRALIN; ANIMALS; BENZAMIDES; BINDING, COMPETITIVE; CELL MEMBRANE; CHO CELLS; CRICETINAE; DOPAMINE ANTAGONISTS; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GUANYLYL IMIDODIPHOSPHATE; HIPPOCAMPUS; HUMANS; MACROMOLECULAR SUBSTANCES; METHIOTHEPIN; MODELS, MOLECULAR; PIPERAZINES; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; RECEPTORS, SEROTONIN, 5-HT1; RECOMBINANT FUSION PROTEINS; SEROTONIN AGONISTS; SEROTONIN ANTAGONISTS; SODIUM; TRANSFECTION;

EID: 0035128982     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(00)00162-3     Document Type: Article

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