Sustained activation of a G protein-coupled receptor via 'anchored' agonist binding. Molecular localization of the salmeterol exosite within the β 2-adrenergic receptor

Journal of Biological Chemistry

Volumn 271, Issue 39, 1996, Pages 24029-24035

  Green, Stuart A ^a,c   Spasoff, Andrew P ^a   Coleman, Robert A ^b   Johnson, Malcolm ^b   Liggett, Stephen B ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADRENALIN; BETA 2 ADRENERGIC RECEPTOR; FORMOTEROL; GUANINE NUCLEOTIDE BINDING PROTEIN; ISOPRENALINE; NORADRENALIN; SALBUTAMOL; SALMETEROL;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; BINDING AFFINITY; DRUG BINDING SITE; DRUG MECHANISM; MEMBRANE BINDING; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING;

ADRENERGIC BETA-AGONISTS; ALBUTEROL; BINDING SITES; EXTRACELLULAR SPACE; GTP-BINDING PROTEINS; LIGANDS; MODELS, MOLECULAR; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, ADRENERGIC, BETA-1; RECEPTORS, ADRENERGIC, BETA-2; RECOMBINANT FUSION PROTEINS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION;

EID: 0029841642     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.271.39.24029     Document Type: Article

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