-
1
-
-
0032889037
-
Microglia express CCR5, CXCR4, and CCR3, but of these, CCR5 is the principal coreceptor for human immunodeficiency virus type 1 dementia isolates
-
(1999)
J. Virol.
, vol.73
, pp. 205-213
-
-
Albright, A.V.1
Shieh, J.T.C.2
Itoh, T.3
Lee, B.4
Pleasure, D.5
O'Connor, M.J.6
Doms, R.W.7
González-Scarano, F.8
-
4
-
-
0030018156
-
CC-CKR5: A RANTES, MIP-1α and MIP-1β receptor as a fusion cofactor for macrophage-tropic HIV-1
-
(1996)
Science
, vol.272
, pp. 1955-1958
-
-
Alkhatib, G.1
Combadiere, C.2
Broder, C.C.3
Feng, Y.4
Kennedy, P.E.5
Murphy, P.M.6
Berger, E.A.7
-
6
-
-
13044256383
-
A small-molecule, nonpeptide CCR5 antagonist with highly potent and selective anti-HIV-1 activity
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5698-5703
-
-
Baba, M.1
Nishimura, O.2
Kanzaki, N.3
Okamoto, M.4
Sawada, H.5
Iizawa, Y.6
Shiraishi, M.7
Aramaki, Y.8
Okonogi, K.9
Ogawa, Y.10
Meguro, K.11
Fujino, M.12
-
9
-
-
0041447286
-
A new classification for HIV-1
-
(1998)
Nature
, vol.391
, pp. 340
-
-
Berger, E.A.1
Doms, R.W.2
Fenyö, E.-M.3
Korber, B.T.M.4
Littman, D.R.5
Moore, J.P.6
Sattentau, Q.J.7
Schuitemaker, H.8
Sodroski, J.9
Weiss, R.A.10
-
12
-
-
1842415431
-
Coreceptor usage of primary human immunodeficiency virus type 1 isolates varies according to biological phenotype
-
(1997)
J. Virol.
, vol.71
, pp. 7478-7487
-
-
Björndal, A.1
Deng, H.2
Jansson, M.3
Fiore, J.R.4
Colognesi, C.5
Karlsson, A.6
Albert, J.7
Scarlatti, G.8
Littman, D.R.9
Fenyö, E.M.10
-
13
-
-
0033520930
-
Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 env protein
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34719-34727
-
-
Blanpain, C.1
Doranz, B.J.2
Vakili, J.3
Rucker, J.4
Govaerts, C.5
Baik, S.S.W.6
Lorthioir, O.7
Migeotte, I.8
Libert, F.9
Baleux, F.10
Vassart, G.11
Doms, R.W.12
Parmentier, M.13
-
16
-
-
0026134432
-
Neuropathology of human immunodeficiency virus infection
-
(1991)
Brain Pathol.
, vol.1
, pp. 163-175
-
-
Budka, H.1
-
18
-
-
0030025979
-
Cooperative effects of the human immunodeficiency virus type 1 envelope variable loops V1 and V3 in mediating infectivity for T cells
-
(1996)
J. Virol.
, vol.70
, pp. 1310-1316
-
-
Carillo, A.1
Ratner, L.2
-
19
-
-
0022408686
-
Acute encephalopathy coincident with seroconversion for anti-HTLV-III
-
(1985)
Lancet
, vol.2
, pp. 1206-1208
-
-
Carne, C.A.1
Tedder, R.S.2
Smith, A.3
Sutherland, S.4
Elkington, S.G.5
Daly, H.M.6
Preston, F.E.7
Craske, J.8
-
23
-
-
0005014748
-
The b-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates
-
(1996)
Cell
, vol.85
, pp. 1135-1148
-
-
Choe, H.1
Farzan, M.2
Sun, Y.3
Sullivan, N.4
Rollins, B.5
Ponath, P.D.6
Wu, J.7
Mackay, C.R.8
LaRosa, G.9
Newman, W.10
Gerard, N.11
Gerard, C.12
Sodroski, J.13
-
25
-
-
0025761245
-
High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection
-
(1991)
N. Engl. J. Med.
, vol.324
, pp. 954-960
-
-
Clark, S.J.1
Saag, M.S.2
Decker, W.D.3
Campbell-Hill, S.4
Roberson, J.L.5
Veldkamp, P.J.6
Kappes, J.C.7
Hahn, B.H.8
Shaw, G.M.9
-
27
-
-
0026661095
-
Early viral brain invasion in iatrogenic human immunodeficiency virus infection
-
(1992)
Neurology
, vol.42
, pp. 1736-1739
-
-
Davis, L.E.1
Hjelle, B.L.2
Miller, V.E.3
Palmer, D.L.4
Llewellyn, A.L.5
Merlin, T.L.6
Young, S.A.7
Mills, R.G.8
Wachsman, W.9
Wiley, C.A.10
-
28
-
-
15844419153
-
Identification of a major co-receptor for primary isolates of HIV-1
-
(1996)
Nature
, vol.381
, pp. 661-666
-
-
Deng, H.1
Liu, R.2
Ellmeier, W.3
Choe, S.4
Unutmaz, D.5
Burkhart, M.6
Di Marzio, P.7
Marmon, S.8
Sutton, R.E.9
Hill, C.M.10
Davis, C.B.11
Peiper, S.C.12
Schall, T.J.13
Littman, D.R.14
Landau, N.R.15
-
29
-
-
0030729012
-
Direct ex vivo flow cytometric analysis of human microglial cell CD4 expression: Examination of central nervous system biopsy specimens from HIV-seropositive patients and patients with other neurological disease
-
(1997)
AIDS
, vol.11
, pp. 1699-1708
-
-
Dick, A.D.1
Pell, M.2
Brew, B.J.3
Foulcher, E.4
Sedgwick, J.D.5
-
30
-
-
0030604727
-
A dual-tropic primary HIV-1 isolate that uses fusin and the β-chemokine receptors CKR-5, CKR-3 and CKR-2b as fusin cofactors
-
(1996)
Cell
, vol.85
, pp. 1149-1158
-
-
Doranz, B.1
Rucker, J.2
Yi, Y.3
Smyth, R.J.4
Samson, M.5
Peiper, S.C.6
Parmentier, M.7
Collman, R.G.8
Doms, R.W.9
-
31
-
-
0030861238
-
Two distinct CCR5 domains can mediate coreceptor usage by human immunodeficiency virus type 1
-
(1997)
J. Virol.
, vol.71
, pp. 6305-6314
-
-
Doranz, B.J.1
Lu, Z.H.2
Rucker, J.3
Zhang, T.Y.4
Sharron, M.5
Cen, Y.H.6
Wang, Z.X.7
Guo, H.H.8
Du, J.G.9
Accavitti, M.A.10
Doms, R.W.11
Peiper, S.C.12
-
32
-
-
15844389650
-
+ cells is mediated by the chemokine receptor CC-CKR-5
-
(1996)
Nature
, vol.381
, pp. 667-673
-
-
Dragic, T.1
Litwin, V.2
Allaway, G.P.3
Martin, S.R.4
Huang, Y.5
Nagashima, K.A.6
Cayanan, C.7
Maddon, P.J.8
Koup, R.A.9
Moore, J.P.10
Paxton, W.A.11
-
33
-
-
0031984539
-
Amino-terminal substitutions in the CCR5 coreceptor impair gp120 binding and human immunodeficiency virus type 1 entry
-
(1998)
J. Virol.
, vol.72
, pp. 279-285
-
-
Dragic, T.1
Trkola, A.2
Lin, S.W.3
Nagashima, K.A.4
Kajumo, F.5
Zhao, L.6
Olson, W.C.7
Wu, L.8
Mackay, C.R.9
Allaway, G.P.10
Sakmar, T.P.11
Moore, J.P.12
Maddon, P.J.13
-
34
-
-
0034625144
-
A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 5639-5644
-
-
Dragic, T.1
Trokla, A.2
Thompson, D.A.D.3
Cormier, E.G.4
Kajumo, F.A.5
Maxwell, E.6
Lin, S.W.7
Ying, W.8
Smith, S.O.9
Sakmar, T.P.10
Moore, J.P.11
-
35
-
-
0031985314
-
Spontaneous mutations in the env gene of human immunodeficiency virus type 1 NDK isolate are associated with a CD4-independent entry phenotype
-
(1998)
J. Virol.
, vol.72
, pp. 512-519
-
-
Dumonceaux, J.1
Nisole, S.2
Chanel, C.3
Quivet, L.4
Amara, A.5
Baleux, F.6
Briand, P.7
Hazan, U.8
-
38
-
-
0031883554
-
A tyrosinerich region in the N terminus of CCR5 is important for human immunodeficiency virus type 1 entry and mediates an association between gp120 and CCR5
-
(1998)
J. Virol.
, vol.72
, pp. 1160-1164
-
-
Farzan, M.1
Choe, H.2
Vaca, L.3
Martin, K.4
Sun, Y.5
Desjardins, E.6
Ruffing, N.7
Wu, L.8
Wyatt, R.9
Gerard, N.10
Gerard, C.11
Sodroski, J.12
-
39
-
-
0032953920
-
+ T cells provides a mechanism for livelong persistence of HIV-1, even in patients on effective combination therapy
-
(1999)
Nat. Med.
, vol.5
, pp. 512-517
-
-
Finzi, D.1
Blankson, J.2
Siliciano, J.D.3
Margolick, J.B.4
Chadwick, K.5
Pierson, T.6
Smith, K.7
Lisziewicz, J.8
Lori, F.9
Flexner, C.10
Quinn, T.C.11
Chaisson, R.E.12
Rosenberg, E.13
Walker, B.14
Gange, S.15
Gallant, J.16
Siliciano, R.F.17
-
41
-
-
2642676073
-
Role of the beta-chemokine receptors CCR3 and CCR5 in human immunodeficiency virus type 1 infection of monocytes and microglia
-
(1998)
J. Virol.
, vol.72
, pp. 3351-3361
-
-
Ghorpade, A.1
Xia, M.Q.2
Hyman, B.T.3
Persidsky, Y.4
Nukuna, A.5
Bock, P.6
Che, M.7
Limoges, J.8
Gendelman, H.E.9
Mackay, C.R.10
-
43
-
-
19244380883
-
CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia
-
(1997)
Nature
, vol.385
, pp. 645-649
-
-
He, J.1
Chen, Y.2
Farzan, M.3
Choe, H.4
Ohagen, A.5
Gartner, S.6
Busciglio, J.7
Yang, X.8
Hofmann, W.9
Newman, W.10
Mackay, C.R.11
Sodroski, J.12
Gabuzda, D.13
-
44
-
-
0032990223
-
Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 6359-6364
-
-
Hoffman, T.L.1
LaBranche, C.C.2
Zhang, W.3
Canziani, G.4
Robinson, J.5
Chaiken, I.6
Hoxie, J.A.7
Doms, R.W.8
-
47
-
-
0021720872
-
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV
-
(1984)
Nature
, vol.312
, pp. 767-768
-
-
Klatzmann, D.1
Champagne, E.2
Chamaret, S.3
Gruest, J.4
Guetard, D.5
Hercend, T.6
Gluckman, J.C.7
Montagnier, L.8
-
48
-
-
0022522203
-
Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy
-
(1986)
Science
, vol.233
, pp. 1089-1093
-
-
Koenig, S.1
Gendelman, H.E.2
Orenstein, J.M.3
Dal Canto, M.C.4
Pezeshkpour, G.H.5
Yungbluth, M.6
Janotta, F.7
Aksamit, A.8
Martin, M.A.9
Fauci, A.S.10
-
50
-
-
0032880105
-
Adaptation of a CCR5-using, primary human immunodeficiency virus type 1 isolate for CD4-independent replication
-
(1999)
J. Virol.
, vol.73
, pp. 8120-8126
-
-
Kolchinsky, P.1
Mirzabekov, T.2
Farzan, M.3
Kiprilov, E.4
Cayabyab, M.5
Mooney, L.J.6
Choe, H.7
Sodroski, J.8
-
53
-
-
0032712246
-
Determinants of CD4 independence for a human immunodeficiency virus type 1 variant map outside regions required for coreceptor specificity
-
(1999)
J. Virol.
, vol.73
, pp. 10310-10319
-
-
LaBranche, C.C.1
Hoffman, T.L.2
Romano, J.3
Haggarty, B.S.4
Edwards, T.G.5
Matthews, T.J.6
Doms, R.W.7
Hoxie, J.A.8
-
56
-
-
0033515588
-
Epitope mapping of CCR5 reveals multiple conformational states and distinct overlapping structures involved in chemokine and coreceptor function
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9617-9626
-
-
Lee, B.1
Sharron, M.2
Blanpain, C.3
Doranz, B.J.4
Vakili, J.5
Setoh, P.6
Berg, E.7
Liu, G.8
Guy, H.R.9
Drell, S.R.10
Parmentier, M.11
Chang, C.N.12
Price, K.13
Tsang, M.14
Doms, R.W.15
-
58
-
-
0026582808
-
Nonrandom distribution of gp120 N-linked glycosylation sites important for infectivity of human immunodeficiency virus type 1
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 2213-2217
-
-
Lee, W.R.1
Syu, W.J.2
Du, B.3
Matsuda, M.4
Tan, S.5
Wolf, A.6
Essex, M.7
Lee, T.H.8
-
63
-
-
0033942750
-
V2 loop glycosylation of the human immunodeficiency virus type 1 SF162 envelope facilitates interaction of this protein with CD4 and CCR5 receptors and protects the virus from neutralization by anti-V3 loop and anti-CD4 binding site antibodies
-
(2000)
J. Virol.
, vol.74
, pp. 6769-6776
-
-
Ly, A.1
Stamatatos, L.2
-
65
-
-
0024762317
-
Neuropathological changes in early HIV-1 dementia
-
(1989)
Ann. Neurol.
, vol.26
, pp. 681-684
-
-
McArthur, J.C.1
Becker, P.S.2
Parisi, J.E.3
Trapp, B.4
Selnes, O.A.5
Cornblath, D.R.6
Balakrishnan, J.7
Griffin, J.W.8
Price, D.9
-
66
-
-
0032169831
-
Interactions among HIV gp120, CD4, and CXCR4: Dependence on CD4 expression levels, gp120 viral origin, conservation of the gp120 COOH- and NH2-termini and V1/V2 and V3 loops, and sensitivity to neutralizing antibodies
-
(1998)
Virology
, vol.248
, pp. 394-405
-
-
Mondor, I.1
Moulard, M.2
Ugolini, S.3
Klasse, P.J.4
Hoxie, J.5
Amara, A.6
Delaunay, T.7
Wyatt, R.8
Sodroski, J.9
Sattentau, Q.J.10
-
67
-
-
0031951649
-
Evidence that antibody-mediated neutralization of human immunodeficiency virus type 1 by sera from infected individuals is independent of coreceptor usage
-
(1998)
J. Virol.
, vol.72
, pp. 1886-1893
-
-
Montefiori, D.C.1
Collman, R.G.2
Fouts, T.R.3
Zhou, J.Y.4
Bilska, M.5
Hoxie, J.A.6
Moore, J.P.7
Bolognesi, D.P.8
-
68
-
-
0028917784
-
Primary isolates of human immunodeficiency virus type 1 are relatively resistant to neutralization by monoclonal antibodies to gp120, and their neutralization is not predicted by studies with monomeric gp120
-
(1995)
J. Virol.
, vol.69
, pp. 101-109
-
-
Moore, J.P.1
Cao, Y.2
Qing, L.3
Sattentau, Q.J.4
Pyati, J.5
Koduri, R.6
Robinson, J.7
Barbas, C.F.8
Burton III, D.R.9
Ho, D.D.10
-
76
-
-
0033871164
-
Characterization of chemokine receptor utilization of viruses in the latent reservoir for human immunodeficiency virus type 1
-
(2000)
J. Virol.
, vol.74
, pp. 7824-7833
-
-
Pierson, T.1
Hoffman, T.L.2
Blankson, J.3
Finzi, D.4
Chadwick, K.5
Margolick, J.B.6
Buck, C.7
Siliciano, J.D.8
Doms, R.W.9
Siliciano, R.F.10
-
81
-
-
0031690759
-
Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differ between demented and nondemented AIDS patients
-
(1998)
J. Virol.
, vol.72
, pp. 9045-9053
-
-
Power, C.1
McArthur, J.C.2
Nath, A.3
Wehrly, K.4
Mayne, M.5
Nishio, J.6
Langelier, T.7
Johnson, R.T.8
Chesebro, B.9
-
86
-
-
0031937625
-
Multiple residues contribute to the inability of murine CCR-5 to function as a coreceptor for macrophage-tropic human immunodeficiency virus type 1 isolates
-
(1998)
J. Virol.
, vol.72
, pp. 1918-1924
-
-
Ross, T.M.1
Bieniasz, P.D.2
Cullen, B.R.3
-
87
-
-
16044365432
-
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity
-
(1996)
Cell
, vol.87
, pp. 437-446
-
-
Rucker, J.1
Samson, M.2
Doranz, B.J.3
Libert, F.4
Berson, J.F.5
Yi, Y.6
Smyth, R.J.7
Collman, R.G.8
Broder, C.C.9
Vassart, G.10
Doms, R.W.11
Parmentier, M.12
-
88
-
-
0033988632
-
Sequential CD4-coreceptor interactions in human immunodeficiency virus type 1 Env function: Soluble CD4 activates Env for coreceptor-dependent fusion and reveals blocking activities of antibodies against cryptic conserved epitopes on gp120
-
(2000)
J. Virol.
, vol.74
, pp. 326-333
-
-
Salzwedel, K.1
Smith, E.D.2
Dey, B.3
Berger, E.A.4
-
94
-
-
0033593324
-
A critical site in the core of the CCR5 chemokine receptor required for binding and infectivity of human immunodeficiency virus type 1
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 1905-1913
-
-
Siciliano, S.J.1
Kuhmann, S.E.2
Weng, Y.3
Madani, N.4
Springer, M.S.5
Lineberger, J.E.6
Danzeisen, R.7
Miller, M.D.8
Kavanaugh, M.P.9
DeMartino, J.A.10
Kabat, D.11
-
96
-
-
0031878761
-
Determinants of human immunodeficiency virus type 1 envelope glycoprotein activation by soluble CD4 and monoclonal antibodies
-
(1998)
J. Virol.
, vol.72
, pp. 6332-6338
-
-
Sullivan, N.1
Sun, Y.2
Binley, J.3
Lee, J.4
Barbas III, C.F.5
Parren, P.W.H.I.6
Burton, D.R.7
Sodroski, J.8
-
97
-
-
0031902829
-
CD4-induced conformational changes in the human immunodeficiency virus type 1 gp120 glycoprotein: Consequences for virus entry and neutralization
-
(1998)
J. Virol.
, vol.72
, pp. 4694-4703
-
-
Sullivan, N.1
Sun, Y.2
Sattentau, Q.3
Thali, M.4
Wu, D.5
Denisova, G.6
Gershoni, J.7
Robinson, J.8
Moore, J.9
Sodroski, J.10
-
101
-
-
16144365317
-
CD4-dependent, antibody-sensitive interactions between HIV-1 and its coreceptor CCR5
-
(1996)
Nature
, vol.384
, pp. 184-187
-
-
Trkola, A.1
Dragic, T.2
Arthos, J.3
Binley, J.M.4
Olson, W.C.5
Allaway, G.P.6
Cheng-Mayer, C.7
Robinson, J.8
Maddon, P.J.9
Moore, J.P.10
-
103
-
-
0025062717
-
Specific tropism of HIV-1 for microglial cells in primary human brain cultures
-
(1990)
Science
, vol.249
, pp. 549-552
-
-
Watkins, B.A.1
Dorn, H.H.2
Kelly, W.B.3
Armstrong, R.C.4
Potts, B.J.5
Michaels, F.6
Kufta, C.V.7
Dubois-Dalcq, M.8
-
105
-
-
0028024080
-
Human immunodeficiency virus encephalitis is the pathological correlate of dementia in acquired immunodeficiency syndrome
-
(1994)
Ann. Neurol.
, vol.36
, pp. 673-676
-
-
Wiley, C.A.1
Achim, C.L.2
-
109
-
-
16144365650
-
CD4-induced interaction of primary HIV-1 glycoproteins with the chemokine receptor CCR-5
-
(1996)
Nature
, vol.384
, pp. 179-183
-
-
Wu, L.1
Gerard, N.P.2
Wyatt, R.3
Choe, H.4
Parolin, C.5
Ruffing, N.6
Borsetti, A.7
Cardoso, A.A.8
Desjardin, E.9
Newman, W.10
Gerard, C.11
Sodroski, J.12
-
110
-
-
0030779808
-
Interaction of chemokine receptor CCR5 with its ligands: Multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1373-1381
-
-
Wu, L.1
LaRosa, G.2
Kassam, N.3
Gordon, C.J.4
Heath, H.5
Ruffing, N.6
Chen, H.7
Humblias, J.8
Samson, M.9
Parmentier, M.10
Moore, J.P.11
Mackay, C.R.12
-
111
-
-
0030987288
-
CCR5 levels and expression pattern correlate with infectability by macrophage-tropic HIV-1, in vitro
-
(1997)
J. Exp. Med.
, vol.185
, pp. 1681-1691
-
-
Wu, L.1
Paxton, W.A.2
Kassam, N.3
Ruffing, N.4
Rottman, J.B.5
Sullivan, N.6
Choe, H.7
Sodroski, J.8
Newman, W.9
Koup, R.A.10
Mackay, C.R.11
-
112
-
-
0028965263
-
Characterization of neutralization epitopes in the V2 region of human immunodeficiency virus type 1 gp120: Role of glycosylation in the correct folding of the V1/V2 domain
-
(1995)
J. Virol.
, vol.69
, pp. 2271-2278
-
-
Wu, Z.1
Kayman, S.C.2
Honnen, W.3
Revesz, K.4
Chen, H.5
Vijh-Warrier, S.6
Tilley, S.A.7
McKeating, J.8
Shotton, C.9
Pinter, A.10
-
116
-
-
0002370344
-
Culture of glial cells from human brain biopsies
-
S. Fedoroff and A. Richardson (ed.), Protocols for neural cell culture. Humana Press, Totowa, N.J.
-
(1992)
, pp. 81-96
-
-
Yong, V.W.1
Antel, J.P.2
-
117
-
-
0033609373
-
Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1605-1613
-
-
Zhang, L.1
Ramratnam, B.2
Tenner, R.K.3
He, Y.4
Vesanen, M.5
Lewin, S.6
Talal, A.7
Racz, P.8
Perelson, A.S.9
Korber, B.T.10
Markowitz, M.11
Ho, D.D.12
-
118
-
-
0033587488
-
Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic
-
(1999)
Biochemistry
, vol.38
, pp. 9405-9416
-
-
Zhang, W.1
Canziani, G.2
Plugariu, C.3
Wyatt, R.4
Sodroski, J.5
Sweet, R.6
Kwong, P.7
Hendrickson, W.8
Chaiken, I.9
|