Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2

Journal of Neuropathology and Experimental Neurology

Volumn 57, Issue 12, 1998, Pages 1164-1167

  Stemmer Rachamimov, Anat O ^a   Ino, Yasushi ^a   Lim, Zi Yi ^a   Jacoby, Lee B ^a   MacCollin, Mia ^a   Gusella, James F ^a   Ramesh, Vijaya ^a   Louis, David N ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Merlin; Neurofibromatosis 2; NF2; Schwann cell; Schwannoma

Indexed keywords

MERLIN;

ADULT; ARTICLE; CASE REPORT; FRAMESHIFT MUTATION; GENE EXPRESSION; GENE LOSS; HETEROZYGOSITY LOSS; HUMAN; MALE; NEURILEMOMA; NEUROFIBROMATOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0031745533     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005072-199812000-00008     Document Type: Article

References (9)

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8. Stemmer-Rachamimov AO, Xu L, Gonzalez-Agosti C, et al. Universal absence of merlin, but not other ERM family members, in schwannomas. Am J Pathol 1997;152:1649-54
9. Carroll SL, Frohnert PW. Analysis of a potential neuregulin/erbB receptor autocrine loop in Schwann cell neoplasia. J Neuropathol Exp Neurol 1997;56:583