Purine analogs as CDK enzyme inhibitory agents: A survey and QSAR analysis

Progress in Drug Research

Volumn 56, Issue , 2001, Pages 155-193

  Lee, Allen D ^a   Ren, Shijun ^a   Lien, Eric J ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Cancer; CDK inhibitors; CDK1; CDK2; Cell cycle; Clinical trials; Molecular modeling; Physicochemical properties; Proliferative disorders; Purine analogs; QSAR; SAR

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR; FLAVOPIRIDOL; OLOMOUCINE; PURINE DERIVATIVE; PURVALANOL A; PURVALANOL B; ROSCOVITINE; STAUROSPORINE;

CELL CYCLE; CELL PROLIFERATION; CLINICAL TRIAL; DRUG TARGETING; ENZYME INHIBITION; HUMAN; MOLECULAR MODEL; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; REVIEW; X RAY CRYSTALLOGRAPHY;

EID: 0035036460     PISSN: 0071786X     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-3-0348-8319-1_4     Document Type: Review

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