메뉴 건너뛰기




Volumn 18, Issue 2 A, 1998, Pages 751-755

Roscovitine inhibits the proliferative activity of immortal and neoplastic human breast epithelial cells

Author keywords

Cell proliferation; Cyclin dependent kinase inhibitors; Roscovitine

Indexed keywords

ANTIMITOTIC AGENT; CYCLIN DEPENDENT KINASE; ENZYME INHIBITOR; ESTROGEN RECEPTOR; PROTEIN KINASE; ROSCOVITINE; UNCLASSIFIED DRUG;

EID: 0031813095     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (25)

References (24)
  • 1
    • 0028171292 scopus 로고
    • G1 phase progression: Cycling on cue
    • Sherr CJ: G1 phase progression: Cycling on cue. Cell 79: 551-555, 1994.
    • (1994) Cell , vol.79 , pp. 551-555
    • Sherr, C.J.1
  • 2
    • 0027938207 scopus 로고
    • Ordering S phase and M phase in the cell cycle
    • Nurse P: Ordering S phase and M phase in the cell cycle. Cell 79: 547-550, 1994.
    • (1994) Cell , vol.79 , pp. 547-550
    • Nurse, P.1
  • 3
    • 0028568315 scopus 로고
    • Cell cycle and cancer
    • Hartwell LH, Kastan MB: Cell cycle and cancer. Science 266: 1821-1828, 1994.
    • (1994) Science , vol.266 , pp. 1821-1828
    • Hartwell, L.H.1    Kastan, M.B.2
  • 4
    • 0028820762 scopus 로고
    • The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo
    • Yang Z-H, Perkins ND, Ohno, T, Nabel EG, Nabel GJ: The p21 cyclin-dependent kinase inhibitor suppresses tumorigenicity in vivo. Nature Med 1: 1052-1056, 1995.
    • (1995) Nature Med , vol.1 , pp. 1052-1056
    • Yang, Z.-H.1    Perkins, N.D.2    Ohno, T.3    Nabel, E.G.4    Nabel, G.J.5
  • 6
    • 0027742184 scopus 로고
    • Distinct roles for cyclin-dependent kinases in cell cycle control
    • Van den Heuvel S, Harlow E: Distinct roles for cyclin-dependent kinases in cell cycle control. Science 262: 2050-2054, 1993.
    • (1993) Science , vol.262 , pp. 2050-2054
    • Van Den Heuvel, S.1    Harlow, E.2
  • 7
    • 0028931265 scopus 로고
    • Principles of CDK regulation
    • Morgan DO: Principles of CDK regulation. Nature 374: 1311-1314, 1995.
    • (1995) Nature , vol.374 , pp. 1311-1314
    • Morgan, D.O.1
  • 8
    • 0028915222 scopus 로고
    • Molecular foundations of cancer: New targets for intervention
    • Karp JE and Broder S: Molecular foundations of cancer: New targets for intervention. Nature Med 1: 309-320, 1995.
    • (1995) Nature Med , vol.1 , pp. 309-320
    • Karp, J.E.1    Broder, S.2
  • 9
    • 0029670838 scopus 로고    scopus 로고
    • Inhibition of G1 cyclin- dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2
    • Gorospe M, Liu Y, Xu Q, Chrest FJ and Holbrook NJ: Inhibition of G1 cyclin- dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2. Mol Cell Biol 16: 762-770, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 762-770
    • Gorospe, M.1    Liu, Y.2    Xu, Q.3    Chrest, F.J.4    Holbrook, N.J.5
  • 10
    • 0028988585 scopus 로고
    • Inhibitors of mammalian G1 cyclindependent kinases
    • Sherr CJ and Roberts J: Inhibitors of mammalian G1 cyclindependent kinases. Genes and Dev 9: 1149-1163, 1995.
    • (1995) Genes and Dev , vol.9 , pp. 1149-1163
    • Sherr, C.J.1    Roberts, J.2
  • 11
    • 0028991396 scopus 로고
    • Mutation of cell cycle regulators. Biological and clinical implications in human neoplasia
    • Cordon-Cardo C: Mutation of cell cycle regulators. Biological and clinical implications in human neoplasia. Am J Pathol 147: 545-560, 1995.
    • (1995) Am J Pathol , vol.147 , pp. 545-560
    • Cordon-Cardo, C.1
  • 12
    • 0030271304 scopus 로고    scopus 로고
    • Chemical inhibitors of cyclin-dependent kinases
    • Meijer L: Chemical inhibitors of cyclin-dependent kinases. Trends Cell Biol 6: 393-397, 1996.
    • (1996) Trends Cell Biol , vol.6 , pp. 393-397
    • Meijer, L.1
  • 13
    • 0031055563 scopus 로고    scopus 로고
    • Cytokin- derived cyclin-dependent kinase inhibitors: Synthesis and cdc2 inhibitory activity of olomoucine and related compounds
    • Havlicek L, Hanus J, Vesely J, Leclerc S, Meijer L. Shaw G and Strnad M: Cytokin- derived cyclin-dependent kinase inhibitors: Synthesis and cdc2 inhibitory activity of olomoucine and related compounds. J Med Chem 40: 408-412, 1997.
    • (1997) J Med Chem , vol.40 , pp. 408-412
    • Havlicek, L.1    Hanus, J.2    Vesely, J.3    Leclerc, S.4    Meijer, L.5    Shaw, G.6    Strnad, M.7
  • 14
    • 0031028163 scopus 로고    scopus 로고
    • Inhibition of cyclin-dependent kinases by purine analogues. Crystal structure of human cdk2 complexed with roscovitine
    • Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad, M and Kim S-H: Inhibition of cyclin-dependent kinases by purine analogues. Crystal structure of human cdk2 complexed with roscovitine. Eur J Biochem 243: 518-526, 1997.
    • (1997) Eur J Biochem , vol.243 , pp. 518-526
    • Azevedo, W.F.1    Leclerc, S.2    Meijer, L.3    Havlicek, L.4    Strnad, M.5    Kim, S.-H.6
  • 15
    • 0031037714 scopus 로고    scopus 로고
    • Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5
    • Meijer L, Bordne A, Mulner O, Chong JPJ, Blow JJ, Inagaki M, Delcros J-G, and Moulinoux J-P: Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5. Eur J Biochem 243: 527-536, 1997.
    • (1997) Eur J Biochem , vol.243 , pp. 527-536
    • Meijer, L.1    Bordne, A.2    Mulner, O.3    Chong, J.P.J.4    Blow, J.J.5    Inagaki, M.6    Delcros, J.-G.7    Moulinoux, J.-P.8
  • 16
    • 0029888119 scopus 로고    scopus 로고
    • Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A but not apoptosis
    • Rudolph B, Saffric JZ, Henglein B, Muller R, Ansorge W and Eilers M: Activation of cyclin-dependent kinases by Myc mediates induction of cyclin A but not apoptosis. EMBO J 15: 3065-3076, 1996.
    • (1996) EMBO J , vol.15 , pp. 3065-3076
    • Rudolph, B.1    Saffric, J.Z.2    Henglein, B.3    Muller, R.4    Ansorge, W.5    Eilers, M.6
  • 17
    • 0015762456 scopus 로고
    • A human cell line from a pleural effusion derived from a breast carcinoma
    • Soule HD, Vazquez J, Long A, Albert S and Brennan MJ: A human cell line from a pleural effusion derived from a breast carcinoma. J Natl Cancer Inst 51: 1409-1412, 1973.
    • (1973) J Natl Cancer Inst , vol.51 , pp. 1409-1412
    • Soule, H.D.1    Vazquez, J.2    Long, A.3    Albert, S.4    Brennan, M.J.5
  • 18
    • 0015898197 scopus 로고
    • Estrogen receptor in a human cell line (MCF-7) from breast carcinoma
    • Brooks SC, Locke ER and Soule HD: Estrogen receptor in a human cell line (MCF-7) from breast carcinoma. J Biol Chem 248: 6251-6253, 1973.
    • (1973) J Biol Chem , vol.248 , pp. 6251-6253
    • Brooks, S.C.1    Locke, E.R.2    Soule, H.D.3
  • 20
    • 0029745065 scopus 로고    scopus 로고
    • Expression of CDK inhibitor genes in immortalized and carcinoma derived breast cell lines
    • Zhou J-N and Linder S: Expression of CDK inhibitor genes in immortalized and carcinoma derived breast cell lines. Anticancer Res 16: 1931-1936, 1996.
    • (1996) Anticancer Res 1 , vol.6 , pp. 1931-1936
    • Zhou, J.-N.1    Linder, S.2
  • 23
    • 0029116545 scopus 로고
    • Inactivation of Cdc2 increases the level of apoptosis induced by DNA damage
    • Ongkeko W, Ferguson DJP, Harris AL and Norbury C: Inactivation of Cdc2 increases the level of apoptosis induced by DNA damage. Cell Science 108: 2897-2904, 1995.
    • (1995) Cell Science , vol.108 , pp. 2897-2904
    • Ongkeko, W.1    Djp, F.2    Harris, A.L.3    Norbury, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.