Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with Roscovitine, a novel cyclin-dependent kinase antagonist

Journal of Clinical Investigation

Volumn 100, Issue 10, 1997, Pages 2512-2520

  Pippin, Jeffrey W ^a   Qu, Qingyun ^a   Meijer, Laurent ^b   Shankland, Stuart J ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b STATION BIOLOGIQUE   (France)

Author keywords

Cell cycle; Cyclins; Kidney; Proliferation; Roscovitine

Indexed keywords

COLLAGEN TYPE 4; CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR; FIBRONECTIN; LAMININ; ROSCOVITINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL CYCLE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG MECHANISM; INFLAMMATION; INTRAPERITONEAL DRUG ADMINISTRATION; MESANGIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROLIFERATIVE GLOMERULONEPHRITIS; RAT;

EID: 0030781307     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119793     Document Type: Article

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