Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signalling sensitizes endothelial cells to TNF-α cytotoxicity

Cell Death and Differentiation

Volumn 8, Issue 5, 2001, Pages 528-536

  Zhang, L ^a   Himi, T ^a   Morita, I ^a   Murota, S ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Akt; Apoptosis; MAP kinase; P13 kinase; Tumor necrosis factor

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 8; CASPASE 9; CYTOCHROME C; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CAROTID ARTERY; CELL PROTECTION; CONTROLLED STUDY; CYTOTOXICITY; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; GENE ACTIVATION; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; SENSITIZATION; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; BLOTTING, WESTERN; BUTADIENES; CASPASE 8; CASPASE 9; CASPASES; CATTLE; CELLS, CULTURED; CHROMONES; CYTOCHROME C GROUP; ENDOTHELIUM, VASCULAR; ENZYME ACTIVATION; ENZYME INHIBITORS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; MAP KINASE SIGNALING SYSTEM; MEMBRANE POTENTIALS; MITOCHONDRIA; MITOGEN-ACTIVATED PROTEIN KINASES; MORPHOLINES; NF-KAPPA B; NITRILES; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035009799     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400838     Document Type: Article

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