Selective up-regulation of phosphatidylinositol 3'-kinase activity in Th2 cells inhibits caspase-8 cleavage at the death-inducing complex: A mechanism for Th2 resistance from Fas-mediated apoptosis

Journal of Immunology

Volumn 163, Issue 9, 1999, Pages 4772-4779

  Varadhachary, Arun S ^a   Peter, Marcus E ^b,c   Perdow, Somia N ^a   Krammer, Peter H ^b   Salgame, Padmini ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CD3 ANTIGEN; FAS ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE;

APOPTOSIS; ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; T LYMPHOCYTE ACTIVATION; T LYMPHOCYTE SUBPOPULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANDROSTADIENES; ANTIGENS, CD3; ANTIGENS, CD95; APOPTOSIS; CARRIER PROTEINS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CASPASE 8; CASPASE 9; CASPASES; CATALYSIS; CLONE CELLS; ENZYME ACTIVATION; ENZYME INHIBITORS; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; HYDROLYSIS; IMMUNITY, NATURAL; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LYMPHOCYTE ACTIVATION; PEPTIDE FRAGMENTS; SIGNAL TRANSDUCTION; TH1 CELLS; TH2 CELLS; UP-REGULATION;

EID: 0032711440     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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