Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade

Neuroscience

Volumn 94, Issue 4, 1999, Pages 1213-1218

  Fink, K B ^a,b   Andrews, L J ^a   Butler, W E ^a   Ona, V O ^c   Li, M ^c   Bogdanov, M ^a   Endres, M ^a   Khan, S Q ^c   Namura, S ^a   Stieg, P E ^c   Beal, M F ^a   Moskowitz, M A ^a   Yuan, J ^d   Friedlander, R M ^a,c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b UNIVERSITY OF BONN   (Germany)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Apoptosis; Caspase inhibition; Caspase 1; DNA fragmentation; Interleukin 1 converting enzyme; TUNEL

Indexed keywords

CASPASE; CASPASE INHIBITOR; DNA FRAGMENT; FREE RADICAL; INTERLEUKIN 1BETA CONVERTING ENZYME;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN INJURY; BRAIN PROTECTION; BRAIN TISSUE; CELL DEATH; CONTROLLED STUDY; ENZYME INHIBITION; HEMISPHERE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

AMINO ACID CHLOROMETHYL KETONES; ANIMALS; BRAIN; BRAIN INJURIES; CASPASE 1; CYSTEINE PROTEINASE INHIBITORS; DNA FRAGMENTATION; HYDROXYL RADICAL; INTERLEUKIN-1; MICE; MICE, TRANSGENIC; NEUROPROTECTIVE AGENTS;

EID: 0032708427     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(99)00345-0     Document Type: Article

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