메뉴 건너뛰기




Volumn 282, Issue 3, 1997, Pages 1389-1395

Human liver CYP2B6-catalyzed hydroxylation of RP 73401

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; ORPHENADRINE; PICLAMILAST;

EID: 0030988863     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (53)

References (20)
  • 1
    • 0002769936 scopus 로고    scopus 로고
    • Pharmacokinetics: The dynamics of drug absorption, distribution, and elimination
    • ed. by L. Goodman, A. Gilman, J. Hardman, A. Gilman and L. Limbird, McGraw-Hill Companies, New York, NY
    • BENET, L., KROETZ, D. AND SHEINER, L.: Pharmacokinetics: The dynamics of drug absorption, distribution, and elimination. In Goodman and Gilman's The Pharmacological Basis of Therapeutics, ed. by L. Goodman, A. Gilman, J. Hardman, A. Gilman and L. Limbird, pp. 3-28, McGraw-Hill Companies, New York, NY, 1996.
    • (1996) Goodman and Gilman's the Pharmacological Basis of Therapeutics , pp. 3-28
    • Benet, L.1    Kroetz, D.2    Sheiner, L.3
  • 2
    • 0027154768 scopus 로고
    • Stereo- and regioselective N-and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes
    • CASHMAN, J., YANG, Z., YANG, L. AND WRIGHTON, S.: Stereo- and regioselective N-and S-oxidation of tertiary amines and sulfides in the presence of adult human liver microsomes. Drug Metab. Dispos. 21: 492-501, 1993.
    • (1993) Drug Metab. Dispos. , vol.21 , pp. 492-501
    • Cashman, J.1    Yang, Z.2    Yang, L.3    Wrighton, S.4
  • 3
    • 0027369366 scopus 로고
    • Differential activation of cyclophosphamide and ifosphamide by cytochromes P-4502B 3A in human liver microsomes
    • CHANG, T., WEBER, G., CRESPI, C. AND WAXMAN, D.: Differential activation of cyclophosphamide and ifosphamide by cytochromes P-4502B 3A in human liver microsomes. Cancer Res. 53: 5629-5637, 1993.
    • (1993) Cancer Res. , vol.53 , pp. 5629-5637
    • Chang, T.1    Weber, G.2    Crespi, C.3    Waxman, D.4
  • 6
    • 0030891968 scopus 로고    scopus 로고
    • Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes
    • GUO, Z., RAEISSI, S., WHITE, R. AND STEVENS, J.: Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes. Drug Metab. Dispos. 28: 390-393, 1997.
    • (1997) Drug Metab. Dispos. , vol.28 , pp. 390-393
    • Guo, Z.1    Raeissi, S.2    White, R.3    Stevens, J.4
  • 7
    • 0029833258 scopus 로고    scopus 로고
    • Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin
    • HEYN, H., WHITE, R. AND STEVENS, J.: Catalytic role of cytochrome P4502B6 in the N-demethylation of S-mephenytoin. Drug Metab. Dispos. 24: 948-954, 1996.
    • (1996) Drug Metab. Dispos. , vol.24 , pp. 948-954
    • Heyn, H.1    White, R.2    Stevens, J.3
  • 8
    • 0023258883 scopus 로고
    • High performance liquid chromatographic analysis for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase and dextromethorphan O-demethylase in microsomes and purified cytoehrome P450 isozymes of human liver
    • KRONBACH, T., MATHYS, D., GUT, J., CATIN, T. AND MEYER, U.: High performance liquid chromatographic analysis for bufuralol 1′-hydroxylase, debrisoquine 4-hydroxylase and dextromethorphan O-demethylase in microsomes and purified cytoehrome P450 isozymes of human liver. Anal. Biochem. 162: 24-32, 1987.
    • (1987) Anal. Biochem. , vol.162 , pp. 24-32
    • Kronbach, T.1    Mathys, D.2    Gut, J.3    Catin, T.4    Meyer, U.5
  • 11
    • 0027164208 scopus 로고
    • Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae
    • MICHAELI, T., BLOOM, T., MARTINS, T., LOUGHNEY, K., FERGUSON, K., RIGGES, M., RODGERS, L., BEAVO, J. AND WIGLER, M.: Isolation and characterization of a previously undetected human cAMP phosphodiesterase by complementation of cAMP phosphodiesterase-deficient Saccharomyces cerevisiae. J. Biol. Chem. 268: 12925-12932, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12925-12932
    • Michaeli, T.1    Bloom, T.2    Martins, T.3    Loughney, K.4    Ferguson, K.5    Rigges, M.6    Rodgers, L.7    Beavo, J.8    Wigler, M.9
  • 13
    • 0028858960 scopus 로고
    • Cytochrome P450 inhibitors: Evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes
    • NEWTON, D., WANG, R. AND LU, A.: Cytochrome P450 inhibitors: evaluation of specificities in the in vitro metabolism of therapeutic agents by human liver microsomes. Drug Metab. Dispos. 23: 154-158, 1995.
    • (1995) Drug Metab. Dispos. , vol.23 , pp. 154-158
    • Newton, D.1    Wang, R.2    Lu, A.3
  • 14
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature
    • OMURA, T. AND SATO, R.: The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein nature. J. Biol. Chem. 239: 2370-2378, 1964.
    • (1964) J. Biol. Chem. , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 15
    • 0027462638 scopus 로고
    • Understanding consequences of concurrent therapies
    • PECK, C., TEMPLE, R. AND COLLINS, J.: Understanding consequences of concurrent therapies. J. Am. Med. Assoc. 269: 1550-1552, 1993.
    • (1993) J. Am. Med. Assoc. , vol.269 , pp. 1550-1552
    • Peck, C.1    Temple, R.2    Collins, J.3
  • 16
    • 0025029675 scopus 로고
    • Rapid, high-yield oxidation of Hantzch-type 1,4-dihydropyridines with ceric ammonium nitrate
    • PFISTER, J.: Rapid, high-yield oxidation of Hantzch-type 1,4-dihydropyridines with ceric ammonium nitrate. Synthesis 8: 689-690, 1990.
    • (1990) Synthesis , vol.8 , pp. 689-690
    • Pfister, J.1
  • 18
    • 0030077735 scopus 로고    scopus 로고
    • Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine
    • RING, B., CATLOW, J., LINDSAY, T., GILLESPIE, T., ROSKOS, L., CERIMELE, B., SWANSON, S., HAMMAN, M. AND WRIGHTON, S.: Identification of the human cytochromes P450 responsible for the in vitro formation of the major oxidative metabolites of the antipsychotic agent olanzapine, J. Pharmacol. Exp. Ther. 276: 658-666, 1996.
    • (1996) J. Pharmacol. Exp. Ther. , vol.276 , pp. 658-666
    • Ring, B.1    Catlow, J.2    Lindsay, T.3    Gillespie, T.4    Roskos, L.5    Cerimele, B.6    Swanson, S.7    Hamman, M.8    Wrighton, S.9
  • 19
    • 0021098075 scopus 로고
    • Purification and characterization of six cytochrome P-450 isozymes from human liver microsomes
    • WANG, P., BEAUNE, P., KAMINSKY, L., DANNAN, G., KAHZUBARI, F., LARREY, D. AND GUENGERICH, F.: Purification and characterization of six cytochrome P-450 isozymes from human liver microsomes. Biochemistry 22: 5375-5383, 1983.
    • (1983) Biochemistry , vol.22 , pp. 5375-5383
    • Wang, P.1    Beaune, P.2    Kaminsky, L.3    Dannan, G.4    Kahzubari, F.5    Larrey, D.6    Guengerich, F.7
  • 20
    • 0026750647 scopus 로고
    • The human hepatic cytochromes P450 involved in drug metabolism
    • WRIGHTON, S. AND STEVENS, J.: The human hepatic cytochromes P450 involved in drug metabolism. Crit. Rev. Toxicol. 22: 1-21, 1993.
    • (1993) Crit. Rev. Toxicol. , vol.22 , pp. 1-21
    • Wrighton, S.1    Stevens, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.