Roles of CYP2A6 and CYP2B6 in nicotine C-oxidation by human liver microsomes

Archives of Toxicology

Volumn 73, Issue 2, 1999, Pages 65-70

  Yamazaki, Hiroshi ^a,b   Inoue, Kiyoshi ^a   Hashimoto, Masafumi ^a   Shimada, Tsutomu ^a  

^a OSAKA PREFECTURAL INSTITUTE OF PUBLIC HEALTH   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

CYP2A6; CYP2B6; Human P450; Liver microsomes; Nicotine

Indexed keywords

CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; CYTOCHROME P450 ISOENZYME; CYTOCHROME P450 REDUCTASE; NICOTINE; UNCLASSIFIED DRUG;

ARTICLE; DRUG OXIDATION; ENZYME ACTIVITY; ENZYME SUBSTRATE COMPLEX; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; LIVER MICROSOME; PRIORITY JOURNAL;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BACULOVIRIDAE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MICROSOMES, LIVER; MIXED FUNCTION OXYGENASES; NICOTINE; OXIDATION-REDUCTION; OXIDOREDUCTASES, N-DEMETHYLATING; RECOMBINANT PROTEINS;

EID: 0032931833     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002040050588     Document Type: Article

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