C-phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 364, Issue 2, 2001, Pages 96-104

  Rimbau, V ^a   Camins, A ^a   Pubill, D ^a   Sureda, F X ^a   Romay, C ^a   Gonzalez R ^a   Jimenez A ^a   Escubedo, E ^a   Camarasa, J ^a   Pallas M ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Apoptosis; C phycocyanin; Cell cycle; Cerebellar granule cells; Flow cytometry; Laser scanning cytometry; Oxidative stress; Rat

Indexed keywords

PHYCOCYANIN; PROPIDIUM IODIDE; SCAVENGER;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CEREBELLUM CORTEX; CONTROLLED STUDY; FLOW CYTOMETRY; GRANULE CELL; INHIBITION KINETICS; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; POTASSIUM DEFICIENCY; RAT;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; CELL CYCLE; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CULTURE MEDIA, SERUM-FREE; NEUROPROTECTIVE AGENTS; PHYCOCYANIN; POTASSIUM CHLORIDE; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES;

EID: 0034910216     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002100100437     Document Type: Article

References (61)

1. Generation of free radicals during lipid hydroperoxide-triggered apoptosis in PC12 cells
2. Pigment epithelium-derived factor (PEDF) differentially protects immature but not mature cerebellar granule cells against apoptotic cell death
3. Removal of serum from primary cultures of cerebellar granule neurons induces oxidative stress and DNA fragmentation: Protection with antioxidants and glutamate receptor antagonists
4. Cytotoxicity of T-2 toxin and its metabolites determined with the neutral red cell viability assay
5. +-induced apoptosis
6. Carnosine protects against excitotoxic cell death independently of effects on reactive oxygen species
7. Apoptosis and increased generation of reactive oxygen species in Down's syndrome neurons in vitro
8. U-83836 prevents kainic acid-induced neuronal damage
9. Tau cleavage and dephosphorylation in cerebellar granule neurons undergoing apoptosis
10. Mitotic signalling by β-amyloid causes neuronal death
11. Activation of cell-cycle-associated proteins in neuronal death: A mandatory or dispensable path?
12. Oxidative stress, glutamate, and neurodegenerative disorders
13. Cellular thiols and reactive oxygen species in drug-induced apoptosis
14. Induction of apoptosis in cerebellar granule neurons by low potassium: Inhibitions of death by insulin-like growth factor I and cAMP
15. Role of oxygen free radicals in cancer development
16. The role of CED-3 related cysteine proteases in apoptosis of cerebellar granule cells
17. Free radicals as mediators of neuronal injury
18. Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: The involvement of intracellular calcium and RNA synthesis
19. Kainate-induced apoptosis in cultured murine cerebellar granule cell elevates expression of the cell cycle gene cyclin D1
20. Anti-inflammatory activity of phycocianin extract in acetic acid-induced colitis in rats
21. Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death
22. Oxidative stress and apoptosis
23. Stimulation of DNA synthesis and proliferation by prostaglandins in primary cultures of adult rat hepatocytes
24. Cancer chemoprevention by tea polyphenols through mitotic signal transduction blockade
25. Kinetics of phycocyanine bilin groups destruction by peroxyl radicals
26. Apoptosis is induced by β-amyloid in cultured central nervous system neurons
27. Effects of antioxidant enzymes in the molecular control of reactive oxygen species toxicology
28. Free radicals, calcium, and the synaptic plasticity-cell death continuum: Emerging roles of the transcriptional factor NFβB
29. Re-entry into the cell cycle: A mechanism for neurodegeneration in Alzheimer disease
30. Aggregation properties of C-phycocyanin from Anacystis nidulans
31. Preventive effect of Ginkgo biloba extract on apoptosis in rat cerebellar neuronal cells induced by hydroxyl radicals
32. The activation of inositol phospholipid hydrolysis as a signal transducing system for excitatory amino acids in primary cultures of cerebellar granule cells
33. Okadaic acid-induced apoptosis in neuronal cells: Evidence for an abortive mitotic attempt
34. Expression of cyclin A decreases during neuronal apoptosis in cultured rat cerebellar granule neurons
35. Cell death during development of the nervous system
36. Role of cell cycle proteins in cerebellar granule neuron apoptosis
37. 1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis
38. Multiple pathways of neuronal death induced by DNA-damaging agents, NGF deprivation, and oxidative stress
39. Neuronal cell death
40. Evidence for apoptotic cell death in Huntington disease and exci-totoxic animal models
41. Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from apoptotic gene to a proapoptotic gene: Studies in yeast and neural cells
42. Mitochondria, oxygen free radicals, disease and aging
43. Oxidative damage in the central nervous system: Protection by melatonin
44. Protective effects of C-phycocyanin against kainic acid-induced neuronal damage in rat hippocampus
45. Further studies on anti-inflammatory activity of C-phycocyanin in some animal models of inflammation
46. Antioxidant and anti-inflammatory properties of C-phycocyanin from blue-green algae
47. 4 levels in arachidonic acid-induced mouse ear inflammation test
48. Up-regulation of cyclin D1 occurs in apoptosis of immature but not mature cerebellar granule neurons in culture
49. Apoptosis and the nervous system
50. Potassium deprivation-induced apoptosis of cerebellar granule neurons: A sequential requirement for new mRNA and protein synthesis, ICE-like protease activity, and reactive oxygen species
51. Oxidative stress in neurodegener-ative diseases
52. Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: Selective involvement of phosphoinositol 3-kinase and the mitogen-activated protein kinase pathway
53. Oxidative stress and neurodegenerative disorders
54. Reactive oxygen production by glutamate agonists in dissociated cerebellar cells: A flow cytometric study
55. The regulation of reactive oxygen species production during programmed cell death
56. 2+ fit in?
57. Hepatoprotective effect of C-phycocyanin: Protection for carbon tetrachloride and R-(+)-pulegone-mediated hepatotoxicity in rats
58. Adenosine and ADP prevent apoptosis in cultured rat cerebellar granule cells
59. Prevention of PC12 cell death by N-acetylcysteine requires activation of the ras pathway
60. Activation of oncogenic pathways in degenerating neurons in Alzheimer's disease