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Volumn 18, Issue 6, 1998, Pages 667-682

Free radicals as mediators of neuronal injury

Author keywords

Excitotoxicity; Glutamate; Hydroxyl radical; Nitric oxide; Peroxynitrite; Reactive oxygen species; Superoxide anion

Indexed keywords

CALCIUM ION; COPPER ZINC SUPEROXIDE DISMUTASE; FREE RADICAL; NITRIC OXIDE; SUPEROXIDE;

EID: 0032440899     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1020221919154     Document Type: Review
Times cited : (265)

References (126)
  • 1
    • 0023069259 scopus 로고
    • ADP-ribosylation of proteins: Enzymology and biological significance
    • Springer-Verlag, New York
    • Althaus, F. R., and Richer, C. (1987). ADP-ribosylation of proteins: enzymology and biological significance. In Molecular Biology, Biochemistry and Biophysics, Vol. 37, Springer-Verlag, New York, pp. 1-125.
    • (1987) Molecular Biology, Biochemistry and Biophysics , vol.37 , pp. 1-125
    • Althaus, F.R.1    Richer, C.2
  • 2
    • 0025288494 scopus 로고
    • Hypoxia prevents seizures and neural damage of the hippocampus induced by kainic acid in rats
    • Amano, S., Toshiyuki, O., Fumitada, H., Nishizawa, K., and Morimi, S. (1990). Hypoxia prevents seizures and neural damage of the hippocampus induced by kainic acid in rats. Brain Res. 523:121-126.
    • (1990) Brain Res. , vol.523 , pp. 121-126
    • Amano, S.1    Toshiyuki, O.2    Fumitada, H.3    Nishizawa, K.4    Morimi, S.5
  • 3
    • 0023144940 scopus 로고
    • Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl radical generation?
    • Aruoma, O. I., and Halliwell, B. (1987). Superoxide-dependent and ascorbate-dependent formation of hydroxyl radicals from hydrogen peroxide in the presence of iron. Are lactoferrin and transferrin promoters of hydroxyl radical generation? Biochem. J. 241:273-278.
    • (1987) Biochem. J. , vol.241 , pp. 273-278
    • Aruoma, O.I.1    Halliwell, B.2
  • 5
    • 0023220462 scopus 로고
    • Effect of mannitol treatment on brain neurotransmitter markers in kainic acid induced epilepsy
    • Baran, H., Lassman, H., Sperk, G., Seitelberger, F., and Hornykiewicz, O. (1987). Effect of mannitol treatment on brain neurotransmitter markers in kainic acid induced epilepsy. Neuroscience 21:679-684.
    • (1987) Neuroscience , vol.21 , pp. 679-684
    • Baran, H.1    Lassman, H.2    Sperk, G.3    Seitelberger, F.4    Hornykiewicz, O.5
  • 6
    • 0029043583 scopus 로고
    • Excitotoxic increase of xanthine dehydrogenase and xanthin oxidase in the rat olfactory cortex
    • Battelli, M. G., Bonamici, L., Abbondanza, A., Virgili, M., Contestabile, A., and Stirpe, F. (1995). Excitotoxic increase of xanthine dehydrogenase and xanthin oxidase in the rat olfactory cortex. Brain Res. 86:340-344.
    • (1995) Brain Res. , vol.86 , pp. 340-344
    • Battelli, M.G.1    Bonamici, L.2    Abbondanza, A.3    Virgili, M.4    Contestabile, A.5    Stirpe, F.6
  • 7
    • 0028641246 scopus 로고
    • Peroxynitrite versus hydroxyl radical: The role of nitric oxide in superoxide-dependent cerebral injury
    • Beckman, J. S. (1994). Peroxynitrite versus hydroxyl radical: The role of nitric oxide in superoxide-dependent cerebral injury. Ann. N.Y. Acad. Sci. 738:69-75.
    • (1994) Ann. N.Y. Acad. Sci. , vol.738 , pp. 69-75
    • Beckman, J.S.1
  • 10
    • 0023786731 scopus 로고
    • Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide
    • Brenneman, D. E., Westbrook, G. L., Fitzgerald, S. P., Ennist, D. L., Elkins, K. L., Ruff, M. R., and Pert, C. B. (1988). Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide. Nature 335:639-642.
    • (1988) Nature , vol.335 , pp. 639-642
    • Brenneman, D.E.1    Westbrook, G.L.2    Fitzgerald, S.P.3    Ennist, D.L.4    Elkins, K.L.5    Ruff, M.R.6    Pert, C.B.7
  • 11
  • 12
    • 0026702955 scopus 로고
    • Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death
    • Boje, K. M., and Arora, P. K. (1992). Microglial-produced nitric oxide and reactive nitrogen oxides mediate neuronal cell death. Brain Res. 587:250-256.
    • (1992) Brain Res. , vol.587 , pp. 250-256
    • Boje, K.M.1    Arora, P.K.2
  • 13
    • 0028145462 scopus 로고
    • Nitric-oxide mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes
    • Bolanos, J. P., Peuchen, S., Heales, S. J., Land, J. M., and Clark, J. B. (1994). Nitric-oxide mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes. J. Neurochem. 63:910-916.
    • (1994) J. Neurochem. , vol.63 , pp. 910-916
    • Bolanos, J.P.1    Peuchen, S.2    Heales, S.J.3    Land, J.M.4    Clark, J.B.5
  • 14
    • 0027251608 scopus 로고
    • Oxidative stress induced by glutamate receptor agonists
    • Bondy, S. C., and Lee, D. K. (1993). Oxidative stress induced by glutamate receptor agonists. Brain Res. 610:229-233.
    • (1993) Brain Res. , vol.610 , pp. 229-233
    • Bondy, S.C.1    Lee, D.K.2
  • 15
    • 0028966205 scopus 로고
    • Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: Implications for HIV-associated neurological disease
    • Bukrinsky, M. I., Nottet, H. S., Schmidtmayerova, H., Dubrovsky, L., Flanagan, C. R., Mullins, M. E., Lipton, S. A., and Gendelman, H. E. (1995). Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease. J. Exp. Med. 181:735-745.
    • (1995) J. Exp. Med. , vol.181 , pp. 735-745
    • Bukrinsky, M.I.1    Nottet, H.S.2    Schmidtmayerova, H.3    Dubrovsky, L.4    Flanagan, C.R.5    Mullins, M.E.6    Lipton, S.A.7    Gendelman, H.E.8
  • 16
    • 0028181788 scopus 로고
    • Neuroprotective efficacy of N-omega-nitro-L-arginine after focal cerebral ischemia in the mouse and inhibition of cortical nitric oxide synthase
    • Carreau, A., Duval, D., Poignet, H., Scatton, B., Vige, X., and Nowicki, J. P. (1994). Neuroprotective efficacy of N-omega-nitro-L-arginine after focal cerebral ischemia in the mouse and inhibition of cortical nitric oxide synthase. Eur. J. Pharmacol. 256:241-249.
    • (1994) Eur. J. Pharmacol. , vol.256 , pp. 241-249
    • Carreau, A.1    Duval, D.2    Poignet, H.3    Scatton, B.4    Vige, X.5    Nowicki, J.P.6
  • 17
    • 0027395008 scopus 로고
    • Superoxide and nitric oxide cooperation in hypoxia/reoxygenation-induced neuron injury
    • Cazevieille, C., Muller, A., Meynier, F., and Bonne, C. (1993). Superoxide and nitric oxide cooperation in hypoxia/reoxygenation-induced neuron injury. Free Radical Biol. Med. 14:389-395.
    • (1993) Free Radical Biol. Med. , vol.14 , pp. 389-395
    • Cazevieille, C.1    Muller, A.2    Meynier, F.3    Bonne, C.4
  • 18
    • 0025513984 scopus 로고
    • Reduced neurotoxicity in transgenic mice overexpressing human copper-zinc-superoxide dismutase
    • Chan, P. H., Chu, L., Chen, S. F., Carlson, E. J., and Epstein, C. J. (1990). Reduced neurotoxicity in transgenic mice overexpressing human copper-zinc-superoxide dismutase. Stroke 21 (Suppl III):80-82.
    • (1990) Stroke , vol.21 , Issue.3 SUPPL. , pp. 80-82
    • Chan, P.H.1    Chu, L.2    Chen, S.F.3    Carlson, E.J.4    Epstein, C.J.5
  • 20
    • 0026738695 scopus 로고
    • Activated microglia mediate cell injury via a nitric oxide mechanism
    • Chao, C. C., Hu, S., Molitor, T. W., Shaskan, E. G., and Peterson, P. K. (1992). Activated microglia mediate cell injury via a nitric oxide mechanism. J. Immun. 149:2736-2741.
    • (1992) J. Immun. , vol.149 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskan, E.G.4    Peterson, P.K.5
  • 21
    • 0027946642 scopus 로고
    • Oxidative mechanisms involved in kainate-induced cytotoxicity in cortical neurons
    • Cheng, Y., and Sun, A. Y. (1994). Oxidative mechanisms involved in kainate-induced cytotoxicity in cortical neurons. Neurochem. Res. 19:1557-1564.
    • (1994) Neurochem. Res. , vol.19 , pp. 1557-1564
    • Cheng, Y.1    Sun, A.Y.2
  • 22
    • 0024093449 scopus 로고
    • Glutamate neurotoxicity and diseases of the nervous system
    • Choi, D. W. (1988). Glutamate neurotoxicity and diseases of the nervous system. Neuron 1:623-634.
    • (1988) Neuron , vol.1 , pp. 623-634
    • Choi, D.W.1
  • 23
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi, D. W. (1992). Excitotoxic cell death. J. Neurobiol. 23:1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 24
    • 0030597992 scopus 로고    scopus 로고
    • Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons
    • Ciani, E., Groneng, L., Voltattorni, M., Rolseth, V., Constestabile, A., and Paulsen, R. E. (1996). Inhibition of free radical production or free radical scavenging protects from the excitotoxic cell death mediated by glutamate in cultures of cerebellar granule neurons. Brain Res. 728:1-6.
    • (1996) Brain Res. , vol.728 , pp. 1-6
    • Ciani, E.1    Groneng, L.2    Voltattorni, M.3    Rolseth, V.4    Constestabile, A.5    Paulsen, R.E.6
  • 25
    • 0026471695 scopus 로고
    • Evidence that CHP100 neuroblastoma cell death induced by N-methyl-D-aspartate involves L-arginine-nitric oxide pathway activation
    • Corasaniti, M., Tartaglia, R. L., Melino, G., Nistico, G., and Finazzi-Agro, A. (1992). Evidence that CHP100 neuroblastoma cell death induced by N-methyl-D-aspartate involves L-arginine-nitric oxide pathway activation. Neurosci. Lett. 147:221-223.
    • (1992) Neurosci. Lett. , vol.147 , pp. 221-223
    • Corasaniti, M.1    Tartaglia, R.L.2    Melino, G.3    Nistico, G.4    Finazzi-Agro, A.5
  • 26
    • 0027990790 scopus 로고
    • Poly(ADP-ribose) polymerase: Early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells
    • Cosi, C., Suzuki, H., Milani, D., Menegazzi, M., Vantini, G., Kanai, Y., and Skaper, S. D. (1994). Poly(ADP-ribose) polymerase: Early involvement in glutamate-induced neurotoxicity in cultured cerebellar granule cells. J. Neurosci. Res. 39:38-46.
    • (1994) J. Neurosci. Res. , vol.39 , pp. 38-46
    • Cosi, C.1    Suzuki, H.2    Milani, D.3    Menegazzi, M.4    Vantini, G.5    Kanai, Y.6    Skaper, S.D.7
  • 27
    • 0027686249 scopus 로고
    • Oxidative stress, glutamate, and neurodegenerative disorders
    • Coyle, J. P., and Puttfarcken, P. S. (1993). Oxidative stress, glutamate, and neurodegenerative disorders. Science 262:689-695.
    • (1993) Science , vol.262 , pp. 689-695
    • Coyle, J.P.1    Puttfarcken, P.S.2
  • 28
    • 0029353191 scopus 로고
    • Wilson's disease: A new gene and an animal model for an old disease
    • Cuthbert (1995). Wilson's disease: A new gene and an animal model for an old disease. J. Invest. Med. 43:323-336.
    • (1995) J. Invest. Med. , vol.43 , pp. 323-336
    • Cuthbert1
  • 29
    • 0023655050 scopus 로고
    • Proteins damaged by oxygen radicals are rapidly degraded in extracts of red blood cells
    • Davies, K. J. A., and Goldberg, A. L. (1987). Proteins damaged by oxygen radicals are rapidly degraded in extracts of red blood cells. J. Biol. Chem. 262:8227-8234.
    • (1987) J. Biol. Chem. , vol.262 , pp. 8227-8234
    • Davies, K.J.A.1    Goldberg, A.L.2
  • 30
    • 0028674890 scopus 로고
    • Nitric oxide and focal cerebral ischemia: Multiplicity of actions and diverse outcome
    • Dawson, D. A. (1994). Nitric oxide and focal cerebral ischemia: Multiplicity of actions and diverse outcome. Cerebrovasc. Brain Metab. Rev. 6:299-324.
    • (1994) Cerebrovasc. Brain Metab. Rev. , vol.6 , pp. 299-324
    • Dawson, D.A.1
  • 31
    • 0028954988 scopus 로고
    • ADP-ribosylation as a mechanism for the action of nitric oxide in the nervous system
    • Dawson, T. M., and Dawson, V. L. (1995). ADP-ribosylation as a mechanism for the action of nitric oxide in the nervous system. New Horiz. 3:85-92.
    • (1995) New Horiz. , vol.3 , pp. 85-92
    • Dawson, T.M.1    Dawson, V.L.2
  • 32
    • 0027939807 scopus 로고
    • Gases as biological messengers: Nitric oxide and carbon monoxide in the brain
    • Dawson, T. M., and Snyder, S. H. (1994). Gases as biological messengers: Nitric oxide and carbon monoxide in the brain. J. Neurosci. 14:5147-5149.
    • (1994) J. Neurosci. , vol.14 , pp. 5147-5149
    • Dawson, T.M.1    Snyder, S.H.2
  • 33
    • 0027453536 scopus 로고
    • Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity
    • Dawson, T. M., Steiner, J. P., Dawson, V. L., Dinerman, J. L., Uhl, G. R., and Snyder, S. H. (1993). Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proc. Natl. Acad. Sci. USA 90:9808-9812.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 9808-9812
    • Dawson, T.M.1    Steiner, J.P.2    Dawson, V.L.3    Dinerman, J.L.4    Uhl, G.R.5    Snyder, S.H.6
  • 34
    • 0028928579 scopus 로고
    • Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase
    • Dawson, T. M., Hung, K., Dawson, V. L., Steiner, J. P., and Snyder, S. H. (1995). Neuroprotective effects of gangliosides may involve inhibition of nitric oxide synthase. Ann. Neurol. 37:115-118.
    • (1995) Ann. Neurol. , vol.37 , pp. 115-118
    • Dawson, T.M.1    Hung, K.2    Dawson, V.L.3    Steiner, J.P.4    Snyder, S.H.5
  • 37
    • 0027480439 scopus 로고
    • Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures
    • Dawson, V. L., Dawson, T. M., Uhl, G. R., and Snyder, S. H. (1993a). Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. Proc. Natl. Acad. Sci. USA 90:3256-3259.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 3256-3259
    • Dawson, V.L.1    Dawson, T.M.2    Uhl, G.R.3    Snyder, S.H.4
  • 38
    • 0027178135 scopus 로고
    • Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures
    • Dawson, V. L., Dawson, T. M., Bartley, D. A., Uhl, G. R., and Snyder, S. H. (1993b). Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. J. Neurosci. 13:2651-2661.
    • (1993) J. Neurosci. , vol.13 , pp. 2651-2661
    • Dawson, V.L.1    Dawson, T.M.2    Bartley, D.A.3    Uhl, G.R.4    Snyder, S.H.5
  • 39
    • 0028089896 scopus 로고
    • Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures
    • Dawson, V. L., Brahmbhatt, H. P., Mong, J. A., and Dawson, T. M. (1994). Expression of inducible nitric oxide synthase causes delayed neurotoxicity in primary mixed neuronal-glial cortical cultures. Neuropharmacology 33:1425-1430.
    • (1994) Neuropharmacology , vol.33 , pp. 1425-1430
    • Dawson, V.L.1    Brahmbhatt, H.P.2    Mong, J.A.3    Dawson, T.M.4
  • 40
    • 0029927787 scopus 로고    scopus 로고
    • Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase deficient mice
    • Dawson, V. L., Kizushi, V. M., Huang, P. L., Snyder, S. H., and Dawson, T. M. (1996). Resistance to neurotoxicity in cortical cultures from neuronal nitric oxide synthase deficient mice. J. Neurosci. 16:2479-2487.
    • (1996) J. Neurosci. , vol.16 , pp. 2479-2487
    • Dawson, V.L.1    Kizushi, V.M.2    Huang, P.L.3    Snyder, S.H.4    Dawson, T.M.5
  • 42
    • 0015298096 scopus 로고
    • The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (Type D) into oxidase (Type O) and purification of the enzyme
    • Della Corte, E., and Stirpe, F. (1972). The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (Type D) into oxidase (Type O) and purification of the enzyme. Biochem. J. 126:739-745.
    • (1972) Biochem. J. , vol.126 , pp. 739-745
    • Della Corte, E.1    Stirpe, F.2
  • 44
    • 0026704075 scopus 로고
    • Alterations of levels of iron, ferritin and other trace metals in neurodegenerative diseases affecting the basal ganglia
    • Dexter, D. T., Jenner, P., Schapira, A. H. V., and Marsden, C. D. (1992). Alterations of levels of iron, ferritin and other trace metals in neurodegenerative diseases affecting the basal ganglia. Ann. Neurol. 32(Suppl.):94-100.
    • (1992) Ann. Neurol. , vol.32 , Issue.SUPPL. , pp. 94-100
    • Dexter, D.T.1    Jenner, P.2    Schapira, A.H.V.3    Marsden, C.D.4
  • 45
    • 0025278342 scopus 로고
    • HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists
    • Dreyer, E. B., Kaiser, P. K., Offermann, J. T., and Lipton, S. A. (1990). HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science 248:364-367.
    • (1990) Science , vol.248 , pp. 364-367
    • Dreyer, E.B.1    Kaiser, P.K.2    Offermann, J.T.3    Lipton, S.A.4
  • 46
    • 0028232804 scopus 로고
    • Excitotoxicity, free radicals and cell membrane changes
    • Dugan, I. L., and Choi, D. W. (1994). Excitotoxicity, free radicals and cell membrane changes. Ann. Neurol. 35:517-521.
    • (1994) Ann. Neurol. , vol.35 , pp. 517-521
    • Dugan, I.L.1    Choi, D.W.2
  • 47
    • 0023197336 scopus 로고
    • Mechanisms of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury
    • Dykens, J. A., Stern, A., and Trenkner, E. (1987). Mechanisms of kainate toxicity to cerebellar neurons in vitro is analogous to reperfusion tissue injury. J. Neurochem. 49:1222-1228.
    • (1987) J. Neurochem. , vol.49 , pp. 1222-1228
    • Dykens, J.A.1    Stern, A.2    Trenkner, E.3
  • 48
    • 0027933701 scopus 로고
    • +: Implications for neurodegeneration
    • +: Implications for neurodegeneration. J. Neurochem. 63:584-591.
    • (1994) J. Neurochem. , vol.63 , pp. 584-591
    • Dykens, J.A.1
  • 50
    • 0027265381 scopus 로고
    • Free radicals in brain metabolism and pathology
    • Evans, P. H. (1993). Free radicals in brain metabolism and pathology. Br. Med. Bull. 49:577-587.
    • (1993) Br. Med. Bull. , vol.49 , pp. 577-587
    • Evans, P.H.1
  • 51
    • 0012053105 scopus 로고
    • Neurochemical evaluation of the protective effects of mannitol and alpha-tocopherol in rats injected intra striatally with kainic acid
    • Facchinetti, F., and Contestabile, A. (1993). Neurochemical evaluation of the protective effects of mannitol and alpha-tocopherol in rats injected intra striatally with kainic acid. Neurodegeneration 2:123-127.
    • (1993) Neurodegeneration , vol.2 , pp. 123-127
    • Facchinetti, F.1    Contestabile, A.2
  • 52
    • 0026667538 scopus 로고
    • Antagonists of the NMDA receptor and allopurinol protect the olfactory cortex but not the striatum after intracerebral injection of kainic acid
    • Facchinetti, F., Virgili, M., Contestabile, A., and Barnabei, O. (1992). Antagonists of the NMDA receptor and allopurinol protect the olfactory cortex but not the striatum after intracerebral injection of kainic acid. Brain Res. 585:330-334.
    • (1992) Brain Res. , vol.585 , pp. 330-334
    • Facchinetti, F.1    Virgili, M.2    Contestabile, A.3    Barnabei, O.4
  • 53
    • 0029065856 scopus 로고
    • Involvement of divalent ions in the nitric oxide-induced blockade of N-methyl-D-aspartate receptors in cerebllar granule cells
    • Fagni, L., Olivier, M., Lafoncazal, M., and Bockaert, J. (1995). Involvement of divalent ions in the nitric oxide-induced blockade of N-methyl-D-aspartate receptors in cerebllar granule cells. Mol. Pharmacol. 47:1239-1247.
    • (1995) Mol. Pharmacol. , vol.47 , pp. 1239-1247
    • Fagni, L.1    Olivier, M.2    Lafoncazal, M.3    Bockaert, J.4
  • 54
    • 0023080626 scopus 로고
    • Morphologic and histochemical characteristics of a spared subset of striatal neurons in Huntington's disease
    • Ferrante, R. J., Kowall, N. W., Beal, M. F., Martin, J. B., and Richardson, E. P., Jr (1987). Morphologic and histochemical characteristics of a spared subset of striatal neurons in Huntington's disease. J. Neuropathol. Exp. Neurol. 46:12-27.
    • (1987) J. Neuropathol. Exp. Neurol. , vol.46 , pp. 12-27
    • Ferrante, R.J.1    Kowall, N.W.2    Beal, M.F.3    Martin, J.B.4    Richardson Jr., E.P.5
  • 55
    • 0027329929 scopus 로고
    • Effects of dopaminergic drugs on superoxide dismutase: Implications for senescence
    • Glover, V., Clow, A., and Sandler, M. (1993). Effects of dopaminergic drugs on superoxide dismutase: Implications for senescence. J. Neural Transm. Suppl. 40:37-45.
    • (1993) J. Neural Transm. Suppl. , vol.40 , pp. 37-45
    • Glover, V.1    Clow, A.2    Sandler, M.3
  • 56
    • 0027937548 scopus 로고
    • Oxidative stress: Free radical production in neural degeneration
    • Gotz, M. E., Kunig, G., Riederer, P., and Youdim, M. B. H. (1994). Oxidative stress: Free radical production in neural degeneration. Pharmacol. Ther. 63:37-122.
    • (1994) Pharmacol. Ther. , vol.63 , pp. 37-122
    • Gotz, M.E.1    Kunig, G.2    Riederer, P.3    Youdim, M.B.H.4
  • 58
    • 0026754574 scopus 로고
    • Reactive oxygen species and the central nervous system
    • Halliwell, B. (1992). Reactive oxygen species and the central nervous system. J. Neurochem. 59:1609-1623.
    • (1992) J. Neurochem. , vol.59 , pp. 1609-1623
    • Halliwell, B.1
  • 59
    • 0021329973 scopus 로고
    • The regional distribution and cellular localization of iron in the rat brain
    • Hill, J. M., and Switzer, R. C., III (1984). The regional distribution and cellular localization of iron in the rat brain. Neuroscience 3:595-603.
    • (1984) Neuroscience , vol.3 , pp. 595-603
    • Hill, J.M.1    Switzer III, R.C.2
  • 61
  • 62
    • 0026480838 scopus 로고
    • Relative sparing of nitric oxide synthase-containing neurons in the hippocampal formation in Alzheimer's disease
    • Hyman, B. T., Marzloff, K., Wenniger, J. J., Dawson, T. M., Bredt, D. S., and Snyder, S. H. (1992). Relative sparing of nitric oxide synthase-containing neurons in the hippocampal formation in Alzheimer's disease. Ann Neurol. 32:818-820.
    • (1992) Ann Neurol. , vol.32 , pp. 818-820
    • Hyman, B.T.1    Marzloff, K.2    Wenniger, J.J.3    Dawson, T.M.4    Bredt, D.S.5    Snyder, S.H.6
  • 63
    • 0028894427 scopus 로고
    • Marked induction of calcium-independent nitric oxide synthase activity after focal cerebral ischemia
    • Iadecola, C., Xu, X., Zhang, F., El-Fakahany, E. E., and Ross, M. E. (1995a). Marked induction of calcium-independent nitric oxide synthase activity after focal cerebral ischemia. J. Cereb. Blood Flow Metab. 15:52-59.
    • (1995) J. Cereb. Blood Flow Metab. , vol.15 , pp. 52-59
    • Iadecola, C.1    Xu, X.2    Zhang, F.3    El-Fakahany, E.E.4    Ross, M.E.5
  • 64
    • 0028891572 scopus 로고
    • Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage
    • Iadecola, C., Zhang, F., and Xu, X. (1995b). Inhibition of inducible nitric oxide synthase ameliorates cerebral ischemic damage. Am. J. Physiol. 268:R286-R292.
    • (1995) Am. J. Physiol. , vol.268
    • Iadecola, C.1    Zhang, F.2    Xu, X.3
  • 65
    • 0024514717 scopus 로고
    • Enhancement by catechols of hydroxyl radical formation in the presence of ferric ions and hydrogen peroxide
    • Iwahashi, H., Morishita, H., Ishii, T., Sugata, R., and Kido, R. (1989). Enhancement by catechols of hydroxyl radical formation in the presence of ferric ions and hydrogen peroxide. J. Biochem. 105:429-434.
    • (1989) J. Biochem. , vol.105 , pp. 429-434
    • Iwahashi, H.1    Morishita, H.2    Ishii, T.3    Sugata, R.4    Kido, R.5
  • 66
    • 0026501674 scopus 로고
    • Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices
    • Izumi, Y., Benz, A. M., Clifford, D. B., and Zorumski, C. F. (1992). Nitric oxide inhibitors attenuate N-methyl-D-aspartate excitotoxicity in rat hippocampal slices. Neurosci. Lett. 135:227-230.
    • (1992) Neurosci. Lett. , vol.135 , pp. 227-230
    • Izumi, Y.1    Benz, A.M.2    Clifford, D.B.3    Zorumski, C.F.4
  • 68
    • 0029084424 scopus 로고
    • Arachidonic acid as a neurotoxic and neurotrophic substance
    • Katsuki, H., and Okuda, S. (1995). Arachidonic acid as a neurotoxic and neurotrophic substance. Prog. Neurobiol. 46:607-636.
    • (1995) Prog. Neurobiol. , vol.46 , pp. 607-636
    • Katsuki, H.1    Okuda, S.2
  • 69
    • 0026345023 scopus 로고
    • Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase
    • Kinouchi, H., Epstein, C. J., Mizui, T., Carlson, E., Chen, S. F., and Chan, P. H. (1991). Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase. Proc. Natl. Acad. Sci. USA 88:11158-11162.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 11158-11162
    • Kinouchi, H.1    Epstein, C.J.2    Mizui, T.3    Carlson, E.4    Chen, S.F.5    Chan, P.H.6
  • 70
    • 0027154715 scopus 로고
    • Lesion-induced NADPH-diaphorase reactivity in neocortical pyramidal neurons
    • Kitchener, P. O., Van der Zee, C., and Diamond, J. (1993). Lesion-induced NADPH-diaphorase reactivity in neocortical pyramidal neurons. Neuroreport 4:487-490.
    • (1993) Neuroreport , vol.4 , pp. 487-490
    • Kitchener, P.O.1    Van Der Zee, C.2    Diamond, J.3
  • 71
    • 0023897857 scopus 로고
    • Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists
    • Koh, J. Y., and Choi, D. W. (1988). Cultured striatal neurons containing NADPH-diaphorase or acetylcholinesterase are selectively resistant to injury by NMDA receptor agonists. Brain Res. 446:374-378.
    • (1988) Brain Res. , vol.446 , pp. 374-378
    • Koh, J.Y.1    Choi, D.W.2
  • 72
    • 0028961853 scopus 로고
    • The mapping of HIV-1 gp160 epitopes required for interleukin-1 and tumor necrosis factor alpha production in glial cells
    • Koka, P., He, K., Camerini, D., Tran, T., Yashar, S. S., and Merrill, J. E. (1995). The mapping of HIV-1 gp160 epitopes required for interleukin-1 and tumor necrosis factor alpha production in glial cells. J. Neuroimmunol. 57:179-191.
    • (1995) J. Neuroimmunol. , vol.57 , pp. 179-191
    • Koka, P.1    He, K.2    Camerini, D.3    Tran, T.4    Yashar, S.S.5    Merrill, J.E.6
  • 73
    • 0027519170 scopus 로고
    • Reduction of striatal N-methyl-D-aspartate toxicity by inhibition of nitric oxide synthase
    • Kollegger, H., McBean, G. J., and Tipton, K. F. (1993). Reduction of striatal N-methyl-D-aspartate toxicity by inhibition of nitric oxide synthase. Biochem. Pharmacol. 45:260-264.
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 260-264
    • Kollegger, H.1    McBean, G.J.2    Tipton, K.F.3
  • 74
    • 0024785709 scopus 로고
    • Oxygen radicals in CNS damage
    • Kontos, H. A. (1989). Oxygen radicals in CNS damage. Chem. Biol. Interact. 72:229-255.
    • (1989) Chem. Biol. Interact. , vol.72 , pp. 229-255
    • Kontos, H.A.1
  • 75
    • 0027221998 scopus 로고
    • NMDA-dependent superoxide production and neurotoxicity
    • Lafon-Cazal, M., Pietri, S., Culcasi, M., and Bockaert, J. (1993). NMDA-dependent superoxide production and neurotoxicity. Nature 364:535-537.
    • (1993) Nature , vol.364 , pp. 535-537
    • Lafon-Cazal, M.1    Pietri, S.2    Culcasi, M.3    Bockaert, J.4
  • 76
    • 0020680904 scopus 로고
    • Chronic parkinsonism in human due to a product of meperidine-analog synthesis
    • Langston, J. W., Ballard, P. A., Tetrud, J. W., and Irwin, I. (1983). Chronic parkinsonism in human due to a product of meperidine-analog synthesis. Science 219:979-980.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.A.2    Tetrud, J.W.3    Irwin, I.4
  • 77
    • 0026632865 scopus 로고
    • Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex
    • Lei, S. Z., Pan, Z. H., Aggarwal, S. K., Chen, H. S. V., Hartman, J., Sucher, N. J., and Lipton, S. A. (1992). Effect of nitric oxide production on the redox modulatory site of the NMDA receptor-channel complex. Neuron 8:1087-1099.
    • (1992) Neuron , vol.8 , pp. 1087-1099
    • Lei, S.Z.1    Pan, Z.H.2    Aggarwal, S.K.3    Chen, H.S.V.4    Hartman, J.5    Sucher, N.J.6    Lipton, S.A.7
  • 78
    • 0025866327 scopus 로고
    • Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity
    • Lipton, S. A., Sucher, N. J., Kaiser, P. K., and Dreyer, E. B. (1991). Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity. Neuron 7:111-118.
    • (1991) Neuron , vol.7 , pp. 111-118
    • Lipton, S.A.1    Sucher, N.J.2    Kaiser, P.K.3    Dreyer, E.B.4
  • 79
    • 0026568069 scopus 로고
    • Ethanol and excitotoxicity in cultured cortical neurons: Differential sensitivity to N-methyl-D-aspartate and sodium nitroprusside toxicity
    • Lustig, H. S., von Brauchitsch, K. L., Chan, J., and Greenberg, D. A. (1992). Ethanol and excitotoxicity in cultured cortical neurons: Differential sensitivity to N-methyl-D-aspartate and sodium nitroprusside toxicity. J. Neurochem. 577:343-346.
    • (1992) J. Neurochem. , vol.577 , pp. 343-346
    • Lustig, H.S.1    Von Brauchitsch, K.L.2    Chan, J.3    Greenberg, D.A.4
  • 80
    • 0027245908 scopus 로고
    • Nitric oxide measured by a porphyrinuric micro sensor in rat brain after transient middle cerebral artery occlusion
    • Malinski, T., Bailey, F., Zhang, Z. G., and Chopp, M. (1993). Nitric oxide measured by a porphyrinuric micro sensor in rat brain after transient middle cerebral artery occlusion. J. Cereb. Blood Flow. Metab. 13:355-358.
    • (1993) J. Cereb. Blood Flow. Metab. , vol.13 , pp. 355-358
    • Malinski, T.1    Bailey, F.2    Zhang, Z.G.3    Chopp, M.4
  • 81
    • 0021776272 scopus 로고
    • Vitamin E: Interactions with free radicals and ascorbate
    • McCay, P. B. (1985). Vitamin E: interactions with free radicals and ascorbate. Annu. Rev. Neurol. 5:323-340.
    • (1985) Annu. Rev. Neurol. , vol.5 , pp. 323-340
    • McCay, P.B.1
  • 82
    • 0002756987 scopus 로고
    • Possible role of vitamin e as a free radical scavenger and singlet oxygen quencher in biological systems which initiate radical mediated reactions
    • Duve, C. D., and Hayaishi, O. (eds.), Elsevier, North-Holland Biomedical Press, Amsterdam
    • McCay, P. B., Fong, K. L., Lai, E. K., and King, M. M. (1978). Possible role of vitamin E as a free radical scavenger and singlet oxygen quencher in biological systems which initiate radical mediated reactions. In Duve, C. D., and Hayaishi, O. (eds.), Tocopherol, Oxygen and Biomembranes, Elsevier, North-Holland Biomedical Press, Amsterdam, pp. 41-57.
    • (1978) Tocopherol, Oxygen and Biomembranes , pp. 41-57
    • McCay, P.B.1    Fong, K.L.2    Lai, E.K.3    King, M.M.4
  • 83
    • 0025063609 scopus 로고
    • Excitatory amino acid neurotoxicity and neurodegenerative disease
    • Meldrum, B., and Garthwaite, J. (1990). Excitatory amino acid neurotoxicity and neurodegenerative disease. Trends Pharmacol. Sci. 11:379-387.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 379-387
    • Meldrum, B.1    Garthwaite, J.2
  • 84
    • 0027161216 scopus 로고
    • Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide
    • Merrill, J. E., Ignarro, L. J., Sherman, M. P., Melinek, J., and Lane, T. E. (1993). Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide. J. Immunol. 151:2132-2141.
    • (1993) J. Immunol. , vol.151 , pp. 2132-2141
    • Merrill, J.E.1    Ignarro, L.J.2    Sherman, M.P.3    Melinek, J.4    Lane, T.E.5
  • 85
    • 0028365824 scopus 로고
    • Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine
    • Minc-Golomb, D., Tsarfaty, I., and Schwartz, J. P. (1994). Expression of inducible nitric oxide synthase by neurones following exposure to endotoxin and cytokine. Br. J. Pharmacol. 112:720-722.
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 720-722
    • Minc-Golomb, D.1    Tsarfaty, I.2    Schwartz, J.P.3
  • 87
    • 0024997540 scopus 로고
    • 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures
    • Monyer, H., Hartley, D. M., and Choi, D. W. (1990). 21-Aminosteroids attenuate excitotoxic neuronal injury in cortical cell cultures. Neuron 5:121-126.
    • (1990) Neuron , vol.5 , pp. 121-126
    • Monyer, H.1    Hartley, D.M.2    Choi, D.W.3
  • 90
    • 0028171387 scopus 로고
    • The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex
    • O'Regan, M. H., Smith-Barbour, M., Perkins, L. M., Cao, X., and Phillis, J. W. (1994). The effect of amflutizole, a xanthine oxidase inhibitor, on ischemia-evoked purine release and free radical formation in the rat cerebral cortex. Neuropharmacology 33:1197-1201.
    • (1994) Neuropharmacology , vol.33 , pp. 1197-1201
    • O'Regan, M.H.1    Smith-Barbour, M.2    Perkins, L.M.3    Cao, X.4    Phillis, J.W.5
  • 91
    • 0025967365 scopus 로고
    • Vitamin C, newer insights into its biochemical functions
    • Padh, H. (1991). Vitamin C, newer insights into its biochemical functions. Nutr. Rev. 49:65-70.
    • (1991) Nutr. Rev. , vol.49 , pp. 65-70
    • Padh, H.1
  • 92
    • 6544283168 scopus 로고
    • Excitatory amino acid release from rat hippocampal slices as a consequence of free radical formation
    • Pellegrini-Giampietro, D. E., Cherici, G., Alesiani, M., Carla, V., and Moroni, F. (1988). Excitatory amino acid release from rat hippocampal slices as a consequence of free radical formation. Brain Res. 676:205-211.
    • (1988) Brain Res. , vol.676 , pp. 205-211
    • Pellegrini-Giampietro, D.E.1    Cherici, G.2    Alesiani, M.3    Carla, V.4    Moroni, F.5
  • 93
    • 0028224364 scopus 로고
    • Amflutizole, a xanthine oxidase inhibitor, inhibits free radical generation in the ischemic/reperfused rat cerebral cortex
    • Phillis, J. W., Sen, S., and Cao, X. (1994). Amflutizole, a xanthine oxidase inhibitor, inhibits free radical generation in the ischemic/reperfused rat cerebral cortex. Neurosci. Lett. 169:188-190.
    • (1994) Neurosci. Lett. , vol.169 , pp. 188-190
    • Phillis, J.W.1    Sen, S.2    Cao, X.3
  • 94
    • 0026583465 scopus 로고
    • Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
    • Przedborski, S., Kostic, V., Jackson-Lewis, V., Naini, A. B., Simonetti, S., Fahn, S., Carlson, E., Epstein, C. J., and Cadet, J. L. (1992). Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. J. Neurosci. 12:1658-1667.
    • (1992) J. Neurosci. , vol.12 , pp. 1658-1667
    • Przedborski, S.1    Kostic, V.2    Jackson-Lewis, V.3    Naini, A.B.4    Simonetti, S.5    Fahn, S.6    Carlson, E.7    Epstein, C.J.8    Cadet, J.L.9
  • 95
    • 0029984860 scopus 로고    scopus 로고
    • Role of neuronal nitric oxide synthase in MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-induced dopaminergic neurotoxicity
    • Przedborski, S., Jackson-Lewis, R., Yokoyama, V., Shibata, T., Dawson, V. L., and Dawson, T. M. (1996). Role of neuronal nitric oxide synthase in MPTP (N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine)-induced dopaminergic neurotoxicity. Proc. Natl. Acad. Sci. USA 93:5037-5042.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 5037-5042
    • Przedborski, S.1    Jackson-Lewis, R.2    Yokoyama, V.3    Shibata, T.4    Dawson, V.L.5    Dawson, T.M.6
  • 96
    • 0028915976 scopus 로고
    • Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from anti apoptotic gene to a pro apoptotic gene: Studies in yeast and neuronal cells
    • Rabizadeh, S., Gralla, E. B., Borchelt, D. R., Gwinn, R., Valentine, J. S., Sisodia, S., Wong, P., Lee, M., Hahn, H., and Bredesen, D. E. (1995). Mutations associated with amyotrophic lateral sclerosis convert superoxide dismutase from anti apoptotic gene to a pro apoptotic gene: studies in yeast and neuronal cells. Proc. Natl. Acad. Sci. USA 92:3024-3028.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3024-3028
    • Rabizadeh, S.1    Gralla, E.B.2    Borchelt, D.R.3    Gwinn, R.4    Valentine, J.S.5    Sisodia, S.6    Wong, P.7    Lee, M.8    Hahn, H.9    Bredesen, D.E.10
  • 97
    • 0025730414 scopus 로고
    • Peroxynitrite oxidation of sulfhydryls. the cytotoxic potential of superoxide and nitric oxide
    • Radi, R., Beckman, J. S., Bush, K. M., and Freeman, B. A. (1991). Peroxynitrite oxidation of sulfhydryls. The cytotoxic potential of superoxide and nitric oxide. J. Biol. Chem. 266:4244-4250.
    • (1991) J. Biol. Chem. , vol.266 , pp. 4244-4250
    • Radi, R.1    Beckman, J.S.2    Bush, K.M.3    Freeman, B.A.4
  • 98
    • 0027315347 scopus 로고
    • Delayed production of nitric oxide contributes to NMDA-mediated neuronal damage
    • Reif, D. W. (1993). Delayed production of nitric oxide contributes to NMDA-mediated neuronal damage. Neuroreport 4:566-568.
    • (1993) Neuroreport , vol.4 , pp. 566-568
    • Reif, D.W.1
  • 99
    • 0029064518 scopus 로고
    • Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation
    • Reynolds, I. J., and Hastings, H. (1995). Glutamate induces the production of reactive oxygen species in cultured forebrain neurons following NMDA receptor activation. J. Neurosci. 15:3318-3327.
    • (1995) J. Neurosci. , vol.15 , pp. 3318-3327
    • Reynolds, I.J.1    Hastings, H.2
  • 101
    • 0028888945 scopus 로고
    • Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model for amyotrophic lateral sclerosis
    • Ripps, M. E., Huntley, G. W., Hof, P. R., Morrison, J. H., and Gordon, J. W. (1995). Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model for amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 92:689-693.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 689-693
    • Ripps, M.E.1    Huntley, G.W.2    Hof, P.R.3    Morrison, J.H.4    Gordon, J.W.5
  • 103
    • 6544278446 scopus 로고
    • Decrements of intracellular NAD and ATP following exposure of primary neuronal cultures to neurotoxic concentrations
    • Sasaki, M., Brahambhatt, H. P., Dawson, T. M., and Dawson, V. L. (1995). Decrements of intracellular NAD and ATP following exposure of primary neuronal cultures to neurotoxic concentrations. Soc. Neurosci. Abstr. 21:520.
    • (1995) Soc. Neurosci. Abstr. , vol.21 , pp. 520
    • Sasaki, M.1    Brahambhatt, H.P.2    Dawson, T.M.3    Dawson, V.L.4
  • 104
    • 0023919239 scopus 로고
    • Inactivation of mammalian brain glutamine synthetase by oxygen radicals
    • Schor, N. F. (1988). Inactivation of mammalian brain glutamine synthetase by oxygen radicals. Brain Res. 456:17-21.
    • (1988) Brain Res. , vol.456 , pp. 17-21
    • Schor, N.F.1
  • 107
    • 0028685779 scopus 로고
    • Inducible nitric oxide synthase in the central nervous system
    • Sparrow, J. R. (1995). Inducible nitric oxide synthase in the central nervous system. J. Mol. Neurosci. 5:219-229.
    • (1995) J. Mol. Neurosci. , vol.5 , pp. 219-229
    • Sparrow, J.R.1
  • 108
    • 0026687022 scopus 로고
    • The biochemical mechanisms of the excitotoxicity of kainic acid
    • Sun, A. Y., Cheng, Y., Bu, Q., and Oldfield, F. (1992). The biochemical mechanisms of the excitotoxicity of kainic acid. Mol. Chem. Neuropathol. 17:51-63.
    • (1992) Mol. Chem. Neuropathol. , vol.17 , pp. 51-63
    • Sun, A.Y.1    Cheng, Y.2    Bu, Q.3    Oldfield, F.4
  • 109
    • 0026758642 scopus 로고
    • Mechanisms of cholecystokinin-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor mediated glutamate toxicity
    • Tamura, Y., Sato, Y., Akaike, A., and Shiomi, H. (1992). Mechanisms of cholecystokinin-induced protection of cultured cortical neurons against N-methyl-D-aspartate receptor mediated glutamate toxicity. Brain Res. 592:317-325.
    • (1992) Brain Res. , vol.592 , pp. 317-325
    • Tamura, Y.1    Sato, Y.2    Akaike, A.3    Shiomi, H.4
  • 110
    • 0023726166 scopus 로고
    • The repairability of oxidative free radical mediated damage to DNA
    • Teebor, G. W., Boorstein, R. J., and Cadet J. (1988). The repairability of oxidative free radical mediated damage to DNA. Int. J. Radiat. Biol. 54:131-150.
    • (1988) Int. J. Radiat. Biol. , vol.54 , pp. 131-150
    • Teebor, G.W.1    Boorstein, R.J.2    Cadet, J.3
  • 113
    • 0025286039 scopus 로고
    • Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum
    • Uemura, Y., Kowall, N. W., and Beal, M. F. (1990). Selective sparing of NADPH-diaphorase-somatostatin-neuropeptide Y neurons in ischemic gerbil striatum. Ann. Neurol. 27:620-625.
    • (1990) Ann. Neurol. , vol.27 , pp. 620-625
    • Uemura, Y.1    Kowall, N.W.2    Beal, M.F.3
  • 114
    • 0028618703 scopus 로고
    • Reactive oxygen species inhibit high-affinity glutamate uptake: Molecular mechanism and neuropathological implications
    • Volterra, A., Trotti, D., Floridi, S., and Racagni, G. (1994). Reactive oxygen species inhibit high-affinity glutamate uptake: Molecular mechanism and neuropathological implications. Ann. N.Y. Acad. Sci. 738:153-162.
    • (1994) Ann. N.Y. Acad. Sci. , vol.738 , pp. 153-162
    • Volterra, A.1    Trotti, D.2    Floridi, S.3    Racagni, G.4
  • 115
    • 0028348399 scopus 로고
    • NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase
    • Wallace, M. N., and Bisland, S. K. (1994). NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase. Neuroscience 59:905-919.
    • (1994) Neuroscience , vol.59 , pp. 905-919
    • Wallace, M.N.1    Bisland, S.K.2
  • 116
    • 0026471158 scopus 로고
    • Activated astrocytes of the mouse hippocampus containing high levels of NADPH-diaphorase
    • Wallace, M. N., and Fredens, K. (1992). Activated astrocytes of the mouse hippocampus containing high levels of NADPH-diaphorase. Neurochemistry 3:953-956.
    • (1992) Neurochemistry , vol.3 , pp. 953-956
    • Wallace, M.N.1    Fredens, K.2
  • 118
    • 0029053881 scopus 로고
    • An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneratio of mitochondria
    • Wong, P. C., Pardo, C. C., Borchelt, D. R., Lee, M. K., Copeland, N. G., Jenkins, N. A., Sisodia, S. S., Cleveland, D. W., and Price, D. L. (1995). An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneratio of mitochondria. Neuron 14:1105-1116.
    • (1995) Neuron , vol.14 , pp. 1105-1116
    • Wong, P.C.1    Pardo, C.C.2    Borchelt, D.R.3    Lee, M.K.4    Copeland, N.G.5    Jenkins, N.A.6    Sisodia, S.S.7    Cleveland, D.W.8    Price, D.L.9
  • 119
    • 0021071874 scopus 로고
    • A possible role of lipid peroxidation in cellular damages caused by cerebral ischemia and the protective effect of a-tocopherol administration
    • Yamamoto, M., Takeshi, S., Uozumi, T., Sogabe, T., Yamada, K., and Kawasaky, T. (1983). A possible role of lipid peroxidation in cellular damages caused by cerebral ischemia and the protective effect of a-tocopherol administration. Stroke 14:977-982.
    • (1983) Stroke , vol.14 , pp. 977-982
    • Yamamoto, M.1    Takeshi, S.2    Uozumi, T.3    Sogabe, T.4    Yamada, K.5    Kawasaky, T.6
  • 120
    • 0025622915 scopus 로고
    • The role of monoamino oxidase, iron-melanin interaction and intracellular calcium in Parkinson's disease
    • Youdim, M. B. H., Ben-Shachar, D., and Riederer, P. (1990). The role of monoamino oxidase, iron-melanin interaction and intracellular calcium in Parkinson's disease. J. Neural Transm. 32 (Suppl.):239-248.
    • (1990) J. Neural Transm. , vol.32 , Issue.SUPPL. , pp. 239-248
    • Youdim, M.B.H.1    Ben-Shachar, D.2    Riederer, P.3
  • 121
    • 0010471495 scopus 로고
    • Cellular defenses against damage from reactive oxygen species
    • Yu, B. P. (1994). Cellular defenses against damage from reactive oxygen species. Physiol. Rev. 74:139-162.
    • (1994) Physiol. Rev. , vol.74 , pp. 139-162
    • Yu, B.P.1
  • 122
    • 0027252586 scopus 로고
    • Nitroprusside improves blood flow and reduces brain damage after focal ischemia
    • Zhang, F., and Iadecola, C. (1993). Nitroprusside improves blood flow and reduces brain damage after focal ischemia. NeuroReport 4:559-562.
    • (1993) NeuroReport , vol.4 , pp. 559-562
    • Zhang, F.1    Iadecola, C.2
  • 123
    • 0026686667 scopus 로고
    • Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase
    • Zhang, J., and Snyder, S. H. (1992). Nitric oxide stimulates auto-ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase. Proc. Natl. Acad. Sci. USA 89: 9382-9385.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 9382-9385
    • Zhang, J.1    Snyder, S.H.2
  • 124
    • 0028088304 scopus 로고
    • Prolonged production of hydroxyl radical in rat hippocampus after brain ischemia-reperfusion is decreased by 21-aminosteroids
    • Zhang, J., and Piantadosi, C. A. (1994). Prolonged production of hydroxyl radical in rat hippocampus after brain ischemia-reperfusion is decreased by 21-aminosteroids. Neurosci. Lett. 177:127-130.
    • (1994) Neurosci. Lett. , vol.177 , pp. 127-130
    • Zhang, J.1    Piantadosi, C.A.2
  • 125
    • 0028294246 scopus 로고
    • Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity
    • Zhang, J., Dawson, V. L., Dawson, T. M., and Snyder, S. H. (1994). Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity. Science 263:687-689.
    • (1994) Science , vol.263 , pp. 687-689
    • Zhang, J.1    Dawson, V.L.2    Dawson, T.M.3    Snyder, S.H.4
  • 126
    • 0028050270 scopus 로고
    • Up-regulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal cerebral ischemia in rat
    • Zhang, Z. G., Chopp, M., Gautam, S., Zaloga, C., Zhang, R. L., Schmidt, H. H., Pollock, J. S., and Fostermann U. (1994). Up-regulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after focal cerebral ischemia in rat. Brain Res. 654:85-95.
    • (1994) Brain Res. , vol.654 , pp. 85-95
    • Zhang, Z.G.1    Chopp, M.2    Gautam, S.3    Zaloga, C.4    Zhang, R.L.5    Schmidt, H.H.6    Pollock, J.S.7    Fostermann, U.8


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