Phycocyanin extract reduces leukotriene B4 levels in arachidonic acid-induced mouse-ear inflammation test [1]

Journal of Pharmacy and Pharmacology

Volumn 51, Issue 5, 1999, Pages 641-642

  Romay, Cheyla ^a   Ledón, Nuris ^a   González, Ricardo ^a  

^a NATL CENTER FOR SCIENTIFIC RESEARCH   (Cuba)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CATECHOL; LEUKOTRIENE B4; LINOLEIC ACID; PHYCOCYANIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARACHIDONIC ACID METABOLISM; CONTROLLED STUDY; DOSE RESPONSE; EDEMA; LETTER; MOUSE; NONHUMAN; ORAL DRUG ADMINISTRATION; OTITIS;

EID: 0033064454     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357991772646     Document Type: Letter

References (7)

1. Benitez, F., Travieso, L., Dupeiron, R. (1997) Method for phycocyanin obtainment from microalgae. Cuban Patent (pending) RPI: 11
2. Crummey, A., Harper, G. P., Boyle, E. A., Mangan, F. R. (1987) Inhibition of arachidonic acid-induced ear oedema as a model for assessing topical anti-inflammatory compounds. Agents Actions 20: 69-76
3. González, R., Rodríguez, S., Romay, C., Ancheta, O., González, A., Armesto, J., Remirez, D., Merino, N. (1999) Anti-inflammatory activity of phycocyanin extract in acetic-acid induced colitis in rats. Pharmacol. Res. 39: 55-59
4. Opas, E. E, Bonney, R. J, Humes, J. L. (1985) Prostaglandin and leukotriene synthesis in mouse ears inflamed by arachidonic acid. J. Invest. Dermatol. 84: 253-256
5. Romay, C., Armesto, J., Remirez, D., González, R., Ledon, N., García, I. (1998a) Antioxidant and anti-inflammatory properties of c-phycocyanin from blue-green algae. Inflamm. Res. 47: 36-41
6. Romay, C., Ledón, N., González, R. (1998b) Further studies on anti-inflammatory activity of phycocyanin in some animal models of inflammation. Inflamm. Res. 47: 334-338
7. 4 in murine dermatitis models. Biochem. Pharmacol. 55: 297-304