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Volumn 18, Issue 4-5, 2000, Pages 433-437

Activation of oncogenic pathways in degenerating neurons in Alzheimer disease

Author keywords

[No Author keywords available]

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; CELL CYCLE; CELL DIVISION; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; NERVE DEGENERATION; NERVOUS SYSTEM DEVELOPMENT; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0034237405     PISSN: 07365748     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0736-5748(00)00010-1     Document Type: Article
Times cited : (85)

References (45)
  • 1
    • 0027131813 scopus 로고
    • Immunoreactivity of the nuclear antigen p105 is associated with plaques and tangles in Alzheimer's disease
    • Masliah E., Mallory M., Alford M., Hansen L.A., Saitoh T. Immunoreactivity of the nuclear antigen p105 is associated with plaques and tangles in Alzheimer's disease. Lab. Invest. 69:1993;562-569.
    • (1993) Lab. Invest. , vol.69 , pp. 562-569
    • Masliah, E.1    Mallory, M.2    Alford, M.3    Hansen, L.A.4    Saitoh, T.5
  • 2
    • 0029070087 scopus 로고
    • Ki-67 immunoreactivity in Alzheimer's disease and other neurodegenerative disorders
    • Smith T.W., Lippa C.F. Ki-67 immunoreactivity in Alzheimer's disease and other neurodegenerative disorders. J. Neuropathol. Exp. Neurol. 54:1995;297-303.
    • (1995) J. Neuropathol. Exp. Neurol. , vol.54 , pp. 297-303
    • Smith, T.W.1    Lippa, C.F.2
  • 3
    • 0030062245 scopus 로고    scopus 로고
    • Mitotic mechanisms in Alzheimer's disease?
    • Vincent I., Rosado M., Davies P. Mitotic mechanisms in Alzheimer's disease? J. Cell Biol. 132:1996;413-425.
    • (1996) J. Cell Biol. , vol.132 , pp. 413-425
    • Vincent, I.1    Rosado, M.2    Davies, P.3
  • 4
    • 0030761059 scopus 로고    scopus 로고
    • Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation
    • Li J., Xu M., Zhou H., Ma J., Potter H. Alzheimer presenilins in the nuclear membrane, interphase kinetochores, and centrosomes suggest a role in chromosome segregation. Cell. 90:1997;917-927.
    • (1997) Cell , vol.90 , pp. 917-927
    • Li, J.1    Xu, M.2    Zhou, H.3    Ma, J.4    Potter, H.5
  • 5
    • 0030921323 scopus 로고    scopus 로고
    • Abnormal expression of the cell cycle regulators p16 and cdk4 in Alzheimer's disease
    • McShea A., Harris P.L.R., Webster K.R., Wahl A.F., Smith M.A. Abnormal expression of the cell cycle regulators p16 and cdk4 in Alzheimer's disease. Am. J. Pathol. 150:1997;1933-1939.
    • (1997) Am. J. Pathol. , vol.150 , pp. 1933-1939
    • McShea, A.1    Harris, P.L.R.2    Webster, K.R.3    Wahl, A.F.4    Smith, M.A.5
  • 6
    • 0031043049 scopus 로고    scopus 로고
    • Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions
    • Nagy Z., Esiri M.M., Smith A.D. Expression of cell division markers in the hippocampus in Alzheimer's disease and other neurodegenerative conditions. Acta Neuropathol. 93:1997;294-300.
    • (1997) Acta Neuropathol. , vol.93 , pp. 294-300
    • Nagy, Z.1    Esiri, M.M.2    Smith, A.D.3
  • 7
    • 0030742818 scopus 로고    scopus 로고
    • Cell cycle markers in the hippocampus in Alzheimer's disease
    • Nagy Z., Esiri M.M., Cato A.M., Smith A.D. Cell cycle markers in the hippocampus in Alzheimer's disease. Acta Neuropathol. 94:1997;6-15.
    • (1997) Acta Neuropathol. , vol.94 , pp. 6-15
    • Nagy, Z.1    Esiri, M.M.2    Cato, A.M.3    Smith, A.D.4
  • 8
    • 0026694067 scopus 로고
    • Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease
    • Ledesma M.D., Correas I., Avila J., Diaz-Nido J. Implication of brain cdc2 and MAP2 kinases in the phosphorylation of tau protein in Alzheimer's disease. FEBS Lett. 308:1992;218-224.
    • (1992) FEBS Lett. , vol.308 , pp. 218-224
    • Ledesma, M.D.1    Correas, I.2    Avila, J.3    Diaz-Nido, J.4
  • 9
    • 0033537306 scopus 로고    scopus 로고
    • Signal transduction abnormalities in Alzheimer's disease: Evidence of a pathogenic stimuli
    • McShea A., Zelasko D.A., Gerst J.L., Smith M.A. Signal transduction abnormalities in Alzheimer's disease: evidence of a pathogenic stimuli. Brain Res. 815:1999;237-242.
    • (1999) Brain Res. , vol.815 , pp. 237-242
    • McShea, A.1    Zelasko, D.A.2    Gerst, J.L.3    Smith, M.A.4
  • 10
    • 0030800034 scopus 로고    scopus 로고
    • Two waves of cyclin B and proliferating cell nuclear antigen expression during dopamine-triggered neuronal apoptosis
    • Shirvan A., Ziv I., Machlin T., Zilkha-Falb R., Melamed E., Barzilai A. Two waves of cyclin B and proliferating cell nuclear antigen expression during dopamine-triggered neuronal apoptosis. J. Neurochem. 69:1997;539-549.
    • (1997) J. Neurochem. , vol.69 , pp. 539-549
    • Shirvan, A.1    Ziv, I.2    MacHlin, T.3    Zilkha-Falb, R.4    Melamed, E.5    Barzilai, A.6
  • 11
    • 0030798405 scopus 로고    scopus 로고
    • The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes
    • Chuang T.H., Hahn K.M., Lee J.D., Danley D.E., Bokoch G.M. The small GTPase Cdc42 initiates an apoptotic signaling pathway in Jurkat T lymphocytes. Mol. Biol. Cell. 8:1997;1687-1698.
    • (1997) Mol. Biol. Cell , vol.8 , pp. 1687-1698
    • Chuang, T.H.1    Hahn, K.M.2    Lee, J.D.3    Danley, D.E.4    Bokoch, G.M.5
  • 12
    • 0032559362 scopus 로고    scopus 로고
    • Rho GTPases and the actin cytoskeleton
    • Hall A. Rho GTPases and the actin cytoskeleton. Science. 279:1998;509-514.
    • (1998) Science , vol.279 , pp. 509-514
    • Hall, A.1
  • 13
    • 0029101360 scopus 로고
    • An essential role for Rho, Rac and Cdc42 GTPases in cell cycle progression through G1
    • Olson M.F., Ashworth A., Hall A. An essential role for Rho, Rac and Cdc42 GTPases in cell cycle progression through G1. Science. 269:1995;1270-1272.
    • (1995) Science , vol.269 , pp. 1270-1272
    • Olson, M.F.1    Ashworth, A.2    Hall, A.3
  • 14
    • 0028800305 scopus 로고
    • Activation of Rac1, RhoA, and mitogen-activated protein kinase is required for Ras transformation
    • Khosravi-Far R., Solski P.A., Clark G.J., Kinch M.S., Der C.J. Activation of Rac1, RhoA, and mitogen-activated protein kinase is required for Ras transformation. Mol. Cell Biol. 15:1995;6443-6453.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 6443-6453
    • Khosravi-Far, R.1    Solski, P.A.2    Clark, G.J.3    Kinch, M.S.4    Der, C.J.5
  • 15
    • 0028903247 scopus 로고
    • An essential role for Rac in Ras transformation
    • Qiu R.G., Chen J., Kirn D., McCormick F., Symons M. An essential role for Rac in Ras transformation. Nature. 374:1995;457-459.
    • (1995) Nature , vol.374 , pp. 457-459
    • Qiu, R.G.1    Chen, J.2    Kirn, D.3    McCormick, F.4    Symons, M.5
  • 16
    • 0030992814 scopus 로고    scopus 로고
    • Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation
    • Qiu R.G., Abo A., Mccormick F., Symons M. Cdc42 regulates anchorage-independent growth and is necessary for Ras transformation. Mol. Cell Biol. 17:1997;3449-3458.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 3449-3458
    • Qiu, R.G.1    Abo, A.2    McCormick, F.3    Symons, M.4
  • 17
    • 0028926263 scopus 로고
    • Parallel signal processing among mammalian MAPKs
    • Cano E., Mahadevan L.C. Parallel signal processing among mammalian MAPKs. Trends Biochem. Sci. 20:1995;117-122.
    • (1995) Trends Biochem. Sci. , vol.20 , pp. 117-122
    • Cano, E.1    Mahadevan, L.C.2
  • 18
    • 0029055812 scopus 로고
    • The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of JNK/SAPK signaling pathway
    • Coso O.A., Chiariello M., Yu J.C., Teramoto H., Crespo P., Xu N., Miki T., Gutkind J.S. The small GTP-binding proteins Rac1 and Cdc42 regulate the activity of JNK/SAPK signaling pathway. Cell. 81:1995;1137-1146.
    • (1995) Cell , vol.81 , pp. 1137-1146
    • Coso, O.A.1    Chiariello, M.2    Yu, J.C.3    Teramoto, H.4    Crespo, P.5    Xu, N.6    Miki, T.7    Gutkind, J.S.8
  • 19
    • 0030458602 scopus 로고    scopus 로고
    • A role for Jun-N-terminal kinase in anoikis: Suppression by bcl-2 and crmA
    • Frisch S.M., Vuori K., Kelaita D., Sicks S. A role for Jun-N-terminal kinase in anoikis: suppression by bcl-2 and crmA. J. Cell Biol. 135:1996;1377-1382.
    • (1996) J. Cell Biol. , vol.135 , pp. 1377-1382
    • Frisch, S.M.1    Vuori, K.2    Kelaita, D.3    Sicks, S.4
  • 21
    • 0030134173 scopus 로고    scopus 로고
    • The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platenum, UV irradiation or heat
    • Zanke B.W., Boudreau K., Rubie E., Winnett E., Tibbles L.A., Zon L., Kyriakis J., Liu F.F., Woodgett J.R. The stress-activated protein kinase pathway mediates cell death following injury induced by cis-platenum, UV irradiation or heat. Curr. Biol. 6:1996;606-613.
    • (1996) Curr. Biol. , vol.6 , pp. 606-613
    • Zanke, B.W.1    Boudreau, K.2    Rubie, E.3    Winnett, E.4    Tibbles, L.A.5    Zon, L.6    Kyriakis, J.7    Liu, F.F.8    Woodgett, J.R.9
  • 23
    • 0032584083 scopus 로고    scopus 로고
    • The small GTP-binding protein Cdc42 is required for nerve growth factor withdrawal-induced neuronal death
    • Bazenet C.E., Mota M.A., Rubin L.L. The small GTP-binding protein Cdc42 is required for nerve growth factor withdrawal-induced neuronal death. Proc. Natl. Acad. Sci., USA. 95:1998;3984-3989.
    • (1998) Proc. Natl. Acad. Sci., USA , vol.95 , pp. 3984-3989
    • Bazenet, C.E.1    Mota, M.A.2    Rubin, L.L.3
  • 26
    • 0031880094 scopus 로고    scopus 로고
    • A suicide note from Alzheimer disease neurons? (News and Views)
    • Perry G., Nunomura A., Smith M.A. A suicide note from Alzheimer disease neurons? (News and Views). Nature Med. 4:1998;897-898.
    • (1998) Nature Med. , vol.4 , pp. 897-898
    • Perry, G.1    Nunomura, A.2    Smith, M.A.3
  • 28
    • 0022414054 scopus 로고
    • Diagnosis of Alzheimer's disease
    • Khachaturian Z.S. Diagnosis of Alzheimer's disease. Arch. Neurol. 42:1985;1097-1105.
    • (1985) Arch. Neurol. , vol.42 , pp. 1097-1105
    • Khachaturian, Z.S.1
  • 29
    • 0025908356 scopus 로고
    • The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease
    • Mirra S.S., Heyman A., McKeel D., Sumi S.M., Crain B.J., Brownlee L.M., Vogel F.S., Hughes J.P., van Belle G., Berg L. The consortium to establish a registry for Alzheimer's disease (CERAD). Part II. Standardization of the neuropathologic assessment of Alzheimer's disease. Neurology. 41:1991;479-486.
    • (1991) Neurology , vol.41 , pp. 479-486
    • Mirra, S.S.1    Heyman, A.2    McKeel, D.3    Sumi, S.M.4    Crain, B.J.5    Brownlee, L.M.6    Vogel, F.S.7    Hughes, J.P.8    Van Belle, G.9    Berg, L.10
  • 32
    • 0027755363 scopus 로고
    • Cloning and characterization of seven novel Dictyostelium discoideum rac-related genes belonging to the rho family of GTPases
    • Bush J., Franek K., Cardelli J. Cloning and characterization of seven novel Dictyostelium discoideum rac-related genes belonging to the rho family of GTPases. Gene. 136:1993;61-68.
    • (1993) Gene , vol.136 , pp. 61-68
    • Bush, J.1    Franek, K.2    Cardelli, J.3
  • 33
    • 0029846873 scopus 로고    scopus 로고
    • Aberrant stress-induced phosphorylation of perikaryal neurofilaments
    • Giasson B.I., Mushynski W.E. Aberrant stress-induced phosphorylation of perikaryal neurofilaments. J. Biol. Chem. 271:1996;30,404-30,409.
    • (1996) J. Biol. Chem. , vol.271 , pp. 30
    • Giasson, B.I.1    Mushynski, W.E.2
  • 35
    • 0345419152 scopus 로고
    • Paired helical filaments from Alzheimer disease patients contain cytoskeletal components
    • Perry G., Rizzuto N., Autilio-Gambetti L., Gambetti P. Paired helical filaments from Alzheimer disease patients contain cytoskeletal components. Proc. Natl. Acad. Sci., USA. 82:1985;3916-3920.
    • (1985) Proc. Natl. Acad. Sci., USA , vol.82 , pp. 3916-3920
    • Perry, G.1    Rizzuto, N.2    Autilio-Gambetti, L.3    Gambetti, P.4
  • 36
    • 0030198344 scopus 로고    scopus 로고
    • Protein kinase cascades activated by stress and inflammatory cytokines
    • Kyriakis J.M., Avruch J. Protein kinase cascades activated by stress and inflammatory cytokines. Bioessays. 18:1996;567-577.
    • (1996) Bioessays , vol.18 , pp. 567-577
    • Kyriakis, J.M.1    Avruch, J.2
  • 37
    • 0030963035 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
    • Goedert M., Hasegawa M., Jakes R., Lawler S., Cuenda A., Cohen P. Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases. FEBS Lett. 409:1997;57-62.
    • (1997) FEBS Lett. , vol.409 , pp. 57-62
    • Goedert, M.1    Hasegawa, M.2    Jakes, R.3    Lawler, S.4    Cuenda, A.5    Cohen, P.6
  • 39
    • 0021344498 scopus 로고
    • Alzheimer paired helical filaments: Bulk isolation, solubility, and protein composition
    • Iqbal K., Zaidi T., Thompson C.H., Merz P.A., Wisniewski H.M. Alzheimer paired helical filaments: bulk isolation, solubility, and protein composition. Acta Neuropathol. 62:1984;167-177.
    • (1984) Acta Neuropathol. , vol.62 , pp. 167-177
    • Iqbal, K.1    Zaidi, T.2    Thompson, C.H.3    Merz, P.A.4    Wisniewski, H.M.5
  • 40
    • 0030455117 scopus 로고    scopus 로고
    • Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells
    • Boivin D., Bilodeau D., Beliveau R. Regulation of cytoskeletal functions by Rho small GTP-binding proteins in normal and cancer cells. Canad. J. Physiol. Pharmacol. 74:1996;801-810.
    • (1996) Canad. J. Physiol. Pharmacol. , vol.74 , pp. 801-810
    • Boivin, D.1    Bilodeau, D.2    Beliveau, R.3
  • 42
    • 0029015774 scopus 로고
    • The Rho family GTPases RhoA, Rac1, and Cdc42Hs regulate transcriptional activation by SRF
    • Hill C.S., Wynne J., Treisman R. The Rho family GTPases RhoA, Rac1, and Cdc42Hs regulate transcriptional activation by SRF. Cell. 81:1995;1159-1170.
    • (1995) Cell , vol.81 , pp. 1159-1170
    • Hill, C.S.1    Wynne, J.2    Treisman, R.3
  • 43
    • 0031026132 scopus 로고    scopus 로고
    • Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways
    • Westwick J.K., Lambert Q.T., Clark G.J., Symons M., Van Aelst L., Pestell R.G., Der C.J. Rac regulation of transformation, gene expression, and actin organization by multiple, PAK-independent pathways. Mol. Cell Biol. 17:1997;1324-1335.
    • (1997) Mol. Cell Biol. , vol.17 , pp. 1324-1335
    • Westwick, J.K.1    Lambert, Q.T.2    Clark, G.J.3    Symons, M.4    Van Aelst, L.5    Pestell, R.G.6    Der, C.J.7
  • 44
    • 0032504990 scopus 로고    scopus 로고
    • Control of mitotic events by the Cdc42 GTPase, the Clb2 cyclin and a member of the PAK kinase family
    • Tjandra H., Compton J., Kellogg D. Control of mitotic events by the Cdc42 GTPase, the Clb2 cyclin and a member of the PAK kinase family. Curr. Biol. 8:1998;991-1000.
    • (1998) Curr. Biol. , vol.8 , pp. 991-1000
    • Tjandra, H.1    Compton, J.2    Kellogg, D.3
  • 45
    • 0033037948 scopus 로고    scopus 로고
    • Re-entry into the cell cycle: A mechanism for neurodegeneration in Alzheimer disease
    • McShea A., Wahl A. F. and Smith M. A., Re-entry into the cell cycle: A mechanism for neurodegeneration in Alzheimer disease. Med Hypotheses, 1999, 52, 525-527.
    • (1999) Med Hypotheses , vol.52 , pp. 525-527
    • McShea, A.1    Wahl, A.F.2    Smith, M.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.