Superoxide dismutase delays neuronal apoptosis: A role for reactive oxygen species in programmed neuronal death

Neuron

Volumn 14, Issue 2, 1995, Pages 303-315

  Greenlund, Laura J S ^a   Deckwerth, Thomas L ^a   Johnson Jr , Eugene M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; NERVE GROWTH FACTOR;

AGE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRUCTURE; CONTROLLED STUDY; NERVE CELL NECROSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SYMPATHETIC NERVE CELL;

ANIMAL; APOPTOSIS; BASE SEQUENCE; CATTLE; CELLS, CULTURED; DNA PRIMERS; DNA, COMPLEMENTARY; GENE EXPRESSION; GENETIC VECTORS; HUMAN; KINETICS; MOLECULAR SEQUENCE DATA; NERVE GROWTH FACTORS; NEURONS; PROTEIN-TYROSINE KINASE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SUPERIOR CERVICAL GANGLION; SUPEROXIDE DISMUTASE; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TIME FACTORS; TRANSFECTION;

EID: 0028893492     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/0896-6273(95)90287-2     Document Type: Article

References (56)

1. Oxidative stress induces NF kappa B DNA binding and inducible NOS m RNA in human epithelial cells
2. Hydrogen peroxide mediates amyloid β protein toxicity
3. The nerve growth factor: purification as a 30,000-molecular-weight protein
4. bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death
5. A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus
6. Oxidant stress induces the proto-oncogenes c-fos and c-myc in mouse epidermal cells
7. Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor
8. Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase
9. Rapid and preferential activation of the c-jun gene during the mammalian UV response
10. Characterization of apoptosis in cultured rat sympathetic neurons after nerve growth factor withdrawal
11. The death programme in cultured sympathetic neurones can be suppressed at the posttranslational level by nerve growth factor, cyclic AMP, and depolarization
12. Apoptosic cell death occurs in hippocampal neurons cultured in a high oxygen atmosphere
13. Altered gene expression in neurons during programmed cell death identification of c-jun as necessary for neuronal apoptosis
14. Apoptosis mediated neurotoxicity induced by chronic application of β-amyloid fragment 25–35
15. Chronic depolarization prevents programmed death of sympathetic neurons in vitro but does not support growth: requirement for Ca2+ influx but not trk activation
16. Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of cyclin D1 during programmed cell death
17. Prevention of vertebrate neuronal death by the crmA gene
18. Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene
19. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian protooncogene bcl-2
20. Caenorhabditis elegans gene ced-9 protects cells from programmed cell death
21. Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death
22. Bcl-2 functions in an antioxidant pathway to prevent apoptosis
23. Techniques in the tissue culture of rat sympathetic neurons
24. Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species
25. Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics
26. Cytokine-induced programmed death of cultured sympathetic neurons
27. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
28. Nucleotide sequence of a cDNA clone encoding mouse protamine 1
29. Induction of apoptosis by the mouse Nedd2 gene which encodes a protein similar to the product of the Caenorhabitis elegans cell death gene ced-3 and the mammalian IL-1b-converting enzyme
30. Adaptive survival of rat sympathetic neurons cultured without supporting cells or exogenous nerve growth factor
31. Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
32. Apoptosis is induced by β-amyloid in cultured central nervous system neurons
33. DNA damage consistent with apoptosis in transient focal ischaemic neocortex
34. Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing radiation
35. Inhibitors of protein synthesis and RNA synthesis prevent neuronal death caused by nerve growth factor deprivation
36. Cytosine arabinoside kills postmitotic neurons in a fashion resembling trophic factor deprivation: evidence that a deoxycytidine-dependent process may be required for nerve growth factor signal transduction
37. Biochemical characterization of programmed cell death in NGF-deprived sympathetic neurons
38. Superoxide dismutase: an enzymicfunction for erythrocuprein (hemocuprein)
39. Induction of apoptosis in fibroblasts by IL-1 beta-converting enzyme, a mammalian homolog of the C. elegans cell death gene ced-3
40. Intern ucleosomal DNA cleavage involved in ischemia-induced neuronal death
41. Cell death during development of the nervous system
42. Cu/Zn superoxide dismutase activity in familial and sporadic amyotrophic lateral sclerosis
43. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
44. Chronic inhibition of superoxide dismutase produces apoptotic death of spinal neurons
45. cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor
46. Induction of DNA replication and expression of proto-oncogenes c-myc and c-fos in quiescent Balb/3T3 cells by xanthine/xanthine oxidase
47. Biochemistry of nitric oxide and its redox-activated forms
48. Down-regulation of copper/zinc superoxide dismutase causes apoptotic death in PC12 neuronal cells
49. Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair
50. Ich-1, an ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death
51. Developmental neuron death in the rat superior cervical sympathetic ganglion: cell counts and ultrastructure
52. Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA binding activity
53. The Caenorhabditis elegans genes ced-3 and ced-4 act cell autonomously to cause programmed cell death
54. The Caenorhabditis elegans cell death gene ced-4 encodes a novel protein and is expressed during the period of extensive programmed cell death
55. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme