-
1
-
-
0000899457
-
Dihydrofolate reductase
-
Blakley, R. L. & Benkovic, S. J. K., eds J. Wiley, New York
-
Blakley, R. L. (1985) Dihydrofolate reductase, in Folates and pterins (Blakley, R. L. & Benkovic, S. J. K., eds) vol. 1, pp. 191-253. J. Wiley, New York.
-
(1985)
Folates and Pterins
, vol.1
, pp. 191-253
-
-
Blakley, R.L.1
-
2
-
-
0021915972
-
Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim
-
Matthews, D. A., Bolin, J. T., Burridge, J. M., Filman, D. J., Volz, K. W., Kaufman, B. T., Beddell, C. R., Champness, J. N., Stammers, D. K. & Kraut, J. (1985) Refined crystal structures of Escherichia coli and chicken liver dihydrofolate reductase containing bound trimethoprim, J. Biol. Chem. 260, 381-391.
-
(1985)
J. Biol. Chem.
, vol.260
, pp. 381-391
-
-
Matthews, D.A.1
Bolin, J.T.2
Burridge, J.M.3
Filman, D.J.4
Volz, K.W.5
Kaufman, B.T.6
Beddell, C.R.7
Champness, J.N.8
Stammers, D.K.9
Kraut, J.10
-
3
-
-
0002801602
-
The comparative biochemistry of dihydrofolate reductase
-
Sirotnak, F. M., Burchill, J. J., Ensminger, W. D. & Montgomery, J. A., eds Academic Press Inc., New York
-
Freisheim, J. H. & Matthews, D. A. (1984) The comparative biochemistry of dihydrofolate reductase, in Folate antagonists as therapeutic agents (Sirotnak, F. M., Burchill, J. J., Ensminger, W. D. & Montgomery, J. A., eds) vol. 1, pp. 69-131. Academic Press Inc., New York.
-
(1984)
Folate Antagonists as Therapeutic Agents
, vol.1
, pp. 69-131
-
-
Freisheim, J.H.1
Matthews, D.A.2
-
4
-
-
0025308955
-
NMR studies of interactions of ligands with dihydrofolate reductase
-
Feeney, J. (1990) NMR studies of interactions of ligands with dihydrofolate reductase, Biochem. Pharmacol. 40, 141-152.
-
(1990)
Biochem. Pharmacol.
, vol.40
, pp. 141-152
-
-
Feeney, J.1
-
5
-
-
0343029167
-
NMR and mutagenesis studies of dihydrofolate reductase
-
Curtius, H. C., Ghisla, S. & Blau, N., eds de Gruyter, Berlin
-
Roberts, G. C. K. (1990) NMR and mutagenesis studies of dihydrofolate reductase, in Chemistry and biology of pteridines 1989. Pteridines and folic acids derivatives (Curtius, H. C., Ghisla, S. & Blau, N., eds) pp. 681-693. de Gruyter, Berlin.
-
(1990)
Chemistry and Biology of Pteridines 1989. Pteridines and Folic Acids Derivatives
, pp. 681-693
-
-
Roberts, G.C.K.1
-
6
-
-
0020441466
-
Crystal structures of E. coli and L. casei dihydrofolate reductase refined to 1.7 Å resolution. I. General features and binding of methotrexate
-
Bolin, J. T., Filman, D. J., Matthews, D. A., Hamlin, R. C. & Kraut, J. (1982) Crystal structures of E. coli and L. casei dihydrofolate reductase refined to 1.7 Å resolution. I. General features and binding of methotrexate, J. Biol. Chem. 257, 13650-13662.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 13650-13662
-
-
Bolin, J.T.1
Filman, D.J.2
Matthews, D.A.3
Hamlin, R.C.4
Kraut, J.5
-
7
-
-
0020442184
-
Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 Å resolution: II. Environment of bound NADPH and implications for catalysis
-
Filman, D. J., Bolin, J. T., Matthews, D. A. & Kraut, J. (1982) Crystal structures of Escherichia coli and Lactobacillus casei dihydrofolate reductase refined at 1.7 Å resolution: II. Environment of bound NADPH and implications for catalysis, J. Biol. Chem. 257, 13663-13672.
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 13663-13672
-
-
Filman, D.J.1
Bolin, J.T.2
Matthews, D.A.3
Kraut, J.4
-
8
-
-
0000195671
-
Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy
-
Bodenhausen, G. & Ruben, D. J. (1980) Natural abundance nitrogen-15 NMR by enhanced heteronuclear spectroscopy, Chem. Phys. Lett. 69, 185-188.
-
(1980)
Chem. Phys. Lett.
, vol.69
, pp. 185-188
-
-
Bodenhausen, G.1
Ruben, D.J.2
-
9
-
-
0024362326
-
15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: Application to interleukin 1β
-
15N Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1β. Biochemistry 28, 6150-6156.
-
(1989)
Biochemistry
, vol.28
, pp. 6150-6156
-
-
Marion, D.1
Driscoll, P.C.2
Kay, L.E.3
Wingfield, P.T.4
Bax, A.5
Gronenborn, A.M.6
Clore, G.M.7
-
12
-
-
0021806345
-
Nucleotide sequence of the dihydrofolate reductase gene of methotrexate-resistant Lactobacillus casei
-
Andrews, J., Clore, G. M., Davies, R. W., Gronenborn, A. M., Gronenborn, B., Kalderon, D., Papadopoulos, P. C., Schafer, S., Sims, P. F. G. & Stancombe, R. (1985) Nucleotide sequence of the dihydrofolate reductase gene of methotrexate-resistant Lactobacillus casei, Gene (Amst.) 35, 217-222.
-
(1985)
Gene (Amst.)
, vol.35
, pp. 217-222
-
-
Andrews, J.1
Clore, G.M.2
Davies, R.W.3
Gronenborn, A.M.4
Gronenborn, B.5
Kalderon, D.6
Papadopoulos, P.C.7
Schafer, S.8
Sims, P.F.G.9
Stancombe, R.10
-
13
-
-
0017065445
-
Large scale purification and characterisation of dihydrofolate reductase from a methotrexate-resistant strain of Lactobacillus casei
-
Dann, J. G., Ostler, G., Bjur, R. A., King, R. W., Scudder, P., Turner, P. C., Roberts, G. C. K., Burgen, A. S. V. & Harding, N. G. L. (1976) Large scale purification and characterisation of dihydrofolate reductase from a methotrexate-resistant strain of Lactobacillus casei, Biochem. J. 157, 559-571.
-
(1976)
Biochem. J.
, vol.157
, pp. 559-571
-
-
Dann, J.G.1
Ostler, G.2
Bjur, R.A.3
King, R.W.4
Scudder, P.5
Turner, P.C.6
Roberts, G.C.K.7
Burgen, A.S.V.8
Harding, N.G.L.9
-
14
-
-
0025900992
-
Dihydrofolate reductase: Sequential resonance assignments using 2D and 3D NMR and secondary structure determination in solution
-
Carr, M. D., Birdsall, B., Frenkiel, T. A., Bauer, C. J., Jimenez-Barbero, J., McCormick, J. H., Feeney, J. & Roberts, G. C. K. (1991) Dihydrofolate reductase: sequential resonance assignments using 2D and 3D NMR and secondary structure determination in solution. Biochemistry 30, 6330-6341.
-
(1991)
Biochemistry
, vol.30
, pp. 6330-6341
-
-
Carr, M.D.1
Birdsall, B.2
Frenkiel, T.A.3
Bauer, C.J.4
Jimenez-Barbero, J.5
McCormick, J.H.6
Feeney, J.7
Roberts, G.C.K.8
-
16
-
-
13444269041
-
Computer-optimized decoupling scheme for wideband applications and low-level operation
-
Shaka, A. J., Barker, P. B. & Freeman, R. (1985) Computer-optimized decoupling scheme for wideband applications and low-level operation, J. Magn. Reson. 64, 547-552.
-
(1985)
J. Magn. Reson.
, vol.64
, pp. 547-552
-
-
Shaka, A.J.1
Barker, P.B.2
Freeman, R.3
-
17
-
-
2642628181
-
A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants
-
States, D. J., Haberkorn, R. A. & Ruben, D. J. (1982) A two-dimensional nuclear Overhauser experiment with pure absorption phase in four quadrants, J. Magn. Reson. 48, 286-292.
-
(1982)
J. Magn. Reson.
, vol.48
, pp. 286-292
-
-
States, D.J.1
Haberkorn, R.A.2
Ruben, D.J.3
-
18
-
-
0029338320
-
Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturation
-
Mori, S., Abeygunawardana, C., O'Neil Johnson, M. & Van Zijl, P. C. M. (1995) Improved sensitivity of HSQC spectra of exchanging protons at short interscan delays using a new fast HSQC (FHSQC) detection scheme that avoids water saturation, J. Magn. Reson. 108, 94-98.
-
(1995)
J. Magn. Reson.
, vol.108
, pp. 94-98
-
-
Mori, S.1
Abeygunawardana, C.2
O'Neil Johnson, M.3
Van Zijl, P.C.M.4
-
19
-
-
0000517056
-
Improved linear prediction for truncated signals of known phase
-
Zhu, G. & Bax, A. (1990) Improved linear prediction for truncated signals of known phase, J. Magn. Reson. 90, 405-410.
-
(1990)
J. Magn. Reson.
, vol.90
, pp. 405-410
-
-
Zhu, G.1
Bax, A.2
-
20
-
-
0027665020
-
1H NMR-based assignments for side-chain resonances of Lactobacillus casei dihydrofolate reductase: Evidence for similarities between the solution and crystal structures of the enzyme
-
1H NMR-based assignments for side-chain resonances of Lactobacillus casei dihydrofolate reductase: evidence for similarities between the solution and crystal structures of the enzyme, J. Biomol. NMR 3, 535-546.
-
(1993)
J. Biomol. NMR
, vol.3
, pp. 535-546
-
-
Soteriou, A.1
Carr, M.D.2
Frenkiel, T.A.3
McCormick, J.H.4
Bauer, C.J.5
Sali, D.6
Birdsall, B.7
Feeney, J.8
-
21
-
-
0028000310
-
Solution structure of bound trimethoprim in its complex with Lactobacillus casei dihydrofolate reductase
-
Martorell, G., Gradwell, M. J., Birdsall, B., Bauer, C. J., Frenkiel, T. A., Cheung, H. T. A., Polshakov, V. I., Kuyper, L. & Feeney, J. (1994) Solution structure of bound trimethoprim in its complex with Lactobacillus casei dihydrofolate reductase. Biochemistry 33, 12416-12426.
-
(1994)
Biochemistry
, vol.33
, pp. 12416-12426
-
-
Martorell, G.1
Gradwell, M.J.2
Birdsall, B.3
Bauer, C.J.4
Frenkiel, T.A.5
Cheung, H.T.A.6
Polshakov, V.I.7
Kuyper, L.8
Feeney, J.9
-
25
-
-
0029142571
-
Structural and dynamic characterization of the phosphotyrosine binding region of a Src homology 2 domain-phosphopeptide complex by NMR relaxation, proton exchange, and chemical shift approaches
-
Pascal, S. M., Yamazaki, T., Singer, A. U., Kay, L. H. & Forman-Kay, J. D. (1995) Structural and dynamic characterization of the phosphotyrosine binding region of a Src homology 2 domain-phosphopeptide complex by NMR relaxation, proton exchange, and chemical shift approaches, Biochemistry 34, 11 353-11 362.
-
(1995)
Biochemistry
, vol.34
, pp. 11353-11362
-
-
Pascal, S.M.1
Yamazaki, T.2
Singer, A.U.3
Kay, L.H.4
Forman-Kay, J.D.5
-
26
-
-
0000450219
-
Conformational study of the dipeptide arginylglutamic acid and of its complex with nucleic bases
-
Lancelot, G., Mayer, R. & Helene, C. (1979) Conformational study of the dipeptide arginylglutamic acid and of its complex with nucleic bases, J. Am. Chem. Soc. 101, 1569-1576.
-
(1979)
J. Am. Chem. Soc.
, vol.101
, pp. 1569-1576
-
-
Lancelot, G.1
Mayer, R.2
Helene, C.3
-
27
-
-
0026694034
-
Towards an understanding of the arginine-aspartate interaction
-
Mitchell, J. B. O., Thornton, J. M., Singh, J. & Price, S. L. (1992) Towards an understanding of the arginine-aspartate interaction, J. Mol. Biol. 226, 251-262.
-
(1992)
J. Mol. Biol.
, vol.226
, pp. 251-262
-
-
Mitchell, J.B.O.1
Thornton, J.M.2
Singh, J.3
Price, S.L.4
-
28
-
-
0020378492
-
Receptor-based design of dihydrofolate reductase inhibitors: Comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues
-
Kuyper, L. F., Roth, B., Baccanari, D. P., Ferone, R., Beddell, C, R., Champness, J. N., Stammers, D. K., Dann, J. G., Norrington, F. E. A., Baker, D. J. & Goodford, P. J. (1982) Receptor-based design of dihydrofolate reductase inhibitors: comparison of crystallographically determined enzyme binding with enzyme affinity in a series of carboxy-substituted trimethoprim analogues, J. Med. Chem. 25, 1120-1122.
-
(1982)
J. Med. Chem.
, vol.25
, pp. 1120-1122
-
-
Kuyper, L.F.1
Roth, B.2
Baccanari, D.P.3
Ferone, R.4
Beddell, C.R.5
Champness, J.N.6
Stammers, D.K.7
Dann, J.G.8
Norrington, F.E.A.9
Baker, D.J.10
Goodford, P.J.11
-
29
-
-
0021646670
-
1H study of the interactions and conformations of rationally designed brodimoprim analogues in complexes with Lactobacillus casei dihydrofolate reductase
-
1H study of the interactions and conformations of rationally designed brodimoprim analogues in complexes with Lactobacillus casei dihydrofolate reductase, J. Med. Chem. 23, 1672-1676.
-
(1984)
J. Med. Chem.
, vol.23
, pp. 1672-1676
-
-
Birdsall, B.1
Feeney, J.2
Pascual, C.3
Roberts, G.C.K.4
Kompis, I.5
Then, R.L.6
Muller, K.7
Kroehn, A.8
-
30
-
-
0029123503
-
Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase
-
Morgan, W. D., Birdsall, B., Polshakov, V. I., Sali, D., Kompis, I. & Feeney, J. (1995) Solution structure of a brodimoprim analogue in its complex with Lactobacillus casei dihydrofolate reductase, Biochemistry 34, 11 690-11 702.
-
(1995)
Biochemistry
, vol.34
, pp. 11690-11702
-
-
Morgan, W.D.1
Birdsall, B.2
Polshakov, V.I.3
Sali, D.4
Kompis, I.5
Feeney, J.6
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