Validation of a new restraint docking method for solution structure determinations of protein-ligand complexes

Journal of Biomolecular NMR

Volumn 14, Issue 2, 1999, Pages 115-122

  Polshakov, Vladimir I ^a,b   Morgan, William D ^a   Birdsall, Berry ^a   Feeney, James ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b Center for Drug Chemistry   (Russian Federation)

Author keywords

Dihydrofolate reductase; Ligand docking; Protein ligand complexes; Structure determination

Indexed keywords

DIHYDROFOLATE REDUCTASE; METHOTREXATE; TRIMETREXATE;

ARTICLE; COMPLEX FORMATION; LACTOBACILLUS CASEI; LIGAND BINDING; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ANALYSIS; VALIDATION PROCESS;

BINDING SITES; LACTOBACILLUS CASEI; LIGANDS; METHOTREXATE; MODELS, MOLECULAR; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN CONFORMATION; REPRODUCIBILITY OF RESULTS; SOLUTIONS; TETRAHYDROFOLATE DEHYDROGENASE;

EID: 0033067461     PISSN: 09252738     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1008379225053     Document Type: Article

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