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Volumn 5, Issue 1, 1999, Pages 97-100

Caspase inhibition reduces apoptosis and increases survival of nigral transplants

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLTYROSINYLVALYLALANYLASPARTYLCHLOROMETHYLKETONE; CASPASE; ENZYME INHIBITOR; UNCLASSIFIED DRUG;

EID: 0033008216     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/4785     Document Type: Article
Times cited : (257)

References (24)
  • 1
    • 0030873946 scopus 로고    scopus 로고
    • Neural transplantation: A hope for patients with Parkinson's disease
    • Lindvall, O. Neural transplantation: a hope for patients with Parkinson's disease. Neuroreport 8, III-X (1997).
    • (1997) Neuroreport , vol.8
    • Lindvall, O.1
  • 2
    • 0030041034 scopus 로고    scopus 로고
    • Fetal nigral transplantation as a therapy for Parkinson's disease
    • Olanow, C.W., Kordower, J.H. & Freeman, T.B. Fetal nigral transplantation as a therapy for Parkinson's disease. Trends Neurosci. 19, 102-109 (1996).
    • (1996) Trends Neurosci. , vol.19 , pp. 102-109
    • Olanow, C.W.1    Kordower, J.H.2    Freeman, T.B.3
  • 3
    • 8944230650 scopus 로고    scopus 로고
    • Functional fetal nigral grafts in a patient with Parkinson's disease: Chemoanatomic, ultrastructural, and metabolic studies
    • Kordower, J.H. et al. Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies. J. Comp. Neurol. 24, 203-230 (1996).
    • (1996) J. Comp. Neurol. , vol.24 , pp. 203-230
    • Kordower, J.H.1
  • 4
    • 0031922226 scopus 로고    scopus 로고
    • Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease
    • Kordower J.H. et al. Fetal nigral grafts survive and mediate clinical benefit in a patient with Parkinson's disease. Mov. Disord. 13, 383-393 (1998).
    • (1998) Mov. Disord. , vol.13 , pp. 383-393
    • Kordower, J.H.1
  • 5
    • 0030248550 scopus 로고    scopus 로고
    • The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum
    • Barker, R.A., Dunnett, S.B., Faissner, A. & Fawcett, J.W. The time course of loss of dopaminergic neurons and the gliotic reaction surrounding grafts of embryonic mesencephalon to the striatum. Exp. Neurol. 141, 79-93 (1996).
    • (1996) Exp. Neurol. , vol.141 , pp. 79-93
    • Barker, R.A.1    Dunnett, S.B.2    Faissner, A.3    Fawcett, J.W.4
  • 6
    • 0032498835 scopus 로고    scopus 로고
    • Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats
    • Zawada, W.M. et al. Growth factors improve immediate survival of embryonic dopamine neurons after transplantation into rats. Brain Res. 786, 96-103 (1998).
    • (1998) Brain Res. , vol.786 , pp. 96-103
    • Zawada, W.M.1
  • 8
    • 0029092507 scopus 로고
    • Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro
    • Milligan, C.E. et al. Peptide inhibitors of the ICE protease family arrest programmed cell death of motoneurons in vivo and in vitro. Neuron 15, 385-393 (1995).
    • (1995) Neuron , vol.15 , pp. 385-393
    • Milligan, C.E.1
  • 9
    • 0031442999 scopus 로고    scopus 로고
    • Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide
    • Leist, M. et al. Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide. Mol. Med. 3, 750-764 (1997).
    • (1997) Mol. Med. , vol.3 , pp. 750-764
    • Leist, M.1
  • 10
    • 0030481801 scopus 로고    scopus 로고
    • Acute application of an interleukin-1 beta-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death
    • de Bilbao, F. & Dubois-Dauphin, M. Acute application of an interleukin-1 beta-converting enzyme-specific inhibitor delays axotomy-induced motoneurone death. Neuroreport 25, 3051-3054 (1996).
    • (1996) Neuroreport , vol.25 , pp. 3051-3054
    • De Bilbao, F.1    Dubois-Dauphin, M.2
  • 11
    • 0030614952 scopus 로고    scopus 로고
    • Inhibition of interleukin 1 beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage
    • Hara, H. et al. Inhibition of interleukin 1 beta converting enzyme family proteases reduces ischemic and excitotoxic neuronal damage. Proc. Natl. Acad. Sci. USA 94, 2007-2012 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2007-2012
    • Hara, H.1
  • 12
    • 0030804272 scopus 로고    scopus 로고
    • Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury
    • Yakovlev, A.G. et al. Activation of CPP32-like caspases contributes to neuronal apoptosis and neurological dysfunction after traumatic brain injury. J. Neurosci. 17, 7415-7424 (1997).
    • (1997) J. Neurosci. , vol.17 , pp. 7415-7424
    • Yakovlev, A.G.1
  • 13
    • 0030900980 scopus 로고    scopus 로고
    • Intracellular adenosine triphosphate (ATP) concentration: A switch in the decision between apoptosis and necrosis
    • Leist, M., Single, B., Castoldi, A.F., Kuhnle, S. & Nicotera, P. Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med. 185, 1481-1486 (1997).
    • (1997) J. Exp. Med. , vol.185 , pp. 1481-1486
    • Leist, M.1    Single, B.2    Castoldi, A.F.3    Kuhnle, S.4    Nicotera, P.5
  • 14
    • 0027944626 scopus 로고
    • Programmed cell death in developing grafts of fetal substantia nigra
    • Mahalik, T.J., Hahn, W.E., Clayton, G.H. & Owens, G.P. Programmed cell death in developing grafts of fetal substantia nigra. Exp. Neurol. 129, 27-36 (1994).
    • (1994) Exp. Neurol. , vol.129 , pp. 27-36
    • Mahalik, T.J.1    Hahn, W.E.2    Clayton, G.H.3    Owens, G.P.4
  • 15
  • 16
    • 0032404536 scopus 로고    scopus 로고
    • The central executioners of apoptosis: Caspases or mitochondria?
    • Green, D. & Kroemer, G. The central executioners of apoptosis: caspases or mitochondria? Trends Cell Biol. 8, 267-271 (1998).
    • (1998) Trends Cell Biol. , vol.8 , pp. 267-271
    • Green, D.1    Kroemer, G.2
  • 17
    • 0031816414 scopus 로고    scopus 로고
    • Apoptosis, excitotoxicity, and neuropathology
    • Leist, M. & Nicotera, P. Apoptosis, excitotoxicity, and neuropathology. Exp. Cell Res. 239, 183-201 (1998).
    • (1998) Exp. Cell Res. , vol.239 , pp. 183-201
    • Leist, M.1    Nicotera, P.2
  • 18
    • 0028899401 scopus 로고
    • Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease
    • Nakao, N. et al. Overexpressing Cu/Zn superoxide dismutase enhances survival of transplanted neurons in a rat model of Parkinson's disease. Nature Med. 1, 226-231 (1995).
    • (1995) Nature Med. , vol.1 , pp. 226-231
    • Nakao, N.1
  • 19
    • 0030298512 scopus 로고    scopus 로고
    • Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts
    • Rosenblad, C., Martinez-Serrano, A. & Björklund, A. Glial cell line-derived neurotrophic factor increases survival, growth and function of intrastriatal fetal nigral dopaminergic grafts. Neuroscience 75, 979-985 (1996).
    • (1996) Neuroscience , vol.75 , pp. 979-985
    • Rosenblad, C.1    Martinez-Serrano, A.2    Björklund, A.3
  • 20
    • 0027236053 scopus 로고
    • Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons-II. Effects on nigral transplants in vivo
    • Mayer, E., Fawcett, J.W. & Dunnett, S.B. Basic fibroblast growth factor promotes the survival of embryonic ventral mesencephalic dopaminergic neurons-II. Effects on nigral transplants in vivo. Neuroscience 56, 389-98 (1993).
    • (1993) Neuroscience , vol.56 , pp. 389-398
    • Mayer, E.1    Fawcett, J.W.2    Dunnett, S.B.3
  • 21
    • 0344938398 scopus 로고    scopus 로고
    • Treatment with the spintrap agent α-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons
    • Karlsson, J., Emgård, M., Rosenblad, C. & Brundin, P. Treatment with the spintrap agent α-phenyl-N-tert-butyl nitrone does not enhance the survival of embryonic or adult dopamine neurons. Brain Res. 805, 155-168 (1998).
    • (1998) Brain Res. , vol.805 , pp. 155-168
    • Karlsson, J.1    Emgård, M.2    Rosenblad, C.3    Brundin, P.4
  • 22
    • 0031868227 scopus 로고    scopus 로고
    • An improved method for detection of apoptosis in tissue sections and cell culture, using the TUNEL technique combined with Hoechst stain
    • Whiteside, G., Cougnon, N., Hunt, S.P. & Munglani, R. An improved method for detection of apoptosis in tissue sections and cell culture, using the TUNEL technique combined with Hoechst stain. Brain Res. Brain Res. Protoc. 2, 160-164 (1998).
    • (1998) Brain Res. Brain Res. Protoc. , vol.2 , pp. 160-164
    • Whiteside, G.1    Cougnon, N.2    Hunt, S.P.3    Munglani, R.4
  • 23
    • 0031927150 scopus 로고    scopus 로고
    • Quinolinic acid-induced inflammation in the striatum does not impair the survival of neural allografts in the rat
    • Duan, W.-M., Widner, H., Cameron, R.M. & Brundin, P. Quinolinic acid-induced inflammation in the striatum does not impair the survival of neural allografts in the rat. Eur. J. Neurosci. 10, 2595-2606 (1998).
    • (1998) Eur. J. Neurosci. , vol.10 , pp. 2595-2606
    • Duan, W.-M.1    Widner, H.2    Cameron, R.M.3    Brundin, P.4
  • 24
    • 0026339976 scopus 로고
    • Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator
    • West, M.J., Slomianka, L. & Gundersen, H.J. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat. Rec. 231, 482-497 (1991).
    • (1991) Anat. Rec. , vol.231 , pp. 482-497
    • West, M.J.1    Slomianka, L.2    Gundersen, H.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.