-
2
-
-
0003525629
-
Clinical guidelines on the identification evaluation and treatment of overweight and obesity in adults - The evidence report
-
National Heart Lung and Blood Institute. Clinical guidelines on the identification evaluation and treatment of overweight and obesity in adults - the evidence report. Obes. Res. 6(Suppl. 2), 515-2905 (1998).
-
(1998)
Obes. Res.
, vol.6
, Issue.2 SUPPL.
, pp. 515-2905
-
-
-
3
-
-
0032695482
-
Annual deaths attributable to obesity in the United States
-
Allison D. B. et al. Annual deaths attributable to obesity in the United States. J. Am. Med. Assoc. 282, 1530-1538 (1999).
-
(1999)
J. Am. Med. Assoc.
, vol.282
, pp. 1530-1538
-
-
Allison, D.B.1
-
4
-
-
0031613806
-
Drug treatment of obesity. Don't throw out the baby with the bath water
-
Bray, G. A. Drug treatment of obesity. Don't throw out the baby with the bath water. Am. J. Clin. Nutr. 67, 1-2 (1998).
-
(1998)
Am. J. Clin. Nutr.
, vol.67
, pp. 1-2
-
-
Bray, G.A.1
-
6
-
-
0033305646
-
A review of current and potential drugs for treatment of obesity
-
Bray, G. A. & Greenway, F. L. A review of current and potential drugs for treatment of obesity. Endocr. Rev. 20, 803-875 (1999).
-
(1999)
Endocr. Rev.
, vol.20
, pp. 803-875
-
-
Bray, G.A.1
Greenway, F.L.2
-
7
-
-
0032956713
-
Regulation of body weight in humans
-
Jequier, E. & Tappy, L. Regulation of body weight in humans. Physiol. Rev. 79, 451-480 (1999).
-
(1999)
Physiol. Rev.
, vol.79
, pp. 451-480
-
-
Jequier, E.1
Tappy, L.2
-
8
-
-
0031602176
-
Sibutramine reduces food intake in nondieting women with obesity
-
Rolls, B. J., Shide, D. J., Thorwart, M. L. & Ulbrecht, J. S. Sibutramine reduces food intake in nondieting women with obesity. Obes. Res. 6, 1-11 (1998).
-
(1998)
Obes. Res.
, vol.6
, pp. 1-11
-
-
Rolls, B.J.1
Shide, D.J.2
Thorwart, M.L.3
Ulbrecht, J.S.4
-
9
-
-
0031740856
-
Thermogenic effects of sibutramine in humans
-
Hansen, D. L. et al. Thermogenic effects of sibutramine in humans. Am. J. Clin. Nutr. 68, 1180-1186 (1998).
-
(1998)
Am. J. Clin. Nutr.
, vol.68
, pp. 1180-1186
-
-
Hansen, D.L.1
-
10
-
-
0032012915
-
Effects of sibutramine on resting metabolic rate and weight loss in overweight women
-
Seagle, H. M., Gessesen, D. H. & Hill, J. O. Effects of sibutramine on resting metabolic rate and weight loss in overweight women. Obes. Res. 6, 115-121 (1998).
-
(1998)
Obes. Res.
, vol.6
, pp. 115-121
-
-
Seagle, H.M.1
Gessesen, D.H.2
Hill, J.O.3
-
11
-
-
0033090465
-
Sibutramine produces dose-related weight loss
-
Bray, G. A. et al. Sibutramine produces dose-related weight loss. Obes. Res. 7, 189-198 (1999).
-
(1999)
Obes. Res.
, vol.7
, pp. 189-198
-
-
Bray, G.A.1
-
12
-
-
0033082197
-
Long-term maintenance of weight loss after a very low calorie diet: Efficacy and tolerability of sibutramine
-
Apfelbaum, M. et al. Long-term maintenance of weight loss after a very low calorie diet: efficacy and tolerability of sibutramine. Am. J. Med 106, 179-184 (1999).
-
(1999)
Am. J. Med
, vol.106
, pp. 179-184
-
-
Apfelbaum, M.1
-
14
-
-
0026604775
-
Initial studies in humans with the novel gastrointestinal lipaseinhibitor Ro 18-0647 (tetrahydrolipstatin)
-
Hauptman, J. B., Jeunet, F. S. & Hartmann, D. Initial studies in humans with the novel gastrointestinal lipaseinhibitor Ro 18-0647 (tetrahydrolipstatin). Am. J. Clin. Nutr. 55, 309S-313S (1992).
-
(1992)
Am. J. Clin. Nutr.
, vol.55
-
-
Hauptman, J.B.1
Jeunet, F.S.2
Hartmann, D.3
-
15
-
-
0032543870
-
Randomized placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group
-
Sjostrom, L. et al. Randomized placebo-controlled trial of orlistat for weight loss and prevention of weight regain in obese patients. European Multicentre Orlistat Study Group. Lancet 352, 167-172 (1998).
-
(1998)
Lancet
, vol.352
, pp. 167-172
-
-
Sjostrom, L.1
-
16
-
-
0033585499
-
Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat. a randomized controlled trial
-
Davidson, M. H., Hauptman, J. & DiGirolamo, M. Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat. A randomized controlled trial. J. Am. Med. Assoc. 281, 235-242 (1999).
-
(1999)
J. Am. Med. Assoc.
, vol.281
, pp. 235-242
-
-
Davidson, M.H.1
Hauptman, J.2
DiGirolamo, M.3
-
17
-
-
0031904104
-
Role of orlistat in the treatment of obese patients with type 2 diabetes
-
Hollander, P. et al. Role of orlistat in the treatment of obese patients with type 2 diabetes. Diabetes Care 21, 1288-1294 (1998).
-
(1998)
Diabetes Care
, vol.21
, pp. 1288-1294
-
-
Hollander, P.1
-
18
-
-
0033020351
-
Orlistat, a lipase inhibitor, for weight maintenance after conventional dieting - A 1 year study
-
Hill, J. O. et al. Orlistat, a lipase inhibitor, for weight maintenance after conventional dieting - A 1 year study. Am. J. Clin. Nutr. 9, 1108-1116 (1999).
-
(1999)
Am. J. Clin. Nutr.
, vol.9
, pp. 1108-1116
-
-
Hill, J.O.1
-
19
-
-
0001450312
-
Long-term tolerability profile of orlistat, an intestinal lipase inhibitor
-
Conavatchel, W. Long-term tolerability profile of orlistat, an intestinal lipase inhibitor. Diabetologia 40, A196 (1997).
-
(1997)
Diabetologia
, vol.40
-
-
Conavatchel, W.1
-
20
-
-
0021844412
-
Enhanced thermogenic responsiveness during chronic ephedrine treatment in man
-
Astrup, A., Lundsgaard, C., Madsen, J., & Christensen, N. J. Enhanced thermogenic responsiveness during chronic ephedrine treatment in man. Am. J. Clin. Nutr. 42, 83-94 (1985).
-
(1985)
Am. J. Clin. Nutr.
, vol.42
, pp. 83-94
-
-
Astrup, A.1
Lundsgaard, C.2
Madsen, J.3
Christensen, N.J.4
-
21
-
-
0026523485
-
The effect and safety of an ephedrine/caffeine compound compared to ephedrine, caffeine and placebo in obese subjects on an energy-restricted diet. a double-blind trial
-
Astrup, A., Breum, L., Toubro, S., Hein, P. & Quaade, F. The effect and safety of an ephedrine/caffeine compound compared to ephedrine, caffeine and placebo in obese subjects on an energy-restricted diet. A double-blind trial. Int. J. Obes. Relat. Metab. Disord. 16, 269-277 (1992).
-
(1992)
Int. J. Obes. Relat. Metab. Disord.
, vol.16
, pp. 269-277
-
-
Astrup, A.1
Breum, L.2
Toubro, S.3
Hein, P.4
Quaade, F.5
-
22
-
-
0027742891
-
The acute and chronic effects of ephedrine/caffeine mixtures on energy expenditure and glucose metabolism in humans
-
Toubro, S., Astrup, L., Breum, L. & Quaade, F. The acute and chronic effects of ephedrine/caffeine mixtures on energy expenditure and glucose metabolism in humans. Int. J. Obes. Relat. Metab. Disord. 7, S73-S77 (1993).
-
(1993)
Int. J. Obes. Relat. Metab. Disord.
, vol.7
-
-
Toubro, S.1
Astrup, L.2
Breum, L.3
Quaade, F.4
-
23
-
-
0026648513
-
The effect of ephedrine/caffeine mixture on energy expenditure and body composition in obese women
-
Astrup, A. et al. The effect of ephedrine/caffeine mixture on energy expenditure and body composition in obese women. Metabolism 41, 686-688 (1992).
-
(1992)
Metabolism
, vol.41
, pp. 686-688
-
-
Astrup, A.1
-
24
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang, Y. et al. Positional cloning of the mouse obese gene and its human homologue. Nature 372, 425-432 (1994).
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
-
25
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartaglia, L. A. et al. Identification and expression cloning of a leptin receptor, OB-R. Cell 83, 1263-1271 (1995).
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartaglia, L.A.1
-
26
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
Chen, H. et al. Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84, 491-495 (1996).
-
(1996)
Cell
, vol.84
, pp. 491-495
-
-
Chen, H.1
-
27
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
Lee, G. H. et al. Abnormal splicing of the leptin receptor in diabetic mice. Nature 379, 632-635 (1996).
-
(1996)
Nature
, vol.379
, pp. 632-635
-
-
Lee, G.H.1
-
28
-
-
0030028959
-
Phenotypes of mouse diabetes and rat fat due to mutations in the OB (leptin) receptor
-
Chua, S. C. Jr et al. Phenotypes of mouse diabetes and rat fat due to mutations in the OB (leptin) receptor. Science 271, 994-996 (1996).
-
(1996)
Science
, vol.271
, pp. 994-996
-
-
Chua S.C., Jr.1
-
29
-
-
0030889192
-
Targeted disruption of the melanocortin-4 receptor results in obesity in mice
-
Huszar, D. et al. Targeted disruption of the melanocortin-4 receptor results in obesity in mice. Cell 88, 131-141 (1997).
-
(1997)
Cell
, vol.88
, pp. 131-141
-
-
Huszar, D.1
-
31
-
-
0028355355
-
Effect of intravenous human gastrin-releasing peptide on food intake in humans
-
Gutzwiller J. P. et al. Effect of intravenous human gastrin-releasing peptide on food intake in humans. Gastroenterology 106, 1168-1173 (1994).
-
(1994)
Gastroenterology
, vol.106
, pp. 1168-1173
-
-
Gutzwiller, J.P.1
-
32
-
-
0032005005
-
Glucagon-like peptide promotes satiety and suppresses energy intake in humans
-
Flint, A., Raben, A. I., Astrup, A. & Holst, J. J. Glucagon-like peptide [ promotes satiety and suppresses energy intake in humans. J. Clin. Invest. 101, 515-520 (1998).
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 515-520
-
-
Flint, A.1
Raben, A.I.2
Astrup, A.3
Holst, J.J.4
-
33
-
-
0033175006
-
Glucagon-like peptide-1 (GLP-1) - An intestinal hormone, signaling nutritional abundance, with an unusual therapeutic potential
-
Holst, J. J. Glucagon-like peptide-1 (GLP-1) - an intestinal hormone, signaling nutritional abundance, with an unusual therapeutic potential. Trends Endocrinol. Metab. 10, 229-235 (1999).
-
(1999)
Trends Endocrinol. Metab.
, vol.10
, pp. 229-235
-
-
Holst, J.J.1
-
34
-
-
0032966882
-
Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2
-
Gutzwiller, J. P. et al. Glucagon-like peptide-1 promotes satiety and reduces food intake in patients with diabetes mellitus type 2. Am. J. Physiol. 276 (5 Pt 2), R1541-R1544 (1999).
-
(1999)
Am. J. Physiol.
, vol.276
, Issue.5 PART 2
-
-
Gutzwiller, J.P.1
-
35
-
-
0031179155
-
Enterostatin - A peptide regulating fat intake
-
Erlanson-Albertsson, C. & York, D. Enterostatin - a peptide regulating fat intake. Obes. Res. 5, 360-372 (1997).
-
(1997)
Obes. Res.
, vol.5
, pp. 360-372
-
-
Erlanson-Albertsson, C.1
York, D.2
-
36
-
-
0006760742
-
The effect of oral enterostatin on hunger and food intake in human volunteers
-
Smeets, M., Geiselman, P., Bray, G. A. & York, D. A. The effect of oral enterostatin on hunger and food intake in human volunteers. FASEB J. 13, A871 (1999).
-
(1999)
FASEB J.
, vol.13
-
-
Smeets, M.1
Geiselman, P.2
Bray, G.A.3
York, D.A.4
-
37
-
-
0000660269
-
Intraventricular administration of enterostatin decreases food intake in baboons
-
Wetherford, S. C. et al. Intraventricular administration of enterostatin decreases food intake in baboons. Appetite 19, 225 (1992).
-
(1992)
Appetite
, vol.19
, pp. 225
-
-
Wetherford, S.C.1
-
38
-
-
0028060577
-
Modulation of food intake by peripherally administered amylin
-
Morley, J. E., Flood, J. F., Horowitz, M., Morley, P. M. & Walter, M. J. Modulation of food intake by peripherally administered amylin. Am. J. Physiol 276(1 Pt 2), R178-R184 (1994).
-
(1994)
Am. J. Physiol
, vol.276
, Issue.1 PART 2
-
-
Morley, J.E.1
Flood, J.F.2
Horowitz, M.3
Morley, P.M.4
Walter, M.J.5
-
39
-
-
0029911772
-
Effects of pyruvate and lactate on food intake in rat strains sensitive and resistant to dietary obesity
-
Nagase, H., Bray, G. A. & York, D. A. Effects of pyruvate and lactate on food intake in rat strains sensitive and resistant to dietary obesity. Physiol. Behav. 59, 555-560 (1996).
-
(1996)
Physiol. Behav.
, vol.59
, pp. 555-560
-
-
Nagase, H.1
Bray, G.A.2
York, D.A.3
-
40
-
-
0032821484
-
Control of food intake by fatty acid oxidation and ketogenesis
-
Scharrer, E. Control of food intake by fatty acid oxidation and ketogenesis. Nutrition 15, 704-714 (1999).
-
(1999)
Nutrition
, vol.15
, pp. 704-714
-
-
Scharrer, E.1
-
41
-
-
0015988722
-
Effect of (-)-hydroxycitrate upon the accumulation of lipid in the rat. II. Appetite
-
Sullivan, A.C., Triscari, J., Hamilton, J.G. & Miller, O. N. Effect of (-)-hydroxycitrate upon the accumulation of lipid in the rat. II. Appetite, Lipids 9, 129-134 (1974).
-
(1974)
Lipids
, vol.9
, pp. 129-134
-
-
Sullivan, A.C.1
Triscari, J.2
Hamilton, J.G.3
Miller, O.N.4
-
42
-
-
0032508876
-
Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: A randomized controlled trial
-
Heymsfield, S. B. et al. Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial. J. Am. Med. Assoc. 280, 1596-1600 (1998).
-
(1998)
J. Am. Med. Assoc.
, vol.280
, pp. 1596-1600
-
-
Heymsfield, S.B.1
-
43
-
-
0031919866
-
Neurochemical changes after imbalanced diets suggest a brain circuit mediating anorectic responses to amino acid deficiency in rats
-
Gietzen, D. W., Erecius, L. F. & Rogers, Q. R. Neurochemical changes after imbalanced diets suggest a brain circuit mediating anorectic responses to amino acid deficiency in rats. J. Nutr. 128, 771-781 (1998).
-
(1998)
J. Nutr.
, vol.128
, pp. 771-781
-
-
Gietzen, D.W.1
Erecius, L.F.2
Rogers, Q.R.3
-
44
-
-
0032799035
-
The role of apolipoprotein A-IV in food intake regulation
-
Tso, P., Liu, M., & Kalogeris, T. J. The role of apolipoprotein A-IV in food intake regulation. J. Nutr. 8, 1503-1506 (1999).
-
(1999)
J. Nutr.
, vol.8
, pp. 1503-1506
-
-
Tso, P.1
Liu, M.2
Kalogeris, T.J.3
-
45
-
-
0033586747
-
The role of leptin in human obesity and disease - A review of current evidence
-
Mantzoros, C. S. The role of leptin in human obesity and disease - a review of current evidence. Ann. Intern. Med. 130, 671-680 (1999).
-
(1999)
Ann. Intern. Med.
, vol.130
, pp. 671-680
-
-
Mantzoros, C.S.1
-
46
-
-
0032772960
-
The central melanocortin system and energy homeostasis
-
Cone, R. D. The central melanocortin system and energy homeostasis. Trends Endocrinol. Metab. 10, 211-216 (1999).
-
(1999)
Trends Endocrinol. Metab.
, vol.10
, pp. 211-216
-
-
Cone, R.D.1
-
47
-
-
0033017571
-
The role of agouti-related protein in regulating body-weight. mol
-
Wilson, B. D., Ollmann, M. M. & Barsh, G. S. The role of agouti-related protein in regulating body-weight. mol. Med. Today 5, 250-256 (1999).
-
(1999)
Med. Today
, vol.5
, pp. 250-256
-
-
Wilson, B.D.1
Ollmann, M.M.2
Barsh, G.S.3
-
48
-
-
0032492893
-
Hypothalamic CART is a now anorectic peptide regulated by leptin
-
Kristensen, P. et al. Hypothalamic CART is a now anorectic peptide regulated by leptin. Nature 393, 72-76 (1998).
-
(1998)
Nature
, vol.393
, pp. 72-76
-
-
Kristensen, P.1
-
49
-
-
0032747280
-
Recombinant leptin for weight loss in obese and lean adults: A randomized, controlled, dose-escalation study
-
Heymsfield, S. B. et al. Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation study. J. Am. Med. Assoc. 282, 1568-1575.
-
J. Am. Med. Assoc.
, vol.282
, pp. 1568-1575
-
-
Heymsfield, S.B.1
-
50
-
-
0033575993
-
Effects of recombinant leptin therapy in a child with congenital leptin deficiency
-
Farooqi, I. S. et al. Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N. Engl. J. Med. 341, 879-884 (1999).
-
(1999)
N. Engl. J. Med.
, vol.341
, pp. 879-884
-
-
Farooqi, I.S.1
-
51
-
-
0032848779
-
Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressingleptin
-
Ogawa, Y. et al. Increased glucose metabolism and insulin sensitivity in transgenic skinny mice overexpressingleptin. Diabetes 48, 1822-1829 (1999).
-
(1999)
Diabetes
, vol.48
, pp. 1822-1829
-
-
Ogawa, Y.1
-
52
-
-
0033324777
-
Activation of SOCS-3 messenger ribonucleic acid in the hypothalamus by ciliary neurotrophic factor
-
Bjorbaek, C. et al. Activation of SOCS-3 messenger ribonucleic acid in the hypothalamus by ciliary neurotrophic factor. Endocrinology 140, 2035-2043 (1999).
-
(1999)
Endocrinology
, vol.140
, pp. 2035-2043
-
-
Bjorbaek, C.1
-
53
-
-
0031657350
-
Central control of feeding behavior by neuropeptide Y
-
Zimanyi, I. A., Fathi, Z. & Poindexter, G. S. Central control of feeding behavior by neuropeptide Y. Curr. Pharm. Des. 4, 349-366 (1998).
-
(1998)
Curr. Pharm. Des.
, vol.4
, pp. 349-366
-
-
Zimanyi, I.A.1
Fathi, Z.2
Poindexter, G.S.3
-
54
-
-
0342308870
-
-
Louisiana State Univ. Press, Baton Rouge
-
Palmiter, R. D. et al. in Pennington Center Nutrition Series: Nutrition, Genetics, and Obesity 269-286 (Louisiana State Univ. Press, Baton Rouge, 1999).
-
(1999)
Pennington Center Nutrition Series: Nutrition, Genetics, and Obesity
, pp. 269-286
-
-
Palmiter, R.D.1
-
55
-
-
0032863468
-
Obesity in the mouse model of proopiomelanocortin deficiency responds to peripheral melanocortin
-
Yaswen, L., Diehl, N., Brennan, M. B. & Hochgeschwender, U. Obesity in the mouse model of proopiomelanocortin deficiency responds to peripheral melanocortin. Nature Med. 5, 1066-1070 (1999).
-
(1999)
Nature Med.
, vol.5
, pp. 1066-1070
-
-
Yaswen, L.1
Diehl, N.2
Brennan, M.B.3
Hochgeschwender, U.4
-
56
-
-
0033566128
-
Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1
-
Chambers, J. et al. Melanin-concentrating hormone is the cognate ligand for the orphan G-protein-coupled receptor SLC-1. Nature 400, 261-269 (1999).
-
(1999)
Nature
, vol.400
, pp. 261-269
-
-
Chambers, J.1
-
57
-
-
0033566084
-
Molecular characterization of the melanin-concentrating-hormone receptor
-
Saito, Y. et al. Molecular characterization of the melanin-concentrating-hormone receptor. Nature 400, 265-269 (1999).
-
(1999)
Nature
, vol.400
, pp. 265-269
-
-
Saito, Y.1
-
58
-
-
0032542294
-
Mice lacking melanin-concentrating hormone are hypophagic and lean
-
Shimada, M. et al. Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature 396, 670-673 (1998).
-
(1998)
Nature
, vol.396
, pp. 670-673
-
-
Shimada, M.1
-
59
-
-
0033194242
-
The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor
-
Lembo, P. M. et al. The receptor for the orexigenic peptide melanin-concentrating hormone is a G-protein-coupled receptor Nature Cell Biol. 5, 267-271 (1999).
-
(1999)
Nature Cell Biol.
, vol.5
, pp. 267-271
-
-
Lembo, P.M.1
-
60
-
-
0029917181
-
Opioid receptor subtype control of galinin-induced feeding
-
Barton, C., York, D. A. & Bray, G. A. Opioid receptor subtype control of galinin-induced feeding. Peptides 17, 237-240 (1996).
-
(1996)
Peptides
, vol.17
, pp. 237-240
-
-
Barton, C.1
York, D.A.2
Bray, G.A.3
-
61
-
-
0032446037
-
Transcriptional control of the galanin gene. Tissue-specific expression and induction by NGF, protein kinase C, and estrogen
-
Rokaeus, A., Jiang, K., Spyrou, G. & Waschek, J. A. Transcriptional control of the galanin gene. Tissue-specific expression and induction by NGF, protein kinase C, and estrogen. Ann. NY Acad. Sci. 863, 1-13 (1998).
-
(1998)
Ann. NY Acad. Sci.
, vol.863
, pp. 1-13
-
-
Rokaeus, A.1
Jiang, K.2
Spyrou, G.3
Waschek, J.A.4
-
62
-
-
0032489093
-
Orexins and orexin receptors: A family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior
-
Sakurai, T. et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92, 573-585 (1998).
-
(1998)
Cell
, vol.92
, pp. 573-585
-
-
Sakurai, T.1
-
63
-
-
0033529520
-
The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (Orexin) Receptor 2 gene
-
Lin, L., et al. The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (Orexin) Receptor 2 gene. Cell 98, 365-376 (1999).
-
(1999)
Cell
, vol.98
, pp. 365-376
-
-
Lin, L.1
-
64
-
-
0033588184
-
Narcolepsy in orexin knockout mice: Molecular genetics of sleep regulation
-
Chemelli, R. M. et al. Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation. Cell 98, 437-451 (1999).
-
(1999)
Cell
, vol.98
, pp. 437-451
-
-
Chemelli, R.M.1
-
65
-
-
0033038418
-
Interacting appetite-regulating pathways in the hypothalamic regulation of body weight
-
Kalra, S. P. et al. Interacting appetite-regulating pathways in the hypothalamic regulation of body weight. Endocr. Rev. 1, 68-100 (1999).
-
(1999)
Endocr. Rev.
, vol.1
, pp. 68-100
-
-
Kalra, S.P.1
-
66
-
-
0033613251
-
Altered anxiety and weight gain in corticotropin-releasing-hormone-binding protein-deficient mice
-
Karolyi, I.J. et al. Altered anxiety and weight gain in corticotropin-releasing-hormone-binding protein-deficient mice. Proc. Natl Acad. Sci. USA 96, 11595-11600 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, pp. 11595-11600
-
-
Karolyi, I.J.1
-
67
-
-
0032962859
-
Reduced satiating effect of d-fenfluramine in serotonin 5-HT (2C) receptor mutant mice
-
Vickers, S. P., Clifton, P.G., Dourish, C. T. & Tecott, L. H. Reduced satiating effect of d-fenfluramine in serotonin 5-HT (2C) receptor mutant mice. Psychopharmacology 143, 309-314 (1999).
-
(1999)
Psychopharmacology
, vol.143
, pp. 309-314
-
-
Vickers, S.P.1
Clifton, P.G.2
Dourish, C.T.3
Tecott, L.H.4
-
68
-
-
0032881287
-
Activation of hypothalamic serotonin receptors reduced intake of dietary fat and protein but not carbohydrate
-
Smith, B. K., York, D. A. & Bray, G. A. Activation of hypothalamic serotonin receptors reduced intake of dietary fat and protein but not carbohydrate. Am. J. Physiol 277, R802-R811 (1999).
-
(1999)
Am. J. Physiol
, vol.277
-
-
Smith, B.K.1
York, D.A.2
Bray, G.A.3
-
69
-
-
0030876952
-
Valvular heart disease associated with fenfluramine-phentermine
-
Connolly, H. M. et al. Valvular heart disease associated with fenfluramine-phentermine. N. Engl. J. Med. 337, 581-588 (1997).
-
(1997)
N. Engl. J. Med.
, vol.337
, pp. 581-588
-
-
Connolly, H.M.1
-
70
-
-
0033162130
-
Serial echocardiographic and clinical evaluation of valvular regurgitation before, during, and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine
-
Ryan, D. H. et al. Serial echocardiographic and clinical evaluation of valvular regurgitation before, during, and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermine. Obes. Res. 7, 313-322 (1999).
-
(1999)
Obes. Res.
, vol.7
, pp. 313-322
-
-
Ryan, D.H.1
-
71
-
-
0033600538
-
Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension
-
Rothman, R. B., Ayestas, M. A., Dersch, C. M., & Baumann, M. H. Aminorex, fenfluramine, and chlorphentermine are serotonin transporter substrates. Implications for primary pulmonary hypertension. Circulation 100, 869-875 (1999).
-
(1999)
Circulation
, vol.100
, pp. 869-875
-
-
Rothman, R.B.1
Ayestas, M.A.2
Dersch, C.M.3
Baumann, M.H.4
-
72
-
-
0033305789
-
Identification of a three-amino acid deletion in the alpha2B-adrenergic receptor that is associated with reduced basal metabolic rate in obese subjects
-
Heinonen, P. et al. Identification of a three-amino acid deletion in the alpha2B-adrenergic receptor that is associated with reduced basal metabolic rate in obese subjects. J. Clin. Endocrinol. Metab. 84, 2429-2433 (1999).
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 2429-2433
-
-
Heinonen, P.1
-
73
-
-
0029401366
-
Dopamine receptor subtype agonists and feeding behavior
-
Terry, P., Gilbert, D. B. & Cooper, S. J. Dopamine receptor subtype agonists and feeding behavior. Obes. Res. 3, 5155 (1995).
-
(1995)
Obes. Res.
, vol.3
, pp. 5155
-
-
Terry, P.1
Gilbert, D.B.2
Cooper, S.J.3
-
74
-
-
0030959657
-
Hypothalamic neuronal histamine implications of its homeostatic control of energy metabolism
-
Sakata, S., Yoshimatsu, H. & Kurokawa, M. Hypothalamic neuronal histamine implications of its homeostatic control of energy metabolism. Nutrition 13, 403-411 (1997).
-
(1997)
Nutrition
, vol.13
, pp. 403-411
-
-
Sakata, S.1
Yoshimatsu, H.2
Kurokawa, M.3
-
75
-
-
0033051582
-
Cloning and functional expression of the human histamine H3 receptor
-
Lovenberg, T. W. et al. Cloning and functional expression of the human histamine H3 receptor. Mol. Pharmacol. 55, 1101-1107 (1999).
-
(1999)
Mol. Pharmacol.
, vol.55
, pp. 1101-1107
-
-
Lovenberg, T.W.1
-
76
-
-
0033562469
-
Histamine regulates food intake through modulating noradrenaline release in the para-ventricular nucleus
-
Kurose, Y. &Terashima, Y. Histamine regulates food intake through modulating noradrenaline release in the para-ventricular nucleus. Brain Res. 15, 115-118 (1999).
-
(1999)
Brain Res.
, vol.15
, pp. 115-118
-
-
Kurose, Y.1
Terashima, Y.2
-
77
-
-
0033197543
-
Identification of the major intestinal fatty acid transport protein
-
Stahl, A. et al. Identification of the major intestinal fatty acid transport protein. Mol. Cell 4, 299-308 (1999).
-
(1999)
Mol. Cell
, vol.4
, pp. 299-308
-
-
Stahl, A.1
-
79
-
-
0030925974
-
Obesity and diabetes and the beta-3 adrenergic receptor
-
Danforth, E. Jr & Himms-Hagen, J. H. Obesity and diabetes and the beta-3 adrenergic receptor. Eur. J. Endocrinol. 136, 362-365 (1997).
-
(1997)
Eur. J. Endocrinol.
, vol.136
, pp. 362-365
-
-
Danforth E., Jr.1
Himms-Hagen, J.H.2
-
80
-
-
0032901360
-
Structure and function of the uncoupling protein from brown adipose tissue
-
Klingenberg, M. & Huang, S. G. Structure and function of the uncoupling protein from brown adipose tissue. Biochim. Biophys. Acta 8, 271-296 (1999).
-
(1999)
Biochim. Biophys. Acta
, vol.8
, pp. 271-296
-
-
Klingenberg, M.1
Huang, S.G.2
-
81
-
-
0031019249
-
Uncoupling protein-2: A novel gene linked to obesity and hyperinsulinemia
-
Fleury, C. et al. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nature Genet. 15, 269-272 (1997).
-
(1997)
Nature Genet.
, vol.15
, pp. 269-272
-
-
Fleury, C.1
-
82
-
-
15144356206
-
Cloning and characterization of an uncoupling protein homolog: A potential molecular mediator of human thermogenesis
-
Gimeno, R. E. et al. Cloning and characterization of an uncoupling protein homolog: a potential molecular mediator of human thermogenesis. Diabetes 46, 900-906 (1997).
-
(1997)
Diabetes
, vol.46
, pp. 900-906
-
-
Gimeno, R.E.1
-
83
-
-
0031560941
-
UCP3: An uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue
-
Vidal-Puig, A., Solanes, G., Grujic, D., Flier, J. S. & Lowell, B. B. UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem. Biophys. Res. Commun. 235, 79-82 (1997).
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.235
, pp. 79-82
-
-
Vidal-Puig, A.1
Solanes, G.2
Grujic, D.3
Flier, J.S.4
Lowell, B.B.5
-
84
-
-
0030988140
-
Uncoupling protein-3: A new member of the mitochondrial carrier family with tissue-specific expression
-
Boss, O. et al. Uncoupling protein-3: a new member of the mitochondrial carrier family with tissue-specific expression. FEBS Lett. 408, 39-42 (1997).
-
(1997)
FEBS Lett.
, vol.408
, pp. 39-42
-
-
Boss, O.1
-
85
-
-
0030869755
-
Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin
-
Gong, D. W., He, Y., Karas, M. & Reitman, M. Uncoupling protein-3 is a mediator of thermogenesis regulated by thyroid hormone, beta3-adrenergic agonists, and leptin. J. Biol. Chem. 39, 24129-24132 (1997).
-
(1997)
J. Biol. Chem.
, vol.39
, pp. 24129-24132
-
-
Gong, D.W.1
He, Y.2
Karas, M.3
Reitman, M.4
-
86
-
-
0033525870
-
Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene
-
Elchebly, M. et al. Increased insulin sensitivity and obesity resistance in mice lacking the protein tyrosine phosphatase-1B gene. Science 283, 1544-1548 (1999).
-
(1999)
Science
, vol.283
, pp. 1544-1548
-
-
Elchebly, M.1
-
87
-
-
13144281703
-
Identification of a gene encoding an acyl CoA: Diacylglycerol acyltransferase, a key enzyme in triacyglycerol synthesis
-
Cases, S. et al. Identification of a gene encoding an acyl CoA: diacylglycerol acyltransferase, a key enzyme in triacyglycerol synthesis. Proc. Natl Acad. Sci. USA 95, 13018-13023 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 13018-13023
-
-
Cases, S.1
-
88
-
-
0001765369
-
Androgen treatment of abdominally obese men
-
Marin, P. et al. Androgen treatment of abdominally obese men. Obes. Res. 1, 245-251 (1993).
-
(1993)
Obes. Res.
, vol.1
, pp. 245-251
-
-
Marin, P.1
-
89
-
-
0027102382
-
The effects of testosterone on body composition and metabolism in middle-aged obese men
-
Marin, P. et al. The effects of testosterone on body composition and metabolism in middle-aged obese men. Int. J. Obes. Relat. Metab. Disord. 16, 991-997 (1992).
-
(1992)
Int. J. Obes. Relat. Metab. Disord.
, vol.16
, pp. 991-997
-
-
Marin, P.1
-
90
-
-
0029135296
-
Oral anabolic steroid treatment, but not parenteral androgen treatment, decreases abdominal fat in obese, older men
-
Lovejoy, J. C. et al. Oral anabolic steroid treatment, but not parenteral androgen treatment, decreases abdominal fat in obese, older men. Int. J. Obes. Relat. Metab. Disord. 19, 614-624 (1995).
-
(1995)
Int. J. Obes. Relat. Metab. Disord.
, vol.19
, pp. 614-624
-
-
Lovejoy, J.C.1
-
91
-
-
0033052163
-
Low-dose growth hormone treatment with diet restriction accelerates body fat loss, exerts anabolic effect and improves growth hormone secretory dysfunction in obese adults
-
Kin, K. R. et al. Low-dose growth hormone treatment with diet restriction accelerates body fat loss, exerts anabolic effect and improves growth hormone secretory dysfunction in obese adults. Hormone Res. 51, 78-84 (1999).
-
(1999)
Hormone Res.
, vol.51
, pp. 78-84
-
-
Kin, K.R.1
-
92
-
-
0033305631
-
Differentiation of adipose stromal cells: The roles of glucocorticoids and 11 beta-hydroxysteroid dehydrogenase
-
Bujalska, I. J., Kumar, S., Hewison, M. & Stewart, P. M. Differentiation of adipose stromal cells: the roles of glucocorticoids and 11 beta-hydroxysteroid dehydrogenase. Endocrinology 140, 3188-3196 (1999).
-
(1999)
Endocrinology
, vol.140
, pp. 3188-3196
-
-
Bujalska, I.J.1
Kumar, S.2
Hewison, M.3
Stewart, P.M.4
-
93
-
-
0029401977
-
Topical fat reduction
-
Greenway, F. L. & Bray, G. A. Topical fat reduction. Obes. Res. 3(Suppl. 4), 561S-568S (1995).
-
(1995)
Obes. Res.
, vol.3
, Issue.4 SUPPL.
-
-
Greenway, F.L.1
Bray, G.A.2
|