Neurochemical changes after imbalanced diets suggest a brain circuit mediating anorectic responses to amino acid deficiency in rats

Journal of Nutrition

Volumn 128, Issue 4, 1998, Pages 771-781

  Gietzen, Dorothy W ^a   Erecius, Lesa F ^a   Rogers, Quinton R ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chemosensor; Conditioned aversion; Feeding behavior; Monoamines; Rats

Indexed keywords

BRAIN MONOAMINE; DOPAMINE; NORADRENALIN; SEROTONIN;

AMINO ACID DEFICIENCY; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANOREXIA; ARTICLE; AVERSIVE BEHAVIOR; CHEMORECEPTOR; CONDITIONING; FEEDING BEHAVIOR; FOOD INTAKE; LIMBIC SYSTEM; MALE; NEUROTRANSMISSION; NONHUMAN; NUTRITIONAL DEFICIENCY; RAT; SATIETY; TASTE;

ANIMALIA;

EID: 0031919866     PISSN: 00223166     EISSN: None     Source Type: Journal    
DOI: 10.1093/jn/128.4.771     Document Type: Article

References (48)

1. Bellinger, L. L. & Gietzen, D. W. (1995) Initial hypophagia caused by an imbalanced amino acid diet (IAAD) is abolished in dorsomedial hypothalamic nucleus lesioned (DMNL) rats. Soc. Neurosci. 21: 965 (abs.).
2. Beverly, J. L., Gietzen, D. W. & Rogers, Q. R. (1990) Effect of dietary limiting amino acid in prepyriform cortex on food intake. Am. J. Physiol. 259: R709-R715.
3. Booth, D. A. & Simson, P. C. (1971) Food preferences acquired by association with variations in amino acid nutrition. Q. J. Exp. Psychol. 23: 135-145.
4. Cooper, J. R., Bloom, F. E. & Roth, R. H. (1996) Pharmacology of central catecholamine-containing neurons. In: The Biochemical Basis of Neuropharmaoology, 7th ed., pp. 282-292. Oxford, New York, NY.
5. Cuella, A. C. (1983) Brain Microdissection Techniques. Wiley, New York, NY.
6. Fernstrom, M. H. & Fernstrom, J. D. (1995) Acute tyrosine depletion reduces tyrosine hydroxylation rate in rat central nervous system. Life Sci. 57: 97-102.
7. Gietzen, D. W. (1993) Neural mechanisms in the responses to amino acid deficiency. J. Nutr. 123: 610-625.
8. Gietzen, D. W. & Beverly, J. L. (1992) Clonidine in the prepyriform cortex blocked anorectic response to amino acid imbalance. Am. J. Physiol. 263: R885-R890.
9. Gietzen, D. W., Dixon, K. D., Truong, B. G., Jones, A. C., Barrett, J. A. & Washburn, D. S. (1996) Indispensable amino acid deficiency and increased seizure susceptibility in rats. Am. J. Physiol. 271: R18-R24.
10. 2 noradrenoceptors in the anterior piriform cortex decline with acute amino acid deficiency. Mol. Brain Res. 35: 41-46.
11. Gietzen, D. W., Leung, P.M.B. & Rogers, Q. R. (1986) Norepinephrine and amino acids in prepyriform cortex of rats fed imbalanced amino acid diets. Physiol. & Behav. 36: 1071-1080.
12. Gietzen, D. W., Leung, P.M.B. & Rogers, Q. R. (1989) Dietary amino acid imbalance and neurochemical changes in three hypothalamic areas. Physiol. & Behav. 46: 503-511.
13. Haberly, L. B. & Price, J. L. (1978) Association and commissural fiber systems of the olfactory cortex of the rat. I. Systems originating in the piriform cortex and adjacent areas. J. Comp. Neurol. 178: 711-740.
14. 3 receptor antagonists block anorectic responses to amino acid imbalance. Am. J. Physiol. 259: R627-R636.
15. Hammer, V. A., Gietzen, D. W., Sworts, V. D., Beverly, J. L. & Rogers, Q. R. (1990b) Adrenal hormones and the anorectic response and adaptation of rats to amino acid imbalance. J. Nutr. 120: 1617-1623.
16. Harper, A. E., Benevenga, N. J. & Wolhueter, R. M. (1970) Effects of ingestion of disproportionate amounts of amino acids. Physiol Rev. 50: 428-558.
17. Hawkins, R. A., Mans, A. M. & Biebuyck, J. F. (1982) Amino acid supply to individual cerebral structures in awake and anesthetized rats. Am. J. Physiol. 242: E1-E11.
18. Lane, J. D., Sands, M. P., Freeman, M. E., Cherek, D. R. & Smith, J. E. (1982) Amino acid neurotransmitter utilization in discrete rat brain regions is correlated with conditioned emotional response. Pharmacol. Biochem. Behav. 16: 329-340.
19. Leung, P.M.B. & Rogers, Q. R. (1970) Effect of amino acid imbalance and deficiency on food intake of rats with hypothalamic lesions. Nutr. Rep. Int. 1: 1-10.
20. Leung, P.M.B. & Rogers, Q. R. (1971) Importance of prepyriform cortex in food-intake response of rats to amino acids. Am. J. Physiol. 221: 929-935.
21. Leung, P.M.B. & Rogers, Q. R. (1973) Effect of amygdaloid lesions on dietary intake of disproportionate amounts of amino acids. Physiol. & Behav. 11: 221-226.
22. Leung, P.M.B. & Rogers, Q. R. (1980) Hyperphagia after ventral tegmental lesions and food intake responses of rats fed disproportionate amounts of dietary amino acids. Physiol. & Behav. 25: 457-464.
23. Leung, P.M.B. & Rogers, Q. R. (1987) The effect of amino acids and protein on dietary choice. In: Umami, A Basic Taste (Kawamura, Y. & Kare, M. R., eds.), pp. 565-610. Marcel Dekker, New York, NY.
24. Leung, P.M.B., Rogers, Q. R. & Harper, A. E. (1968) Effect of amino acid imbalance on plasma and tissue free amino acids in the rat. J. Nutr. 96: 303-318.
25. Lindvall, O. & Bjorklund, A. (1978) Organization of catecholamine neurons in the rat central nervous system. In: Handbook of Psychopharmacology (Iversen, L. L, Iversen, S. D. & Snyder, S. H., eds.), vol. 9, pp. 139-231. Plenum Press, New York, NY.
26. Lutz, J., Tews, J. K. & Harper, A. E. (1975) Simulated amino acid imbalance and histidine transport in rat brain slices. Am. J. Physiol. 229: 229-234.
27. Meliza, L. L., Leung, P.M.B. & Rogers, Q. R. (1981) Effect of anterior prepyriform and medial amygdaloid lesions on acquisition of taste-avoidance and response to dietary amino acid imbalance. Physiol. & Behav. 26: 1031-1035.
28. Meliza, L. L., Leung, P.M.B. & Rogers, Q. R. (1983) Cingulate lesions and behavioral adaptation to amino acid imbalanced diets. Physiol. & Behav. 30: 243-246.
29. Miller, R. G., Jr. (1981) Simultaneous Statistical Inference, pp. 67-70. Springer Verlag, New York, NY.
30. Monda, M., Sullo, A., DeLuca, V., Pellicano, M. P. & Viggiano. A. (1997) L-Threonine injection into PPC modifies food intake, lateral hypothalamic activity and sympathetic discharge. Am. J. Physiol. 273: R554-R559.
31. Nasset, E. S., Ridley, P. T. &Schenk, E. A. (1967) Hypothalamic lesions related to ingestion of an imbalanced amino acid diet. Am. J. Physiol. 213: 645-650.
32. Norgren, R. (1983) Afferent interactions of cranial nerves involved in ingestion. J. Auton. Nerv. Syst. 9: 67-77.
33. Norgren, R., Fromentin, G., Feurte, S. & Nicolaidis, S. (1996) Parabrachial lesions disrupt responses of rats to amino acid deficient diets. Eur. Winter Conf. Brain Res. 16: (abs.).
34. Palkovitz, M. (1973) Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res. 59: 449-450.
35. Panksepp, J. A. & Booth, D. A. (1971) Decreased feeding after injections of amino-acids into the hypothalamus. Nature (Lond.) 233: 341-342.
36. Peng, Y., Tews, J. K. & Harper, A. E. (1972) Amino acid imbalance, protein intake, and changes in rat brain and plasma amino acids. Am. J. Physiol. 222: 314-321.
37. Piredda, S. & Gale, K. (1985) A crucial epileptogenic site in the deep prepiriform cortex. Nature (Lond.) 317: 623-625.
38. Price J. L., Slotnick, B. M. & Revial, M.-F. (1991) Olfactory projections to the hypothalamus J. Comp. Neurol. 306: 447-461.
39. Sanahuja, J. C. & Harper, A. E. (1963) Effect of dietary amino acid pattern on plasma amino acid pattern and food intake. Am. J. Physiol. 204: 686-690.
40. Scharrer, E., Baile, C. A. & Mayer, J. (1970) Effect of amino acids and protein on food intake of hyperphagic and recovered aphagic rats. Am. J. Physiol. 218: 400-404.
41. Snedecor, G. W. & Cochran, W. G. (1967) Statistical Methods, 6th ed. Iowa State University Press, Ames, IA.
42. 3 antagonists block aversion to saccharin in an amino acid imbalanced diet. Am. J. Physiol. 268: R1203-R1208.
43. Tews, J. K., Greenwood, J., Pratt, O. E. & Harper, A. E. (1987) Threonine entry into rat brain after diet-induced changes in plasma amino acids. J. Neurochem. 48: 1879-1886.
44. Torii, K., Yokawa, T., Tabuchi, E., Hawkins, R. L., Mori, M., Kondoh, T. & Ono, T. (1996) Recognition of deficient nutrient intake in the brain of rat with L-lysine deficiency monitored by functional magnetic resonance imaging, electrophysiologically and behaviorally. Amino Acids 10: 73-81.
45. Wang, C. X., Erecius, L. F., Beverly, J. L., & Gietzen, D. W. (1997) Effects of amino acid deficiency on monoamines in the anterior piriform cortex of rats. Soc. Neurosci. 23: 400.
46. Wang, Y., Cummings, S. L. & Gietzen, D. W. (1996a) Temporal-spatial pattern of c-fos expression in the rat brain in response to indispensable amino acid deficiency I. The initial recognition phase. Mol. Brain Res. 40: 27-34.
47. Wang, Y., Cummings, S. L. & Gietzen, D. W. (1996b) Temporal-spatial pattern of c-Fos expression in the rat brain in response to indispensable amino acid deficiency II. The learned taste aversion. Mol. Brain Res. 40: 35-41.
48. Wayner, M. J., Ono, T. DeYoung, A. & Barone, F. C. (1975) Effects of essential amino acids on central neurons. Pharmacol. Biochem. Behav. 3: 85-90.