Identification of the major intestinal fatty acid transport protein

Molecular Cell

Volumn 4, Issue 3, 1999, Pages 299-308

  Stahl, Andreas ^a   Hirsch, David J ^a,b   Gimeno, Ruth E ^c   Punreddy, Sandhya ^c   Pei, Ge ^c   Watson, Nicki ^a   Patel, Shraddha ^a   Kotler, Mariana ^a   Raimondi, Alejandra ^c   Tartaglia, Louis A ^c   Lodish, Harvey F ^a,b  

^a WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MILLENNIUM PHARMACEUTICALS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; FATTY ACID BINDING PROTEIN; LONG CHAIN FATTY ACID;

ANIMAL TISSUE; APICAL MEMBRANE; ARTICLE; FATTY ACID TRANSPORT; HUMAN; HUMAN CELL; INTESTINE CELL; MOUSE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SMALL INTESTINE;

ANIMALIA;

EID: 0033197543     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80332-9     Document Type: Article

References (45)

1. Abumrad, N., El-Maghrabi, M.R., Amri, E.Z., Lopez E., and Grimaldi, P.A. (1993). Cloning of a rat adipocyte membrane protein implicated in binding or transport of long-chain fatty acids that is induced during preadipocyte differentiation. J. Biol. Chem. 268, 17665-17668.
2. Abumrad, N., Harmon, C., and Ibrahimi, A. (1998). Membrane transport of long-chain fatty acids: Evidence for a facilitated process. J. Lipid Res. 39, 2309-2318.
3. Agrawal, S., and Zhao, Q. (1998). Antisense therapeutics. Curr. Opin. Chem. Biol. 2, 519-528.
4. Altschul, S.F., Gish, W., Miller, W., Myers, E.W., and Lipman, D.J. (1990). Basic local alignment search tool. J. Mol. Biol. 215, 403-410.
5. Baillie, A.G.S., Coburn, C.T., and Abumrad, N.A. (1996). Reversible binding of long-chain fatty acids to purified FAT, the adipose CD36 homolog. J. Membr. Biol. 153, 75-81.
6. Carey, M.C., Small, D.M., and Bliss, C.M. (1983). Lipid digestion and absorption. Annu. Rev. Physiol. 45, 651-677.
7. Clandinin, M.T., Cheema, S., Field, C.J., Garg, M.L., Venkatraman, J., and Clandinin, T.R. (1991). Dietary fat: Exogenous determination of membrane structure and cell function. FASEB J. 5, 2761-2769.
8. Davidson, M.H., Hauptman, J., DiGirolamo, M., Foreyt, J.P., Halsted, C.H., Heber, D., Heimburger, D.C., Lucas, C.P., Robbins, D.C., Chung, J., and Heymsfield, S.B. (1999). Weight control and risk factor reduction in obese subjects treated for 2 years with orlistat: A randomized controlled trial. JAMA 281, 235-242
9. Ernst, N.D., Obarzanek, E., Clark, M.B., Briefel, R.R., Brown, C.D., and Donato, K. (1997). Cardiovascular health risks related to overweight. J. Am. Diet. Assoc. 97, S47-S51.
10. Faergeman, N.J., Di Russo, C.C., Elberger, A., Knudsen, J., and Black, P.N. (1997). Disruption of the Saccharomyces cerevisiae homologue to the murine fatty acid transport protein impairs uptake and growth on long-chain fatty acids. J. Biol. Chem. 272, 8531-8538.
11. Fitscher, B.A., Riedel, H.D., Young, K.C., and Stremmel, W. (1998). Tissue distribution and cDNA cloning of a human fatty acid transport protein (hsFATP4). Biochim. Biophys. Acta 1443, 381-385.
12. Gewirtz, A.M., Sokol, D.L., and Ratajczak, M.Z. (1998). Nucleic acid therapeutics: State of the art and future prospects. Blood 92, 712-736.
13. Gore, J., Hoinard, C., and Couet, C. (1994). Linoleic acid uptake by isolated enterocytes: Influence of alpha-linolenic acid on absorption. Lipids 29, 701-706.
14. Green, P.H., and Riley, J.W. (1981). Lipid absorption and intestinal lipoprotein formation. Aust. N. Z. J. Med. 11, 84-90.
15. Guerciolini, R. (1997). Mode of action of orlistat. Int. J. Obes. Relat. Metab. Disord. 21, S12-S23.
16. +/glucose cotransporter. Nature 330, 379-381.
17. Hirsch, D., Stahl, A., and Lodish, H.F. (1998). A family of fatty acid transporters conserved from mycobacterium to man. Proc. Natl. Acad. Sci. USA 95, 8625-8629.
18. Lawson, K.D., Middleton, S.J., and Hassall, C.D. (1997). Olestra, a nonabsorbed, noncaloric replacement for dietary fat: A review. Drug Metab. Rev. 29, 651-703.
19. Ling, K.Y., Lee, H.Y., and Hollander, D. (1989). Mechanisms of linoleic acid uptake by rabbit small intestinal brush border membrane vesicles. Lipids 24, 51-55.
20. Mircheff, A.K., and van Corven, E.J. (1990). Isolation of enterocyte membranes. Methods Enzymol. 192, 341-354.
21. +/Pi cotransporter by antisense oligonucleotides. Proc. Natl. Acad. Sci. USA 93, 4903-4906.
22. Pinkus, L.M. (1981). Separation and use of enterocytes. Methods Enzymol. 77, 154-162.
23. Rodriguez-Boulan, E., and Nelson, W.J. (1989). Morphogenesis of the polarized epithelial cell phenotype. Science 245, 718-725.
24. Schaffer, J.E., and Lodish, H.F. (1994). Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein. Cell 79, 427-436.
25. Sfeir, Z., Ibrahimi, A., Amri, E., Grimaldi, P., and Abumrad, N. (1997). Regulation of FAT/CD36 gene expression: Further evidence in support of a role of the protein in fatty acid binding/transport. Prostaglandins Leukot. Essent. Fatty Acids 57, 17-21.
26. Shneider, B.L. (1998). A new era in bile acid transport pathophysiology. J. Pediatr. Gastroenterol. Nutr. 26, 236-237.
27. Sorrentino, D., Stump, D., Potter, B.J., Robinson, R.B., White, R., Kiang, C.L., and Berk, P.D. (1988). Oleate uptake by cardiac myocytes is carrier mediated and involves a 40-kD plasma membrane fatty acid binding protein similar to that in liver, adipose tissue, and gut. J. Clin. Invest. 82, 928-935.
28. Stevens, B.R. (1992). Vertebrate intestine apical membrane mechanisms of organic nutrient transport. Am. J. Physiol. 263, R458-R463.
29. Stremmel, W. (1988a). Fatty acid uptake by isolated rat heart myocytes represents a carrier-mediated transport process. J. Clin. Invest. 81, 844-852.
30. Stremmel, W. (1988b). Uptake of fatty acids by jejunal mucosal cells is mediated by a fatty acid binding membrane protein. J. Clin. Invest. 82, 2001-2010.
31. Stremmel, W. (1989). Mechanism of hepatic fatty acid uptake. J. Hepatol. 9, 374-382.
32. Stremmel, W., Lotz, G., Strohmeyer, G., and Berk, P.D. (1985a). Identification, isolation, and partial characterization of a fatty acid binding protein from rat jejunal microvillous membranes. J. Clin. Invest. 75, 1068-1076.
33. Stremmel, W., Strohmeyer, G., Borchard, F., Kochwa, S., and Berk, P.D. (1985b). Isolation and partial characterization of a fatty acid binding protein in rat liver plasma membranes. Proc. Natl. Acad. Sci. USA 82, 4-8.
34. Stump, D.D., Zhou, S.L., and Berk, P.D. (1993). Comparison of plasma membrane FABP and mitochondrial isoform of aspartate aminotransferase from rat liver. Am. J. Physiol. 265, G894-G902.
35. Suchy, F.J., Sippel, C.J., and Ananthanarayanan, M. (1997). Bile acid transport across the hepatocyte canalicular membrane. FASEB J. 11, 199-205.
36. Thomson, A.B., De Pover, A., Keelan, M., Jarocka-Cyrta, E., and Clandinin, M.T. (1997). Inhibition of lipid absorption as an approach to the treatment of obesity. Methods Enzymol. 286, 3-44.
37. Thorens, B. (1992). Molecular and cellular physiology of GLUT-2, a high-km facilitated diffusion glucose transporter. Int. Rev. Cytol. 137, 209-238.
38. Thorens, B. (1993). Facilitated glucose transporters in epithelial cells. Annu. Rev. Physiol. 55, 591-608.
39. Thorens, B. (1996). Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes. Am. J. Physiol. 270, G541-G553.
40. Tokuyasu, K.T. (1986). Application of cryoultramicrotomy to immunocytochemistry. J. Microsc. 143, 139-149.
41. Tso, P., and Balint, J.A. (1986). Formation and transport of chylomicrons by enterocytes to the lymphatics. Am. J. Physiol. 250, G715-G726.
42. Van Itallie, T.B. (1996). Prevalence of obesity. Endocrinol. Metab. Clin. North Am. 25, 887-905.
43. Velasco, G., Dominguez, P., Shears, S.B., and Lazo, P.S. (1986). Permeability properties of isolated enterocytes from rat small intestine. Biochim. Biophys. Acta 889, 361-365.
44. Verger, R., Aoubala, M., Carriere, F., Ransac, S., Dupuis, L., De Caro, J., Ferrato, F., Douchet, I., Laugier, R., and De Caro, A. (1996). Regulation of lumen fat digestion: Enzymic aspects. Proc. Nutr. Soc. 55, 5-18.
45. Windler, E., and Greten, H. (1989). Intestinal Lipid and Lipoprotein Metabolism (München: W. Zuckschwerdt Verlag).