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Volumn 277, Issue 3 46-3, 1999, Pages

Activation of hypothalamic serotonin receptors reduced intake of dietary fat and protein but not carbohydrate

Author keywords

5 hydroxytryptamine; Fenfluramine; Food intake; Paraventricular nucleus; Preference; Quipazine

Indexed keywords

DEXFENFLURAMINE; FLUOXETINE; METERGOLINE; NORFENFLURAMINE; QUIPAZINE; SEROTONIN; SEROTONIN RECEPTOR;

EID: 0032881287     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1999.277.3.r802     Document Type: Article
Times cited : (59)

References (49)
  • 1
    • 0029400216 scopus 로고
    • Serotonin, eating behavior, and fat intake
    • Blundell, J. E., C. L. Lawton, and J. C. G. Halford. Serotonin, eating behavior, and fat intake. Obes. Res. 3, Suppl. 4: 471S-476S, 1995.
    • (1995) Obes. Res. , vol.3 , Issue.SUPPL. 4
    • Blundell, J.E.1    Lawton, C.L.2    Halford, J.C.G.3
  • 4
    • 0026659561 scopus 로고
    • Impact of dietary fatty acid balance on membrane structure and function of neuronal tissues
    • Clandinin, M. T., M. Suh, and K. Hargreaves. Impact of dietary fatty acid balance on membrane structure and function of neuronal tissues. Adv. Exp. Med. Biol. 318: 197-210, 1992.
    • (1992) Adv. Exp. Med. Biol. , vol.318 , pp. 197-210
    • Clandinin, M.T.1    Suh, M.2    Hargreaves, K.3
  • 5
    • 0028289642 scopus 로고
    • Intraventricular but not intraparaventricular nucleus metergoline elicits feeding in satiated rats
    • Regulatory Integrative Comp. Physiol. 35
    • Coscina, D. V., D. Feifel, J. N. Nobrega, and P. J. Currie. Intraventricular but not intraparaventricular nucleus metergoline elicits feeding in satiated rats. Am. J. Physiol. 266 (Regulatory Integrative Comp. Physiol. 35): R1562-R1567, 1994.
    • (1994) Am. J. Physiol. , vol.266
    • Coscina, D.V.1    Feifel, D.2    Nobrega, J.N.3    Currie, P.J.4
  • 6
    • 0023753427 scopus 로고
    • Increased food intake in satiated rats induced by the 5-HT antagonists methysergide, metergoline and ritanserin
    • Fletcher, P. Increased food intake in satiated rats induced by the 5-HT antagonists methysergide, metergoline and ritanserin. Psychopharmacology (Berl.) 96: 237-242, 1988.
    • (1988) Psychopharmacology (Berl.) , vol.96 , pp. 237-242
    • Fletcher, P.1
  • 7
    • 0024361873 scopus 로고
    • A comparison of the effects of tryptamine and 5-hydroxytryptamine on feeding following injection into the paraventricular nucleus of the hypothalamus
    • Fletcher, P., and I. A. Paterson. A comparison of the effects of tryptamine and 5-hydroxytryptamine on feeding following injection into the paraventricular nucleus of the hypothalamus. Pharmacol. Biochem. Behav. 32: 907-911, 1989.
    • (1989) Pharmacol. Biochem. Behav. , vol.32 , pp. 907-911
    • Fletcher, P.1    Paterson, I.A.2
  • 8
    • 0029400285 scopus 로고
    • Biological actions of drugs affecting serotonin and eating
    • Garattini, S. Biological actions of drugs affecting serotonin and eating. Obes. Res. 3, Suppl. 4: 463S-470S, 1995.
    • (1995) Obes. Res. , vol.3 , Issue.SUPPL. 4
    • Garattini, S.1
  • 9
    • 0027296519 scopus 로고
    • D-Fenfluramine- and D-norfenfluramine-induced hypophagia: Differential mechanisms and involvement of postsynaptic 5-HT receptors
    • Gibson, E. L., A. J. Kennedy, and G. Curzon. D-Fenfluramine- and D-norfenfluramine-induced hypophagia: differential mechanisms and involvement of postsynaptic 5-HT receptors. Eur. J. Pharmacol. 242: 83-90, 1993.
    • (1993) Eur. J. Pharmacol. , vol.242 , pp. 83-90
    • Gibson, E.L.1    Kennedy, A.J.2    Curzon, G.3
  • 10
    • 0027360166 scopus 로고
    • Ritanserin attenuates anorectic, endocrine and thermic responses to D-fenfluramine in human volunteers
    • Goodall, E. M., P. J. Cowen, M. Franklin, and T. Silverstone. Ritanserin attenuates anorectic, endocrine and thermic responses to D-fenfluramine in human volunteers. Psychopharmacology (Berl.) 112: 461-466, 1993.
    • (1993) Psychopharmacology (Berl.) , vol.112 , pp. 461-466
    • Goodall, E.M.1    Cowen, P.J.2    Franklin, M.3    Silverstone, T.4
  • 11
    • 0026567695 scopus 로고
    • Role of 5-HT receptors in the effect of D-fenfluramine on feeding patterns in the rat
    • Grignaschi, G., and R. Samanin. Role of 5-HT receptors in the effect of D-fenfluramine on feeding patterns in the rat. Eur. J. Pharmacol. 212: 287-289, 1992.
    • (1992) Eur. J. Pharmacol. , vol.212 , pp. 287-289
    • Grignaschi, G.1    Samanin, R.2
  • 12
    • 0028985410 scopus 로고
    • 1B receptor mediates the effect of D-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y
    • 1B receptor mediates the effect of D-fenfluramine on eating caused by intra-hypothalamic injection of neuropeptide Y. Eur. J. Pharmacol. 274: 221-224, 1995.
    • (1995) Eur. J. Pharmacol. , vol.274 , pp. 221-224
    • Grignaschi, G.1    Sironi, F.2    Samanin, R.3
  • 13
    • 0022501315 scopus 로고
    • Synergistic effects of dopamine agonists and centrally administered neurotensin on feeding
    • Hawkins, M. F., C. A. Barkemeyer, and R. T. Tulley. Synergistic effects of dopamine agonists and centrally administered neurotensin on feeding. Pharmacol. Biochem. Behav. 24: 1195-1201, 1986.
    • (1986) Pharmacol. Biochem. Behav. , vol.24 , pp. 1195-1201
    • Hawkins, M.F.1    Barkemeyer, C.A.2    Tulley, R.T.3
  • 14
    • 0030798270 scopus 로고    scopus 로고
    • Fluoxetine decreases fat and protein intakes but not carbohydrate intake in male rats
    • Heisler, L. K., R. B. Kanarek, and A. Gerstein. Fluoxetine decreases fat and protein intakes but not carbohydrate intake in male rats. Pharmacol. Biochem. Behav. 58: 767-773, 1997.
    • (1997) Pharmacol. Biochem. Behav. , vol.58 , pp. 767-773
    • Heisler, L.K.1    Kanarek, R.B.2    Gerstein, A.3
  • 15
    • 0023719763 scopus 로고
    • Infusion of the 5-hydroxytryptamine agonists RU24969 and TFMPP into the paraventricular nucleus of the hypothalamus causes hypophagia
    • Hutson, P. H., T. B. Donohoe, and G. Curzon. Infusion of the 5-hydroxytryptamine agonists RU24969 and TFMPP into the paraventricular nucleus of the hypothalamus causes hypophagia. Psychopharmacology (Berl.) 95: 550-552, 1988.
    • (1988) Psychopharmacology (Berl.) , vol.95 , pp. 550-552
    • Hutson, P.H.1    Donohoe, T.B.2    Curzon, G.3
  • 16
    • 0024159514 scopus 로고
    • Peripheral serotonin administration selectively reduces fat intake in rats
    • Kanarek, R. B., and H. Dushkin. Peripheral serotonin administration selectively reduces fat intake in rats. Pharmacol. Biochem. Behav. 31: 113-122, 1988.
    • (1988) Pharmacol. Biochem. Behav. , vol.31 , pp. 113-122
    • Kanarek, R.B.1    Dushkin, H.2
  • 17
    • 0026057084 scopus 로고
    • Dietary influences on the acute effects of anorectic drugs
    • Kanarek, R. B., A. L. Glick, and R. Marks-Kaufman. Dietary influences on the acute effects of anorectic drugs. Physiol. Behav. 49: 149-152, 1991.
    • (1991) Physiol. Behav. , vol.49 , pp. 149-152
    • Kanarek, R.B.1    Glick, A.L.2    Marks-Kaufman, R.3
  • 18
    • 0027460665 scopus 로고
    • Effects of dexfenfluramine treatment on body weight and postprandial thermogenesis in obese subjects
    • Lafreniere, F., J. Lambert, E. Rasio, and O. Serri. Effects of dexfenfluramine treatment on body weight and postprandial thermogenesis in obese subjects. Int. J. Obes. 17: 25-30, 1993.
    • (1993) Int. J. Obes. , vol.17 , pp. 25-30
    • Lafreniere, F.1    Lambert, J.2    Rasio, E.3    Serri, O.4
  • 19
    • 0027281675 scopus 로고
    • 5-HT manipulation and dietary choice: Variable carbohydrate (Polycose) suppression demonstrated only under specific experimental conditions
    • Lawton, C. L., and J. E. Blundell. 5-HT manipulation and dietary choice: variable carbohydrate (Polycose) suppression demonstrated only under specific experimental conditions. Psychopharmacology (Berl.) 112: 375-382, 1993.
    • (1993) Psychopharmacology (Berl.) , vol.112 , pp. 375-382
    • Lawton, C.L.1    Blundell, J.E.2
  • 20
    • 0027482881 scopus 로고
    • 5-HT and carbohydrate suppression: Effects of 5-HT antagonists on the action of D-fenfluramine and DOI
    • Lawton, C. L., and J. E. Blundell. 5-HT and carbohydrate suppression: effects of 5-HT antagonists on the action of D-fenfluramine and DOI. Pharmacol. Biochem. Behav. 46: 349-360, 1993.
    • (1993) Pharmacol. Biochem. Behav. , vol.46 , pp. 349-360
    • Lawton, C.L.1    Blundell, J.E.2
  • 21
    • 0031596722 scopus 로고    scopus 로고
    • 1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats
    • 1B) agonist CP-93,129 into the parabrachial nucleus potently and selectively reduces food intake in rats. Psychopharmacology (Berl.) 136: 304-307, 1998.
    • (1998) Psychopharmacology (Berl.) , vol.136 , pp. 304-307
    • Lee, M.D.1    Aloyo, V.J.2    Fluharty, S.J.3    Simansky, K.J.4
  • 22
    • 0015875039 scopus 로고
    • Continued pharmacologic analysis of consummatory behavior in the albino rat
    • Lehr, D., and W. Goldman. Continued pharmacologic analysis of consummatory behavior in the albino rat. Eur. J. Pharmacol. 23: 197-210, 1973.
    • (1973) Eur. J. Pharmacol. , vol.23 , pp. 197-210
    • Lehr, D.1    Goldman, W.2
  • 23
    • 0027166899 scopus 로고
    • Effects of serotonin and the serotonin blocker metergoline on meal patterns and macronutrient selection
    • Leibowitz, S. F., J. T. Alexander, W. K. Cheung, and G. F. Weiss. Effects of serotonin and the serotonin blocker metergoline on meal patterns and macronutrient selection. Pharmacol. Biochem. Behav. 45: 185-194, 1993.
    • (1993) Pharmacol. Biochem. Behav. , vol.45 , pp. 185-194
    • Leibowitz, S.F.1    Alexander, J.T.2    Cheung, W.K.3    Weiss, G.F.4
  • 24
    • 0023723068 scopus 로고
    • Hypothalamic serotonin: Pharmacological, biochemical, and behavioral analyses of its feeding-suppressive action
    • Leibowitz, S. F., G. F. Weiss, and G. Shor-Posner. Hypothalamic serotonin: pharmacological, biochemical, and behavioral analyses of its feeding-suppressive action. Clin. Neuropharmacol. 11, Suppl. 1: S51-S71, 1988.
    • (1988) Clin. Neuropharmacol. , vol.11 , Issue.SUPPL. 1
    • Leibowitz, S.F.1    Weiss, G.F.2    Shor-Posner, G.3
  • 25
    • 0025652256 scopus 로고
    • Medial hypothalamic nuclei mediate serotonin's inhibitory effect on feeding behavior
    • Leibowitz, S. F., G. F. Weiss, and J. S. Suh. Medial hypothalamic nuclei mediate serotonin's inhibitory effect on feeding behavior. Pharmacol. Biochem. Behav. 37: 735-742, 1990.
    • (1990) Pharmacol. Biochem. Behav. , vol.37 , pp. 735-742
    • Leibowitz, S.F.1    Weiss, G.F.2    Suh, J.S.3
  • 26
    • 0024435368 scopus 로고
    • Medial hypothalamic serotonin: Role in circadian patterns of feeding and macronutrient selection
    • Leibowitz, S. F., G. F. Weiss, U. A. Walsh, and D. Viswanath. Medial hypothalamic serotonin: role in circadian patterns of feeding and macronutrient selection. Brain Res. 503: 132-140, 1989.
    • (1989) Brain Res. , vol.503 , pp. 132-140
    • Leibowitz, S.F.1    Weiss, G.F.2    Walsh, U.A.3    Viswanath, D.4
  • 27
    • 0000256212 scopus 로고
    • Metergoline blocks the feeding response to enterostatin
    • Lin, L., and D. A. York. Metergoline blocks the feeding response to enterostatin (Abstract). Appetite 23: 313, 1994.
    • (1994) Appetite , vol.23 , pp. 313
    • Lin, L.1    York, D.A.2
  • 28
    • 0031815193 scopus 로고    scopus 로고
    • Chronic ingestion of dietary fat is a prerequisite for inhibition of feeding by enterostatin
    • Regulatory Integrative Comp. Physiol. 44
    • Lin, L., and D. A. York. Chronic ingestion of dietary fat is a prerequisite for inhibition of feeding by enterostatin. Am. J. Physiol. 275 (Regulatory Integrative Comp. Physiol. 44): R619-R623, 1998.
    • (1998) Am. J. Physiol. , vol.275
    • Lin, L.1    York, D.A.2
  • 29
    • 0032527896 scopus 로고    scopus 로고
    • Absence of fenfluramine-induced anorexia and reduced c-fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice
    • Lucas, J. J., A. Yamamoto, K. Scearce-Levie, F. Saudou, and R. Hen. Absence of fenfluramine-induced anorexia and reduced c-fos induction in the hypothalamus and central amygdaloid complex of serotonin 1B receptor knock-out mice. J. Neurosci. 18: 5537-5544, 1998.
    • (1998) J. Neurosci. , vol.18 , pp. 5537-5544
    • Lucas, J.J.1    Yamamoto, A.2    Scearce-Levie, K.3    Saudou, F.4    Hen, R.5
  • 30
    • 0025967381 scopus 로고
    • Effects of repeated administration of serotonergic agonists on diet selection and body weight in rats
    • Luo, S., and E. T. S. Li. Effects of repeated administration of serotonergic agonists on diet selection and body weight in rats. Pharmacol. Biochem. Behav. 38: 495-500, 1991.
    • (1991) Pharmacol. Biochem. Behav. , vol.38 , pp. 495-500
    • Luo, S.1    E T S, L.2
  • 34
    • 0026668214 scopus 로고
    • Effects of a low-fat diet on brain serotonergic responsivity in cynomolgus monkeys
    • Muldoon, M. F., J. R. Kaplan, S. B. Manuck, and J. J. Mann. Effects of a low-fat diet on brain serotonergic responsivity in cynomolgus monkeys. Biol. Psychiatry 31: 739-742, 1992.
    • (1992) Biol. Psychiatry , vol.31 , pp. 739-742
    • Muldoon, M.F.1    Kaplan, J.R.2    Manuck, S.B.3    Mann, J.J.4
  • 35
    • 0026688461 scopus 로고
    • The effect of dietary fat on diet selection may involve central serotonin
    • Regulatory Integrative Comp. Physiol. 32
    • Mullen, B. J., and R. J. Martin. The effect of dietary fat on diet selection may involve central serotonin. Am. J. Physiol. 263 (Regulatory Integrative Comp. Physiol. 32): R559-R563, 1992.
    • (1992) Am. J. Physiol. , vol.263
    • Mullen, B.J.1    Martin, R.J.2
  • 36
    • 0020025311 scopus 로고
    • Differential effects of amphetamine and fenfluramine on dietary self-selection in rats
    • Orthen-Gambill, N., and R. B. Kanarek. Differential effects of amphetamine and fenfluramine on dietary self-selection in rats. Pharmacol. Biochem. Behav. 16: 303-309, 1982.
    • (1982) Pharmacol. Biochem. Behav. , vol.16 , pp. 303-309
    • Orthen-Gambill, N.1    Kanarek, R.B.2
  • 37
    • 0031590705 scopus 로고    scopus 로고
    • Altered serotonin function in suicide: Evidence from platelet and neuroendocrine studies
    • Pandey, G. N. Altered serotonin function in suicide: evidence from platelet and neuroendocrine studies. Ann. NY Acad. Sci. 836: 182-200, 1997.
    • (1997) Ann. NY Acad. Sci. , vol.836 , pp. 182-200
    • Pandey, G.N.1
  • 38
    • 0021871280 scopus 로고
    • Comparison of the effects of fenfluramine and other anorectic agents in different feeding and drinking paradigms in rats
    • Rowland, N. E., S. M. Antelman, and T. J. Bartness. Comparison of the effects of fenfluramine and other anorectic agents in different feeding and drinking paradigms in rats. Life Sci. 36: 2295-2300, 1985.
    • (1985) Life Sci. , vol.36 , pp. 2295-2300
    • Rowland, N.E.1    Antelman, S.M.2    Bartness, T.J.3
  • 39
    • 0020524640 scopus 로고
    • The distribution and cells of origin of serotonergic inputs to the paraventricular and supraoptic nuclei of the rat
    • Sawchenko, P. E., L. W. Swanson, H. W. M. Steinbusch, and A. A. J. Verhofstad. The distribution and cells of origin of serotonergic inputs to the paraventricular and supraoptic nuclei of the rat. Brain Res. 277: 355-360, 1983.
    • (1983) Brain Res. , vol.277 , pp. 355-360
    • Sawchenko, P.E.1    Swanson, L.W.2    Steinbusch, H.W.M.3    Verhofstad, A.A.J.4
  • 41
  • 43
    • 0032078052 scopus 로고    scopus 로고
    • Chronic D-fenfluramine treatment reduces fat intake independent of macronutrient preference
    • Smith, B. K., D. A. York, and G. A. Bray. Chronic D-fenfluramine treatment reduces fat intake independent of macronutrient preference. Pharmacol. Biochem. Behav. 60: 105-114, 1998.
    • (1998) Pharmacol. Biochem. Behav. , vol.60 , pp. 105-114
    • Smith, B.K.1    York, D.A.2    Bray, G.A.3
  • 44
    • 0024372037 scopus 로고
    • Increased food intake and carbohydrate preference in the rat following treatment with the serotonin antagonist metergoline
    • Stallone, D., and S. Nicolaidis. Increased food intake and carbohydrate preference in the rat following treatment with the serotonin antagonist metergoline. Neurosci. Lett. 102: 319-324, 1989.
    • (1989) Neurosci. Lett. , vol.102 , pp. 319-324
    • Stallone, D.1    Nicolaidis, S.2
  • 45
    • 0025611304 scopus 로고
    • Impact of hypothalamic D-norfenfluramine and peripheral D-fenfluramine injection on macronutrient intake in the rat
    • Weiss, G. F., N. Rogacki, A. Fueg, D. Buchen, and S. F. Leibowitz. Impact of hypothalamic D-norfenfluramine and peripheral D-fenfluramine injection on macronutrient intake in the rat. Brain Res. Bull. 25: 849-859, 1990.
    • (1990) Brain Res. Bull. , vol.25 , pp. 849-859
    • Weiss, G.F.1    Rogacki, N.2    Fueg, A.3    Buchen, D.4    Leibowitz, S.F.5
  • 47
    • 0017762393 scopus 로고
    • Fenfluramine and fluoxetine spare protein consumption while suppressing caloric intake by rats
    • Wurtman, J. J., and R. J. Wurtman. Fenfluramine and fluoxetine spare protein consumption while suppressing caloric intake by rats. Science 198: 1178-1180, 1977.
    • (1977) Science , vol.198 , pp. 1178-1180
    • Wurtman, J.J.1    Wurtman, R.J.2
  • 48
    • 0022495372 scopus 로고
    • Carbohydrate craving, obesity and brain serotonin
    • Wurtman, J. J., and R. J. Wurtman. Carbohydrate craving, obesity and brain serotonin. Appetite 7, Suppl.: 99-103, 1986.
    • (1986) Appetite , vol.7 , Issue.SUPPL. , pp. 99-103
    • Wurtman, J.J.1    Wurtman, R.J.2
  • 49
    • 0001634109 scopus 로고
    • Brain amine responses to peripheral enterostatin
    • York, D. A., J. Waggener, and G. A. Bray. Brain amine responses to peripheral enterostatin (Abstract). Int. J. Obes. 18: 102, 1994.
    • (1994) Int. J. Obes. , vol.18 , pp. 102
    • York, D.A.1    Waggener, J.2    Bray, G.A.3


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