메뉴 건너뛰기




Volumn 22, Issue 2, 1999, Pages 203-206

DNA methylation represses transcription in vivo

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE PHOSPHORIBOSYLTRANSFERASE; BETA GLOBIN; CIS ACTING ELEMENT; TRANS ACTING FACTOR;

EID: 0032992224     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/9727     Document Type: Article
Times cited : (302)

References (28)
  • 1
    • 0029126403 scopus 로고
    • DNA methylation in early development
    • Razin, A. & Shemer, R. DNA methylation in early development. Hum. Mol. Genet. 4, 1751-1755 (1995).
    • (1995) Hum. Mol. Genet. , vol.4 , pp. 1751-1755
    • Razin, A.1    Shemer, R.2
  • 2
    • 0020486108 scopus 로고
    • Substrate and sequence specificity of a eukaryotic DNA methylase
    • Gruenbaum, Y., Cedar, H. & Razin, A. Substrate and sequence specificity of a eukaryotic DNA methylase. Nature 292, 620-622 (1982).
    • (1982) Nature , vol.292 , pp. 620-622
    • Gruenbaum, Y.1    Cedar, H.2    Razin, A.3
  • 3
    • 0022538380 scopus 로고
    • Muscle-specific activation of a methylated chimeric actin gene
    • Yisraeli, J. et al. Muscle-specific activation of a methylated chimeric actin gene. Cell 46, 409-416 (1986).
    • (1986) Cell , vol.46 , pp. 409-416
    • Yisraeli, J.1
  • 4
    • 0020624202 scopus 로고
    • DNA methylation and the regulation of the globin gene expression
    • Busslinger, M., Hurst, J. & Flavell, R.A. DNA methylation and the regulation of the globin gene expression. Cell 34, 197-206 (1983).
    • (1983) Cell , vol.34 , pp. 197-206
    • Busslinger, M.1    Hurst, J.2    Flavell, R.A.3
  • 5
    • 0023780629 scopus 로고
    • Effect of in vitro DNA methylation on β globin gene expression
    • Yisraeli, J., Frank, D., Razin, A. & Cedar, H. Effect of in vitro DNA methylation on β globin gene expression. Proc. Natl Acad. Sci. USA 85, 4638-4642 (1988).
    • (1988) Proc. Natl Acad. Sci. USA , vol.85 , pp. 4638-4642
    • Yisraeli, J.1    Frank, D.2    Razin, A.3    Cedar, H.4
  • 6
    • 0030880815 scopus 로고    scopus 로고
    • DNA methylation can activate Xist expression and silence X-linked genes
    • Panning B. & Jaenisch, R. DNA methylation can activate Xist expression and silence X-linked genes. Cell 90, 907-916 (1997).
    • (1997) Cell , vol.90 , pp. 907-916
    • Panning, B.1    Jaenisch, R.2
  • 7
    • 0028786951 scopus 로고
    • Loss of methylation activates Xists in somatic but not in embryonic cells
    • Beard, C., Li, E. & Jaenisch, R. Loss of methylation activates Xists in somatic but not in embryonic cells. Genes Dev. 9, 2325-2334 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 2325-2334
    • Beard, C.1    Li, E.2    Jaenisch, R.3
  • 8
    • 0027378582 scopus 로고
    • Role for DNA methylation in genomic imprinting
    • Li, E., Beard, C. & Jaenisch, R. Role for DNA methylation in genomic imprinting. Nature 366, 362-365 (1993).
    • (1993) Nature , vol.366 , pp. 362-365
    • Li, E.1    Beard, C.2    Jaenisch, R.3
  • 9
    • 0031662164 scopus 로고    scopus 로고
    • Transcription of IAP endogenous retrovirus is constrained by cytosine methylation
    • Walsh, C.P., Chaillet, J.R. & Bestor, T.H. Transcription of IAP endogenous retrovirus is constrained by cytosine methylation. Nature Genet. 20, 116-117 (1998).
    • (1998) Nature Genet. , vol.20 , pp. 116-117
    • Walsh, C.P.1    Chaillet, J.R.2    Bestor, T.H.3
  • 10
    • 0030038608 scopus 로고    scopus 로고
    • A role for nuclear NF-κB in B-cell-specific demethylation of the Igκ locus
    • Kirillov, A. et al. A role for nuclear NF-κB in B-cell-specific demethylation of the Igκ locus. Nature Genet. 13, 435-441 (1996).
    • (1996) Nature Genet. , vol.13 , pp. 435-441
    • Kirillov, A.1
  • 11
    • 0028328632 scopus 로고
    • B-cell specific demethylation: A new role for the intronic κ-chain enhancer sequence
    • Lichtenstein, M., Keini, G., Cedar, H. & Bergman, Y. B-cell specific demethylation: a new role for the intronic κ-chain enhancer sequence. Cell 76, 913-923 (1994).
    • (1994) Cell , vol.76 , pp. 913-923
    • Lichtenstein, M.1    Keini, G.2    Cedar, H.3    Bergman, Y.4
  • 12
    • 0028104109 scopus 로고
    • Sp1 elements protect a CpG island from de novo methylation
    • Brandeis, M. et al. Sp1 elements protect a CpG island from de novo methylation. Nature 371, 435-438 (1994).
    • (1994) Nature , vol.371 , pp. 435-438
    • Brandeis, M.1
  • 13
    • 0027960055 scopus 로고
    • Sp1 sites in the mouse Aprt gene promoter are required to prevent methylation of the CpG island
    • Macleod, D., Charlton, J., Mullins, J. & Bird, A.P. Sp1 sites in the mouse Aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev. 8, 2282-2292 (1994).
    • (1994) Genes Dev. , vol.8 , pp. 2282-2292
    • Macleod, D.1    Charlton, J.2    Mullins, J.3    Bird, A.P.4
  • 14
    • 0028097981 scopus 로고
    • High resolution analysis fo the human hypoxanthine phosphoribosyltransferase gene 5′ region on the active and inactive X chromosomes: Correlation with binding sites for transcription factors
    • Hornstra, I. & Yang, T.P. High resolution analysis fo the human hypoxanthine phosphoribosyltransferase gene 5′ region on the active and inactive X chromosomes: correlation with binding sites for transcription factors. Mol. Cell. Biol. 14, 1419-1430 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 1419-1430
    • Hornstra, I.1    Yang, T.P.2
  • 15
    • 0026505117 scopus 로고
    • The involvement of demethylation in the myeloid-specific function of the mouse M lysozyme gene downstream enhancer
    • Klages, S., Möllers, B. & Renkawitz, R. The involvement of demethylation in the myeloid-specific function of the mouse M lysozyme gene downstream enhancer. Nucleic Acids Res. 20, 1925-1932 (1992).
    • (1992) Nucleic Acids Res. , vol.20 , pp. 1925-1932
    • Klages, S.1    Möllers, B.2    Renkawitz, R.3
  • 16
    • 0028874703 scopus 로고
    • Methylation of the mouse M-lysozyme downstream enhancer inhibits heterotetrameric GABP binding
    • Nickel, J., Short, M.L., Schmitz, A., Eggert, M. & Renkawitz, R. Methylation of the mouse M-lysozyme downstream enhancer inhibits heterotetrameric GABP binding. Nucleic Acids Res. 23, 4785-4792 (1995).
    • (1995) Nucleic Acids Res. , vol.23 , pp. 4785-4792
    • Nickel, J.1    Short, M.L.2    Schmitz, A.3    Eggert, M.4    Renkawitz, R.5
  • 17
    • 0028059099 scopus 로고
    • Deletion of a DNA polymerase β gene segment in T cell using cell type specific gene targeting
    • Gu, H., Marth, J.D., Orban, P.C., Mossman, H. & Rajewsky, K. Deletion of a DNA polymerase β gene segment in T cell using cell type specific gene targeting. Science 265, 103-106 (1994).
    • (1994) Science , vol.265 , pp. 103-106
    • Gu, H.1    Marth, J.D.2    Orban, P.C.3    Mossman, H.4    Rajewsky, K.5
  • 18
    • 0032030846 scopus 로고    scopus 로고
    • Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site specific recombinase
    • Lallemand, Y., Luria, V., Haffner-Krausz, R. & Lonai, P. Maternally expressed PGK-Cre transgene as a tool for early and uniform activation of the Cre site specific recombinase Transgenic Res. 7, 105-112 (1998).
    • (1998) Transgenic Res. , vol.7 , pp. 105-112
    • Lallemand, Y.1    Luria, V.2    Haffner-Krausz, R.3    Lonai, P.4
  • 19
    • 0029155706 scopus 로고
    • Inducible gene targeting in mice
    • Kuhn, R., Schwenk, F., Aguet, M. & Rajewsky, K. Inducible gene targeting in mice. Science 269, 1427-1429 (1995).
    • (1995) Science , vol.269 , pp. 1427-1429
    • Kuhn, R.1    Schwenk, F.2    Aguet, M.3    Rajewsky, K.4
  • 21
    • 0032574977 scopus 로고    scopus 로고
    • Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex
    • Nan, X. et al. Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex. Nature 393, 386-389 (1998).
    • (1998) Nature , vol.393 , pp. 386-389
    • Nan, X.1
  • 22
    • 0031837109 scopus 로고    scopus 로고
    • Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription
    • Jones, P.L. et al. Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription. Nature Genet. 19, 187-191 (1998).
    • (1998) Nature Genet. , vol.19 , pp. 187-191
    • Jones, P.L.1
  • 23
    • 0032572782 scopus 로고    scopus 로고
    • DNA methylation models histone acetylation
    • Eden, S., Hashimshony, T., Keshet, I. & Cedar, H. DNA methylation models histone acetylation. Mature 394, 842 (1998).
    • (1998) Mature , vol.394 , pp. 842
    • Eden, S.1    Hashimshony, T.2    Keshet, I.3    Cedar, H.4
  • 24
    • 0030572637 scopus 로고    scopus 로고
    • DNA demethylation in vitro: Involvement of RNA
    • Weiss, A., Keshet, I., Razin, A. & Cedar, H. DNA demethylation in vitro: involvement of RNA. Cell 86, 709-718 (1996).
    • (1996) Cell , vol.86 , pp. 709-718
    • Weiss, A.1    Keshet, I.2    Razin, A.3    Cedar, H.4
  • 25
    • 0030840954 scopus 로고    scopus 로고
    • Cytosine methylation and the ecology of intragenomic parasites
    • Yoder, J.A., Walsh, C.P. & Bestor, T.H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 13, 335-340 (1997).
    • (1997) Trends Genet. , vol.13 , pp. 335-340
    • Yoder, J.A.1    Walsh, C.P.2    Bestor, T.H.3
  • 26
    • 0032901199 scopus 로고    scopus 로고
    • Cytosine methylation and mammalian development
    • Walsh, C.P. & Bestor, T.H. Cytosine methylation and mammalian development. Genes Dev. 13, 25-34 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 25-34
    • Walsh, C.P.1    Bestor, T.H.2
  • 28
    • 0023605130 scopus 로고
    • Mapping of gene transcripts by nuclease protection assays and cDNA primer extension
    • Calzone, F.J., Britten, R.J. & Davidson, E.H. Mapping of gene transcripts by nuclease protection assays and cDNA primer extension. Methods Enzymol. 152, 611-632 (1987).
    • (1987) Methods Enzymol. , vol.152 , pp. 611-632
    • Calzone, F.J.1    Britten, R.J.2    Davidson, E.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.