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Volumn 6, Issue 1, 2000, Pages 41-48

Signals leading to apoptosis-dependent inhibition of neovascularization by thrombospondin-1

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; CASPASE; MITOGEN ACTIVATED PROTEIN KINASE; THROMBOSPONDIN 1;

EID: 0342445431     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/71517     Document Type: Article
Times cited : (902)

References (48)
  • 1
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan, D. & Folkman, J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86, 353-364 (1996).
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 3
    • 0032568607 scopus 로고    scopus 로고
    • A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1
    • Volpert, O.V., Lawler, J. & Bouck, N.P. A human fibrosarcoma inhibits systemic angiogenesis and the growth of experimental metastases via thrombospondin-1. Proc. Natl. Acad. Sci. USA 95, 6343-6348 (1998)
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6343-6348
    • Volpert, O.V.1    Lawler, J.2    Bouck, N.P.3
  • 4
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • O'Reilly, M.S. et al. Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma. Cell 79, 315-328 (1994).
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1
  • 5
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • O'Reilly, M.S. et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 88, 277-285 (1997).
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.S.1
  • 6
    • 0031469819 scopus 로고    scopus 로고
    • Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance
    • Boehm, T., Folkman, J., Browder, T. & O'Reilly, M.S. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 390, 404-407 (1997).
    • (1997) Nature , vol.390 , pp. 404-407
    • Boehm, T.1    Folkman, J.2    Browder, T.3    O'Reilly, M.S.4
  • 7
    • 0030904193 scopus 로고    scopus 로고
    • Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells
    • Guo, N., Krutzsch, H.C., Inman, J.K. & Roberts, D.D. Thrombospondin 1 and type I repeat peptides of thrombospondin 1 specifically induce apoptosis of endothelial cells. Cancer Res. 57, 1735-1742 (1997).
    • (1997) Cancer Res. , vol.57 , pp. 1735-1742
    • Guo, N.1    Krutzsch, H.C.2    Inman, J.K.3    Roberts, D.D.4
  • 8
    • 0032510801 scopus 로고    scopus 로고
    • Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD
    • Claesson-Welsh, L. et al. Angiostatin induces endothelial cell apoptosis and activation of focal adhesion kinase independently of the integrin-binding motif RGD. Proc. Natl. Acad. Sci. USA 95, 5579-5583 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5579-5583
    • Claesson-Welsh, L.1
  • 9
    • 17444390815 scopus 로고    scopus 로고
    • Multiple forms of angiostatin induce apoptosis in endothelial cells
    • Lucas, R. et al. Multiple forms of angiostatin induce apoptosis in endothelial cells. Blood 92, 4730-4741 (1998).
    • (1998) Blood , vol.92 , pp. 4730-4741
    • Lucas, R.1
  • 10
    • 0033597130 scopus 로고    scopus 로고
    • Endostatin induces endothelial cell apoptosis
    • Dhanabal. M. et al. Endostatin induces endothelial cell apoptosis. J. Biol. Chem. 274, 11721-11726 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 11721-11726
    • Dhanabal, M.1
  • 11
    • 0030949341 scopus 로고
    • 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: Possible role for stress-activated protein kinase signaling pathway and Fas expression
    • Yue, T.L. et al. 2-Methoxyestradiol, an endogenous estrogen metabolite, induces apoptosis in endothelial cells and inhibits angiogenesis: possible role for stress-activated protein kinase signaling pathway and Fas expression. Mol. Pharmacol. 51, 951-962 (1992).
    • (1992) Mol. Pharmacol. , vol.51 , pp. 951-962
    • Yue, T.L.1
  • 12
    • 0000331379 scopus 로고    scopus 로고
    • (eds. Goldberg. I.D. & Rosen, E.M.) Birkhauser Verlag, Basel, Switzerland
    • DiPietro, L.A. in Regulation of Angiogenesis (eds. Goldberg. I.D. & Rosen, E.M.) 295-313 (Birkhauser Verlag, Basel, Switzerland, 1997).
    • (1997) Regulation of Angiogenesis , pp. 295-313
    • DiPietro, L.A.1
  • 13
    • 0029797025 scopus 로고    scopus 로고
    • Regulation of tumor growth and metastasis by thrombospondin-1
    • Roberts, D.D. Regulation of tumor growth and metastasis by thrombospondin-1. FASEB J. 10, 1183-1191 (1996).
    • (1996) FASEB J. , vol.10 , pp. 1183-1191
    • Roberts, D.D.1
  • 15
    • 12344320716 scopus 로고    scopus 로고
    • Thrombospondin-1 is a major activator of TGF-β1 in vivo
    • Crawford, S.E. et al. Thrombospondin-1 is a major activator of TGF-β1 in vivo. Cell 93, 1159-1170 (1998).
    • (1998) Cell , vol.93 , pp. 1159-1170
    • Crawford, S.E.1
  • 16
    • 0028609624 scopus 로고
    • Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis
    • Weinstat-Saslow, D.L. et al. Transfection of thrombospondin 1 complementary DNA into a human breast carcinoma cell line reduces primary tumor growth, metastatic potential, and angiogenesis. Cancer Res. 54, 6504-6511 (1994).
    • (1994) Cancer Res. , vol.54 , pp. 6504-6511
    • Weinstat-Saslow, D.L.1
  • 17
    • 0030751884 scopus 로고    scopus 로고
    • Thrombospondin-1 suppresses tumorigenesis and angiogenesis in serum- and anchorage-independent NIH 3T3 cells
    • Castle, V.P., Dixit, V.M. & Polverini, P.J. Thrombospondin-1 suppresses tumorigenesis and angiogenesis in serum- and anchorage-independent NIH 3T3 cells. Lab. Invest. 77, 51-61 (1997).
    • (1997) Lab. Invest. , vol.77 , pp. 51-61
    • Castle, V.P.1    Dixit, V.M.2    Polverini, P.J.3
  • 18
    • 0033514927 scopus 로고    scopus 로고
    • Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization
    • Bleuel, K., Popp, S., Fusenig, N.E., Stanbridge, E.J. & Boukamp, P. Tumor suppression in human skin carcinoma cells by chromosome 15 transfer or thrombospondin-1 overexpression through halted tumor vascularization. Proc. Natl. Acad. Sci. USA 96, 2065-2070 (1999).
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 2065-2070
    • Bleuel, K.1    Popp, S.2    Fusenig, N.E.3    Stanbridge, E.J.4    Boukamp, P.5
  • 19
    • 0029562535 scopus 로고
    • Inhibition of angiogenesis by thrombospondin-2
    • Volpert, O.V. et al. Inhibition of angiogenesis by thrombospondin-2. Biochem. Biophys. Res. Comm. 217, 326-332 (1995).
    • (1995) Biochem. Biophys. Res. Comm. , vol.217 , pp. 326-332
    • Volpert, O.V.1
  • 20
    • 0030833817 scopus 로고    scopus 로고
    • CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells
    • Dawson, D.W. et al. CD36 mediates the in vitro inhibitory effects of thrombospondin-1 on endothelial cells. J. Cell Biol. 138, 707-717 (1997).
    • (1997) J. Cell Biol. , vol.138 , pp. 707-717
    • Dawson, D.W.1
  • 21
    • 0025775939 scopus 로고
    • Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets
    • Huang, M.M., Bolen, J.B., Barnwell, J.W., Shattil, S.J. & Brugge, J.S. Membrane glycoprotein IV (CD36) is physically associated with the Fyn, Lyn, and Yes protein-tyrosine kinases in human platelets. Proc. Natl. Acad. Sci. USA 88, 7844-7848 (1991).
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7844-7848
    • Huang, M.M.1    Bolen, J.B.2    Barnwell, J.W.3    Shattil, S.J.4    Brugge, J.S.5
  • 22
    • 0028169889 scopus 로고
    • Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells
    • Bull, H.A., Brickell, P.M. & Dowd, P.M Src-related protein tyrosine kinases are physically associated with the surface antigen CD36 in human dermal microvascular endothelial cells. FEBS Lett. 351, 41-44 (1994).
    • (1994) FEBS Lett. , vol.351 , pp. 41-44
    • Bull, H.A.1    Brickell, P.M.2    Dowd, P.M.3
  • 23
    • 0027290714 scopus 로고
    • Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity
    • Tolsma, S.S. et al. Peptides derived from two separate domains of the matrix protein thrombospondin-1 have anti-angiogenic activity. J Cell Biol. 122, 497-511 (1993).
    • (1993) J Cell Biol. , vol.122 , pp. 497-511
    • Tolsma, S.S.1
  • 24
    • 0030478659 scopus 로고    scopus 로고
    • Apoptosis: Does stress kill?
    • Cosulich, S. & Clarke, P. Apoptosis: does stress kill?. Curr. Biol. 6, 1586-1588 (1996).
    • (1996) Curr. Biol. , vol.6 , pp. 1586-1588
    • Cosulich, S.1    Clarke, P.2
  • 25
    • 0032937879 scopus 로고    scopus 로고
    • Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to fas ligand induction and cell death
    • Le-Niculescu, H. et al. Withdrawal of survival factors results in activation of the JNK pathway in neuronal cells leading to Fas ligand induction and cell death. Mol. Cell. Biol. 19, 751-763 (1999).
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 751-763
    • Le-Niculescu, H.1
  • 26
    • 0347537940 scopus 로고    scopus 로고
    • Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis
    • Verheij, M. et al. Requirement for ceramide-initiated SAPK/JNK signaling in stress-induced apoptosis. Nature 380, 75-79 (1996).
    • (1996) Nature , vol.380 , pp. 75-79
    • Verheij, M.1
  • 27
    • 14444281569 scopus 로고    scopus 로고
    • Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
    • Ichijo, H. et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275, 90-94 (1997).
    • (1997) Science , vol.275 , pp. 90-94
    • Ichijo, H.1
  • 28
    • 0029834762 scopus 로고    scopus 로고
    • Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase
    • Kumar, S. et al. Activation of the HIV-1 long terminal repeat by cytokines and environmental stress requires an active CSBP/p38 MAP kinase. J. Biol. Chem. 271, 30864-30869 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 30864-30869
    • Kumar, S.1
  • 29
    • 0025935924 scopus 로고
    • Assay and purification of naturally occurring inhibitor of angiogenesis
    • Polverini, P.J., Bouck, N.P. & Rastinejad, F. Assay and purification of naturally occurring inhibitor of angiogenesis. Meth. Enzymol. 198, 440-450 (1991).
    • (1991) Meth. Enzymol. , vol.198 , pp. 440-450
    • Polverini, P.J.1    Bouck, N.P.2    Rastinejad, F.3
  • 30
    • 0027305971 scopus 로고
    • Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism
    • Schultz-Cherry, S. & Murphy-Ullrich, J.E. Thrombospondin causes activation of latent transforming growth factor-beta secreted by endothelial cells by a novel mechanism . J. Cell Biol. 122, 923-932 (1993).
    • (1993) J. Cell Biol. , vol.122 , pp. 923-932
    • Schultz-Cherry, S.1    Murphy-Ullrich, J.E.2
  • 31
    • 0032893957 scopus 로고    scopus 로고
    • Decreased angiogenesis and arthritic disease in rabbits treated with an ανβ3 antagonist
    • Storgard, C.M. et al. Decreased angiogenesis and arthritic disease in rabbits treated with an ανβ3 antagonist. J. Clin. Invest. 103, 47-54 (1999).
    • (1999) J. Clin. Invest. , vol.103 , pp. 47-54
    • Storgard, C.M.1
  • 32
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson, M.D., Weil, M. & Raff, M.C. Programmed cell death in animal development. Cell 88, 347-354 (1997).
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 33
    • 0032437256 scopus 로고    scopus 로고
    • Signal transduction pathways that regulate cell survival and cell death
    • Dragovich, T., Rudin, C.M. & Thompson, C.B. Signal transduction pathways that regulate cell survival and cell death. Oncogene 17, 3207-3213 (1998).
    • (1998) Oncogene , vol.17 , pp. 3207-3213
    • Dragovich, T.1    Rudin, C.M.2    Thompson, C.B.3
  • 34
    • 0032963472 scopus 로고    scopus 로고
    • Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression
    • Nor, J.E., Christensen, J., Mooney, D.J. & Polverini, P.J. Vascular endothelial growth factor (VEGF)-mediated angiogenesis is associated with enhanced endothelial cell survival and induction of Bcl-2 expression. Am J. Pathol. 154, 375-384 (1999).
    • (1999) Am J. Pathol. , vol.154 , pp. 375-384
    • Nor, J.E.1    Christensen, J.2    Mooney, D.J.3    Polverini, P.J.4
  • 35
    • 0032952010 scopus 로고    scopus 로고
    • Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal
    • Benjamin, L.E., Golijanin, D., Itin, A., Pode, D. & Keshet, E. Selective ablation of immature blood vessels in established human tumors follows vascular endothelial growth factor withdrawal. J. Clin. Invest. 103, 159-165 (1999).
    • (1999) J. Clin. Invest. , vol.103 , pp. 159-165
    • Benjamin, L.E.1    Golijanin, D.2    Itin, A.3    Pode, D.4    Keshet, E.5
  • 36
    • 0033558798 scopus 로고    scopus 로고
    • VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling
    • Gupta, K. et al. VEGF prevents apoptosis of human microvascular endothelial cells via opposing effects on MAPK/ERK and SAPK/JNK signaling. Exp. Cell Res. 247, 495-504 (1999).
    • (1999) Exp. Cell Res. , vol.247 , pp. 495-504
    • Gupta, K.1
  • 37
    • 0028958025 scopus 로고
    • Src family protein tyrosine kinases and cellular signal transduction pathways
    • Erpel, T. & Courtneidge, S.A. Src family protein tyrosine kinases and cellular signal transduction pathways. Curr. Opin. Cell Biol. 7, 176-182 (1995).
    • (1995) Curr. Opin. Cell Biol. , vol.7 , pp. 176-182
    • Erpel, T.1    Courtneidge, S.A.2
  • 38
    • 0030680941 scopus 로고    scopus 로고
    • Fyn-kinase as a determinant of ethanol sensitivity: Relation to NMDA-receptor function
    • Miyakawa, T. et al. Fyn-kinase as a determinant of ethanol sensitivity: relation to NMDA-receptor function. Science 278, 698-701 (1997).
    • (1997) Science , vol.278 , pp. 698-701
    • Miyakawa, T.1
  • 39
    • 0027092647 scopus 로고
    • Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice
    • Grant, S.G.N. et al. Impaired long-term potentiation, spatial learning, and hippocampal development in fyn mutant mice. Science 258, 1903-1910 (1992).
    • (1992) Science , vol.258 , pp. 1903-1910
    • Grant, S.G.N.1
  • 40
    • 0031015043 scopus 로고    scopus 로고
    • Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases
    • Juo, P., et al. Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases. Mol. Cell. Biol. 17, 24-35 (1997).
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 24-35
    • Juo, P.1
  • 41
    • 0030755579 scopus 로고    scopus 로고
    • The regulation of anoikis: MEKK-1 activation requires cleavage by caspases
    • Cardone, M.H., Salvesen, G.S., Widmann, C., Johnson, G. & Frisch, S.M. The regulation of anoikis: MEKK-1 activation requires cleavage by caspases. Cell 90, 315-323 (1997).
    • (1997) Cell , vol.90 , pp. 315-323
    • Cardone, M.H.1    Salvesen, G.S.2    Widmann, C.3    Johnson, G.4    Frisch, S.M.5
  • 42
    • 0030820875 scopus 로고    scopus 로고
    • Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis
    • Kothakota, S. et al. Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis. Science 278, 294-298 (1997).
    • (1997) Science , vol.278 , pp. 294-298
    • Kothakota, S.1
  • 43
    • 0033602716 scopus 로고    scopus 로고
    • Coordinate induction of the actin cytoskeletal regulatory proteins gelsolin, vasodilator-stimulated phosphoprotein, and profilin during capillary morphogenesis in vitro
    • Salazar, R., Bell, S.E. & Davis, G. E. Coordinate induction of the actin cytoskeletal regulatory proteins gelsolin, vasodilator-stimulated phosphoprotein, and profilin during capillary morphogenesis in vitro. Exp. Cell Res. 249, 22-32 (1999).
    • (1999) Exp. Cell Res. , vol.249 , pp. 22-32
    • Salazar, R.1    Bell, S.E.2    Davis, G.E.3
  • 44
    • 0028670833 scopus 로고
    • Integrin alphaV beta3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
    • Brooks, P.C. et al. Integrin alphaV beta3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 79, 1157-1164 (1994).
    • (1994) Cell , vol.79 , pp. 1157-1164
    • Brooks, P.C.1
  • 45
    • 0030038229 scopus 로고    scopus 로고
    • Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis
    • Stromblad, S., Becker, J.C., Yebra, M., Brooks, P.C. & Cheresh, D.A. Suppression of p53 activity and p21WAF1/CIP1 expression by vascular cell integrin alphaVbeta3 during angiogenesis. J. Clin. Invest. 98, 426-433 (1996).
    • (1996) J. Clin. Invest. , vol.98 , pp. 426-433
    • Stromblad, S.1    Becker, J.C.2    Yebra, M.3    Brooks, P.C.4    Cheresh, D.A.5
  • 46
    • 0028791690 scopus 로고
    • Unraveling immune privilege
    • Streilein, J.W. Unraveling immune privilege. Science 270, 1158-1159 (1995).
    • (1995) Science , vol.270 , pp. 1158-1159
    • Streilein, J.W.1
  • 47
    • 0029834447 scopus 로고    scopus 로고
    • Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases
    • Schlaepfer, D.D. & Hunter, T. Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases. Mol. Cell. Biol. 16, 5623-5633 (1996).
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 5623-5633
    • Schlaepfer, D.D.1    Hunter, T.2
  • 48
    • 0033516477 scopus 로고    scopus 로고
    • A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism
    • Febbraio, M., Abumrad, N.A., Haijar, D.P., Sharma, K., Pearce, S.F.A. & Silverstein, R.L. A null mutation in murine CD36 reveals an important role in fatty acid and lipoprotein metabolism. J. Biol. Chem. 274, 19055-19062 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 19055-19062
    • Febbraio, M.1    Abumrad, N.A.2    Haijar, D.P.3    Sharma, K.4    Pearce, S.F.A.5    Silverstein, R.L.6


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