Post-receptor signal transduction and regulation of 14(R),15(S)-epoxyeicosatrienoic acid (14,15-EET) binding in U-937 cells

Journal of Lipid Mediators and Cell Signalling

Volumn 16, Issue 3, 1997, Pages 155-169

  Wong, Patrick Y K ^a   Lai, Pi Shiang ^a   Shen, Shu Ying ^a   Belosludtsev, Yuri Y ^b   Falck, J R ^b  

^a UMDNJ School of Osteopathic Medicine   (United States)

^b NONE

Author keywords

14(R),15(S) epoxyeicosatrienoic acid binding; Regulation; U 937 cells

Indexed keywords

14,15 EPOXY 5,8,11 ICOSATRIENOIC ACID; BUCLADESINE; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYTOCHROME P450; K 252A; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PERTUSSIS TOXIN; PROTEIN KINASE C INHIBITOR; RADIOLIGAND;

ARACHIDONIC ACID METABOLISM; ARTICLE; BINDING COMPETITION; BINDING SITE; CELL ADHESION; CELL LINE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG INHIBITION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MONOCYTE; PRIORITY JOURNAL; RECEPTOR BINDING; RECEPTOR DENSITY; RECEPTOR DOWN REGULATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STEREOSPECIFICITY;

8,11,14-EICOSATRIENOIC ACID; BINDING SITES; BUCLADESINE; CELL ADHESION; CELL LINE; CHOLERA TOXIN; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOWN-REGULATION; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; ISOQUINOLINES; MONOCYTES; PERTUSSIS TOXIN; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; STEREOISOMERISM; SULFONAMIDES; VIRULENCE FACTORS, BORDETELLA;

EID: 0031194598     PISSN: 09297855     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0929-7855(97)00005-9     Document Type: Article

References (20)

1. Ballou L., Lam B., Wong P.Y.-K., Cheung W.Y. Formation of cis-14,15-oxido-5,8,11-icosatrienoic acid from phosphatidylinositol in human platelets. Proc Natl Acad Sci USA. 84:1987;6990-6994.
2. Berstrom K., Kayganich K., Murphy R.C., Fitzpatrick F.A. Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids. J Biol Chem. 267:1992;3686-3690.
3. Cashman R., Hanks D., Wiener R. Epoxy derivatives of arachidonic acid are potent stimulators of prolactin secretion. Neuroendocrinology. 76:1987;246-251.
4. Catella F., Lawson J.A., Fitzgerald D.J., Fitzgerald G.A. Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension. Proc Natl Acad Sci USA. 87:1990;5893-5897.
5. Chijiwa T., Mishima A., Hagiwara M., Sano M., Hayashi K., Inone T., Naito K., Toshioka T., Hidaka H. Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC 12 D pheochromocytoma cells. J Biol Chem. 265:1990;5267-5272.
6. Falck J.R., Schueler V., Jacobson H.R., Siddhanata A., Pramanik B., Capdevila J. Arachidonate epcxygenase: identification of epoxyeicosatrienoic acids in rabbit kidney. J Lipid Res. 28:1987;840-846.
7. Falck J.R., Yadagiri P., Capdevila J. Synthesis of epoxyeicosatrienoic acid and heteroatom analogs. Methods Enzymol. 187:1990;357-483.
8. Henrick W.L., Falck J.R., Campbell W.B. Inhibition of renin release by 14,15-epoxyeicosatrienoic acid in renal cortical slices. Am J Physiol. 258:1990;E269-274.
9. Hirt D.L., Capdevila J., Falck J.R., Breyer M.D., Jacobson H.R. Cytochrome P-450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct. J Clin Invest. 84:1989;1805-1812.
10. Lambert B., Aublin J.L., Champion S., Haye B., Jacquemin C. Comparative effects of cholera and Bordetella pertussis toxins on cyclic AMP and GTP levels and on lipolysis in rat adipocytes incubated in vitro. FEBS Lett. 181(2):1985;390-396.
11. Lapuerta L., Chacos N., Falck J.R., Jacobson H., Capdevila J. Renal micosomal cytochrome P-450 and the oxidative metabolism of arachidonic acid. Am J Med Sci. 295:1988;275-279.
12. Lin W.-K., Falck J.R., Wong P.Y.-K. Effects of 14,15-epoxyeicosatrienoic acid infusion on blood pressure in normal and hypertensive rats. Biochem Biophys Res Commun. 167:1990;977-981.
13. +2 entry into platelets stimulated by thapsigargin and thrombin. J Biol Chem. 267:1992;19854-19858.
14. Pritchard K., Tota R.R., Stemerman M.V., Wong P.Y.-K. 14,15-Epoxy eicosatrienoic acid promotes endothelial cell dependent adhesion of human monocytic tumor U-937 cells. Biochem Biophys Res Commun. 167:1990;137-142.
15. Pritchard K.A., Wong P.Y.-K, Stemerman M.B. Atherogenic concentration of low density lipoprotein enhance endothehal cell generation of epoxyeicosatrienoic acid products. Am J Pathol. 136:1990;1383-1391.
16. Revtyak G.E., Hughes M.J., Johnson A.R., Campbell W.B. Histamine stimulation of prostagladin and HETE synthesis in human endothelial cells. Am J Physiol. 255:1988;C214-225.
17. +)ATPase. Nature. 317:1985;620-622.
18. Toto R., Siddhanata A., Manna B., Pramanik B., Falck J.R., Capdevila J. Arachidonic acid epoxygenase: detection of epoxyeicosatrienoic acids in human urine. Biochem Biophys Acta. 919:1989;132-139.
19. Wong P.Y.-K., Yan Y.-T., Lin K.-T., Shen S.-Y., Falck J.R. 14(R),15(S)-Epoxyeicosatrienoic acid receptor binding during monocyte and endothelial cell interactions. Atheroscler Rev. 25:1993;101-109.
20. Wong P.Y.-K., Lin K.-T., Yan Y.-T., Ahern D., Iles J., Shen S.-Y., Bhatt R.K., Falck J.R. 14(R),15(S)-Epoxyeicosatrienoic acid (14(R),15(S)-EET) receptor in guinea pig mononuclear cell membranes. J Lipid Mediators. 6:1993;199-208.