-
2
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin, C. H., Miyazono, K., and ten Dijke, P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature (Lond.), 390; 465-471, 1997.
-
(1997)
Nature (Lond.)
, vol.390
, pp. 465-471
-
-
Heldin, C.H.1
Miyazono, K.2
Ten Dijke, P.3
-
3
-
-
0031911356
-
SMADs: Mediators and regulators of TGF-β signaling
-
Kretzschmar, M., and Massagué, J. SMADs: mediators and regulators of TGF-β signaling. Curr. Opin. Genet. Dev., 8: 103-111, 1998.
-
(1998)
Curr. Opin. Genet. Dev.
, vol.8
, pp. 103-111
-
-
Kretzschmar, M.1
Massagué, J.2
-
4
-
-
0030751329
-
Transforming growth factor-β signaling in epithelial cells
-
Hartsough, M. T., and Mulder, K. M. Transforming growth factor-β signaling in epithelial cells. Pharmacol. Ther., 75: 21-41, 1997.
-
(1997)
Pharmacol. Ther.
, vol.75
, pp. 21-41
-
-
Hartsough, M.T.1
Mulder, K.M.2
-
5
-
-
0031059867
-
Involvement of extracellular signal-regulated kinase 2 and stress-activated protein kinase/Jun N-terminal kinase activation by transforming growth factor-β in the negative growth control of breast cancer cells
-
Frey, R. S., and Mulder, K. M. Involvement of extracellular signal-regulated kinase 2 and stress-activated protein kinase/Jun N-terminal kinase activation by transforming growth factor-β in the negative growth control of breast cancer cells. Cancer Res., 57: 628-633, 1997.
-
(1997)
Cancer Res.
, vol.57
, pp. 628-633
-
-
Frey, R.S.1
Mulder, K.M.2
-
6
-
-
0028937610
-
Transforming growth factor-β activation of p44MAPK in proliferating cultures of epithelial cells
-
Hartsough, M. T., and Mulder, K. M. Transforming growth factor-β activation of p44MAPK in proliferating cultures of epithelial cells. J. Biol. Chem., 270: 7117-7124, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 7117-7124
-
-
Hartsough, M.T.1
Mulder, K.M.2
-
7
-
-
0029940355
-
TAB1: An activator of the TAK1 MAPKKK in TGF-β signal transduction
-
Shibuya, H., Yamaguchi, K., Shirakabe, K., Tonegawa, A., Gotoh, Y., Ueno, N., Irie, K., Nishida, E., and Matsumoto, K. TAB1: an activator of the TAK1 MAPKKK in TGF-β signal transduction. Science (Washington DC), 272: 1179-1182, 1996.
-
(1996)
Science (Washington DC)
, vol.272
, pp. 1179-1182
-
-
Shibuya, H.1
Yamaguchi, K.2
Shirakabe, K.3
Tonegawa, A.4
Gotoh, Y.5
Ueno, N.6
Irie, K.7
Nishida, E.8
Matsumoto, K.9
-
8
-
-
0033104505
-
TGF-β induces fibronectin synthesis through ac-Jun N-terminal kinase-dependent, Smad4-independent pathway
-
Hocevar, B. A., Brown, T. L., and Howe, P. H. TGF-β induces fibronectin synthesis through ac-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J., 18: 1345-1356, 1999.
-
(1999)
EMBO J.
, vol.18
, pp. 1345-1356
-
-
Hocevar, B.A.1
Brown, T.L.2
Howe, P.H.3
-
9
-
-
0030773834
-
Opposing BMP and EGF signaling pathways converge on the TGF-β family mediator smad1
-
Kretschmar, M., Doody, J., and Massagué, J. Opposing BMP and EGF signaling pathways converge on the TGF-β family mediator Smad1. Nature (Lond.), 389: 618-922, 1997.
-
(1997)
Nature (Lond.)
, vol.389
, pp. 618-922
-
-
Kretschmar, M.1
Doody, J.2
Massagué, J.3
-
10
-
-
2642605344
-
Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases
-
de Caestecker, M. P., Parks, W. T., Frank, C. J., Castagnino, P., Bottaro, D. P., Roberts, A. B., and Lechleider, R. J. Smad2 transduces common signals from receptor serine-threonine and tyrosine kinases. Genes Dev., 12: 1587-1592, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 1587-1592
-
-
De Caestecker, M.P.1
Parks, W.T.2
Frank, C.J.3
Castagnino, P.4
Bottaro, D.P.5
Roberts, A.B.6
Lechleider, R.J.7
-
11
-
-
0033106484
-
Mechanism of repression of TGFβ/Smad signaling by oncogenic Ras
-
Kretzschmar, M., Doody, J., Timokhina, I., and Massagué, J. A. mechanism of repression of TGFβ/Smad signaling by oncogenic Ras. Genes Dev., 13: 804-816, 1999.
-
(1999)
Genes Dev.
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massagué, J.A.4
-
12
-
-
0032478143
-
Targeted deletion of Smad4 shows it is required for transforming growth factor-β and activin signaling in colorectal cancer cells
-
Zhou, S., Buckhaults, P., Zawel, L., Bunz, F., Riggins, G., Le Dai, J., Kern, S. E., Kinzler, K. W., and Vogelstein, B. Targeted deletion of Smad4 shows it is required for transforming growth factor-β and activin signaling in colorectal cancer cells. Proc. Natl. Acad. Sci. USA, 95: 2412-2416, 1998.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 2412-2416
-
-
Zhou, S.1
Buckhaults, P.2
Zawel, L.3
Bunz, F.4
Riggins, G.5
Le Dai, J.6
Kern, S.E.7
Kinzler, K.W.8
Vogelstein, B.9
-
13
-
-
0030922980
-
Characterization of functional domains within Smad4/DPC4
-
de Caestecker, M. P., Hemmati, P., Larisch-Bloch, S., Ajmera, R., Roberts, A. B., and Lechleider, R. J. Characterization of functional domains within Smad4/DPC4. J. Biol. Chem., 272: 13690-13696, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13690-13696
-
-
De Caestecker, M.P.1
Hemmati, P.2
Larisch-Bloch, S.3
Ajmera, R.4
Roberts, A.B.5
Lechleider, R.J.6
-
14
-
-
0032828502
-
Transforming growth factor-β responsiveness in DPC4/ SMAD4-null cancer cells
-
Dai, J. L., Schutte, M., Bansal, R. K., Wilentz, R. E., Sugar, A. Y., and Kern, S. E. Transforming growth factor-β responsiveness in DPC4/ SMAD4-null cancer cells. Mol. Carcinog., 26: 37-43, 1999.
-
(1999)
Mol. Carcinog.
, vol.26
, pp. 37-43
-
-
Dai, J.L.1
Schutte, M.2
Bansal, R.K.3
Wilentz, R.E.4
Sugar, A.Y.5
Kern, S.E.6
-
15
-
-
0030868250
-
Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-β through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway
-
Atfi, A., Buisine, M., Mazars, A., and Gespach, C. Induction of apoptosis by DPC4, a transcriptional factor regulated by transforming growth factor-β through stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK) signaling pathway. J. Biol. Chem., 272: 24731-24734, 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 24731-24734
-
-
Atfi, A.1
Buisine, M.2
Mazars, A.3
Gespach, C.4
-
16
-
-
0026318253
-
Coordinated regulation of apoptosis and cell proliferation by transforming growth factor-β1 in cultured uterine epithelial cells
-
Rotello, R. J., Leibermann, R. C., Purchio, A. F., and Gerschenson, L. Coordinated regulation of apoptosis and cell proliferation by transforming growth factor-β1 in cultured uterine epithelial cells. Proc. Natl. Acad. Sci. USA, 88: 3412-3415, 1991.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3412-3415
-
-
Rotello, R.J.1
Leibermann, R.C.2
Purchio, A.F.3
Gerschenson, L.4
-
17
-
-
0026584374
-
In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor β1
-
Lin, J. K., and Chou, C. K. In vitro apoptosis in the human hepatoma cell line induced by transforming growth factor β1. Cancer Res., 52: 385-388, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 385-388
-
-
Lin, J.K.1
Chou, C.K.2
-
18
-
-
0026769473
-
Transforming growth factor-β1 induces apoptotic cell death in cultured human gastric carcinoma cells
-
Yanagihara, K., and Tsumuraya, M. Transforming growth factor-β1 induces apoptotic cell death in cultured human gastric carcinoma cells. Cancer Res., 52: 4042-4045, 1992.
-
(1992)
Cancer Res.
, vol.52
, pp. 4042-4045
-
-
Yanagihara, K.1
Tsumuraya, M.2
-
19
-
-
0031843551
-
Transforming growth factor-β-mediated apoptosis in the Ramos B-lymphoma cell line is accompanied by caspase activation and Bcl-xL downregulation
-
Saltzman, A., Munro, R., Searfoss, G., Franks, C., Jaye, M., and Ivashchenko, Y. Transforming growth factor-β-mediated apoptosis in the Ramos B-lymphoma cell line is accompanied by caspase activation and Bcl-xL downregulation. Exp. Cell Res., 242: 244-254, 1998.
-
(1998)
Exp. Cell Res.
, vol.242
, pp. 244-254
-
-
Saltzman, A.1
Munro, R.2
Searfoss, G.3
Franks, C.4
Jaye, M.5
Ivashchenko, Y.6
-
20
-
-
0028575840
-
Regulation of neuronal Bcl2 protein expression and calcium homeostasis by transforming growth factor type β confers wide-ranging protection on rat hippocampal neurons
-
Prehn, J. H. M., Bindokas, V. P., Marcuccilli, C. J., Krajewski, S., Reed, J. C., and Miller, R. J. Regulation of neuronal Bcl2 protein expression and calcium homeostasis by transforming growth factor type β confers wide-ranging protection on rat hippocampal neurons. Proc. Natl. Acad. Sci. USA, 97: 12599-12603, 1994.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 12599-12603
-
-
Prehn, J.H.M.1
Bindokas, V.P.2
Marcuccilli, C.J.3
Krajewski, S.4
Reed, J.C.5
Miller, R.J.6
-
21
-
-
0030812891
-
Transforming growth factor-β protects human hNT cells from degeneration induced by β-amyloid peptide: Involvement of the TGf-β type II receptor
-
Ren, R. F., Hawver, D. B., Kim, R. S., and Flanders, K. C. Transforming growth factor-β protects human hNT cells from degeneration induced by β-amyloid peptide: involvement of the TGf-β type II receptor. Brain Res. Mol. Brain Res., 48: 315-322, 1997.
-
(1997)
Brain Res. Mol. Brain Res.
, vol.48
, pp. 315-322
-
-
Ren, R.F.1
Hawver, D.B.2
Kim, R.S.3
Flanders, K.C.4
-
22
-
-
0030567912
-
Role for Bcl-xL in the regulation of apoptosis by EGF and TGF-β1 in c-myc overexpressing mammary epithelial cells
-
Nass, S. J., Li, M., Amundadottir, L. Ts, Furth, P. A., and Dickson, R. B. Role for Bcl-xL in the regulation of apoptosis by EGF and TGF-β1 in c-myc overexpressing mammary epithelial cells. Biochem. Biophys. Res. Commun., 227: 248-256, 1996.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.227
, pp. 248-256
-
-
Nass, S.J.1
Li, M.2
Amundadottir, L.Ts.3
Furth, P.A.4
Dickson, R.B.5
-
23
-
-
0031945984
-
Inhibition by dexamethasone of transforming growth factor β1-induced apoptosis in rat hepatoma cells: A possible association with Bcl-xL induction
-
Yamamoto, M., Fukuda, K., Miura, N., Suzuki, R., Kido, T., and Komatsu, Y. Inhibition by dexamethasone of transforming growth factor β1-induced apoptosis in rat hepatoma cells: a possible association with Bcl-xL induction. Hepatology, 27: 959-966, 1998.
-
(1998)
Hepatology
, vol.27
, pp. 959-966
-
-
Yamamoto, M.1
Fukuda, K.2
Miura, N.3
Suzuki, R.4
Kido, T.5
Komatsu, Y.6
-
24
-
-
0028359232
-
Development and characterization of nontumorigenic and tumorigenic epithelial cells lines from rat dorsal-lateral prostate
-
Danielpour, D., Kadomatsu, K., Anzano, M. A., Smith, J. M., and Sporn, M. B. Development and characterization of nontumorigenic and tumorigenic epithelial cells lines from rat dorsal-lateral prostate. Cancer Res., 54: 3413-3421, 1994.
-
(1994)
Cancer Res.
, vol.54
, pp. 3413-3421
-
-
Danielpour, D.1
Kadomatsu, K.2
Anzano, M.A.3
Smith, J.M.4
Sporn, M.B.5
-
25
-
-
0029806099
-
Regulation of apoptosis induced by transforming growth factor-β1 in nontumorigenic and tumorigenic rat prostatic epithelial cell lines
-
Hsing, A. Y., Kadomatsu, K., Bonham, M. J., and Danielpour, D. Regulation of apoptosis induced by transforming growth factor-β1 in nontumorigenic and tumorigenic rat prostatic epithelial cell lines. Cancer Res., 56: 5146-5149, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 5146-5149
-
-
Hsing, A.Y.1
Kadomatsu, K.2
Bonham, M.J.3
Danielpour, D.4
-
26
-
-
0026496172
-
TGF-β signals through a heteromeric protein kinase receptor complex
-
Wrana, J. L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X. F., and Massagué, J. TGF-β signals through a heteromeric protein kinase receptor complex. Cell, 71: 1003-1014, 1992.
-
(1992)
Cell
, vol.71
, pp. 1003-1014
-
-
Wrana, J.L.1
Attisano, L.2
Carcamo, J.3
Zentella, A.4
Doody, J.5
Laiho, M.6
Wang, X.F.7
Massagué, J.8
-
27
-
-
0030029703
-
Induction of transforming growth factor-β autocrine activity by all-rrans-retinoic acid and 1α,25-dihydroxyvitamin D3 in NRP-152 rat prostatic epithelial cells
-
Danielpour, D. Induction of transforming growth factor-β autocrine activity by all-rrans-retinoic acid and 1α,25-dihydroxyvitamin D3 in NRP-152 rat prostatic epithelial cells. J. Cell. Physiol., 166: 231-239, 1996.
-
(1996)
J. Cell. Physiol.
, vol.166
, pp. 231-239
-
-
Danielpour, D.1
-
28
-
-
0026334362
-
Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor β
-
Keeton, M. R., Curriden, S. A., van Zonneveld, A. J., and Loskutoff, D. J. Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor β. J. Biol. Chem., 266: 23048-23052, 1991.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 23048-23052
-
-
Keeton, M.R.1
Curriden, S.A.2
Van Zonneveld, A.J.3
Loskutoff, D.J.4
-
29
-
-
0033515587
-
Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor β-induced smad-dependent transcriptional activation
-
Stroschein, S. L., Wang, W., and Luo, K. Cooperative binding of Smad proteins to two adjacent DNA elements in the plasminogen activator inhibitor-1 promoter mediates transforming growth factor β-induced smad-dependent transcriptional activation. J. Biol. Chem., 274: 9431-9441, 1999.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 9431-9441
-
-
Stroschein, S.L.1
Wang, W.2
Luo, K.3
-
30
-
-
0032491478
-
Smad4/DPC4 and Smad3 mediate transforming growth factor-β (TGF-β) signaling through direct binding to a novel TGF-β-responsive element in the human plasminogen activator inhibitor-1 promoter
-
Song, C. Z., Siok, T. E., and Gelehrter, T. D. Smad4/DPC4 and Smad3 mediate transforming growth factor-β (TGF-β) signaling through direct binding to a novel TGF-β-responsive element in the human plasminogen activator inhibitor-1 promoter. J. Biol. Chem., 273: 29287-29290, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29287-29290
-
-
Song, C.Z.1
Siok, T.E.2
Gelehrter, T.D.3
-
31
-
-
0032191407
-
Synergistic cooperation of TFE3 and smad proteins in TGF-β-induced transcription of the plasminogen activator inhibitor-1 gene
-
Hua, X., Liu, X., Ansari, D. O., and Lodish, H. F. Synergistic cooperation of TFE3 and smad proteins in TGF-β-induced transcription of the plasminogen activator inhibitor-1 gene. Genes Dev., 12: 3084-3095, 1998.
-
(1998)
Genes Dev.
, vol.12
, pp. 3084-3095
-
-
Hua, X.1
Liu, X.2
Ansari, D.O.3
Lodish, H.F.4
-
32
-
-
0028360309
-
Induction of a common pathway of apoptosis by staurosporine
-
Bertrand, R., Solary, E., O'Connor, P., Kohn, K. W., and Pommier, Y. Induction of a common pathway of apoptosis by staurosporine. Exp. Cell Res., 211: 314-321, 1994.
-
(1994)
Exp. Cell Res.
, vol.211
, pp. 314-321
-
-
Bertrand, R.1
Solary, E.2
O'Connor, P.3
Kohn, K.W.4
Pommier, Y.5
-
33
-
-
0032531823
-
Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector
-
Krohn, A. J., Preis, E., and Prehn, J. H. Staurosporine-induced apoptosis of cultured rat hippocampal neurons involves caspase-1-like proteases as upstream initiators and increased production of superoxide as a main downstream effector. J. Neurosci., 18: 8186-8197, 1998.
-
(1998)
J. Neurosci.
, vol.18
, pp. 8186-8197
-
-
Krohn, A.J.1
Preis, E.2
Prehn, J.H.3
-
34
-
-
0032031529
-
Staurosporine-induced apoptosis in cardiomyocytes: A potential role of caspase-3
-
Yue, T. L., Wang, C., Romanic, A. M., Kikly, K., Keller, P., DeWolf, W. E., Jr., Hart, T. K., Thomas, H. C., Storer, B., Gu, J. L., Wang, X., and Feuerstein, G. Z. Staurosporine-induced apoptosis in cardiomyocytes: a potential role of caspase-3. J. Mol. Cell. Cardiol., 30: 495-507, 1998.
-
(1998)
J. Mol. Cell. Cardiol.
, vol.30
, pp. 495-507
-
-
Yue, T.L.1
Wang, C.2
Romanic, A.M.3
Kikly, K.4
Keller, P.5
DeWolf W.E., Jr.6
Hart, T.K.7
Thomas, H.C.8
Storer, B.9
Gu, J.L.10
Wang, X.11
Feuerstein, G.Z.12
-
35
-
-
0030873361
-
Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L)
-
Benito, A., Lerga, A., Silva, M., Leon, J., and Fernandez-Luna, J. L. Apoptosis of human myeloid leukemia cells induced by an inhibitor of protein phosphatases (okadaic acid) is prevented by Bcl-2 and Bcl-X(L). Leukemia (Baltimore), 11: 940-944, 1997.
-
(1997)
Leukemia (Baltimore)
, vol.11
, pp. 940-944
-
-
Benito, A.1
Lerga, A.2
Silva, M.3
Leon, J.4
Fernandez-Luna, J.L.5
-
36
-
-
0031945458
-
Cell cycle regulation and apoptosis
-
King, K. L., and Cidlowski, J. A. Cell cycle regulation and apoptosis. Annu. Rev. Physiol., 60: 601-617, 1998.
-
(1998)
Annu. Rev. Physiol.
, vol.60
, pp. 601-617
-
-
King, K.L.1
Cidlowski, J.A.2
-
37
-
-
0028972072
-
Transforming growth factor-β (TGF-β)-induced down-regulation of cyclin A expression requires a functional TGF-β receptor complex
-
Feng, X-H., Filvaroff, E. H., and Derynck, R. Transforming growth factor-β (TGF-β)-induced down-regulation of cyclin A expression requires a functional TGF-β receptor complex. J. Biol. Chem., 270: 24237-24245, 1995.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 24237-24245
-
-
Feng, X.-H.1
Filvaroff, E.H.2
Derynck, R.3
-
38
-
-
0029460849
-
Transforming growth factor-βs in mammary tumorigenesis: Promoters or antipromoters?
-
Wakefield, L. M., Letterio, J. J., Geiser, A. G., Flanders, K. C., O'Shaughnessy, J., Roberts, A. B., and Sporn, M. B. Transforming growth factor-βs in mammary tumorigenesis: promoters or antipromoters? Prog. Clin. Biol. Res., 391: 133-148, 1995.
-
(1995)
Prog. Clin. Biol. Res.
, vol.391
, pp. 133-148
-
-
Wakefield, L.M.1
Letterio, J.J.2
Geiser, A.G.3
Flanders, K.C.4
O'Shaughnessy, J.5
Roberts, A.B.6
Sporn, M.B.7
-
39
-
-
0031303927
-
Transforming growth factor-β and cancer: A love-hate relationship?
-
Reiss, M. Transforming growth factor-β and cancer: a love-hate relationship? Oncol. Res., 9: 447-457, 1997.
-
(1997)
Oncol. Res.
, vol.9
, pp. 447-457
-
-
Reiss, M.1
-
40
-
-
0030183051
-
Tumor suppressor activity of the TGF-β pathway in human cancers
-
Markowitz, S. D., and Roberts, A. B. Tumor suppressor activity of the TGF-β pathway in human cancers. Cytokine Growth Factor Rev., 7: 93-102, 1996.
-
(1996)
Cytokine Growth Factor Rev.
, vol.7
, pp. 93-102
-
-
Markowitz, S.D.1
Roberts, A.B.2
-
41
-
-
0029991231
-
Reduced levels of transforming growth factor β receptor type II in human prostate cancer: An immunohistochemical study
-
Williams, R. H., Stapleton, A. M. F., Yang, G., Truong, L. D., Rogers, E., Timme, T. L., Wheeler, T. M., Scardino, P. T., and Thompson, T. C. Reduced levels of transforming growth factor β receptor type II in human prostate cancer: an immunohistochemical study. Clin. Cancer Res., 2: 635-640, 1996.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 635-640
-
-
Williams, R.H.1
Stapleton, A.M.F.2
Yang, G.3
Truong, L.D.4
Rogers, E.5
Timme, T.L.6
Wheeler, T.M.7
Scardino, P.T.8
Thompson, T.C.9
-
42
-
-
0029938791
-
A dominant inhibitory mutant of the type II transforming growth factor β receptor in the malignant progression of a cutaneous T-cell lymphoma
-
Knaus, P. I., Lindemann, D., DeCoteau, J. F., Perlman, R., Yankelev, H., Hille, M., Kadin, M. E., and Lodish, H. F. A dominant inhibitory mutant of the type II transforming growth factor β receptor in the malignant progression of a cutaneous T-cell lymphoma. Mol. Cell. Biol., 16: 3480-3489, 1996.
-
(1996)
Mol. Cell. Biol.
, vol.16
, pp. 3480-3489
-
-
Knaus, P.I.1
Lindemann, D.2
DeCoteau, J.F.3
Perlman, R.4
Yankelev, H.5
Hille, M.6
Kadin, M.E.7
Lodish, H.F.8
-
43
-
-
0030048263
-
Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β in human prostate cancer cells
-
Kim, I. Y., Ahn, H. J., Zelner, D. J., Shaw, J. W., Sensibar, J. A., Kim, J. H., Kato, M., and Lee, C. Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β in human prostate cancer cells. Cancer Res., 56: 44-48, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 44-48
-
-
Kim, I.Y.1
Ahn, H.J.2
Zelner, D.J.3
Shaw, J.W.4
Sensibar, J.A.5
Kim, J.H.6
Kato, M.7
Lee, C.8
-
44
-
-
0031982581
-
A novel ets-related transcription factor, ERT/ESX/ESE-1, regulates expression of the transforming growth factor-β type II receptor
-
Choi, S. G., Yi, Y., Kim, Y. S., Kato, M., Chang, J., Chung, H. W., Hahm, K. B., Yang, H. K., Rhee, H. H., Bang, Y. J., and Kim, S. J. A novel ets-related transcription factor, ERT/ESX/ESE-1, regulates expression of the transforming growth factor-β type II receptor. J. Biol. Chem., 273: 110-117, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 110-117
-
-
Choi, S.G.1
Yi, Y.2
Kim, Y.S.3
Kato, M.4
Chang, J.5
Chung, H.W.6
Hahm, K.B.7
Yang, H.K.8
Rhee, H.H.9
Bang, Y.J.10
Kim, S.J.11
-
45
-
-
0032568956
-
Induction of transforming growth factor-β receptor type II expression in estrogen receptor-positive breast cancer cells through SP1 activation by 5-aza-2′-deoxycytidine
-
Ammanamanchi, S., Kim, S. J., Sun, L. Z., and Brattain, M. G. Induction of transforming growth factor-β receptor type II expression in estrogen receptor-positive breast cancer cells through SP1 activation by 5-aza-2′-deoxycytidine. J. Biol. Chem., 273: 16527-16534, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16527-16534
-
-
Ammanamanchi, S.1
Kim, S.J.2
Sun, L.Z.3
Brattain, M.G.4
-
46
-
-
0030460085
-
Cancer gets Mad: DPC4 and other TGF-β pathway genes in human cancer
-
Moskaluk, C. A., and Kern, S. E. Cancer gets Mad: DPC4 and other TGF-β pathway genes in human cancer. Biochim. Biophys. Acta, 1288: M31-M33, 1996.
-
(1996)
Biochim. Biophys. Acta
, vol.1288
-
-
Moskaluk, C.A.1
Kern, S.E.2
-
47
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGF-β-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert, K., Scherer, S. W., Ozcelik, H., Pirone, R., Hoodless, P., Kim, H., Tsui, L. C., Bapat, B., Gallinger, S., Andrulis, I. L., Thomsen, G. H., Wrana, J. L., and Attisano, L. MADR2 maps to 18q21 and encodes a TGF-β-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell, 86: 543-552, 1996.
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
Pirone, R.4
Hoodless, P.5
Kim, H.6
Tsui, L.C.7
Bapat, B.8
Gallinger, S.9
Andrulis, I.L.10
Thomsen, G.H.11
Wrana, J.L.12
Attisano, L.13
-
48
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn, S. A., Schutte, M., Hoque, A. T., Moskaluk, C. A., da Costa, L. T., Rozenblum, E., Weinstein, C. L., Fischer, A., Yeo, C. J., Hruban, R. H., and Kern, S. E. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science (Washington DC), 271: 350-353, 1996.
-
(1996)
Science (Washington DC)
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
49
-
-
9344223357
-
DPC4 gene in various tumor types
-
Schutte, M., Hruban, R. H., Hedrick, L., Cho, K. R., Nadasdy, G. M., Weinstein, C. L., Bova, G. S., Isaacs, W. B., Cairns, P., Nawroz, H., Sidransky, D., Casero, R. A., Jr., Meltzer, P. S., Hahn, S. A., and Kern, S. E. DPC4 gene in various tumor types. Cancer Res., 56: 2527-2530, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 2527-2530
-
-
Schutte, M.1
Hruban, R.H.2
Hedrick, L.3
Cho, K.R.4
Nadasdy, G.M.5
Weinstein, C.L.6
Bova, G.S.7
Isaacs, W.B.8
Cairns, P.9
Nawroz, H.10
Sidransky, D.11
Casero R.A., Jr.12
Meltzer, P.S.13
Hahn, S.A.14
Kern, S.E.15
-
50
-
-
0029933642
-
Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers
-
Nagatake, M., Takagi, Y., Osada, H., Uchida, K., Mitsudomi, T., Saji, S., Shimokata, K., Takahashi, T., and Takahashi, T. Somatic in vivo alterations of the DPC4 gene at 18q21 in human lung cancers. Cancer Res., 56: 2718-2720, 1996.
-
(1996)
Cancer Res.
, vol.56
, pp. 2718-2720
-
-
Nagatake, M.1
Takagi, Y.2
Osada, H.3
Uchida, K.4
Mitsudomi, T.5
Saji, S.6
Shimokata, K.7
Takahashi, T.8
Takahashi, T.9
-
51
-
-
0021879645
-
Hereditary cancer, oncogenes, and antioncogenes
-
Knudson, A. G., Jr. Hereditary cancer, oncogenes, and antioncogenes. Cancer Res., 45: 1437-1443, 1985.
-
(1985)
Cancer Res.
, vol.45
, pp. 1437-1443
-
-
Knudson A.G., Jr.1
-
52
-
-
0027250810
-
Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities
-
Chen, R. H., Ebner, R., and Derynck, R. Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities. Science (Washington DC), 260: 1335-1338, 1993.
-
(1993)
Science (Washington DC)
, vol.260
, pp. 1335-1338
-
-
Chen, R.H.1
Ebner, R.2
Derynck, R.3
-
53
-
-
0028859484
-
Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β1
-
McCaffrey, T. A., Consigli, S., Du, B., Falcone, D. J., Sanborn, T. A., Spokojny, A. M., and Bush, H. L., Jr. Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β1. J. Clin. Investig., 96: 2667-2675, 1995.
-
(1995)
J. Clin. Investig.
, vol.96
, pp. 2667-2675
-
-
McCaffrey, T.A.1
Consigli, S.2
Du, B.3
Falcone, D.J.4
Sanborn, T.A.5
Spokojny, A.M.6
Bush H.L., Jr.7
-
54
-
-
0029980518
-
Modulation of transforming growth factor-β receptor levels on microvascular endothelial cells during in vitro angiogenesis
-
Sankar, S., Mahooti-Brooks, N., Bensen, L., McCarthy, T. L., Centrella, M., and Madri, J. A. Modulation of transforming growth factor-β receptor levels on microvascular endothelial cells during in vitro angiogenesis. J. Clin. Investig., 97: 1436-1446, 1996.
-
(1996)
J. Clin. Investig.
, vol.97
, pp. 1436-1446
-
-
Sankar, S.1
Mahooti-Brooks, N.2
Bensen, L.3
McCarthy, T.L.4
Centrella, M.5
Madri, J.A.6
-
55
-
-
0029959774
-
Phosphorylation of Ser165 in TGF-β type I receptor modulates TGF-β1-induced cellular responses
-
Souchelnytskyi, S., ten Dijke, P., Miyazono, K., and Heldin, C. H. Phosphorylation of Ser165 in TGF-β type I receptor modulates TGF-β1-induced cellular responses. EMBO J., 15: 6231-6240, 1996.
-
(1996)
EMBO J.
, vol.15
, pp. 6231-6240
-
-
Souchelnytskyi, S.1
Ten Dijke, P.2
Miyazono, K.3
Heldin, C.H.4
-
56
-
-
0033214970
-
Loss of responsiveness to transforming growth factor β induces malignant transformation of nontumorigenic rat prostate epithelial cells
-
Tang, B., de Castro, K., Barnes, H. E., Parks, W. T., Stewart, L., Böttinger, E. P., Danielpour, D., and Wakefield, L. M. Loss of responsiveness to transforming growth factor β induces malignant transformation of nontumorigenic rat prostate epithelial cells. Cancer Res., 59: 4834-4842, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 4834-4842
-
-
Tang, B.1
De Castro, K.2
Barnes, H.E.3
Parks, W.T.4
Stewart, L.5
Böttinger, E.P.6
Danielpour, D.7
Wakefield, L.M.8
-
57
-
-
0032575752
-
Mitochondria and apoptosis
-
Green, D. R., and Reed, J. C. Mitochondria and apoptosis. Science (Washington DC), 281, 1309-1312, 1998.
-
(1998)
Science (Washington DC)
, vol.281
, pp. 1309-1312
-
-
Green, D.R.1
Reed, J.C.2
-
58
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross, A., McDonnell, J. M., and Korsmeyer, S. J. BCL-2 family members and the mitochondria in apoptosis. Genes Dev., 13: 1899-1911, 1999.
-
(1999)
Genes Dev.
, vol.13
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
59
-
-
0032504581
-
Bcl-2 family proteins and mitochondria
-
Reed, J. C., Jurgensmeier, J. M., and Matsuyama, S. Bcl-2 family proteins and mitochondria. Biochim. Biophys. Acta, 1366: 127-137, 1998.
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 127-137
-
-
Reed, J.C.1
Jurgensmeier, J.M.2
Matsuyama, S.3
-
60
-
-
0032580361
-
Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins
-
Zamzami, N., Brenner, C., Marzo, I., Susin, S. A., and Kroemer, G. Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins. Oncogene, 16: 2265-2282, 1998.
-
(1998)
Oncogene
, vol.16
, pp. 2265-2282
-
-
Zamzami, N.1
Brenner, C.2
Marzo, I.3
Susin, S.A.4
Kroemer, G.5
-
61
-
-
0008824942
-
The domains of death: Evolution of the apoptotic machinery
-
Aravind, L., Dixit, V. M., and Koonin, E. V. The domains of death: evolution of the apoptotic machinery. Trends Biochem. Sci., 24: 47-53, 1999.
-
(1999)
Trends Biochem. Sci.
, vol.24
, pp. 47-53
-
-
Aravind, L.1
Dixit, V.M.2
Koonin, E.V.3
-
62
-
-
0025048136
-
The P-loop-a common motif in ATP- and GTP-binding proteins
-
Saraste, M., Sibbald, P. R., and Wittinghofer A. The P-loop-a common motif in ATP- and GTP-binding proteins. Trends Biochem. Sci., 11: 430-434, 1990.
-
(1990)
Trends Biochem. Sci.
, vol.11
, pp. 430-434
-
-
Saraste, M.1
Sibbald, P.R.2
Wittinghofer, A.3
-
63
-
-
0032504224
-
The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease
-
Chaudhary, D., O'Rourke, K., Chinnaiyan, A. M., and Dixit, V. M. The death inhibitory molecules CED-9 and CED-4L use a common mechanism to inhibit the CED-3 death protease. J. Biol. Chem., 273: 17708-17712, 1998.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 17708-17712
-
-
Chaudhary, D.1
O'Rourke, K.2
Chinnaiyan, A.M.3
Dixit, V.M.4
-
64
-
-
0344348821
-
Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis
-
Hu, Y., Benedict, M. A., Ding., L., and Núñez, G. Role of cytochrome c and dATP/ATP hydrolysis in Apaf-1-mediated caspase-9 activation and apoptosis. EMBO J., 18: 3586-3595, 1999.
-
(1999)
EMBO J.
, vol.18
, pp. 3586-3595
-
-
Hu, Y.1
Benedict, M.A.2
Ding, L.3
Núñez, G.4
-
65
-
-
0024421852
-
Expression of transforming growth factor-β in the rat ventral prostate during castration-induced programmed cell death
-
Kyprianou, N., and Isaacs, J. T. Expression of transforming growth factor-β in the rat ventral prostate during castration-induced programmed cell death. Mol. Endocrinol., 3: 1515-1522, 1989.
-
(1989)
Mol. Endocrinol.
, vol.3
, pp. 1515-1522
-
-
Kyprianou, N.1
Isaacs, J.T.2
-
66
-
-
0033559189
-
Restoration of transforming growth factor β signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1-mediated apoptosis
-
Guo, Y., and Kyprianou, N. Restoration of transforming growth factor β signaling pathway in human prostate cancer cells suppresses tumorigenicity via induction of caspase-1-mediated apoptosis. Cancer Res., 59: 1366-1371, 1999.
-
(1999)
Cancer Res.
, vol.59
, pp. 1366-1371
-
-
Guo, Y.1
Kyprianou, N.2
-
67
-
-
0030972216
-
Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-β1 on programmed cell death through a p53- and IGF-independent mechanism
-
Rajah, R., Valentinis, B., and Cohen, P. Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-β1 on programmed cell death through a p53- and IGF-independent mechanism. J. Biol. Chem., 272: 12181-12188. 1997.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 12181-12188
-
-
Rajah, R.1
Valentinis, B.2
Cohen, P.3
-
68
-
-
0031031450
-
Fenretinide: Induction of apoptosis and endogenous transforming growth factor β in PC-3 prostate cancer cells
-
Roberson, K. M., Penland, S. N., Padilla, G. M., Selvan, R. S., Kim, C. S., Fine, R. L., and Robertson, C. N. Fenretinide: induction of apoptosis and endogenous transforming growth factor β in PC-3 prostate cancer cells. Cell Growth Differ., 8: 101-111, 1997.
-
(1997)
Cell Growth Differ.
, vol.8
, pp. 101-111
-
-
Roberson, K.M.1
Penland, S.N.2
Padilla, G.M.3
Selvan, R.S.4
Kim, C.S.5
Fine, R.L.6
Robertson, C.N.7
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