Targeted deletion of Smad4 shows it is required for transforming growth factor β and activin signaling in colorectal cancer cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 5, 1998, Pages 2412-2416

  Zhou, Shibin ^a,b   Buckhaults, Phillip ^b   Zawel, Leigh ^b   Bunz, Fred ^a,b   Riggins, Greg ^b   Dai, Jia Le ^b,c   Kern, Scott E ^b,c   Kinzler, Kenneth W ^b   Vogelstein, Bert ^a,b,c  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN; TRANSFORMING GROWTH FACTOR BETA;

CARCINOGENESIS; CELL GROWTH; CELL PROLIFERATION; CLONAL ANERGY; COLON CANCER; CONFERENCE PAPER; GENE DELETION; GENE REPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR GENE;

EID: 0032478143     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.5.2412     Document Type: Article

References (56)

1. Hahn, S. A., Schutte, M., Hoque, A. T. M. S., Moskaluk, C. A., Dacosta, L. T., et al. (1996) Science 271, 350-353.
2. Thiagalingam, S., Lengaver, C., Leach, F. S., Schutte, M., Hahn, S. A., et al. (1996) Nat. Genet. 13, 343-346.
3. Sekelsky, J. J., Newfeld, S. J., Raftery, L. A., Chartoff, E. H. & Gelbart, W. M. (1995) Genetics 139, 1347-1358.
4. Fynan, T. M. & Reiss, M. (1993) Crit. Rev. Oncog. 4, 493-540.
5. Graff, J. M., Bansal, A. & Melton, D. A. (1996) Cell 85, 479-487.
6. Thomsen, G. H. (1996) Development (Cambridge, U.K.) 122, 2359-2366.
7. Riggins, G. J., Thiagalingam, S., Rozenblum, E., Weinstein, C. L., Kern, S. E., Hamilton, S. R., Willson, J. K., Markowitz, S. D., Kinzler, K. W. & Vogelstein, B. (1996) Nat. Genet. 13, 347-349.
8. Zhang, Y., Feng, X., We, R. & Derynck, R. (1996) Nature (London) 383, 168-172.
9. Liu, F. (1996) Nature (London) 381, 620-623.
10. Hoodless, P. (1996) Cell 85, 489-500.
11. Baker, J. C. & Harland, R. M. (1996) Genes Dev. 10, 1880-1889.
12. Eppert, K., Scherer, S. W., Ozcelik, H., Pirone, R., Hoodless, P., et al. (1996) Cell 86, 543-552.
13. Lechleider, R. J., de Caestecker, M. P., Dehejia, A., Polymeropoulos, M. H. & Roberts, A. B. (1996) J. Biol. Chem. 271, 17617-17620.
14. Yingling, J., Das, P., Savage, S., Zhang, M., Padgett, R. & Wang, X. (1996) Proc. Natl. Acad. Sci. USA 93, 8940-8944.
15. Derynck, R., Gelbert, W. M., Harland, R. M., Heldin, C. H., Kern, S. E., et al. (1996) Cell 87, 173.
16. Macias-Silva, M., Abdollah, S., Hoodless, P. A., Pirone, R., Attisano, L. & Wrana, J. L. (1996) Cell 87, 1215-1224.
17. Imamura, T., Takase, M., Nishihara, A., Oeda, E., Hanai, J., Kawabata, M. & Miyazono, K. (1997) Nature (London) 389, 622-626.
18. Nakao, A., Afrakhte, M., Moren, A., Nakayama, T., Christian, J. L., Heuchel, R., Itoh, S., Kawabata, M., Heldin, N. E., Heldin, C. H. & ten Dijke, P. (1997) Nature (London) 389, 631-635.
19. Hayashi, H., Abdollah, S., Qiu, Y., Cai, J., Xu, Y. Y., Grinnell, B. W., Richardson, M. A., Topper, J. N., Gimbrone, M. A., Jr., Wrana, J. L. & Falb, D. (1997) Cell 89, 1165-1173.
20. Pattersonn, G. I., Koweek, A., Wong, A., Liu, Y. & Ruvkun, G. (1997) Genes Dev. 11, 2679-2690.
21. Kim, J., Johnson, K., Chen, H. J., Carroll, S. & Laughon, A. (1997) Nature (London) 388, 304-308.
22. Lagna, G., Hata, A., Hemmati-Brivanlou, A. & Massague, J. (1996) Nature (London) 383, 832-836.
23. Nakao, A., Imamura, T., Souchelnytskyi, S., Kawabata, M., Ishisaki, A., Oeda, E., Tamaki, K., Hanai, J., Heldin, C. H., Miyazono, K. & ten Dijke, P. (1997) EMBO J. 16, 5353-5362.
24. Chen, X., Rubock, M. J. & Whitman, M. (1996) Nature (London) 383, 691-696.
25. Chen, X., Weisberg, E., Fridmacher, V., Watanabe, M., Naco, G. & Whitman, M. (1997) Nature (London) 389, 85-89.
26. Wu, R. Y., Zhang, Y., Feng, X. H. & Derynck, R. (1997) Mol. Cell. Biol. 17, 2521-2528.
27. Kingsley, D. M. (1994) Genes Dev. 8, 133-146.
28. Roberts, A. B. & Sporn, M. B. (1993) Growth Factors 8, 1-9.
29. Satterwhite, D. J. & Moses, H. L. (1994) Invasion Metastasis 14, 309-318.
30. Hsu, S., Huang, F., Hafez, M., Winawer, S. & Friedman, E. (1994) Cell Growth Differ. 5, 267-275.
31. Huang, F., Newman, E., Theodorescu, D., Kerbel, R. S. & Friedman, E. (1995) Cell Growth Differ. 6, 1635-1642.
32. Hata, A., Lo, R. S., Wotton, D., Lagna, G. & Massague, J. (1997) Nature (London) 388, 82-87.
33. de Caestecker, M. P., Hemmati, P., Larisch-Bloch, S., Ajmera, R., Roberts, A. B. & Lechleider, R. J. (1997) J. Biol. Chem 272, 13690-13696.
34. de Winter, J. P., Roelen, B. A., ten Dijke, P., van der Burg, B. & van den Eijnden-van Raaij, A. J. (1997) Oncogene 14, 1891-1899.
35. Waldman, T., Kinzler, K. W. & Vogelstein, B. (1995) Cancer Res. 55, 5187-5190.
36. Hahn, S. A., Hoque, A. T., Moskaluk, C. A., da Costa, L. T., Schutte, M., Rozenblum, E., Seymour, A. B., Weinstein, C L., Yeo, C. J., Hruban, R. H. & Kern, S. E. (1996) Cancer Res. Res. 56, 490-494.
37. Larsen, R. D., Rajan, V. P., Ruff, M. M., Kukowska-Latallo, J., Cummings, R. D. & Lowe, J. B. (1989) Proc. Natl. Acad. Sci. USA 86, 8227-8231.
38. Wrana, J. L., Attisano, L., Carcamo, J., Zentella, A., Doody, J., Laiho, M., Wang, X. F. & Massague, J. (1992) Cell 71, 1003-1014.
39. Parsons, R., Myeroff, L. L., Liu, B., Willson, J. K., Markowitz, S. D., Kinzler, K. W. & Vogelstein, B. (1995) Cancer Res. 55, 5548-5550.
40. Keeton, M. R., Curriden, S. A., van Zonneveld, A. J. & Loskutoff, D. J. (1991) J. Biol. Chem. 266, 23048-23052.
41. Coffey, R. J., Jr., Goustin, A. S., Soderquist, A. M., Shipley, G. D., Wolfshohl, J., Carpenter, G. & Moses, H. L. (1987) Cancer Res. 47, 4590-4594.
42. Wang, J., Sun, L., Myeroff, L., Wang, X., Gentry, L. E., et al. (1995) J. Biol. Chem. 270, 22044-22049.
43. Wieser, R., Wrana, J. L. & Massague, J. (1995) EMBO J. 14, 2199-2208.
44. Attisano, L., Wrana, J. L., Montalvo, E. & Massague, J. (1996) Mol. Cell. Biol. 16, 1066-1073.
45. Hoosein, N. M., Brattain, D. E., McKnight, M. K., Levine, A. E. & Brattain, M. G. (1987) Cancer Res. 47, 2950-2954.
46. Hoosein, N. M., McKnight, M. K., Levine, A. E., Mulder, K. M., Childress, K. E., Brattain, D. E. & Brattain, M. G. (1989) Exp. Cell Res. 181, 442-453.
47. Mulder, K. M., Zhong, Q., Choi, H. G., Humphrey, L. E. & Brattain, M. G. (1990) Cancer Res. 50, 7581-7586.
48. Grau, A. M., Zhang, L., Wang, W., Ruan, S., Evans, D. B., Abbruzzese, J. L., Zhang, W. & Chiao, P. J. (1997) Cancer Res. 57, 3929-3934.
49. Chang, J., Park, K., Bang, Y. J., Kim, W. S., Kim, D. & Kim, S. J. (1997) Cancer Res. 57, 2856-2859.
50. Hafez, M. M., Infante, D., Winawer, S. & Friedman, E. (1990) Cell Growth Differ. 1, 617-626.
51. Suardet, L., Gaide, A. C., Calmes, J. M., Sordat, B., Givel, J. C., Eliason, J. F. & Odartchenko, N. (1992) Cancer Res. 52, 3705-3712.
52. Wu, S. P., Sun, L. Z., Willson, J. K., Humphrey, L., Kerbel, R. & Brattain, M. G. (1993) Cell Growth Differ. 4, 115-123.
53. Levine, A. E. & Lewis, L. R. (1993) Cancer Lett. 68, 33-41.
54. Wang, D., Zhou, G. H., Birkenmeier, T. M., Gong, J., Sun, L. & Brattain, M. G. (1995) J. Biol. Chem. 270, 14154-14159.
55. Markowitz, S., Wang, J., Myeroff, L., Parsons, R., Sun, L., et al. (1995) Science 268, 1336-1338.
56. Riggins, G. J., Kinzler, K. W., Vogelstein, B. & Thiagalingam, S. (1997) Cancer Res. 57, 2578-2580.