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Volumn 59, Issue 19, 1999, Pages 4834-4842

Loss of responsiveness to transforming growth factor β induces malignant transformation of nontumorigenic rat prostate epithelial cells

Author keywords

[No Author keywords available]

Indexed keywords

FIBRONECTIN; RNA; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR;

EID: 0033214970     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (75)

References (55)
  • 2
    • 0031685620 scopus 로고    scopus 로고
    • TGF-β signal transduction
    • Massagué. J. TGF-β signal transduction. Annu. Rev. Biochem., 67: 753-791, 1998.
    • (1998) Annu. Rev. Biochem. , vol.67 , pp. 753-791
    • Massagué, J.1
  • 4
    • 0025222517 scopus 로고
    • The transforming growth factor-β family
    • Massagué, J. The transforming growth factor-β family. Annu. Rev. Cell Biol., 6: 597-641, 1990.
    • (1990) Annu. Rev. Cell Biol. , vol.6 , pp. 597-641
    • Massagué, J.1
  • 5
    • 0030604542 scopus 로고    scopus 로고
    • TGFβ signaling: Receptors, transducers, and mad proteins
    • Massagué, J. TGFβ signaling: receptors, transducers, and Mad proteins. Cell, 85: 947-950, 1996.
    • (1996) Cell , vol.85 , pp. 947-950
    • Massagué, J.1
  • 6
    • 0031438047 scopus 로고    scopus 로고
    • TGF-β signalling from cell membrane to nucleus through SMAD proteins
    • Lond.
    • Heldin, C. H., Miyazono, K., and ten Dijke, P. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature (Lond.), 390: 465-471, 1997.
    • (1997) Nature , vol.390 , pp. 465-471
    • Heldin, C.H.1    Miyazono, K.2    Dijke P. X3
  • 7
    • 0030183051 scopus 로고    scopus 로고
    • Tumor suppressor activity of the TGF-β pathway in human cancers
    • Markowitz, S. D., and Roberts, A. B. Tumor suppressor activity of the TGF-β pathway in human cancers. Cytokine Growth Factor Rev., 7: 93-102, 1996.
    • (1996) Cytokine Growth Factor Rev. , vol.7 , pp. 93-102
    • Markowitz, S.D.1    Roberts, A.B.2
  • 8
    • 0344625381 scopus 로고    scopus 로고
    • TGF-β signaling and cancer: Structural and functional consequences of mutations in smads
    • Hata, A., Shi, Y., and Massagué, J. TGF-β signaling and cancer: structural and functional consequences of mutations in smads. Mol. Med. Today, 4: 257-262, 1998.
    • (1998) Mol. Med. Today , vol.4 , pp. 257-262
    • Hata, A.1    Shi, Y.2    Massagué, J.3
  • 9
    • 0031303927 scopus 로고    scopus 로고
    • Transforming growth factor-β and cancer: A love-hate relationship?
    • Reiss, M. Transforming growth factor-β and cancer: a love-hate relationship? Oncol. Res., 9: 447-457, 1997.
    • (1997) Oncol. Res. , vol.9 , pp. 447-457
    • Reiss, M.1
  • 10
    • 0031441041 scopus 로고    scopus 로고
    • Transgenic mice overexpressing a dominant-negative mutant type 11 transforming growth factor β receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene
    • Böttinger, E. P., Jakubczak, J. L., Haines, D. C., Bagnall, K., and Wakefield, L. M. Transgenic mice overexpressing a dominant-negative mutant type 11 transforming growth factor β receptor show enhanced tumorigenesis in the mammary gland and lung in response to the carcinogen 7,12-dimethylbenz-[a]-anthracene. Cancer Res., 57: 5564-5570, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 5564-5570
    • Böttinger, E.P.1    Jakubczak, J.L.2    Haines, D.C.3    Bagnall, K.4    Wakefield, L.M.5
  • 11
    • 0032500010 scopus 로고    scopus 로고
    • Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development
    • Amendt, C., Schirmacher, P., Weber, H., and Blessing, M. Expression of a dominant negative type II TGF-β receptor in mouse skin results in an increase in carcinoma incidence and an acceleration of carcinoma development. Oncogene, 17: 25-34, 1998.
    • (1998) Oncogene , vol.17 , pp. 25-34
    • Amendt, C.1    Schirmacher, P.2    Weber, H.3    Blessing, M.4
  • 13
    • 0030774892 scopus 로고    scopus 로고
    • Expression of transforming growth factor β type III receptor suppresses tumorigenicity of human breast cancer MDA-MB-231 cells
    • Sun, L., and Chen, C. Expression of transforming growth factor β type III receptor suppresses tumorigenicity of human breast cancer MDA-MB-231 cells. J. Biol. Chem., 272: 25367-25372, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 25367-25372
    • Sun, L.1    Chen, C.2
  • 14
    • 0031990782 scopus 로고    scopus 로고
    • Overexpression of transforming growth factor (TGF) β1 type II receptor restores TGF-β1 sensitivity and signaling in human prostate cancer cells
    • Guo, Y., and Kyprianou, N. Overexpression of transforming growth factor (TGF) β1 type II receptor restores TGF-β1 sensitivity and signaling in human prostate cancer cells. Cell Growth Differ., 9: 185-193, 1998.
    • (1998) Cell Growth Differ. , vol.9 , pp. 185-193
    • Guo, Y.1    Kyprianou, N.2
  • 15
    • 0032544448 scopus 로고    scopus 로고
    • Smad3 mutant mice develop melastatic colorectal cancer
    • Zhu, Y., Richardson, J. A., Parada, L. F., and Graff, J. M. Smad3 mutant mice develop melastatic colorectal cancer. Cell, 94: 703-714, 1998.
    • (1998) Cell , vol.94 , pp. 703-714
    • Zhu, Y.1    Richardson, J.A.2    Parada, L.F.3    Graff, J.M.4
  • 16
    • 0032489508 scopus 로고    scopus 로고
    • Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes
    • Takaku, K., Oshima, M., Miyoshi, H., Matsui, M., Seldin, M. F., and Taketo, M. M. Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes. Cell, 92: 645-656, 1998.
    • (1998) Cell , vol.92 , pp. 645-656
    • Takaku, K.1    Oshima, M.2    Miyoshi, H.3    Matsui, M.4    Seldin, M.F.5    Taketo, M.M.6
  • 19
    • 0023740063 scopus 로고
    • Identification of a cellular receptor for transforming growth factor-β in rat ventral prostate and its negative regulation by androgens
    • Kyprianou, N., and Isaacs, J. T. Identification of a cellular receptor for transforming growth factor-β in rat ventral prostate and its negative regulation by androgens. Endocrinology, 123: 2124-2131, 1988.
    • (1988) Endocrinology , vol.123 , pp. 2124-2131
    • Kyprianou, N.1    Isaacs, J.T.2
  • 20
    • 0028916801 scopus 로고
    • Mesenchymal-epithelial interactions and transforming growth factor-β1 expression during normal and abnormal prostatic growth
    • Timme, T. L., Truong, L. D., Slawin, K. M., Kadmon, D., Park, S. H., and Thompson, T. C. Mesenchymal-epithelial interactions and transforming growth factor-β1 expression during normal and abnormal prostatic growth. Microsc. Res. Tech., 30: 333-341, 1995.
    • (1995) Microsc. Res. Tech. , vol.30 , pp. 333-341
    • Timme, T.L.1    Truong, L.D.2    Slawin, K.M.3    Kadmon, D.4    Park, S.H.5    Thompson, T.C.6
  • 21
    • 0030043537 scopus 로고    scopus 로고
    • Expression and localization of transforming growth factor-β receptors type I and type II in the rat ventral prostate during regression
    • Kim, I. Y., Ahn, H. J., Zelner, D. J., Park, L., Sensibar, J. A., and Lee, C. Expression and localization of transforming growth factor-β receptors type I and type II in the rat ventral prostate during regression. Mol. Endocrinol., 10: 107-115, 1996.
    • (1996) Mol. Endocrinol. , vol.10 , pp. 107-115
    • Kim, I.Y.1    Ahn, H.J.2    Zelner, D.J.3    Park, L.4    Sensibar, J.A.5    Lee, C.6
  • 22
    • 0025650608 scopus 로고
    • Effect of transforming growth factor-β1 on proliferation and death of rat prostatic cells
    • Martikainen, P., Kyprianou, N., and Isaacs, J. T. Effect of transforming growth factor-β1 on proliferation and death of rat prostatic cells. Endocrinology, 127: 2963-2968, 1990.
    • (1990) Endocrinology , vol.127 , pp. 2963-2968
    • Martikainen, P.1    Kyprianou, N.2    Isaacs, J.T.3
  • 23
    • 0028359232 scopus 로고
    • Development and characterization of nontumorigenic and tumorigenic epithelial cell lines from rat dorsal-lateral prostate
    • Danielpour, D., Kadomatsu, K., Anzano, M. A., Smith, J. M., and Sporn, M. B. Development and characterization of nontumorigenic and tumorigenic epithelial cell lines from rat dorsal-lateral prostate. Cancer Res., 54: 3413-3421, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3413-3421
    • Danielpour, D.1    Kadomatsu, K.2    Anzano, M.A.3    Smith, J.M.4    Sporn, M.B.5
  • 24
    • 0029806099 scopus 로고    scopus 로고
    • Regulation of apoptosis induced by transforming growth factor-β1 in nontumorigenic rat prostatic epithelial cell lines
    • Hsing, A. Y., Kadomatsu, K., Bonham, M. J., and Danielpour, D. Regulation of apoptosis induced by transforming growth factor-β1 in nontumorigenic rat prostatic epithelial cell lines. Cancer Res., 56: 5146-5149, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 5146-5149
    • Hsing, A.Y.1    Kadomatsu, K.2    Bonham, M.J.3    Danielpour, D.4
  • 25
    • 0028971602 scopus 로고
    • Transforming growth factor-β1: Comparative immuno-histochemical localization in human primary and metastatic prostate cancer
    • Eastham, J. A., Truong, L. D., Rogers, E., Kattan, M., Flanders, K. C., Scardino, P. T., and Thompson, T. C. Transforming growth factor-β1: comparative immuno-histochemical localization in human primary and metastatic prostate cancer. Lab. Investig.. 73: 628-635, 1995.
    • (1995) Lab. Investig. , vol.73 , pp. 628-635
    • Eastham, J.A.1    Truong, L.D.2    Rogers, E.3    Kattan, M.4    Flanders, K.C.5    Scardino, P.T.6    Thompson, T.C.7
  • 27
    • 0031776562 scopus 로고    scopus 로고
    • Loss of expression of transforming growth factor-β receptors is associated with poor prognosis in prostate cancer patients
    • Kim, I. Y., Ahn, H. J., Lang, S., Oefelein, M. G., Oyasu, R., Kozlowski, J. M., and Lee, C. Loss of expression of transforming growth factor-β receptors is associated with poor prognosis in prostate cancer patients. Clin. Cancer Res., 4: 1625-1630, 1998.
    • (1998) Clin. Cancer Res. , vol.4 , pp. 1625-1630
    • Kim, I.Y.1    Ahn, H.J.2    Lang, S.3    Oefelein, M.G.4    Oyasu, R.5    Kozlowski, J.M.6    Lee, C.7
  • 28
    • 0030048263 scopus 로고    scopus 로고
    • Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β 1 in human prostate cancer cells
    • Kim, I. Y., Ahn, H. J., Zelner, D. J., Shaw, J. W., Sensibar, J. A., Kim, J. H., Kato, M., and Lee, C. Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β 1 in human prostate cancer cells. Cancer Res., 56: 44-48, 1996.
    • (1996) Cancer Res. , vol.56 , pp. 44-48
    • Kim, I.Y.1    Ahn, H.J.2    Zelner, D.J.3    Shaw, J.W.4    Sensibar, J.A.5    Kim, J.H.6    Kato, M.7    Lee, C.8
  • 29
    • 0028902318 scopus 로고
    • Elevated plasma levels of TGF-β 1 in patients with invasive cancer
    • Ivanovic, V., Melman, A., Davis-Joseph, B., Valcic, M., and Geliebter, J. Elevated plasma levels of TGF-β 1 in patients with invasive cancer. Nat. Med., 1: 282-284, 1995.
    • (1995) Nat. Med. , vol.1 , pp. 282-284
    • Ivanovic, V.1    Melman, A.2    Davis-Joseph, B.3    Valcic, M.4    Geliebter, J.5
  • 30
    • 0026600577 scopus 로고
    • Transforming growth factor-β1 overproduction in prostate cancer: Effects on growth in vivo and in vitro
    • Steiner, M. S., and Barrack, E. R. Transforming growth factor-β1 overproduction in prostate cancer: effects on growth in vivo and in vitro, Mol. Endocrinol., 6: 15-25, 1992.
    • (1992) Mol. Endocrinol. , vol.6 , pp. 15-25
    • Steiner, M.S.1    Barrack, E.R.2
  • 31
    • 0032991493 scopus 로고    scopus 로고
    • Transdifferentiation of NRP152 rat prostatic basal epithelial cells toward a luminal phenotype: Regulation by glucocorticoid, insulin-like growth factor-I and transforming growth factor-β
    • Danielpour, D. Transdifferentiation of NRP152 rat prostatic basal epithelial cells toward a luminal phenotype: regulation by glucocorticoid, insulin-like growth factor-I and transforming growth factor-β. J. Cell Sci., 112: 169-179, 1999.
    • (1999) J. Cell Sci. , vol.112 , pp. 169-179
    • Danielpour, D.1
  • 32
    • 0033136037 scopus 로고    scopus 로고
    • The rat epithelial cell line NRP-152 can differentate in vivo in response to its stromal environment
    • Hayward, S. W., Haughney, P. C., Lopes, E. S., Danielpour, D., and Cunha, G. R. The rat epithelial cell line NRP-152 can differentate in vivo in response to its stromal environment. Prostate, 39: 205-212, 1999.
    • (1999) Prostate , vol.39 , pp. 205-212
    • Hayward, S.W.1    Haughney, P.C.2    Lopes, E.S.3    Danielpour, D.4    Cunha, G.R.5
  • 34
    • 0030029703 scopus 로고    scopus 로고
    • Induction of transforming growth factor-β autocrine activity by all-trans-retinoic acid and 1α,25-dihydroxyvitamin D3 in NRP-152 rat prostatic epithelial cells
    • Danielpour, D. Induction of transforming growth factor-β autocrine activity by all-trans-retinoic acid and 1α,25-dihydroxyvitamin D3 in NRP-152 rat prostatic epithelial cells. J. Cell Physiol., 166: 231-239, 1996.
    • (1996) J. Cell Physiol. , vol.166 , pp. 231-239
    • Danielpour, D.1
  • 35
    • 0027236954 scopus 로고
    • Production of high-titer helper-free retroviruses by transient transfection
    • Pear, W. S., Nolan, G. P., Scott, M. L., and Baltimore, D. Production of high-titer helper-free retroviruses by transient transfection. Proc. Natl. Acad. Sci. USA, 90: 8392-8396, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 8392-8396
    • Pear, W.S.1    Nolan, G.P.2    Scott, M.L.3    Baltimore, D.4
  • 36
    • 2142773830 scopus 로고    scopus 로고
    • Improved purification and yields of RNA by RNeasy
    • Bonham, M. J., and Danielpour, D. Improved purification and yields of RNA by RNeasy. Biotechniques, 21: 57-60, 1996.
    • (1996) Biotechniques , vol.21 , pp. 57-60
    • Bonham, M.J.1    Danielpour, D.2
  • 39
    • 0024509262 scopus 로고
    • Immunodetection and quantitation of the two forms of transforming growth factor-β (TGF-β 1 and TGF-β 2) secreted by cells in culture
    • Danielpour, D., Dart, L. L., Flanders, K. C., Roberts, A. B., and Sporn, M. B. Immunodetection and quantitation of the two forms of transforming growth factor-β (TGF-β 1 and TGF-β 2) secreted by cells in culture. J. Cell Physiol., 138: 79-86, 1989.
    • (1989) J. Cell Physiol. , vol.138 , pp. 79-86
    • Danielpour, D.1    Dart, L.L.2    Flanders, K.C.3    Roberts, A.B.4    Sporn, M.B.5
  • 40
    • 0030716244 scopus 로고    scopus 로고
    • Growth regulation of human prostate cancer cells by bone morphogenetic protein-2
    • Ide, H., Yoshida, T., Matsumoto, N., Aoki, K., Osada, Y., Sugimura, T., and Terada, M. Growth regulation of human prostate cancer cells by bone morphogenetic protein-2. Cancer Res., 57: 5022-5027, 1997.
    • (1997) Cancer Res. , vol.57 , pp. 5022-5027
    • Ide, H.1    Yoshida, T.2    Matsumoto, N.3    Aoki, K.4    Osada, Y.5    Sugimura, T.6    Terada, M.7
  • 41
    • 0023654923 scopus 로고
    • Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-β
    • Ignotz, R. A., Endo, T., and Massagué, J. Regulation of fibronectin and type I collagen mRNA levels by transforming growth factor-β. J. Biol. Chem., 262: 6443-6446, 1987.
    • (1987) J. Biol. Chem. , vol.262 , pp. 6443-6446
    • Ignotz, R.A.1    Endo, T.2    Massagué, J.3
  • 42
    • 0027250810 scopus 로고
    • Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities
    • Washington DC
    • Chen, R. H., Ebner, R., and Derynck, R. Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-β activities. Science (Washington DC), 260: 1335-1338, 1993.
    • (1993) Science , vol.260 , pp. 1335-1338
    • Chen, R.H.1    Ebner, R.2    Derynck, R.3
  • 43
    • 0026785290 scopus 로고
    • Inhibition of growth by transforming growth factor-ß following fusion of two nonresponsive human carcinoma cell lines. Implication of the type II receptor in growth inhibitory responses
    • Geiser, A. G., Burmester, J. K., Webbink, R., Roberts, A. B., and Sporn, M. B. Inhibition of growth by transforming growth factor-ß following fusion of two nonresponsive human carcinoma cell lines. Implication of the type II receptor in growth inhibitory responses. J. Biol. Chem., 267: 2588-2593, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 2588-2593
    • Geiser, A.G.1    Burmester, J.K.2    Webbink, R.3    Roberts, A.B.4    Sporn, M.B.5
  • 44
    • 0029004419 scopus 로고
    • Modulation of transforming growth factor β1 effects on prostate cancer cell proliferation by growth factors and extracellular matrix
    • Morton, D. M., and Barrack, E. R. Modulation of transforming growth factor β1 effects on prostate cancer cell proliferation by growth factors and extracellular matrix. Cancer Res., 55: 2596-2602, 1995.
    • (1995) Cancer Res. , vol.55 , pp. 2596-2602
    • Morton, D.M.1    Barrack, E.R.2
  • 45
    • 0023946119 scopus 로고
    • Tumors as caricatures of the process of tissue renewal: Prospects for therapy by directing differentiation
    • Pierce, G. B., and Speers, W. C. Tumors as caricatures of the process of tissue renewal: prospects for therapy by directing differentiation. Cancer Res., 48: 1996-2004, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 1996-2004
    • Pierce, G.B.1    Speers, W.C.2
  • 46
    • 0032527902 scopus 로고    scopus 로고
    • Mutation of the type II transforming growth factor-β receptor is coincident with the transformation of human colon adenomas to malignant carcinomas
    • Grady, W. M., Rajput, A., Myeroff, L., Liu, D. F., Kwon, K., Willis, J., and Markowitz, S. Mutation of the type II transforming growth factor-β receptor is coincident with the transformation of human colon adenomas to malignant carcinomas. Cancer Res., 58: 3101-3104, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 3101-3104
    • Grady, W.M.1    Rajput, A.2    Myeroff, L.3    Liu, D.F.4    Kwon, K.5    Willis, J.6    Markowitz, S.7
  • 48
    • 0031686001 scopus 로고    scopus 로고
    • Transforming growth factor β blocks cystogenesis by MDCK epithelium in vitro by enhancing the paracellular flux: Implication of collagen V
    • Altieri, P., Zegarra, M. O., Galietta, L. J., Tarelli, L. T., Sessa, A., and Ghiggeri, G. M. Transforming growth factor β blocks cystogenesis by MDCK epithelium in vitro by enhancing the paracellular flux: implication of collagen V. J. Cell Physiol., 177: 214-223, 1998.
    • (1998) J. Cell Physiol. , vol.177 , pp. 214-223
    • Altieri, P.1    Zegarra, M.O.2    Galietta, L.J.3    Tarelli, L.T.4    Sessa, A.5    Ghiggeri, G.M.6
  • 49
    • 0032547895 scopus 로고    scopus 로고
    • TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis
    • Oft, M., Heider, K. H., and Beug, H. TGFβ signaling is necessary for carcinoma cell invasiveness and metastasis. Curr. Biol., 8: 1243-1252, 1998.
    • (1998) Curr. Biol. , vol.8 , pp. 1243-1252
    • Oft, M.1    Heider, K.H.2    Beug, H.3
  • 51
    • 0031817391 scopus 로고    scopus 로고
    • Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: Implications for tumor invasion
    • Portella, G., Cumming, S. A., Liddell, J., Cui, W., Ireland, H., Akhurst, R. J., and Balmain, A. Transforming growth factor β is essential for spindle cell conversion of mouse skin carcinoma in vivo: implications for tumor invasion. Cell Growth Differ., 9: 393-404, 1998.
    • (1998) Cell Growth Differ. , vol.9 , pp. 393-404
    • Portella, G.1    Cumming, S.A.2    Liddell, J.3    Cui, W.4    Ireland, H.5    Akhurst, R.J.6    Balmain, A.7
  • 53
    • 0029883757 scopus 로고    scopus 로고
    • Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern
    • Fajardo, L. F., Prionas, S. D., Kwan, H. H., Kowalski, J., and Allison, A. C. Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern. Lab. Investig., 74: 600-608, 1996.
    • (1996) Lab. Investig. , vol.74 , pp. 600-608
    • Fajardo, L.F.1    Prionas, S.D.2    Kwan, H.H.3    Kowalski, J.4    Allison, A.C.5
  • 54
    • 0028859484 scopus 로고
    • Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β1
    • McCaffrey, T. A., Consigli, S., Du, B., Falcone, D. J., Sanborn, T. A., Spokojny, A. M., and Bush, H. L., Jr. Decreased type II/type I TGF-β receptor ratio in cells derived from human atherosclerotic lesions. Conversion from an antiproliferative to profibrotic response to TGF-β1. J. Clin. Investig., 96: 2667-2675, 1995.
    • (1995) J. Clin. Investig. , vol.96 , pp. 2667-2675
    • McCaffrey, T.A.1    Consigli, S.2    Du, B.3    Falcone, D.J.4    Sanborn, T.A.5    Spokojny, A.M.6    Bush H.L., Jr.7
  • 55
    • 0029033910 scopus 로고
    • Independent changes in type I and type II receptors for transforming growth factor β induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype
    • Centrella, M., Casinghino, S., Kim, J., Pham, T., Rosen, V., Wozney, J., and McCarthy, T. L. Independent changes in type I and type II receptors for transforming growth factor β induced by bone morphogenetic protein 2 parallel expression of the osteoblast phenotype. Mol. Cell Biol., 15: 3273-3281, 1995.
    • (1995) Mol. Cell Biol. , vol.15 , pp. 3273-3281
    • Centrella, M.1    Casinghino, S.2    Kim, J.3    Pham, T.4    Rosen, V.5    Wozney, J.6    McCarthy, T.L.7


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