Nutrition, genetics, and risks of cancer

Annual Review of Public Health

Volumn 21, Issue , 2000, Pages 47-64

  Rock, Cheryl L ^a   Lampe, Johanna W ^b   Patterson, Ruth E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Detoxifying enzymes; Diet; Genetic mutations; Nutrients; Polymorphisms

Indexed keywords

CANCER GENETICS; CANCER RISK; CONFERENCE PAPER; DIET; ENVIRONMENTAL FACTOR; ENZYME ACTIVITY; GENE FUNCTION; GENETIC RISK; HUMAN; MALIGNANT NEOPLASTIC DISEASE; NUTRITION; PRIORITY JOURNAL;

CYTOCHROME P-450 ENZYME SYSTEM; DIET; ENVIRONMENTAL EXPOSURE; GENETIC PREDISPOSITION TO DISEASE; GLUTATHIONE TRANSFERASE; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); NEOPLASMS; NUTRITION PHYSIOLOGY; OXIDOREDUCTASES ACTING ON CH-NH GROUP DONORS; POLYMORPHISM, GENETIC; PUBLIC HEALTH PRACTICE; RISK FACTORS; VARIATION (GENETICS);

EID: 0033927550     PISSN: 01637525     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.publhealth.21.1.47     Document Type: Conference Paper

References (92)

1. 1. Albanes D, Heinoen OP, Taylor PR, Virtamo J, Edwards BK, et al. 1996. Alpha-tocopherol and beta-carotene supplements and lung cancer incidence in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study: effects of base-line characteristics and study compliance. J. Natl. Cancer Inst. 88:1560-70
2. 2. Ambrosone CB, Fredenheim JL, Sinha R, Graham S, Marshall JR, et al. 1998. Breast cancer risk, meat consumption and N-acetyletransferase (NAT2) genetic polymorphisms. Int. J. Cancer 75:825-30
3. 3. American Cancer Society. 1996. Advisory Committee on Diet, Nutrition, and Cancer Prevention. 1996. Guidelines on diet, nutrition, and cancer prevention: reducing the risk of cancer with healthy food choices and physical activity. CA Cancer J. Clin. 46:325-41
4. 4. Anderson KE, Pantuck EJ, Conney AH, Kappas A. 1985. Nutrient regulation of chemical metabolism in humans. FASEB J. 44:130-33
5. 5. Astorg P, Gradelet S, Leclerc J, Siess MH. 1997. Effects of provitamin A or non-provitamin A carotenoids on liver xenobiotic-metabolizing enzymes in mice. Nutr. Cancer 27:245-49
6. 6. Bailey LB, Gregory JF. 1999. Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirements. J. Nutr. 129:919-22
7. 7. Beresford SAA, Boushey CJ. 1997. Homocysteine, folic acid, and cardiovascular disease risk. In Preventive Nutrition: The Comprehensive Guide for Health Professionals, ed. A Bendich, RJ Deckelbaum, pp. 193-224. Totowa, NJ: Humana
8. 8. Bogaards JJP, van Ommen B, Falke HE, Willems MI, van Bladeren PJ. 1990. Glutathione S-transferase subunit induction patterns of Brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: a new approach for the identification of inducing xenobiotics. Food Chem. Toxicol. 28:81-88
9. 9. Boushey CJ, Beresford SAA, Omenn GS, Motulsky AG. 1995. A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. J. Am. Med. Assoc. 274:1049-57
10. 10. Boyland E, Chasseaud LF. 1969. The role of glutathione and glutathione S-transferase in mercapturic acid biosynthesis. Adv. Enzymol. 32:173-219
11. 11. Bradlow HL, Michnovicz J, Telang NT, Osborne MP. 1991. Effect of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice. Carcinogenesis 12:1571-74
12. 12. Briefel RR, Flegal KM, Winn DM, Loria CM, Johnson CL, Sempos CT. 1992. Assessing the nation's diet: limitations of the food frequency questionnaire. J. Am. Diet. Assoc. 92:959-62
13. 13. Brockmöller J, Cacorbil I, Kerb R, Sachse C, Roots I. 1998. Polymorphisms in xenobiotic conjugation and disease predisposition. Toxicol. Letters 102:173-83
14. 14. Chen J, Giovannucci EL, Hunter DJ. 1999. MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis. J. Nutr. 129:560S-64S (Suppl.)
15. 15. Chen J, Stampfer MF, Hough HL, Garcia-Closas M, Willett WC, et al. 1998. A prospective study of N-acetyltransferase genotype, red meat intake, and risk of colorectal cancer. Cancer Res. 58:3307-11
16. 16. Coles B, Ketterer B. 1990. The role of glutathione and glutathione transferases in chemical carcinogenesis. Crit. Rev. Biochem. Mol. Biol. 25:47-70
17. 17. Fink L, Collins FS. 1997. The Human Genome Project: view from the National Institutes of Health. J. Am. Med. Womens Assoc. 52:4-15
18. 18. Freudenheim JL, Sinha R. 1999. Overview: interactions of diet and nutrition with genetic susceptibility in cancer. J. Nutr. 129:550S-51S (Suppl.)
19. 19. Frosst P, Blom HJ, Milos R, Goyette P, Sheppard CA, et al. 1995. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat. Genet. 10:111-13
20. 20. Gerhard GT, Malinow MR, DeLoughery TG, Evans AJ, Sexton AJ, et al. 1999. Higher total homocysteine concentrations and lower folate concentrations in pre-menopausal black women than in pre-menopausal white women. Am. J. Clin. Nutr. 70:252-60
21. 21. Giles WH, Kittner SJ, Ou CY, Croft JB, Brown V, et al. 1998. Thermolabile methylene tetrahydrofolate reductase polymorphism (C677T) and total homocysteine concentration among African-American and white women. Ethn. Dis. 8:149-57
22. 22. Gradelet S, Leclerc J, Siess MH, Astorg P. 1996. Beta-apo-8′-carotenal, but not beta-carotene, is a strong inducer of liver cytochromes P4501A1 and 1A2 in rat. Xenobiotica 26:909-19
23. 23. Greenwald P. 1996. The potential of dietary modification to prevent cancer. Prev. Med. 25:41-43
24. 24. Grinberg-Funes RA, Singh VN, Perera FP, Bell DA, Young TL, et al. 1994. Polycyclic aromatic hydrocarbon-DNA adducts in smokers and their relationship to micronutrient levels and the glutathione-S-transferase M1 genotype. Carcinogenesis 15:2449-54
25. 25. Guengerich FP. 1995. Influence of nutrients and other dietary materials on cytochrome P-450 enzymes. Am. J. Clin. Nutr. 61:651S-58S (Suppl.)
26. 26. Guengerich FP, Johnson WW, Ueng YF, Yamazaki H, Shimada T. 1996. Involvement of cytochrome P450, glutathione S-transferase, and epoxide hydrolase in the metabolism of aflatoxin B1 and relevance to risk of human liver cancer. Environ. Health Perspect. 104:557-62 (Suppl.)
27. 27. Harries LW, Stubbins MJ, Forman D, Howard GCW, Wolf CR. 1997. Identification of genetic polymorphisms at the glutathione S-transferase locus and association with susceptibility to bladder, testicular and prostate cancer. Carcinogenesis 18:641-44
28. 28. Harris CC. 1992. Chemical and physical carcinogenesis: advances and perspectives for the 1990s. Cancer Res. 51:5023s-44s (Suppl.)
29. 2 are the products of separate genes and that their expression in human liver is subject to inter-individual variation. Biochem. J. 264:437-45
30. 30. Hayes JD, Pulford DJ. 1995. The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance. Crit. Rev. Biochem. Mol. Biol. 30:445-600
31. 31. Hengstler JG, Arand M, Herrero ME, Oesch F. 1998. Polymorphisms of N-acetyltransferases, glutathione S-transferases, microsomal epoxide hydrolase and sulfotransferases: influence on cancer susceptibility. Recent Results Cancer Res. 154:47-85
32. 32. Hessner MJ, Luhm RA, Pearson SL, Endean DJ, Friedman KD, Mongomery RR. 1999. Prevalence of prothrombin G20210A, Factor V G1691A (Leiden), and methylenetetrahydrofolate reductase (MTHFR) C677T in seven different populations determined by multiplex allelespecific PCR. Thromb. Haemost. 81:733-38
33. 33. Jacques PF, Bostom AG, Williams RR, Ellison RC, Eckfeldt JH, et al. 1996. Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. Circulation 93:7-9
34. 34. Kampman E, Slattery ML, Bigler J, Leppert M, Samowitz W, et al. Meat consumption, genetic susceptibility, and colon cancer risk: a United States multicenter case-control study. Cancer Epidemiol. Biomarkers Prev. 8:15-24
35. 35. Kawajiri K, Eguchi H, Nakachi K, Sekiya T, Yamamoto M. 1996. Association of CYP1A1 germ line polymorphisms with mutations of the p53 gene in lung cancer. Cancer Res. 56:72-76
36. 36. Ketterer B, Meyer DJ, Clarke AG. 1988. Soluble glutathione transferase enzymes. In Glutathione Conjugation, ed. H Sies, B Ketterer, pp. 73-155. San Diego: Academic
37. 37. Khoury MJ. 1997. Genetic epidemiology. In Modern Epidemiology, ed. K Rothman, S. Greenland. Boston, MA: Little, Brown. 2nd ed.
38. 38. Kihara M, Kihara M, Noda K. 1995. Risk of smoking for squamous and small cell carcinomas of the lung modulated by combinations of CYP1A1 and GSTM1 gene polymorphisms in a Japanese population. Carcinogenesis 16:2331-36
39. 39. Kim YI, Pogribny IP, Basnakian AG, Miller JW, Selhub J, et al. 1997. Folate deficiency in rats induces DNA strand breaks and hypomethylation within the p53 tumor suppressor gene. Am. J. Clin. Nutr. 65:46-52
40. 40. Kluijtmans LA, van den Heuvel LPWJ, Boers GHJ, Frosst P, Stevens EMB, et al. 1996. Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease. Am. J. Hum. Genet. 58:35-41
41. 41. Lai C, Shields PG. 1999. The role of interindividual variation in human carcinogenesis. J. Nutr. 129:552S-55S (Suppl.)
42. 42. Le Marchand L, Sivaraman L, Pierce L, Seifried A, Lum A, et al. 1998. Associations of CYP1A1, GSTM1, and CYP2E1 polymorphisms with lung cancer suggest cell type specificities to tobacco carcinogens. Cancer Res. 53:4858-63
43. 43. Lin HJ, Probst-Hensch NM, Louie AD, Kau IH, Witte JS, et al. 1998. Glutathione transferase null genotype, broccoli, and lower prevalence of colorectal adenomas. Cancer Epidemiol. Biomarkers Prev. 7:647-52
44. 44. Liu H, Wormke M, Safe SH, Bjeldanes LF. 1994. Indole[3,2-b]carbazole: a dietary-derived factor that inhibits both antiestrogenie and estrogenic activity. J. Natl. Cancer Inst. 86:1758-65
45. 45. Ma J, Stampfer MJ, Selhub J, Malinow MR, Willett WC, Hennekens CH, Rozen R. 1996. Methylenetetrahydrofolate reductase polymorphism, plasma folate, homocysteine, and risk of myocardial infarction in US physicians. Cancer Res. 57:1098-102
46. 46. Makos M, Nelkin BD, Lerman MI, Latif F, Abar B, Baylin SB. 1992. Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer. Proc. Natl. Acad. Sci. USA 89:1929-33
47. 47. Malinow MR, Bostom AG, Krauss RM. 1999. Homocysteine, diet, and cardiovascular diseases. Circulation 99:178-82
48. 48. Malone KE, Daling JR, Thompson JD, O'Brien CA, Francisco LV, Ostrander EA. 1998. BRCA1 mutations and breast cancer in the general population: analyses in women before age 35 years and in women before age 45 years with first-degree family history. J. Am. Med. Assoc. 279:922-29
49. 49. Mannervik B, Awasthi YC, Board PG, Hayes JD, Di Ilio C, et al. 1992. Nomenclature for human glutathione transferases. Biochem. J. 282:305-8
50. 50. Mannervik B, Danielson UH. 1988. Glutathione S-transferases: structure and catalytic activity. CRC Crit. Rev. Biochem. 23:283-337
51. 51. McAndrew PE, Brandt JT, Pearl DK, Prior TW. 1996. The incidence of the gene for thermolabile methylenetetrahydrofolate reductase in African Americans. Thrombosis Res. 83:195-98
52. 52. McGlynn KA, Rosvold EAT, Lustbader ED, Hu Y, Clapper ML, et al. 1995. Susceptibility to hepatocellular carcinoma is associated with genetic variation in the enzymatic detoxification of aflatoxin B1. Proc. Natl. Acad. Sci. USA 92:2384-87
53. 53. Michnovicz JJ. 1998. Increased estrogen 2-hydroxylation in obese women using oral indole-3-carbinol. Int. J. Obesity 22:227-29
54. 54. Mollerup S, Ryberg D, Hewer A, Phillips DH, Haugen A. 1999. Sex differences in lung CYP1A1 expression and DNA adduct levels among lung cancer patients. Cancer Res. 59:3317-20
55. 55. Murray M, Cantrill E, Martini R, Farrell GC. 1991. Increased expression of cytochrome P450 IIIA2 in male rat liver after dietary vitamin A supplementation. Arch. Biochem. Biophys. 286:618-24
56. 56. Nelen WLDM, Blom HJ, Thomas CMG, Steegers EAP, Boers GHJ, Eskes TKAB. 1998. Methylenetetrahydrofolate reductase polymorphism affects the change in homocysteine and folate concentrations resulting from low dose folic acid supplementation in women with unexplained recurrent miscarriages. J. Nutr. 128:1336-41
57. 57. Nijhoff WA, Mulder TPJ, Verhagen H, Van Poppel G, Peters WHM. 1995. Effects of consumption of Brussels sprouts onplasma and urinary glutathione S-transferase class-α and -π in humans. Carcinogenesis 16:955-57
58. 58. Omenn GS. 1998. Chemoprevention of lung cancer: the rise and demise of beta-carotene. Annu. Rev. Public Health 19:73-99
59. 59. Omenn GS, Goodman GE, Thornquist MD, Balmes J, Cullen MR, et al. 1996. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N. Engl J. Med. 334:1150-55
60. 60. Paolini M, Cantelli-Forti G, Perocco P, Pedulli GF, Abdel-Rahman SZ, Legator MS. 1999. Co-carcinogenic effect of β-carotene. Nature 398:760-61
61. 61. Patterson RE, Eaton DL, Potter JD. 1999. The genetic revolution: change and challenge for the profession of dietetics. In Press J. Am. Diet. Assoc. 99:1412-20
62. 62. Pemble SE, Schroeder KR, Spencer SR, Meyer DJ, Hallier E. 1994. Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism. Biochem. J. 300:271-76
63. 63. Perera FP. 1997. Environment and cancer: Who are susceptible? Science 278:1068-73
64. 64. Philips DH. 1983. Fifty years of benzo(a)pyrene. Nature (Lond.) 303:468-72
65. 65. Pool-Zobel B, Bub A, Leigibel UM, Treptow-Van Lishaut S, Rechkemmer G. 1998. Mechanisms by which vegetable consumption reduces genetic damage in humans. Cancer Epidemiol. Biomarkers Prev. 7:891-99
66. 66. Potischman N, Brinton LA. 1996. Nutrition and cervical neoplasia. Cancer Causes Control 7:113-26
67. 67. Probst-Hensch NM, Tannenbaum SR, Chan KK, Coetzee GA, Ross RK, Yu MC. 1998. Absence of the glutathione S-transferase MI gene increases cytochrome P4501A2 activity among frequent consumers of cruciferous vegetables in a Caucasian population. Cancer Epidemiol. Biomarkers Prev. 7:635-38
68. 68. Raner GM, Vaz AD, Coon MJ. 1996. Metabolism of all-trans, 9-cis, and 13-cis isomers of retinal by purified isozymes of microsomal cytochrome P450 and mechanism-based inhibition of retinoid oxidation by citral. Mol. Pharmacol. 49: 515-22
69. 69. Rebbeck TR. 1997. Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility. Cancer Epidemiol. Biomarkers Prev. 6:733-43
70. 70. Reddy ACP, Lokesh BR. 1994. Alterations in lipid peroxides in rat liver by dietary n-3 fatty acids: modulation of antioxidant enzymes by curcumin, eugenol, and vitamin E. J. Nutr. Biochem. 5:181-88
71. 71. Reddy BS, Rao CV, Rivenson A, Kelloff G. 1993. Chemoprevention of colon carcinogenesis by organosulfur compounds. Cancer Res. 53:3493-98
72. 72. Roberts ES, Vaz AD, Coon MJ. 1992. Role of isozymes of rabbit microsomal cytochrome P-450 in the metabolism of retinoic acid, retinol, and retinal. Mol. Pharmacol. 41:427-33
73. 73. Rock CL. 1998. Nutritional factors in cancer prevention. Hem. Oncol. Clin. N. Am. 12:975-91
74. 74. Roland N, Nugon-Baudon L, Flinois J-P, Beaune P. 1994. Hepatic and intestinal cytochrome P-450, glutathione S-transferase and UDP-glucuronosyl transferase are affected by six types of dietary fiber in rats inoculated with human whole fecal flora. J. Nutr. 124:1581-87
75. 75. Rothman N, Hayes RB. 1995. Using biomarkers of genetic susceptibility to enhance the study of cancer etiology. Environ. Health Perspect. 8:291-95 (Suppl.)
76. 76. Rowe JD, Nieves E, Listowsky I. 1997. Subunit diversity and tissue distribution of human glutathione S-transferase s : interpretations based on electrospray ionization-MS and peptide sequence-specific antisera. Biochem. J. 325:481-86
77. 77. Sandler RS. 1996. Epidemiology and risk factors for colorectal cancer. Gastroenterol. Clin. N. Am. 25:717-35
78. 78. Seidegård J, Vorachek WR, Pero RW, Pearson WR. 1988. Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion. Proc. Natl. Acad. Sci. USA 85:7293-97
79. 79. Sellers TA. 1997. Genetic factors in the pathogenesis of breast cancer: their role and relative importance. J. Nutr. 127:929S-32S (Suppl.)
80. 80. Sinha R, Caporaso N. 1999. Diet, genetic susceptibility and human cancer etiology. J. Nutr. 129:5568-598 (Suppl.)
81. 81. Slattery ML, Potter JD, Samowitz W, Schaffer D, Leppert M. 1999. Methylenetetrahydrofolate reductase, diet, and risk of colon cancer. Cancer Epidemiol. Biomarkers Prev. 8:513-18
82. 82. Smith G, Stanley LA, Sim E, Strage RC, Wolf CR. 1995. Metabolic polymorphisms and cancer susceptibility. Cancer Surv. 25:27-65
83. 83. Steinmetz KA, Potter JD. 1996. Vegetables, fruit, and cancer prevention: a review. J. Am. Diet. Assoc. 96:1027-39
84. 1 exo-epoxide: association with reduced levels of hepatic aflatoxin-DNA adducts in vivo. Drug Metab. Dispos. 22:392-99
85. 85. Tsuchida S, Sato K. 1992. Glutathione transferases and cancer. CRC Crit. Rev. Biochem. Mol. Biol. 27:337-84
86. 86. van Ommen B, Bogaards JJP, Peters WHM, Blaauboer B, van Bladeren PJ. 1990. Quantification of human hepatic glutathione S-transferases. Biochem. J. 269:609-13
87. 87. Wang XD, Liu C, Bronson RT, Smith DE, Krinsky NI, Russell RM. 1999. Retinoid signaling and activator protein-1 expression in ferrets given β-carotene supplements and exposed to tobacco smoke. J. Natl. Cancer Inst. 91:60-66
88. 88. Watanabe M. 1998. Polymorphic CYP genes and disease predisposition - what have the studies shown so far? Toxicol. Lett. 102-103:167-71
89. 89. Welfare MR, Cooper J, Bassendine MF, Daly AK. 1997. Relationship between actylator status, smoking, diet and colorectal cancer risk in the northeast of England. Carcinogenesis 18:1351-54
90. 90. Yang CS, Brady JF, Hong JY. 1992. Dietary effects on cytochromes P450, xenobiotic metabolism, and toxicity. FASEB J. 6:737-44
91. 91. Zhang Y, Talalay P. 1994. Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Cancer Res. 54:1976s-81s (Suppl.)
92. 92. Zheng W, Deitz AC, Campbell DR, Wen WQ, Cerhan JR, et al. 1999. N-Acetytransferase 1 genetic polymorphism, cigarette smoking, well-done meat intake, and breast cancer risk. Cancer Epidemiol. Biomarkers Prev. 8:233-39