Absence of the glutathione S-transferase M1 gene increases cytochrome P4501A2 activity among frequent consumers of cruciferous vegetables in a Caucasian population

Cancer Epidemiology Biomarkers and Prevention

Volumn 7, Issue 7, 1998, Pages 635-638

  Probst Hensch, Nicole M ^a,b   Tannenbaum, Steven R ^d   Chan, Kenneth K ^e   Coetzee, Gerhard A ^c   Ross, Ronald K ^b   Yu, Mimi C ^b  

^a SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^d MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^e OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450; GLUTATHIONE TRANSFERASE;

ARTICLE; CANCER PREVENTION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME DEFECT; FEMALE; FOOD INTAKE; FOOD PREFERENCE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; VEGETARIAN;

BRASSICACEAE; CYTOCHROME P-450 CYP1A2; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; SMOKING;

EID: 0031926953     PISSN: 10559965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Prochaska, H. J., Santamaria, A. B., and Talalay, P. Rapid detection of inducers of enzymes that protect against carcinogens. Proc. Natl. Acad. Sci. USA, 89. 2394-2398, 1992
2. Kall, M A., Vang, O , and Clausen, J. Effects of dietary broccoli on human in vivo drug metabolizing enzymes evaluation of caffeine, oestrone and chlorzoxazone metabolism. Carcmogenesis (Lond), 17: 793-799, 1996
3. Landi, M. T., Zocchetti, C , Bernucci, I., Kadlubar, F. F., Tannenbaum, S., Skipper, B., Bartsch, H., Malaville, C , Shields, P., Caporaso, N E , and Vineis, P. Cytochrome P4501A2: enzyme induction and genetic control in determining 4-aminobiphenyl-hemoglobin adduct levels. Cancer Epidemiol, Biomark, Prev , 5: 696-698, 1996.
4. Kolm, R. H , Danielson, U H., Zhang, Y, Talalay, P, and Mannervik, B. Isothiocyanates as substrates for human glutathione transferees: structure-activity studies. Biochem. J., 311: 453-459, 1995.
5. Kalow, W., and Tang, B K. Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities. Clin. Pharmacol Tlier , 50: 508-519, 1991.
6. Bell, D. A , Taylor, J. A , Paulson, D. P., Robertson, C. N., Monler, J. L., and Lucier, G. W. Genetic risk and carcinogen exposure: a common inherited defect of the carcinogen-metabolism gene glutathione S-trausferase M1 (GSTM1) that increases susceptibility to bladder cancer. J. Natl. Cancer Inst., 85: 1159-1164, 1993.
7. Winer, B. J. Statistical Principles in Experimental Designs, Ed. 2, pp. 752-812. New York McGraw-Hill, 1971.
8. Yang, C. S., Brady, J F., and Hong, J-Y Dietary effects on cytochrome P450, xenobiotic metabolism, and toxicity, FASEB J., 6 737-744, 1992.
9. Bradlow, H. L , Sepkovic, D. W., Telang, N. T., and Osborne, M. P Indole-3-carbinol. A novel approach to breast cancer prevention. Ann. NY Acad. Sci., 768. 180-200, 1995.
10. Yang, C. S., Smith, T. J , and Hong, J-Y. Cytochrome P-450 enzymes as targets for chemoprevention against chemical carcinogenesis and toxicity: opportunities and limitations Cancer Res., 54. 1982s-1986s, 1994.
11. Jiao, D., Yu, M. C., Hankin, J. H., Low, S-H., and Chung, F-L. Total isothiocyanate contents in cooked vegetables frequently consumed in Singapore. J. Agric Food Chem , 46: 1055-1058, 1998.
12. Vistisen, P., Poulsen, H. E., and Loft, S. Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine. Carcinogenesis (Lond.), 9. 1561-1568, 1992.
13. Lin, H J., Han, C-Y , Bernstein, D. A., Hsiao, W , Lin, B. K , and Hardy, S. Ethnic distribution of the glutathione transferase Mu 1-1 (GSTMI) null genotype in 1473 individuals and application to bladder cancer susceptibility. Carcinogenesis (Lond.), 15: 1077-1081, 1994.
14. Nakajima, M , Yokoi, T., Mizutani, M., Shin, S., Kadlubar, F. F , and Kamataki, T. Phenotyping of CYP1A2 in Japanese population by analysis of caffeine urinary metabolites: absence of mutation prescribing the phenotype in the CYP1A2 gene. Cancer Epidemiol. Biomark. Prev., 3: 413-421, 1994
15. Butler, M. A., Lang, N. P., Young, J. F , Caporaso, N. F., Vineis, P , Hayes, R. B., Teitel, C. H , Massengill, J. P., Lawsen, M. F., and Kadlubar, F. F. Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites. Pharmaeogenetics, 2: 116-127, 1992.
16. Horn, E. P., Tucker, M A., Lambert, G., Silverman, D , Zametkin, D., Sinha, R., Hartge, T., Landi, M. T., and Caporaso, N. E. A. Study of gender-based cytochrome P4501A2 variability a possible mechanism for the male excess of bladder cancer. Cancer Epidemiol. Biomark. Prev., 4: 529-533, 1995.
17. Kadlubar, F. F., Young, J F., Lang, N P., Caporaso, N. E , Sinha, R , and Landi, M. T. Correspondence re: Letter to the editor by B. K. Tang and W. Kalow on CYP1A2 phenotyping using caffeine. Cancer Epidemiol Bioinark. Prev , 5: 757-758, 1996.
18. Brockmoller, J., Kerb. R., Drakoulis, N., Staffeldt, B., and Roots, I. Glutathione S-transferase M1, and its variants A and B as host factors and bladder cancer susceptibility: a case-control study. Cancer Res , 54: 4103-4111, 1994.
19. Yu, M. C., Ross, R K., Chan, K. K., Henderson, B. E., Skipper, P. L , Tannenbaum, S R., and Coetzee, G A. Glutathione S-transferase M1 genotype affects aminobiphenyl-hemoglobin adduct levels in White, Black, and Asian smokers and nonsmokers. Cancer Epidemiol. Biomark. Prev , 4: 861-864, 1995.