Sex differences in lung CYP1A1 expression and DNA adduct levels among lung cancer patients

Cancer Research

Volumn 59, Issue 14, 1999, Pages 3317-3320

  Mollerup, Steen ^a   Ryberg, David ^a   Hewer, Allan ^a   Phillips, David H ^b   Haugen, Aage ^b  

^a NATIONAL INSTITUTE OF OCCUPATIONAL HEALTH   (Norway)

^b INSTITUTE OF CANCER RESEARCH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE;

ADULT; ARTICLE; CANCER RISK; CIGARETTE SMOKING; DEMOGRAPHY; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION; GENETIC CODE; HUMAN; HUMAN EXPERIMENT; HYDROPHOBICITY; IMMUNOCYTOCHEMISTRY; LUNG CANCER; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEX DIFFERENCE; SMOKING HABIT; STATISTICAL ANALYSIS;

ADULT; AGED; CYTOCHROME P-450 CYP1A1; DNA; DNA ADDUCTS; DNA, NEOPLASM; ENZYME INDUCTION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; NITROSO COMPOUNDS; POLYCYCLIC HYDROCARBONS, AROMATIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMOKING;

EID: 0033565251     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Peto, R., Lopez, A. D., Boreham, J., Thun, M., Heath, C. Jr., and Doll, R. Mortality from smoking worldwide. Br. Med. Bull., 52: 12-21, 1996.
2. Engeland, A. Trends in the incidence of smoking-associated cancers in Norway, 1954-93. Int. J. Cancer, 68: 39-46, 1996.
3. Zang, E. A., and Wynder, E. L. Differences in lung cancer risk between men and women: examination of the evidence. J. Natl. Cancer Inst., 88: 183-192, 1996.
4. Prescott, E., Osler, M., Hein, H. O., Borch-Jonsen, K., Lange, P., Schnohr, P., and Vestbo, J. Gender and smoking-related risk of lung cancer: The Copenhagen Center for Prospective Population Studies. Epidemiology, 9: 79-83, 1998.
5. Phillips, D. H., Hewer, A., Martin, C. N., Garner, R. C., and King, M. M. Correlation of DNA adduct levels in human lung with cigarette smoking. Nature (Lond.), 336: 790-792, 1988.
6. Schoket, B., Phillips, D. H., Kostic, S., and Vincze, I. Smoking-associated bulky DNA adducts in bronchial tissue related to CYP1A1 Mspl and GSTM1 genotypes in lung patients. Carcinogenesis (Lond.), 19: 841-846, 1998.
7. Alexandrov, K., Rojas, M., Geneste, O., Castegnaro, M., Camus, A. M., Petruzzelli, S., Giuntini, C., and Bartsch, H. An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity. Cancer Res., 52: 6248-6253, 1992.
8. McLemore, T. L., Adelberg, S., Liu, M. C., McMahon, N. A., Yu, S. J., Hubbard, W. C., Czerwinski, M., Wood, T. G., Storeng, R., Lubet, R. A., Eggleston, J. C., Boyd, M. R., and Hines, R. N. Expression of CVPIAI gene in patients with lung cancer: evidence for cigarette smoke-induced gene expression in normal lung tissue and for altered gene regulation in primary pulmonary carcinomas. J. Natl. Cancer Inst., 82: 1333-1339, 1990.
9. Kriek, E., Rojas, M., Alexandrov, K., and Bartsch, H. Polycyclic aromatic hydrocarbon-DNA adducts in humans: relevance as biomarkers for exposure and cancer risk. Mutat. Res., 400: 215-231, 1998.
10. Tang, D., Santella, R. M., Blackwood, A. M., Young, T-L., Mayer, J., Jaretzki, A., Grantham, S., Tsai, W-Y., and Perera, F. P. A molecular epidemiological case-control study of lung cancer. Cancer Epidemiol. Biomark. Prev., 4: 341-346, 1995.
11. Ryberg, D., Hewer, A., Phillips, D. H., and Haugen, A. Different susceptibility to smoking-induced DNA damage among male and female lung cancer patients. Cancer Res., 54: 5801-5803, 1994.
12. Stücker, I., Kremers, P., Jacquet, M., Genee, S., de Waziers, I., Beaune, P., and Hemon, D. CYP1A1 inducibility, GSTM1, smoking and lung cancer. Results of a French case control study. Proc. Am. Assoc. Cancer Res., 39: 627, 1998.
13. Kure, E. H., Ryberg, D., Hewer, A., Phillips, D. H., Skaug, V., Bæra, R., and Haugen, A. p53 mutations in lung tumors: relationship to gender and lung DNA adduct levels. Carcinogenesis (Lond.), 17: 2201-2205, 1996.
14. Celi, F. S., Zenilman, M. E., and Shuldiner, A. R. A rapid and versatile method to synthesize internal standards for competitive PCR. Nucleic Acids Res., 21: 1047, 1993.
15. Willey, J. C., Coy, E. L., Frampton, M. W., Torres, A., Aposlolakos, M. J., Hoehm, G., Schuermann, W. H., Thilly, W. G., Olson, D. E., Hammersley, J. R., Crespi, C. L., and Utell, M. J. Quantitative RT-PCR measurement of cytochrome P450 1A1, 1B1, and 2B7, microsomal epoxide hydroxylase, and NADPH oxidoreductase expression in lung cells of smokers and nonsmokers. Am. J. Respir. Cell Mol. Biol., 17: 114-124, 1997.
16. Phillips, D. H., Schoket, B., Hewer, A., Bailey, E., Kostic, S., and Vincze, I. Influence of cigarette smoking on the level of DNA adducts in human bronchial epithelium and white blood cells. Int. J. Cancer, 46: 569-575, 1990.
17. Antilla, S., Hietanen, E., Vainio, H., Camus, A.-M., Gelboin, H. V., Park, S. S., Heikkilä, L., Karjalainen, A., and Bartsch, H. Smoking and peripheral type of cancer are related to high levels of pulmonary cytochrome P450IA in lung cancer patients. Int. J. Cancer, 47: 681-685, 1991.
18. Raunio, H., Hakkola, J., Hukkanen, J., Pelkonen, O., Edwards, R., Boobis, A., and Anttila, S. Expression of xenobiotic-metabolizing cytochrome P450s in human pulmonary tissues. Arch. Toxicol. Suppl., 20: 465-469, 1998.
19. Mollerup, S., Ryberg, D., Hewer, A., Phillips, D. H., Skaug, V., and Haugen, A. Gender differences in CYP1A1 expression among lung cancer patients. Proc. Am. Assoc. Cancer Res., 39: 337, 1998.
20. 32P-postlabeling and aryl hydrocarbon hydroxylase activity in lung parenchyma of smokers and ex-smokers. Carcinogenesis (Lond.), 12: 1301-1305, 1991.
21. Guinee, D. G., Jr., Travis, W. D., Trivers, G. E., De Benedetti, V. M. G., Cawley, H., Welsh, J. A., Bennett, W. P., Jett, J., Colby, T. V., Tazelaar, H., Abbondanzo, S. L., Pairolero, P., Trastek, V., Caparaso, N. E., Liotta, L. A., and Harris, C. C. Gender comparisons in human lung cancer: analysis of p53 mutations, anti-p53 antibodies and C-erbB-2 expression. Carcinogenesis (Lond.), 16: 993-1002, 1995.
22. Taioli, E., and Wynder, E. L. Re: endocrine factors and adenocarcinoma of the lung in women. J. Natl. Cancer Inst., 86: 869-870, 1994.
23. Thomsen, J. S., Wang, X., Hines, R. N., and Safe, S. Restoration of aryl hydrocarbon (Ah) responsiveness in MDA-MB-231 human breast cancer cells by transient expression of the estrogen receptor. Carcinogenesis (Lond.), 15: 933-937, 1994.
24. Kaiser, U., Hofmann, J., Schilli, M., Wegmann, B., Klotz, U., Wedel, S., Virmani, A. K., Wollmer, E., Branscheid, D., Gazdar, A. F., and Havemann, K. Steroid-hormone receptors in cell lines and tumor biopsies of human lung cancer. Int. J. Cancer, 67: 357-364, 1996.
25. Brandenberger, A. W., Tee, M. K., Lee, J. Y., Chao, V., and Jaffe, R. B. Tissue distribution of estrogen receptor α (ER-α) and β(ER-β) mRNA in the midgestational human fetus. J. Clin. Endocrinol. & Metab., 82: 3509-3512, 1997.
26. Kuiper, G. G., Carlsson, B., Grandien, K., Enmark, E., Haggblad, J., Nilsson, S., and Gustafsson, J. A. Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptor α and β. Endocrinology, 138: 863-870, 1997.