메뉴 건너뛰기




Volumn 301, Issue 1, 2000, Pages 71-84

Developmental motoneuron cell death and neurotrophic factors

Author keywords

Lumbar spinal cord; Motoneuron cell death; Neurotrophic factors; Rat

Indexed keywords

NEUROTROPHIC FACTOR;

EID: 0033912318     PISSN: 0302766X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004410000217     Document Type: Review
Times cited : (121)

References (130)
  • 1
    • 0027962477 scopus 로고
    • Differential effect of NGF and EGF on ERK in neuronally differentiated PC12 cells
    • Aletta JM (1994) Differential effect of NGF and EGF on ERK in neuronally differentiated PC12 cells. Neuroreport 5:2090-2092
    • (1994) Neuroreport , vol.5 , pp. 2090-2092
    • Aletta, J.M.1
  • 2
    • 0031957298 scopus 로고    scopus 로고
    • Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis
    • Aoki M, Lin CL, Rothstein JD, Geller BA, Hosler BA, Munsat TL, Horvitz HR, Brown RH Jr (1998) Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis. Ann Neurol 43: 645-653
    • (1998) Ann Neurol , vol.43 , pp. 645-653
    • Aoki, M.1    Lin, C.L.2    Rothstein, J.D.3    Geller, B.A.4    Hosler, B.A.5    Munsat, T.L.6    Horvitz, H.R.7    Brown, R.H.8
  • 3
    • 0025514410 scopus 로고
    • Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: Comparison with other neurotrophic factors and cytokines
    • Arakawa Y, Sendtner M, Thoenen H (1990) Survival effect of ciliary neurotrophic factor (CNTF) on chick embryonic motoneurons in culture: comparison with other neurotrophic factors and cytokines. J Neurosci 10:3507-3515
    • (1990) J Neurosci , vol.10 , pp. 3507-3515
    • Arakawa, Y.1    Sendtner, M.2    Thoenen, H.3
  • 6
    • 0032559622 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death
    • Bamji SX, Majdan M, Pozniak CD, Belliveau DJ, Aloyz R, Kohn J, Causing CG, Miller FD (1998) The p75 neurotrophin receptor mediates neuronal apoptosis and is essential for naturally occurring sympathetic neuron death. J Cell Biol 140:911-923
    • (1998) J Cell Biol , vol.140 , pp. 911-923
    • Bamji, S.X.1    Majdan, M.2    Pozniak, C.D.3    Belliveau, D.J.4    Aloyz, R.5    Kohn, J.6    Causing, C.G.7    Miller, F.D.8
  • 7
    • 0022137480 scopus 로고
    • Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation
    • Bar-Sagi D, Feramisco JR (1985) Microinjection of the ras oncogene protein into PC12 cells induces morphological differentiation. Cell 42:841-848
    • (1985) Cell , vol.42 , pp. 841-848
    • Bar-Sagi, D.1    Feramisco, J.R.2
  • 8
    • 0025524602 scopus 로고
    • The nerve growth factor family
    • Barde Y-A (1990) The nerve growth factor family. Prog Growth Factor Res 2:237-248
    • (1990) Prog Growth Factor Res , vol.2 , pp. 237-248
    • Barde, Y.-A.1
  • 9
    • 0028841897 scopus 로고
    • Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositol-phospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells
    • Baxter RM, Cohen P, Obermeier A, Ullrich A, Downes CP, Doza YN (1995) Phosphotyrosine residues in the nerve-growth-factor receptor (Trk-A). Their role in the activation of inositol-phospholipid metabolism and protein kinase cascades in phaeochromocytoma (PC12) cells. Eur J Biochem 234:84-91
    • (1995) Eur J Biochem , vol.234 , pp. 84-91
    • Baxter, R.M.1    Cohen, P.2    Obermeier, A.3    Ullrich, A.4    Downes, C.P.5    Doza, Y.N.6
  • 10
    • 0028097839 scopus 로고
    • A controlled trial of riluzole in amyotrophic lateral sclerosis
    • Bensimon G, Lacomblez L, Meininger V, ALS-Riluzole Study Group (1994) A controlled trial of riluzole in amyotrophic lateral sclerosis. N Engl J Med 330:585-591
    • (1994) N Engl J Med , vol.330 , pp. 585-591
    • Bensimon, G.1    Lacomblez, L.2    Meininger, V.3
  • 11
    • 0027256842 scopus 로고
    • Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons
    • Borasio GD, Markus A, Wittinghofer A, Barde YA, Heumann R (1993) Involvement of ras p21 in neurotrophin-induced response of sensory, but not sympathetic neurons. J Cell Biol 121:665-672
    • (1993) J Cell Biol , vol.121 , pp. 665-672
    • Borasio, G.D.1    Markus, A.2    Wittinghofer, A.3    Barde, Y.A.4    Heumann, R.5
  • 14
    • 0028982268 scopus 로고
    • Differential regulation of p21ras activation in neurons by nerve growth factor and brain-derived neurotrophic factor
    • Carter BD, Zirrgiebel U, Barde YA (1995) Differential regulation of p21ras activation in neurons by nerve growth factor and brain-derived neurotrophic factor. J Biol Chem 270:21751-21757
    • (1995) J Biol Chem , vol.270 , pp. 21751-21757
    • Carter, B.D.1    Zirrgiebel, U.2    Barde, Y.A.3
  • 15
    • 0032213730 scopus 로고    scopus 로고
    • Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain
    • Cattaneo E, Pelicci PG (1998) Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain. Trends Neurosci 21:476-481
    • (1998) Trends Neurosci , vol.21 , pp. 476-481
    • Cattaneo, E.1    Pelicci, P.G.2
  • 17
    • 0026533608 scopus 로고
    • Amyotrophic lateral sclerosis and glutamate -too much of a good thing
    • Choi DW (1992) Amyotrophic lateral sclerosis and glutamate -too much of a good thing. N Engl J Med 326:1493-1495
    • (1992) N Engl J Med , vol.326 , pp. 1493-1495
    • Choi, D.W.1
  • 18
    • 0030860786 scopus 로고    scopus 로고
    • Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain
    • Conti L, De Fraja C, Gulisano M, Migliaccio E, Govoni S, Cattaneo E (1997) Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain. Proc Natl Acad Sci USA 94:8185-8190
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 8185-8190
    • Conti, L.1    De Fraja, C.2    Gulisano, M.3    Migliaccio, E.4    Govoni, S.5    Cattaneo, E.6
  • 19
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell - Intrinsic death machinery
    • Datta SR, Dudek H, Tao X, Masters S, Fu H, Gotoh Y, Greenberg ME (1997) Akt phosphorylation of BAD couples survival signals to the cell - intrinsic death machinery. Cell 91:231-241
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 20
    • 13144259635 scopus 로고    scopus 로고
    • TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons
    • Davey F, Davies AM (1998) TrkB signalling inhibits p75-mediated apoptosis induced by nerve growth factor in embryonic proprioceptive neurons. Curr Biol 8:915-918
    • (1998) Curr Biol , vol.8 , pp. 915-918
    • Davey, F.1    Davies, A.M.2
  • 21
    • 0030878081 scopus 로고    scopus 로고
    • The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity
    • Dechant G, Tsoulfas P, Parada LF, Barde YA (1997) The neurotrophin receptor p75 binds neurotrophin-3 on sympathetic neurons with high affinity and specificity. J Neurosci 17:5281-5287
    • (1997) J Neurosci , vol.17 , pp. 5281-5287
    • Dechant, G.1    Tsoulfas, P.2    Parada, L.F.3    Barde, Y.A.4
  • 22
    • 0031845159 scopus 로고    scopus 로고
    • Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation
    • Deckwerth TL, Easton RM, Knudson CM, Korsmeyer SJ, Johnson EM Jr (1998) Placement of the BCL2 family member BAX in the death pathway of sympathetic neurons activated by trophic factor deprivation. Exp Neurol 152:150-162
    • (1998) Exp Neurol , vol.152 , pp. 150-162
    • Deckwerth, T.L.1    Easton, R.M.2    Knudson, C.M.3    Korsmeyer, S.J.4    Johnson, E.M.5
  • 24
    • 0032192529 scopus 로고    scopus 로고
    • Evidence of a novel event during neuronal death: Development of competence-to-die in response to cytoplasmic cytochrome c [see comments]
    • Deshmukh M, Johnson EM Jr (1998) Evidence of a novel event during neuronal death: development of competence-to-die in response to cytoplasmic cytochrome c [see comments]. Neuron 21:695-705
    • (1998) Neuron , vol.21 , pp. 695-705
    • Deshmukh, M.1    Johnson, E.M.2
  • 25
    • 0030810926 scopus 로고    scopus 로고
    • X-linked IAP is a direct inhibitor of cell-death proteases
    • Devereaux QL, Takahashi R, Salvesen GS, Reed JC (1997) X-linked IAP is a direct inhibitor of cell-death proteases. Nature 388:300-304
    • (1997) Nature , vol.388 , pp. 300-304
    • Devereaux, Q.L.1    Takahashi, R.2    Salvesen, G.S.3    Reed, J.C.4
  • 28
    • 0028343507 scopus 로고
    • Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death
    • Dubois-Dauphin M, Frankowski H, Tsujimoto Y, Huarte J, Martinou J-C (1994) Neonatal motoneurons overexpressing the bcl-2 protooncogene in transgenic mice are protected from axotomy-induced cell death. Proc Natl Acad Sci USA 91: 3309-3313
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 3309-3313
    • Dubois-Dauphin, M.1    Frankowski, H.2    Tsujimoto, Y.3    Huarte, J.4    Martinou, J.-C.5
  • 30
    • 0030777650 scopus 로고    scopus 로고
    • Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS
    • Durham HD, Roy J, Dong L, Figlewicz DA (1997) Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS. J Neuropathol Exp Neurol 56:523-530
    • (1997) J Neuropathol Exp Neurol , vol.56 , pp. 523-530
    • Durham, H.D.1    Roy, J.2    Dong, L.3    Figlewicz, D.A.4
  • 32
    • 0343237235 scopus 로고
    • The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival
    • Edgar D, Timpl R, Thoenen H (1984) The heparin-binding domain of laminin is responsible for its effects on neurite outgrowth and neuronal survival. EMBO J 3:1463-1468
    • (1984) EMBO J , vol.3 , pp. 1463-1468
    • Edgar, D.1    Timpl, R.2    Thoenen, H.3
  • 33
    • 0025752461 scopus 로고
    • Two C. elegans genes control the programmed deaths of specific cells in the pharynx
    • Ellis RE, Horvitz HR (1991) Two C. elegans genes control the programmed deaths of specific cells in the pharynx. Development 112:591-603
    • (1991) Development , vol.112 , pp. 591-603
    • Ellis, R.E.1    Horvitz, H.R.2
  • 36
    • 0031773432 scopus 로고    scopus 로고
    • Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture
    • Estevez AG, Spear N, Manuel SM, Barbeito L, Radi R, Beckman JS (1998b) Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture. Prog Brain Res 118:269-280
    • (1998) Prog Brain Res , vol.118 , pp. 269-280
    • Estevez, A.G.1    Spear, N.2    Manuel, S.M.3    Barbeito, L.4    Radi, R.5    Beckman, J.S.6
  • 38
    • 0031982883 scopus 로고    scopus 로고
    • Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor
    • Ferri CC, Moore FA, Bisby MA (1998) Effects of facial nerve injury on mouse motoneurons lacking the p75 low-affinity neurotrophin receptor. J Neurobiol 34:1-9
    • (1998) J Neurobiol , vol.34 , pp. 1-9
    • Ferri, C.C.1    Moore, F.A.2    Bisby, M.A.3
  • 40
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • Frade JM, Barde YA (1998a) Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron 20: 35-42
    • (1998) Neuron , vol.20 , pp. 35-42
    • Frade, J.M.1    Barde, Y.A.2
  • 41
    • 0031934936 scopus 로고    scopus 로고
    • Microglia-derived nerve growth factor causes cell death in the developing retina
    • Frade JM, Barde YA (1998b) Microglia-derived nerve growth factor causes cell death in the developing retina. Neuron 20: 35-42
    • (1998) Neuron , vol.20 , pp. 35-42
    • Frade, J.M.1    Barde, Y.A.2
  • 42
    • 0032968762 scopus 로고    scopus 로고
    • Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord
    • Frade JM, Barde YA (1999) Genetic evidence for cell death mediated by nerve growth factor and the neurotrophin receptor p75 in the developing mouse retina and spinal cord. Development 126:683-690
    • (1999) Development , vol.126 , pp. 683-690
    • Frade, J.M.1    Barde, Y.A.2
  • 43
    • 0029787071 scopus 로고    scopus 로고
    • Induction of cell death by endogenous nerve growth factor through its p75 receptor
    • Frade JM, Rodriguez Tebar A, Barde YA (1996) Induction of cell death by endogenous nerve growth factor through its p75 receptor. Nature 383:166-168
    • (1996) Nature , vol.383 , pp. 166-168
    • Frade, J.M.1    Rodriguez Tebar, A.2    Barde, Y.A.3
  • 44
    • 1842407161 scopus 로고    scopus 로고
    • Inhibition of ICE slows ALS in mice
    • [letter] [published erratum appears in nature 1998 apr 9;392(6676):560]
    • Friedlander RM, Brown RH, Gagliardini V, Wang J, Yuan J (1997) Inhibition of ICE slows ALS in mice [letter] [published erratum appears in Nature 1998 Apr 9;392(6676):560]. Nature 388:31
    • (1997) Nature , vol.388 , pp. 31
    • Friedlander, R.M.1    Brown, R.H.2    Gagliardini, V.3    Wang, J.4    Yuan, J.5
  • 45
    • 0033604518 scopus 로고    scopus 로고
    • Neurotrophin signaling via Trks and p75
    • Friedman WJ, Greene LA (1999) Neurotrophin signaling via Trks and p75. Exp Cell Res 253:131-142
    • (1999) Exp Cell Res , vol.253 , pp. 131-142
    • Friedman, W.J.1    Greene, L.A.2
  • 47
    • 0028808732 scopus 로고
    • Early events in neurotrophin signalling via Trk and p75 receptors
    • Greene LA, Kaplan DR (1995) Early events in neurotrophin signalling via Trk and p75 receptors. Curr Opin Neurobiol 5:579-587
    • (1995) Curr Opin Neurobiol , vol.5 , pp. 579-587
    • Greene, L.A.1    Kaplan, D.R.2
  • 48
    • 0034603157 scopus 로고    scopus 로고
    • Neuronal calcium activates a Rap1 and B-Raf signaling pathway via the cyclic adenosine monophosphate-dependent protein kinase
    • Grewal SS, Horgan AM, York RD, Withers GS, Banker GA, Stork PJ (2000) Neuronal calcium activates a Rap1 and B-Raf signaling pathway via the cyclic adenosine monophosphate-dependent protein kinase. J Biol Chem 275:3722-3728
    • (2000) J Biol Chem , vol.275 , pp. 3722-3728
    • Grewal, S.S.1    Horgan, A.M.2    York, R.D.3    Withers, G.S.4    Banker, G.A.5    Stork, P.J.6
  • 49
    • 0000764144 scopus 로고    scopus 로고
    • Muscle-specific cell ablation conditional upon Cre-mediated DNA recombination in transgenic mice leads to massive spinal and cranial motoneuron loss neuronal cell death
    • Grieshammer U, Lewandoski M, Prevette D, Oppenheim RW, Martin GR, Pettmann B, Henderson CE (1998) Muscle-specific cell ablation conditional upon Cre-mediated DNA recombination in transgenic mice leads to massive spinal and cranial motoneuron loss neuronal cell death. Neuron 20:633-647
    • (1998) Neuron , vol.20 , pp. 633-647
    • Grieshammer, U.1    Lewandoski, M.2    Prevette, D.3    Oppenheim, R.W.4    Martin, G.R.5    Pettmann, B.6    Henderson, C.E.7
  • 51
    • 84982342043 scopus 로고
    • The effects of wing bud extirpation on the development of the central nervous system in chick embryos
    • Hamburger V (1934) The effects of wing bud extirpation on the development of the central nervous system in chick embryos. J Exp Zool 68:449-494
    • (1934) J Exp Zool , vol.68 , pp. 449-494
    • Hamburger, V.1
  • 52
    • 70449239593 scopus 로고
    • Regression versus peripheral control of differentiation in motor hyperplasia
    • Hamburger V (1958) Regression versus peripheral control of differentiation in motor hyperplasia. Am J Anat 102:365-410
    • (1958) Am J Anat , vol.102 , pp. 365-410
    • Hamburger, V.1
  • 53
    • 17344369235 scopus 로고    scopus 로고
    • Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro
    • Hanson MG Jr, Shen S, Wiemelt AP, McMorris FA, Barres BA (1998) Cyclic AMP elevation is sufficient to promote the survival of spinal motor neurons in vitro. J Neurosci 18:7361-7371
    • (1998) J Neurosci , vol.18 , pp. 7361-7371
    • Hanson, M.G.1    Shen, S.2    Wiemelt, A.P.3    McMorris, F.A.4    Barres, B.A.5
  • 56
    • 0027131764 scopus 로고
    • Members of several gene families influence survival of rat motoneurons in vitro and in vivo
    • Hughes RA, Sendtner M, Thoenen H (1993) Members of several gene families influence survival of rat motoneurons in vitro and in vivo. J Neurosci Res 36:663-671
    • (1993) J Neurosci Res , vol.36 , pp. 663-671
    • Hughes, R.A.1    Sendtner, M.2    Thoenen, H.3
  • 57
    • 0028916844 scopus 로고
    • Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease
    • Ikeda K, Klinkosz B, Greene T, Cedarbaum JM, Wong V, Lindsay RM, Mitsumoto H (1995) Effects of brain-derived neurotrophic factor on motor dysfunction in wobbler mouse motor neuron disease. Ann Neurol 37:505-511
    • (1995) Ann Neurol , vol.37 , pp. 505-511
    • Ikeda, K.1    Klinkosz, B.2    Greene, T.3    Cedarbaum, J.M.4    Wong, V.5    Lindsay, R.M.6    Mitsumoto, H.7
  • 58
    • 0034639745 scopus 로고    scopus 로고
    • Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: An animal model for spinal muscular atrophy type III
    • Jablonka S, Schrank B, Kralewski M, Rossoll W, Sendtner M (2000) Reduced survival motor neuron (Smn) gene dose in mice leads to motor neuron degeneration: an animal model for spinal muscular atrophy type III. Hum Mol Genet 9:341-346
    • (2000) Hum Mol Genet , vol.9 , pp. 341-346
    • Jablonka, S.1    Schrank, B.2    Kralewski, M.3    Rossoll, W.4    Sendtner, M.5
  • 59
    • 0026713810 scopus 로고
    • N-Methyl-D-aspartate receptors are transiently expressed in the developing spinal cord ventral horn
    • Kalb RG, Lidow MS, Halsted M, Hockfield S (1992) N-Methyl-D-aspartate receptors are transiently expressed in the developing spinal cord ventral horn. Proc Natl Acad Sci USA 89:8502-8506
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 8502-8506
    • Kalb, R.G.1    Lidow, M.S.2    Halsted, M.3    Hockfield, S.4
  • 62
    • 0030756459 scopus 로고    scopus 로고
    • Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis
    • Kostic V, Jackson-Lewis V, De Bilbao F, Dubois-Dauphin M, Przedborski S (1997) Bcl-2: prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis. Science 277:559-562
    • (1997) Science , vol.277 , pp. 559-562
    • Kostic, V.1    Jackson-Lewis, V.2    De Bilbao, F.3    Dubois-Dauphin, M.4    Przedborski, S.5
  • 63
    • 84982340024 scopus 로고
    • The origin and development of the visceral system in the spinal cord of the chick embryo
    • Levi-Montalcini R (1950) The origin and development of the visceral system in the spinal cord of the chick embryo. J Morphol 253-284
    • (1950) J Morphol , pp. 253-284
    • Levi-Montalcini, R.1
  • 67
    • 0026766860 scopus 로고
    • The nerve growth factor family of receptors
    • Meakin SO, Shooter EM (1992) The nerve growth factor family of receptors. Trends Neurosci 15:323-331
    • (1992) Trends Neurosci , vol.15 , pp. 323-331
    • Meakin, S.O.1    Shooter, E.M.2
  • 68
    • 0032030754 scopus 로고    scopus 로고
    • Effect of glutamate on dendritic growth in embryonic rat motoneurons
    • Metzger F, Wiese S, Sendtner M (1998) Effect of glutamate on dendritic growth in embryonic rat motoneurons. J Neurosci 18:1735-1742
    • (1998) J Neurosci , vol.18 , pp. 1735-1742
    • Metzger, F.1    Wiese, S.2    Sendtner, M.3
  • 69
    • 0033986108 scopus 로고    scopus 로고
    • Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ
    • Metzger F, Kulik A, Sendtner M, Ballanyi K (2000) Contribution of Ca(2+)-permeable AMPA/KA receptors to glutamate-induced Ca(2+) rise in embryonic lumbar motoneurons in situ. J Neurophysiol 83:50-59
    • (2000) J Neurophysiol , vol.83 , pp. 50-59
    • Metzger, F.1    Kulik, A.2    Sendtner, M.3    Ballanyi, K.4
  • 70
    • 0029761433 scopus 로고    scopus 로고
    • Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2
    • Metzstein MM, Hengartner MO, Tsung N, Ellis RE, Horvitz HR (1996) Transcriptional regulator of programmed cell death encoded by Caenorhabditis elegans gene ces-2. Nature 382: 545-547
    • (1996) Nature , vol.382 , pp. 545-547
    • Metzstein, M.M.1    Hengartner, M.O.2    Tsung, N.3    Ellis, R.E.4    Horvitz, H.R.5
  • 71
    • 0028867186 scopus 로고
    • Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture
    • Meyer-Franke A, Kaplan MR, Pfrieger FW, Barres BA (1995) Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture. Neuron 15:805-819
    • (1995) Neuron , vol.15 , pp. 805-819
    • Meyer-Franke, A.1    Kaplan, M.R.2    Pfrieger, F.W.3    Barres, B.A.4
  • 73
    • 1842456916 scopus 로고    scopus 로고
    • Inactivation of the bcl-2 gene results in progressive degeneration of motoneurons, sensory and sympathetic neurons during early postnatal development
    • Michaelidis TM, Sendtner M, Cooper JD, Airaksinen M, Holtmann B, Meyer M, Thoenen H (1996) Inactivation of the bcl-2 gene results in progressive degeneration of motoneurons, sensory and sympathetic neurons during early postnatal development. Neuron 17:75-89
    • (1996) Neuron , vol.17 , pp. 75-89
    • Michaelidis, T.M.1    Sendtner, M.2    Cooper, J.D.3    Airaksinen, M.4    Holtmann, B.5    Meyer, M.6    Thoenen, H.7
  • 77
    • 0022460234 scopus 로고
    • Effects of nerve growth factor on the survival and synaptic function of Ia sensory neurons axotomized in neonatal rats
    • Miyata Y, Kashihara Y, Homma S, Kuno M (1986) Effects of nerve growth factor on the survival and synaptic function of Ia sensory neurons axotomized in neonatal rats. J Neurosci 6:2012-2018
    • (1986) J Neurosci , vol.6 , pp. 2012-2018
    • Miyata, Y.1    Kashihara, Y.2    Homma, S.3    Kuno, M.4
  • 79
    • 0030892234 scopus 로고    scopus 로고
    • Apoptosis by death factor
    • Nagata S (1997) Apoptosis by death factor. Cell 88:355-365
    • (1997) Cell , vol.88 , pp. 355-365
    • Nagata, S.1
  • 80
    • 0029809187 scopus 로고    scopus 로고
    • N-Shc: A neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/Mapk pathway
    • Nakamura T, Sanokawa R, Sasaki Y, Ayusawa D, Oishi M, Mori N (1996) N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/Mapk pathway. Oncogene 1111-1121
    • (1996) Oncogene , pp. 1111-1121
    • Nakamura, T.1    Sanokawa, R.2    Sasaki, Y.3    Ayusawa, D.4    Oishi, M.5    Mori, N.6
  • 81
    • 0031818619 scopus 로고    scopus 로고
    • gp130 and the IL-6 family of cytokines: Signaling mechanisms and thrombopoietic activities
    • Nakashima K, Taga T (1998) gp130 and the IL-6 family of cytokines: signaling mechanisms and thrombopoietic activities. Semin Hematol 35:210-221
    • (1998) Semin Hematol , vol.35 , pp. 210-221
    • Nakashima, K.1    Taga, T.2
  • 83
    • 0032191132 scopus 로고    scopus 로고
    • Surviving the cytochrome seas [comment]
    • Newmeyer DD, Green DR (1998) Surviving the cytochrome seas [comment]. Neuron 21:653-655
    • (1998) Neuron , vol.21 , pp. 653-655
    • Newmeyer, D.D.1    Green, D.R.2
  • 84
    • 0033999093 scopus 로고    scopus 로고
    • Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motoneurons in the chick embryo
    • Novak KD, Prevette D, Wang S, Gould TW, Oppenheim RW (2000) Hepatocyte growth factor/scatter factor is a neurotrophic survival factor for lumbar but not for other somatic motoneurons in the chick embryo. J Neurosci 20:326-337
    • (2000) J Neurosci , vol.20 , pp. 326-337
    • Novak, K.D.1    Prevette, D.2    Wang, S.3    Gould, T.W.4    Oppenheim, R.W.5
  • 85
    • 0028293929 scopus 로고
    • Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLCgamma
    • Obermeier A, Bradshaw RA, Seedorf K, Choidas A, Schlessinger J, Ullrich A (1994) Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLCgamma. EMBO J 13:1585-1590
    • (1994) EMBO J , vol.13 , pp. 1585-1590
    • Obermeier, A.1    Bradshaw, R.A.2    Seedorf, K.3    Choidas, A.4    Schlessinger, J.5    Ullrich, A.6
  • 86
    • 0027374486 scopus 로고
    • Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex
    • Obermeier A, Lammers R, Wiesmuller KH, Jung G, Schlessinger J, Ullrich A (1993) Identification of Trk binding sites for SHC and phosphatidylinositol 3′-kinase and formation of a multimeric signaling complex. J Biol Chem 268:22963-22966
    • (1993) J Biol Chem , vol.268 , pp. 22963-22966
    • Obermeier, A.1    Lammers, R.2    Wiesmuller, K.H.3    Jung, G.4    Schlessinger, J.5    Ullrich, A.6
  • 87
    • 0015987922 scopus 로고
    • Cell death of the embryonic chick spinal cord
    • O'Connor TM, Wyttenbach CR (1974) Cell death of the embryonic chick spinal cord. J Cell Biol 60:448-459
    • (1974) J Cell Biol , vol.60 , pp. 448-459
    • O'Connor, T.M.1    Wyttenbach, C.R.2
  • 88
    • 0021635544 scopus 로고
    • Cell death of motoneurons in the chick embryo spinal cord. IX. The loss of motoneurons following removal of afferent inputs
    • Okado N, Oppenheim RW (1984) Cell death of motoneurons in the chick embryo spinal cord. IX. The loss of motoneurons following removal of afferent inputs. J Neurosci 4:1639-1652
    • (1984) J Neurosci , vol.4 , pp. 1639-1652
    • Okado, N.1    Oppenheim, R.W.2
  • 89
    • 0022354769 scopus 로고
    • Naturally occurring cell death during neural development
    • Oppenheim RW (1985) Naturally occurring cell death during neural development. Trends Neurosci 8:487-493
    • (1985) Trends Neurosci , vol.8 , pp. 487-493
    • Oppenheim, R.W.1
  • 90
    • 0024392698 scopus 로고
    • Early regional variations in motoneuron numbers arise by differential proliferation in the chick embryo spinal cord
    • Oppenheim RW, Cole T, Prevette D (1989) Early regional variations in motoneuron numbers arise by differential proliferation in the chick embryo spinal cord. Dev Biol 133:468-474
    • (1989) Dev Biol , vol.133 , pp. 468-474
    • Oppenheim, R.W.1    Cole, T.2    Prevette, D.3
  • 91
    • 0033517189 scopus 로고    scopus 로고
    • NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase
    • Ozes ON, Mayo LD, Gustin JA, Pfeffer SR, Pfeffer LM, Donner DB (1999) NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase. Nature 401:82-85
    • (1999) Nature , vol.401 , pp. 82-85
    • Ozes, O.N.1    Mayo, L.D.2    Gustin, J.A.3    Pfeffer, S.R.4    Pfeffer, L.M.5    Donner, D.B.6
  • 93
    • 0027973511 scopus 로고
    • Cell death of spinal motoneurons in the chick embryo following deafferentiation: Rescue effects of tissue extracts, soluble proteins, and neurotrophic agents
    • Qin-Wei Y, Johnson J, Prevette D, Oppenheim RW (1994) Cell death of spinal motoneurons in the chick embryo following deafferentiation: rescue effects of tissue extracts, soluble proteins, and neurotrophic agents. J Neurosci 14:7629-7640
    • (1994) J Neurosci , vol.14 , pp. 7629-7640
    • Qin-Wei, Y.1    Johnson, J.2    Prevette, D.3    Oppenheim, R.W.4
  • 94
    • 0033615957 scopus 로고    scopus 로고
    • Programmed cell death of embryonic motoneurons triggered through the Fas death receptor
    • Raoul C, Henderson CE, Pettmann B (1999) Programmed cell death of embryonic motoneurons triggered through the Fas death receptor. J Cell Biol 147:1049-1062
    • (1999) J Cell Biol , vol.147 , pp. 1049-1062
    • Raoul, C.1    Henderson, C.E.2    Pettmann, B.3
  • 96
    • 0025321521 scopus 로고
    • Binding of brain-derived neurotrophic factor to the nerve growth factor receptor
    • Rodriguez-Tébar A, Dechant G, Barde Y-A (1990) Binding of brain-derived neurotrophic factor to the nerve growth factor receptor. Neuron 4:487-492
    • (1990) Neuron , vol.4 , pp. 487-492
    • Rodriguez-Tébar, A.1    Dechant, G.2    Barde, Y.-A.3
  • 97
    • 0033517190 scopus 로고    scopus 로고
    • NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling
    • Romashkova JA, Makarov SS (1999) NF-kappaB is a target of AKT in anti-apoptotic PDGF signalling. Nature 401:86-90
    • (1999) Nature , vol.401 , pp. 86-90
    • Romashkova, J.A.1    Makarov, S.S.2
  • 99
    • 0026597010 scopus 로고
    • Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis
    • Rothstein JD, Martin LJ, Kuncl RW (1992) Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis. N Engl J Med 326:1464-1468
    • (1992) N Engl J Med , vol.326 , pp. 1464-1468
    • Rothstein, J.D.1    Martin, L.J.2    Kuncl, R.W.3
  • 101
    • 0030698127 scopus 로고    scopus 로고
    • The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases
    • Roy N, Deveraux QL, Takahashi R, Salvesen GS, Reed JC (1997) The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases. EMBO J 16:6914-6925
    • (1997) EMBO J , vol.16 , pp. 6914-6925
    • Roy, N.1    Deveraux, Q.L.2    Takahashi, R.3    Salvesen, G.S.4    Reed, J.C.5
  • 102
    • 0028865136 scopus 로고
    • Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease
    • Sagot Y, Dubois Dauphin M, Tan SA, De Bilbao F, Aebischer P, Martinou J, Kato AC (1995) Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease. J Neurosci 15: 7727-7733
    • (1995) J Neurosci , vol.15 , pp. 7727-7733
    • Sagot, Y.1    Dubois Dauphin, M.2    Tan, S.A.3    De Bilbao, F.4    Aebischer, P.5    Martinou, J.6    Kato, A.C.7
  • 103
    • 0029950147 scopus 로고    scopus 로고
    • GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice
    • Sagot Y, Tan SA, Hammang JP, Aebischer P, Kato AC (1996) GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice. J Neurosci 16:2335-2341
    • (1996) J Neurosci , vol.16 , pp. 2335-2341
    • Sagot, Y.1    Tan, S.A.2    Hammang, J.P.3    Aebischer, P.4    Kato, A.C.5
  • 104
    • 0029925683 scopus 로고    scopus 로고
    • Intracellular signaling pathways activated by neurotrophic factors
    • Segal RA, Greenberg ME (1996) Intracellular signaling pathways activated by neurotrophic factors. Annu Rev Neurosci 19: 463-489
    • (1996) Annu Rev Neurosci , vol.19 , pp. 463-489
    • Segal, R.A.1    Greenberg, M.E.2
  • 106
    • 0032029605 scopus 로고    scopus 로고
    • Neurotrophic factors: Effects in modulating properties of the neuromuscular endplate
    • Sendtner M (1998) Neurotrophic factors: effects in modulating properties of the neuromuscular endplate. Cytokine Growth Factor Rev 9:1-7
    • (1998) Cytokine Growth Factor Rev , vol.9 , pp. 1-7
    • Sendtner, M.1
  • 108
    • 0027070473 scopus 로고
    • Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section
    • Sendtner M, Holtmann B, Kolbeck R, Thoenen H, Barde Y-A (1992a) Brain-derived neurotrophic factor prevents the death of motoneurons in newborn rats after nerve section. Nature 360:757-758
    • (1992) Nature , vol.360 , pp. 757-758
    • Sendtner, M.1    Holtmann, B.2    Kolbeck, R.3    Thoenen, H.4    Barde, Y.-A.5
  • 109
    • 0026749255 scopus 로고
    • Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy
    • Sendtner M, Schmalbruch H, Stöckli KA, Carroll P, Kreutzberg GW, Thoenen H (1992b) Ciliary neurotrophic factor prevents degeneration of motor neurons in mouse mutant progressive motor neuronopathy. Nature 358:502-504
    • (1992) Nature , vol.358 , pp. 502-504
    • Sendtner, M.1    Schmalbruch, H.2    Stöckli, K.A.3    Carroll, P.4    Kreutzberg, G.W.5    Thoenen, H.6
  • 113
    • 0029658491 scopus 로고    scopus 로고
    • Differential Ca2+ signaling induced by activation of the epidermal growth factor and nerve growth factor receptors
    • Tinhofer I, Maly K, Dietl P, Hochholdinger F, Mayr S, Obermeier A, Grunicke HH (1996) Differential Ca2+ signaling induced by activation of the epidermal growth factor and nerve growth factor receptors. J Biol Chem 271:30505-30509
    • (1996) J Biol Chem , vol.271 , pp. 30505-30509
    • Tinhofer, I.1    Maly, K.2    Dietl, P.3    Hochholdinger, F.4    Mayr, S.5    Obermeier, A.6    Grunicke, H.H.7
  • 114
    • 0026486878 scopus 로고
    • Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor
    • Traverse S, Gomez N, Paterson H, Marshall C, Cohen P (1992) Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor. Biochem J 288:351-355
    • (1992) Biochem J , vol.288 , pp. 351-355
    • Traverse, S.1    Gomez, N.2    Paterson, H.3    Marshall, C.4    Cohen, P.5
  • 115
    • 0029829495 scopus 로고    scopus 로고
    • Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice
    • [see comments] [retracted by Hagg T. In: Science 1999 Jul 16;285(5426):340]
    • Van der Zee CE, Ross GM, Riopelle RJ, Hagg T (1996) Survival of cholinergic forebrain neurons in developing p75NGFR-deficient mice [see comments] [retracted by Hagg T. In: Science 1999 Jul 16;285(5426):340]. Science 274:1729-1732
    • (1996) Science , vol.274 , pp. 1729-1732
    • Van Der Zee, C.E.1    Ross, G.M.2    Riopelle, R.J.3    Hagg, T.4
  • 116
    • 0028890986 scopus 로고
    • Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motoneurons in vivo
    • Vejsada R, Sagot Y, Kato AC (1995) Quantitative comparison of the transient rescue effects of neurotrophic factors on axotomized motoneurons in vivo. Eur J Neurosci 7:108-115
    • (1995) Eur J Neurosci , vol.7 , pp. 108-115
    • Vejsada, R.1    Sagot, Y.2    Kato, A.C.3
  • 117
    • 0020630328 scopus 로고
    • Both nerve growth factor and high K concentration support the survival of chick embryo sympathetic neurons
    • Wakade AR, Edgar D, Thoenen H (1983) Both nerve growth factor and high K concentration support the survival of chick embryo sympathetic neurons. Exp Cell Res 144:377-384
    • (1983) Exp Cell Res , vol.144 , pp. 377-384
    • Wakade, A.R.1    Edgar, D.2    Thoenen, H.3
  • 119
    • 0345498292 scopus 로고    scopus 로고
    • Bcl-2 targets the protein kinase Raf-1 to mitochondria
    • Wang HG, Rapp UR, Reed JC (1996) Bcl-2 targets the protein kinase Raf-1 to mitochondria. Cell 87:629-638
    • (1996) Cell , vol.87 , pp. 629-638
    • Wang, H.G.1    Rapp, U.R.2    Reed, J.C.3
  • 121
    • 0032589258 scopus 로고    scopus 로고
    • The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons
    • Wiese S, Metzger F, Holtmann B, Sendtner M (1999a) The role of p75NTR in modulating neurotrophin survival effects in developing motoneurons. Eur J Neurosci 11:1668-1676
    • (1999) Eur J Neurosci , vol.11 , pp. 1668-1676
    • Wiese, S.1    Metzger, F.2    Holtmann, B.3    Sendtner, M.4
  • 123
    • 0029885617 scopus 로고    scopus 로고
    • Differential regulation of Raf isozymes by growth versus differentiation inducing factors in PC12 pheochromocytoma cells
    • Wixler V, Smola U, Schuler M, Rapp U (1996) Differential regulation of Raf isozymes by growth versus differentiation inducing factors in PC12 pheochromocytoma cells. FEBS Lett 385: 131-137
    • (1996) FEBS Lett , vol.385 , pp. 131-137
    • Wixler, V.1    Smola, U.2    Schuler, M.3    Rapp, U.4
  • 124
    • 0028952568 scopus 로고
    • Interaction with TrkA immobilizes gp75 in the high affinity nerve growth factor receptor complex
    • Wolf DE, McKinnon CA, Daou MC, Stephens RM, Kaplan DR, Ross AH (1995) Interaction with TrkA immobilizes gp75 in the high affinity nerve growth factor receptor complex. J Biol Chem 270:2133-2138
    • (1995) J Biol Chem , vol.270 , pp. 2133-2138
    • Wolf, D.E.1    McKinnon, C.A.2    Daou, M.C.3    Stephens, R.M.4    Kaplan, D.R.5    Ross, A.H.6
  • 125
    • 0031046192 scopus 로고    scopus 로고
    • Hepatocyte growth factor promotes motor neuron survival and synergizes with ciliary neurotrophic factor
    • Wong V, Glass DJ, Arriga R, Yancopoulos GD, Lindsay RM, Conn G (1997) Hepatocyte growth factor promotes motor neuron survival and synergizes with ciliary neurotrophic factor. J Biol Chem 272:5187-5191
    • (1997) J Biol Chem , vol.272 , pp. 5187-5191
    • Wong, V.1    Glass, D.J.2    Arriga, R.3    Yancopoulos, G.D.4    Lindsay, R.M.5    Conn, G.6
  • 127
    • 0030865088 scopus 로고    scopus 로고
    • Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons
    • Yamamoto Y, Livet J, Polock R, Garces A, Arce V, deLapeyiére O, Henderson C (1997) Hepatocyte growth factor (HGF/SF) is a muscle-derived survival factor for a subpopulation of embryonic motoneurons. Development (Suppl) 124:2903-2913
    • (1997) Development (Suppl) , vol.124 , pp. 2903-2913
    • Yamamoto, Y.1    Livet, J.2    Polock, R.3    Garces, A.4    Arce, V.5    DeLapeyiére, O.6    Henderson, C.7
  • 128
    • 0030610047 scopus 로고    scopus 로고
    • Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation
    • Yeo TT, Chua-Couzens J, Butcher LL, Bredesen DE, Cooper JD, Valletta JS, Mobley WC, Longo FM (1997) Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation. J Neurosci 17:7594-7605
    • (1997) J Neurosci , vol.17 , pp. 7594-7605
    • Yeo, T.T.1    Chua-Couzens, J.2    Butcher, L.L.3    Bredesen, D.E.4    Cooper, J.D.5    Valletta, J.S.6    Mobley, W.C.7    Longo, F.M.8
  • 129
    • 0032499282 scopus 로고    scopus 로고
    • Rap1 mediates sustained MAP kinase activation induced by nerve growth factor [see comments]
    • York RD, Yao H, Dillon T, Ellig CL, Eckert SP, McCleskey EW, Stork PJ (1998) Rap1 mediates sustained MAP kinase activation induced by nerve growth factor [see comments]. Nature 392:622-626
    • (1998) Nature , vol.392 , pp. 622-626
    • York, R.D.1    Yao, H.2    Dillon, T.3    Ellig, C.L.4    Eckert, S.P.5    McCleskey, E.W.6    Stork, P.J.7
  • 130
    • 0028597994 scopus 로고
    • Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones
    • Zurn AD, Baetge EE, Hammang JP, Tan SA, Aebischer P (1994) Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones. Neuroreport 6:113-118
    • (1994) Neuroreport , vol.6 , pp. 113-118
    • Zurn, A.D.1    Baetge, E.E.2    Hammang, J.P.3    Tan, S.A.4    Aebischer, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.