Characterization of a Goα mutant that binds xanthine nucleotides

Journal of Biological Chemistry

Volumn 272, Issue 29, 1997, Pages 18015-18019

  Yu, Bo ^a   Slepak, Vladlen Z ^a,b   Simon, Melvin I ^a  

^a CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ASPARTIC ACID; NUCLEOTIDE; XANTHINE DERIVATIVE; BORDETELLA VIRULENCE FACTOR; GUANINE NUCLEOTIDE; GUANINE NUCLEOTIDE BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE; OLIGODEOXYRIBONUCLEOTIDE; RECOMBINANT PROTEIN; RIBONUCLEOTIDE; XANTHOSINE 5' TRIPHOSPHATE; XANTHOSINE 5'-TRIPHOSPHATE;

ARTICLE; BINDING AFFINITY; CELL MEMBRANE PERMEABILITY; CRYSTAL STRUCTURE; EFFECTOR CELL; GENE MUTATION; GENE STRUCTURE; GENETIC TRANSDUCTION; GENETIC TRANSFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN SYNTHESIS INHIBITION; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CELL STRAIN COS1; CHEMISTRY; ENZYME SPECIFICITY; KINETICS; MACROMOLECULE; METABOLISM; MOUSE; POINT MUTATION; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; COS CELLS; GTP-BINDING PROTEINS; GUANINE NUCLEOTIDES; KINETICS; MACROMOLECULAR SUBSTANCES; MICE; MUTAGENESIS, SITE-DIRECTED; NAD; OLIGODEOXYRIBONUCLEOTIDES; POINT MUTATION; RECOMBINANT PROTEINS; RIBONUCLEOTIDES; SUBSTRATE SPECIFICITY; TRANSFECTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0030610571     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.29.18015     Document Type: Article

References (44)

1. Neer, E. J. (1995) Cell 80, 249-257
2. Simon, M. I., Strathman, M. P., and Gautam, N. (1991) Science 252, 802-808
3. Gilman, A. G. (1987) Annu Rev. Biochem. 56, 615-649
4. Grand, R. J. A., Turnell, A. S., and Grabham, P. W. (1996) Biochem. J. 313, 353-368
5. Henderson, J. F., and Paterson, A. R. P. (1973) in Nucleotide Metabolism, p. 97-169, Academic Press, New York
6. Bourne, H. R., Sanders, D. A. and McCormick, F. (1990) Nature 348, 125-132
7. Bourne, H. R., Sanders, D. A., and McCormick, F. (1991) Nature 366, 654-663
8. Noel, J., Hamm, H. E., and Sigler, P. B. (1993) Nature 366, 654-663
9. Lambright, D. G., Noel, J. P., Hamm, H. E., and Sigler, P. B. (1994) Nature 369, 621-628
10. Sondek, J., Lambright, D. G., Noel, J. P., Hamm, H. E., and Sigler, P. B. (1994) Nature 372, 276-279
11. Coleman, D. E., Berghuis, A. M., Lee, E., Linder, M. E., Gilman, A. G., and Sprang, S. R. (1994) Science 265, 1405-1412
12. De Vos, A. M., Tong, L., Milburn, M. V., Maniatis, P. M., Jancarik, J., Noguchi, S., Nishimura, S., Muira, K., Ohtsuka, E., and Kim, S.-H. (1988) Science 239, 888-893
13. Jurnak, F. (1988) Science 230, 32-36
14. La Cour, T. F. M., Nyborg, J., Thirup, S., and Clark, B. F. C. (1985) EMBO J. 4, 2385-2388
15. Der, C. J., Pan, B.-T., and Cooper, G. M. (1986) Mol. Cell. Biol. 6, 3291-3294
16. Feig, A. L., Pan, B.-T., Roberts, T. M., and Cooper, G. M. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 4607-4611
17. Hwang, Y. W., and Miller, D. L. (1987) J. Biol. Chem. 262, 13081-13085
18. Weijland, A., and Parmeggiani, A. (1993) Science 259, 1311-1314
19. Jones, S., Litt, R. J., Richardson, C. J., and Seger, N. (1995) J. Cell Biol. 130, 1051-1061
20. Rybin, V., Ullrich, O., Rubino, M., Alexandrov, K., Simon, I., Seabra, M., Goody, R., and Zerial, M. (1996) Nature 383, 266-269
21. Hoffenberg, S., Nikolova, L., Pan, J. Y., Daniel, D. S., Wessling-Resnick, M., Knoll, B. J., and Dickey, B. F. (1995) Biochem. Biophys. Res. Commun. 215, 241-249
22. Powers, T., and Wolter, P. (1995) Science 269, 1422-1424
23. Kang, C., Sun, N., Honzatko, R. B., and Fromm, H. J. (1994) J. Biol. Chem. 269, 24046-24049
24. Slepak, V. Z., Wilkie, T. M., and Simon, M. I. (1993) J. Biol. Chem. 268, 1414-1423
25. Goody, R. S., Eckstein, F., and Schrimer, H. (1972) Biochim. Biophys. Acta 276, 155-161
26. Wu, D., Lee, C. H., Rhee, S. G., and Simon, M. I. (1992) J. Biol. Chem. 267, 1811-1817
27. Wu, D., Katz, A., Lee, C. H., and Simon, M. I. (1992) J. Biol. Chem. 267, 25798-25802
28. Higashijima, T., Ferguson, K. M., Sternweis, P. C., Smigel, M. D., and Gilman, A. G. (1987) J. Biol. Chem. 262, 762-766
29. Higashijima, T., Ferguson, K. M., Sternweis, P. C., Ross, E. M., Smigel, M. D., and Gilman, A. G. (1987) J. Biol. Chem. 262, 752-756
30. Hurley, J. B., Simon, M. I., Teplow, D. B., Robishaw, J. D., and Gilman, A. G. (1984) Science 226, 860-862
31. Graziano, M. P., and Gilman, A. G. (1989) J. Biol. Chem. 264, 15475-15482
32. Denker, B. M., Neer, E. J., and Schmidt, C. J. (1992) J. Biol. Chem. 267, 6272-6277
33. Bokoch, G. M., Katada, T., Northup, J. K., Hewlett, E. L., and Gilman, A. G. (1983) J. Biol. Chem. 258, 2072-2075
34. Casey, P. J., Graziano, M. P., and Gilman, A. G. (1989) Biochemistry 28, 611-616
35. Slepak, V. Z., Katz, A., and Simon, M. I. (1994) J. Biol. Chem. 270, 4037-4041
36. Ahnert-Hilger, G., Mach, W., Fohr, K. J., Gratzl, M. (1989) Methods Cell Biol. 31, 63-90
37. Zhong, J.-M., Chen-Hwang, M.-C., Hwang, Y.-W. (1995) J. Biol. Chem. 270, 10002-10007
38. Kleuss, C., Hescheler, J., Ewel, C., Rosenthal, W., Schultz, G., and Wittig, B. (1991) Nature 353, 43-48
39. Taussig, R., Sanchez, S., Rifo, M., Gilman, A. G., and Belardetti, F. (1992) Neuron 8, 799-809
40. Lledo, P. M., Homburger, V., Bockaert, J., and Vincent, J.-D. (1992) Neuron 8, 455-463
41. Kalkbrenner, F., Degtiar, V. E., Schenker, M., Brendel, S., Zobel, A., Heschler, J., Wittig, B., and Schultz, G. (1995) EMBO J. 14, 4728-4737
42. Charpentier, N., Prezeau, L., Carrette, J., Bertorelli, R., Le Cam, G., Manzoni, O., Bockaert, J., and Homburger, V. (1993) J. Biol. Chem. 268, 8980-8989
43. Ikeda, S. R. (1996) Nature 380, 255-258
44. Denker, B. M., Neer, E. J., and Schmidt, C. J. (1992) J. Biol. Chem. 267, 6272-6277