Proximity and orientation underlie signaling by the non-receptor tyrosine kinase ZAP70

EMBO Journal

Volumn 16, Issue 18, 1997, Pages 5618-5628

  Graef, Isabella A ^b   Holsinger, Leslie J ^b   Diver, Steve ^a   Schreiber, Stuart L ^a   Crabtree, Gerald R ^b  

^a HARVARD UNIVERSITY   (United States)

^b STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Kinase; Proximity; Signaling; Synthetic ligands; ZAP70

Indexed keywords

CALCINEURIN; CALCIUM ION; CD3 ANTIGEN; CELL MEMBRANE PROTEIN; HYBRID PROTEIN; LYMPHOCYTE ANTIGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE; RAS PROTEIN; T LYMPHOCYTE RECEPTOR;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME CONFORMATION; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; LIGAND BINDING; MEMBRANE PERMEABILITY; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPATIAL ORIENTATION;

ANIMALS; BINDING SITES; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE; DNA-BINDING PROTEINS; GENES, REPORTER; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KINETICS; MICE; PEPTIDYLPROLYL ISOMERASE; POLYMERASE CHAIN REACTION; PROTEIN-TYROSINE KINASES; RECEPTORS, ANTIGEN, T-CELL; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES; TACROLIMUS; TACROLIMUS BINDING PROTEINS; TRANSFECTION; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 0030863780     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/16.18.5618     Document Type: Article

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