Engineering of the myosin-Iβ nucleotide-binding pocket to create selective sensitivity to N6-modified ADP analogs

Journal of Biological Chemistry

Volumn 274, Issue 44, 1999, Pages 31373-31381

  Gillespie, Peter G ^a,b,e   Gillespie, Susan K H ^a,e   Mercer, John A ^c   Shah, Kavita ^d   Shokat, Kevan M ^d,f  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c MCLAUGHLIN RESEARCH INSTITUTE   (United States)

^d PRINCETON UNIVERSITY   (United States)

^e OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; GLYCINE; MYOSIN; TYROSINE; ADENOSINE TRIPHOSPHATASE; DRUG DERIVATIVE; ISOENZYME; N(6) (2 METHYLBUTYL)ADENOSINE DIPHOSPHATE; N(6)-(2-METHYLBUTYL)ADENOSINE DIPHOSPHATE;

ACTIN FILAMENT; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MOTILITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; ENZYME STRUCTURE; GENETIC ENGINEERING; INSECT; MISSENSE MUTATION; NONHUMAN; PRIORITY JOURNAL; AMINO ACID SEQUENCE; ANIMAL; BINDING SITE; CHEMICAL STRUCTURE; CHICKEN; DICTYOSTELIUM; DRUG ANTAGONISM; GENETICS; HYDROLYSIS; METABOLISM; MOLECULAR GENETICS; MOVEMENT (PHYSIOLOGY); MUTATION; PROTEIN BINDING; PROTEIN ENGINEERING; RAT;

ACTINS; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATASES; ADENOSINE TRIPHOSPHATE; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CHICKENS; DICTYOSTELIUM; HYDROLYSIS; ISOENZYMES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MOVEMENT; MUTATION; MUTATION, MISSENSE; MYOSINS; PROTEIN BINDING; PROTEIN ENGINEERING; RATS;

EID: 0033615354     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.44.31373     Document Type: Article

References (64)

1. Spudich, J. A. (1994) Nature 372, 515-518
2. Mooseker, M. S., and Cheney, R. E. (1995) Annu. Rev. Cell Dev. Biol. 11, 633-675
3. Hasson, T., Skowron, J. F., Gilbert, D. J., Avraham, K. B., Perry, W. L., and Bement, W. M. (1996) Genomics 36, 431-439
4. Probst, F. J., Fridell, R. A., Raphael, Y., Saunders, T. L., Wang, A., Liang, Y., Morell, R. J., Touchman, J. W., Lyons, R. H., Noben-Trauth, K., Friedman, T. B., and Camper, S. A. (1998) Science 280, 1444-1447
5. Bement, W. M., Hasson, T., Wirth, J. A., Cheney, R. E., and Mooseker, M. S. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 6549-6553
6. Solc, C. K., Derfler, B. H., Duyk, G. M., and Corey, D. P. (1994) Auditory Neuroscience 1, 63-75
7. Doberstein, S. K., Baines, I. C., Wiegand, G., Korn, E. D., and Pollard, T. D. (1993) Nature 365, 841-843
8. Wang, F. S., Wolenski, J. S., Cheney, R. E., Mooseker, M. S., and Jay, D. G. (1996) Science 273, 660-663
9. Hasson, T., Gillespie, P. G., Garcia, J. A., MacDonald, R. B., Zhao, Y., Yee, A. G., and Corey, D. P. (1997) J. Cell Biol. 137, 1287-1307
10. Gillespie, P. G., Wagner, M. C., and Hudspeth, A. J. (1993) Neuron 11, 581-594
11. Gibson, F., Walsh, J., Mburu, P., Varela, A., Brown, K. A., Antonio, M., Beisel, K. W., Steel, K. P., and Brown, S. D. M. (1995) Nature 374, 62-64
12. Avraham, K. B., Hasson, T., Steel, K. P., Kingsley, D. M., and Russell, L. B. (1995) Nat. Genet. 11, 369-375
13. Sweeney, H. L., and Holzbaur, E. L. (1996) Annu. Rev. Physiol 58, 751-792
14. Mercer, J. A., Seperack, P. K., Strobel, M. C., Copeland, N. G., and Jenkins, N. A. (1991) Nature 349, 709-713
15. Novak, K. D., Peterson, M. D., Reedy, M. C., and Titus, M. A. (1995) J. Cell Biol. 131, 1205-1221
16. De Lozanne, A., and Spudich, J. A. (1987) Science 236, 1086-1091
17. Weijland, A., and Parmeggiani, A. (1993) Science 269, 1311-1314
18. Weijland, A., Parlato, G., and Parmeggiani, A. (1994) Biochemistry 33, 10711-10717
19. Hwang, Y. W., and Miller, D. L. (1987) J. Biol. Chem. 262, 13081-13085
20. Jones, S., Litt, R. J., Richardson, C. J., and Segev, N. (1995) J. Cell Biol. 130, 1051-1061
21. Rybin, V., Ullrich, O., Rubino, M., Alexandrov, K., Simon, I., Seabra, C., and Goody. (1996) Nature 383, 266-269
22. Hoffenberg, S., Nikolova, L., Pan, J. Y., Daniel, D. S., Wessling-Resnick, M., Knoll, B. J., and Dickey, B. F. (1995) Biochem. Biophys. Res. Commun. 215, 241-249
23. Kang, C., Sun, N., Honzatko, R. B., and Fromm, H. J. (1994) J. Biol. Chem. 269, 24046-24049
24. Powers, T., and Walter, P. (1995) Science 269, 1422-1424
25. Shah, K., Liu, Y., Deirmengian, C., and Shokat, K. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 3565-3570
26. Liu, Y., Shah, K., Yang, F., Witucki, L., and Shokat, K. M. (1998) Chem. Biol. 5, 91-101
27. Bishop, A. C., Shah, K., Liu, Y., Witucki, L., Kung, C., and Shokat, K. M. (1998) Curr. Biol. 8, 257-266
28. Gillespie, P. G., and Corey, D. P. (1997) Neuron 19, 955-958
29. Kikugawa, K., Iizuka, K., and Ichino, M. (1973) J. Med. Chem. 16, 358-364
30. Ruppert, C., Godel, J., Muller, R. T., Kroschewski, R., Reinhard, J., and Bahler, M. (1995) J. Cell Sci. 108, 3775-3786
31. Deng, W. P., and Nickoloff, J. A. (1992) Anal. Biochem. 200, 81-88
32. O'Reilly, D. R., Miller, L. K., and Luckow, V. A. (1994) Baculovirus Expression Vectors: A laboratory Manual, Oxford University Press, New York
33. Pardee, J. D., and Spudich, J. A. (1982) Methods Enzymol. 85, 164-181
34. Gopalakrishna, R., and Anderson, W. B. (1982) Biochem. Biophys. Res. Commun. 104, 830-836
35. Wallace, R. W., Tallant, E. A., and Cheung, W. Y. (1983) Methods Enzymol. 102, 39-47
36. Coluccio, L. M. (1994) J. Cell Sci. 107, 2279-2284
37. Gill, S. C., and von Hippel, P. H. (1989) Anal. Biochem. 182, 319-326
38. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
39. Smith, P. K., Krohn, R. I., Hermanson, G. T., Mallia, A. K., Gartner, F. H., Provenzano, M. D., Fujimoto, E. K., Goeke, N. M., Olson, B. J., and Klenk, D. C. (1985) Anal. Biochem. 150, 76-85
40. Pollard, T. D., and Korn, E. D. (1973) J. Biol. Chem. 248, 4682-4690
41. Kron, S. J., and Spudich, J. A. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 6272-6276
42. Winkelmann, D. A., Bourdieu, L., Ott, A., Kinose, F., and Libchaber, A. (1995) Biophys. J. 68, 2444-2453
43. Post, P. L., Bokoch, G. M., and Mooseker, M. S. (1998) J. Cell Sci. 111, 941-950
44. Smith, C. A., and Rayment, I. (1996) Biochemistry 35, 5404-5417
45. Gulick, A. M., Bauer, C. B., Thoden, J. B., and Rayment, I. (1997) Biochemistry 36, 11619-11628
46. Fisher, A. J., Smith, C. A., Thoden, J. B., Smith, R., Sutoh, K., Holden, H. M., and Rayment, I. (1995) Biochemistry 34, 8960-8972
47. Bauer, C. B., Kuhlman, P. A., Bagshaw, C. R., and Rayment, I. (1997) J. Mol. Biol. 274, 394-407
48. Cope, M. J. T. V., Whisstock, J., Rayment, I., and Kendrick-Jones, J. (1996) Structure 969-987
49. Albanesi, J. P., Fujisaki, H., Hammer, J. A., III, Korn, E. D., Jones, R., and Sheetz, M. P. (1985) J. Biol. Chem. 260, 8649-8652
50. Ostap, E. M., and Pollard, T. D. (1996) J. Cell Biol. 132, 1053-1060
51. Tonomura, Y., Imamura, K., Ikehara, M., Uno, H., and Harada, F. (1967) J. Biochem. 61, 460-472
52. Wang, D., Pate, E., Cooke, R., and Yount, R. (1993) J. Muscle Res. Cell Motil. 14, 484-497
53. Pate, E., Nakamaye, K. L., Franks-Skiba, K., Yount, R. G., and Cooke, R. (1991) Biophys. J. 59, 598-605
54. Jontes, J. D., Milligan, R. A., Pollard, T. D., and Ostap, E. M. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 14332-14337
55. Zhu, T., Sata, M., and Ikebe, M. (1996) Biochemistry 35, 513-522
56. Howard, J. (1997) Nature 389, 561-567
57. Nishizaka, T., Miyata, H., Yoshikawa, H., Ishiwata, S., and Kinosita, K., Jr. (1995) Nature 377, 251-254
58. Huxley, A. F., and Simmons, R. M. (1971) Nature 233, 533-538
59. Cande, W. Z. (1986) Methods Enzymol. 134, 473-477
60. Gillespie, P. G., and Hudspeth, A. J. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 2710-2714
61. Assad, J. A., and Corey, D. P. (1992) J. Neurosci. 12, 3291-3309
62. Warrick, H. M., De Lozanne, A., Leinwand, L. A., and Spudich, J. A. (1986) Proc. Natl. Acad. Sci. U. S. A. 83, 9433-9437
63. Kinose, F., Wang, S. X., Kidambi, U. S., Moncman, C. L., and Winkelmann, D. A. (1996) J. Cell Biol. 134, 895-909
64. Kapoor, T. M., and Mitchison, T. J. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 9106-9111