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Volumn 21, Issue 8, 2000, Pages 371-378

Natural and designer binding sites made by phage display technology

Author keywords

[No Author keywords available]

Indexed keywords

DECAY ACCELERATING FACTOR; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; MONOCLONAL ANTIBODY; OLIGONUCLEOTIDE; TRANSFORMING GROWTH FACTOR BETA2; TUMOR NECROSIS FACTOR ALPHA;

EID: 0033853776     PISSN: 01675699     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0167-5699(00)01667-4     Document Type: Review
Times cited : (198)

References (80)
  • 3
    • 0022558297 scopus 로고
    • Replacing the complementarity-determining regions in a human antibody with those from a mouse
    • (1986) Nature , vol.321 , pp. 522-525
    • Jones, P.T.1
  • 5
    • 0021818675 scopus 로고
    • Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
    • (1985) Science , vol.228 , pp. 1315-1317
    • Smith, G.R.1
  • 7
    • 0024561993 scopus 로고
    • Direct cDNA cloning of the rearranged immunoglobulin variable region
    • (1989) Biotechniques , vol.7 , pp. 360-366
    • Chiang, Y.L.1
  • 8
    • 0024461313 scopus 로고
    • Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli
    • (1989) Nature , vol.341 , pp. 544-546
    • Ward, E.S.1
  • 9
    • 0024833055 scopus 로고
    • Generation of a large combinatorial library of the immunoglobulin repertoire in phage lambda
    • (1989) Science , vol.246 , pp. 1275-1281
    • Huse, W.D.1
  • 10
    • 0023922661 scopus 로고
    • Escherichia coli secretion of an active chimeric antibody fragment
    • (1988) Science , vol.240 , pp. 1041-1043
    • Better, M.1
  • 12
    • 0025226085 scopus 로고
    • Phage antibodies: Filamentous phage displaying antibody variable domains
    • (1990) Nature , vol.348 , pp. 552-554
    • McCafferty, J.1
  • 13
    • 0025740577 scopus 로고
    • Multi-subunit proteins on the surface of filamentous phage: Methodologies for displaying antibody (Fab) heavy and light chains
    • (1991) Nucleic Acids Rca. , vol.19 , pp. 4133-4137
    • Hoogenboom, H.R.1
  • 14
  • 15
    • 0025718897 scopus 로고
    • Expression of antibody Fab domains on bacteriophage surfaces
    • (1991) J. Immunology , vol.147 , pp. 3610-3614
    • Chang, C.N.1
  • 16
    • 0029757498 scopus 로고    scopus 로고
    • Phage diabody repertoires for selection of large numbers of bispecific antibody fragments
    • (1996) Nat. Biotechnol , vol.14 , pp. 1149-1154
    • McGuinness, B.T.1
  • 17
    • 0025835310 scopus 로고
    • Making antibody fragments using phage display libraries
    • (1991) Nature , vol.352 , pp. 624-628
    • Clackson, T.1
  • 19
    • 0025838698 scopus 로고
    • A large array of human monoclonal antibodies to type 1 human immunodeficiency virus from combinatorial libraries of asymptomatic individuals
    • (1991) Proc. Natl. Acad. Sci. U. S. A. , vol.88 , pp. 10134-10137
    • Burton, D.R.1
  • 20
    • 0031568670 scopus 로고    scopus 로고
    • Human anti-nicotinic acetylcholine receptor recombinant Fab fragments isolated from thymus-derived phage display libraries from myasthenia gravis patients reflect predominant specificities in serum and block the action of pathogenic serum
    • (1997) J. Immunol. , vol.158 , pp. 1919-1929
    • Graus, Y.F.1
  • 21
    • 0029021085 scopus 로고
    • Anti-melanoma antibodies from melanoma patients immunised with genetically modified autologous tumor cells: Selection of specific antibodies from single-chain Fv fusion phage libraries
    • (1995) Proc. Natl. Acad. Sci. U. S. A. , vol.92 , pp. 6537-6541
    • Cai, X.1    Garen, A.2
  • 22
    • 0026317443 scopus 로고
    • By-passing immunization: Human antibodies from V-gene libraries displayed on phage
    • (1991) J. Mol. Biol. , vol.221 , pp. 581-597
    • Marks, J.D.1
  • 28
    • 0031012062 scopus 로고    scopus 로고
    • Display of heterologous proteins on the surface of microorganisms: From the screening of combinatorial libraries to live recombinant vaccines
    • (1997) Nat. Biotechnol. , vol.15 , pp. 29-34
    • Georgiou, G.1
  • 31
    • 0033603596 scopus 로고    scopus 로고
    • A large non-immunized human Fab fragment phage library that permits rapid isolation and kinetic analysis of high affinity antibodies
    • (1999) J. Biol. Chem. , vol.274 , pp. 18218-18230
    • de Haard, H.J.1
  • 32
    • 0033406045 scopus 로고    scopus 로고
    • Selection of phage-displayed Fab antibodies on the active conformation of Ras yields a high affinity conformation-specific antibody preventing the binding of c-Raf kinase to Ras
    • (1999) FEBS Lett. , vol.463 , pp. 115-120
    • Horn, I.R.1
  • 35
    • 0033559241 scopus 로고    scopus 로고
    • Selection-dominant and nonaccessible epitopes on cell-surface receptors revealed by cell-panning with a large phage antibody library
    • (1999) Eur. J. Biochem. , vol.260 , pp. 774-784
    • Hoogenboom, H.R.1
  • 36
    • 0344813702 scopus 로고    scopus 로고
    • Antibody scFv fragments without disulfide bonds made by molecular evolution
    • (1998) J. Mol. Biol. , vol.275 , pp. 245-253
    • Proba, K.1
  • 38
    • 0030847726 scopus 로고    scopus 로고
    • Rescue of a neutralizing anti-viral antibody fragment from an intracellular polyclonal repertoire expressed in mammalian cells
    • (1997) FEBS Lett. , vol.414 , pp. 537-540
    • Gargano, N.1    Cattaneo, A.2
  • 41
    • 0033153570 scopus 로고    scopus 로고
    • Identification of a human anti-CD55 single-chain Fv by subtractive panning of a phage library using tumor and nontumor cell lines
    • (1999) Cancer Res. , vol.59 , pp. 2718-2723
    • Ridgway, J.B.1
  • 42
    • 0033562573 scopus 로고    scopus 로고
    • Protein microarrays for gene expression and antibody screening
    • (1999) Anal. Biochem. , vol.270 , pp. 103-111
    • Lueking, A.1
  • 43
    • 0033576335 scopus 로고    scopus 로고
    • A post-genomics challenge: Learning to read patterns of protein expression
    • (1999) Nature , vol.402 , pp. 715-720
    • Abbott, A.1
  • 45
    • 13144261717 scopus 로고    scopus 로고
    • Efficient construction of a large nonimmune phage antibody library: The production of high-affinity human single-chain antibodies to protein antigens
    • (1998) Proc. Natl. Acad. Sci. U. S. A. , vol.95 , pp. 6157-6162
    • Sheets, M.D.1
  • 46
    • 9344223986 scopus 로고    scopus 로고
    • Human antibody with sub-nanomolar affinities isolated from a large non-immunized phage display library
    • (1996) Nat. Biotechnol. , vol.14 , pp. 309-314
    • Vaughan, T.P.1
  • 47
    • 0028291823 scopus 로고
    • Isolation of high affinity human antibodies directly from large synthetic repertoires
    • (1994) EMBO J. , vol.13 , pp. 3245-3260
    • Griffiths, A.D.1
  • 51
  • 53
    • 0030575802 scopus 로고    scopus 로고
    • Isolation of picomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
    • (1996) J. Mol. Biol. , vol.263 , pp. 551-567
    • Schier, R.1
  • 54
    • 0029564921 scopus 로고
    • CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range
    • (1995) J. Mol. Biol. , vol.254 , pp. 392-403
    • Yang, W.P.1
  • 55
    • 0029981792 scopus 로고    scopus 로고
    • Light chains shuffling of a high affinity antibody results in a drift in epitote recognition
    • (1996) Mol. Immunol. , vol.33 , pp. 47-56
    • Ohlin, N.1
  • 56
    • 0026673067 scopus 로고
    • By-passing immunisation. Human antibodies from synthetic repertoires of germline VH gene segments rearranged in vitro
    • (1992) J. Mol. Biol. , vol.227 , pp. 381-388
    • Hoogenboom, H.R.1    Winter, G.2
  • 57
    • 0028006072 scopus 로고
    • Antibody fragments from a 'single pot' phage display library as immunochemical reagents
    • (1994) EMBO J. , vol.13 , pp. 692-698
    • Nissim, A.1
  • 58
    • 0027212809 scopus 로고
    • Selection of an anti-IGF-1 Fab from a Fab phage library created by mutagenesis of multiple CDR loops
    • (1993) Gene , vol.128 , pp. 103-109
    • Garrard, L.J.1    Henner, D.J.2
  • 59
    • 0029150047 scopus 로고
    • Domain libraries: Synthetic diversity for de novo design of antibody V regions
    • (1995) Gene , vol.160 , pp. 269-272
    • Soderlind, E.1
  • 60
    • 0032555478 scopus 로고    scopus 로고
    • Design and use of a phage display library. Human antibodies with subnanomolar affinity against a marker of angiogenesis eluted from a two-dimensional gel
    • (1998) J. Biol. Chem. , vol.273 , pp. 21769-21776
    • Pini, A.1
  • 61
    • 0032581610 scopus 로고    scopus 로고
    • Exploiting sequence space: Shuffling in vivo formed complementary determining regions into a master framework
    • (1998) Gene , vol.215 , pp. 471-476
    • Jirholt, P.1
  • 62
    • 0344631762 scopus 로고    scopus 로고
    • Expanding the conformational diversity by random insertions to CDRH2 results in improved anti-estradiol antibodies
    • (1999) J. Mol. Biol. , vol.291 , pp. 589-602
    • Lamminmaki, U.1
  • 63
    • 0033593238 scopus 로고    scopus 로고
    • Towards the design of an antibody that recognises a given protein epitope
    • (1999) J. Mol. Biol. , vol.285 , pp. 909-915
    • Kirkham, P.M.1
  • 65
    • 0034635335 scopus 로고    scopus 로고
    • Fully synthetic human combinatorial antibody libraries (HuCAL) based on modular consensus frameworks and CDRs randomized with trinucleotides
    • (2000) J. Mol. Biol. , vol.296 , pp. 57-86
    • Knappik, A.1
  • 66
    • 0030767656 scopus 로고    scopus 로고
    • Selection and identification of single domain antibody fragments from camel heavy-chain antibodies
    • (1997) FEBS Lett. , vol.414 , pp. 521-526
    • Arbabi Ghahroudi, M.1
  • 67
    • 0029746203 scopus 로고    scopus 로고
    • Single antibody domains as small recognition units: Design and in vitro antigen selection of camelized, human VH domains with improved protein stability
    • (1996) Protein Eng. , vol.9 , pp. 531-537
    • Davies, J.1    Riechmann, L.2
  • 68
    • 0032763794 scopus 로고    scopus 로고
    • An antibody single-domain phage display library of a native heavy chain region: Isolation of functional single- domain VH molecules with a unique interface
    • (1999) J. Mol. Biol. , vol.290 , pp. 685-698
    • Reiter, Y.1
  • 70
    • 0032509129 scopus 로고    scopus 로고
    • The fobronection type III domain as a scaffold for novel binding proteins
    • (1998) J. Mol. Biol. , vol.284 , pp. 1141-1151
    • Koide, A.1
  • 71
    • 0034705696 scopus 로고    scopus 로고
    • Development and application of cytotoxic T lymphocyte-associated antigen 4 as a protein scaffold for the generation of novel binding ligands
    • (2000) FEBS Lett. , vol.475 , pp. 225-231
    • Hufton, S.E.1
  • 74
    • 0028141993 scopus 로고
    • Guiding the selection of human antibodies from phage display repetoires to single epitope of an antigen
    • (1994) Biotechnology , vol.12 , pp. 899-903
    • Jespers, L.S.1
  • 75
    • 9544250404 scopus 로고    scopus 로고
    • Clinical evidence of efficient tumor targeting based on single-chain Fv antibody selected from a combinatorial library
    • (1996) Nat. Med. , vol.2 , pp. 979-984
    • Begent, R.H.1
  • 76
    • 0030575802 scopus 로고    scopus 로고
    • Isolation of pricomolar affinity anti-c-erbB-2 single-chain Fv by molecular evolution of the complementarity determining regions in the center of the antibody binding site
    • (1996) J. Mol. Biol. , vol.263 , pp. 551-567
    • Schier, R.1
  • 77
    • 0032189703 scopus 로고    scopus 로고
    • Human single-chain Fv antibodies to MUC1 core peptide selected from phage display libraries recognize unique epitopes and predominantly bind adenocarcinoma
    • (1998) Cancer Res. , vol.58 , pp. 4324-4332
    • Henderikx, P.1
  • 78
    • 0032827243 scopus 로고    scopus 로고
    • Selective targeting and photocoagulation of ocular angiogenesis mediated by a phage-derived human antibody fragment
    • (1999) Nat. Biotechnol. , vol.17 , pp. 984-988
    • Birchler, N.1
  • 79
    • 0034711956 scopus 로고    scopus 로고
    • Guided selection of a pan carcimona specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent
    • (2000) J. Mol. Biol. , vol.296 , pp. 833-849
    • Beiboer, S.H.1
  • 80
    • 0030993418 scopus 로고    scopus 로고
    • Antibody humanization using monovalent phage display
    • (1997) J. Biol. Chem. , vol.272 , pp. 10678-10684
    • Baca, N.1


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