-
2
-
-
0026684815
-
Rapid tumour penetration of a single-chain Fv and comparison with other immunoglobulin forms
-
Yokota, T , Milenic, D.E., Whitlow, M. & Schlom, J. Rapid tumour penetration of a single-chain Fv and comparison with other immunoglobulin forms. Cancer Res 52, 3402-3408 (1992).
-
(1992)
Cancer Res
, vol.52
, pp. 3402-3408
-
-
Yokota, T.1
Milenic, D.E.2
Whitlow, M.3
Schlom, J.4
-
3
-
-
0004198722
-
Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli
-
Huston, J.S. et al. Protein engineering of antibody binding sites: Recovery of specific activity in an anti-digoxin single-chain Fv analogue produced in Escherichia coli. Proc. Natl. Acad. Sci. USA 85, 5879-5883 (1988).
-
(1988)
Proc. Natl. Acad. Sci. USA
, vol.85
, pp. 5879-5883
-
-
Huston, J.S.1
-
4
-
-
0025362523
-
In vivo tumor targeting of a recombinant single-chain antigen-binding protein
-
Colcher, D. et al. In vivo tumor targeting of a recombinant single-chain antigen-binding protein. J. Natl. Cancer Inst. 82, 1191-1197 (1990).
-
(1990)
J. Natl. Cancer Inst.
, vol.82
, pp. 1191-1197
-
-
Colcher, D.1
-
5
-
-
0026327378
-
Construction, binding properties, metabolism, and tumor targeting of a single chain Fv derived from the pancarcinoma monoclonal antibody CC49
-
Milenic, D.E. et al Construction, binding properties, metabolism, and tumor targeting of a single chain Fv derived from the pancarcinoma monoclonal antibody CC49. Cancer Res. 51, 6363-6371 (1991).
-
(1991)
Cancer Res.
, vol.51
, pp. 6363-6371
-
-
Milenic, D.E.1
-
6
-
-
0027454278
-
Construction, characterisation and kinetics of a single chain antibody recognising the tumour associated antigen placental alkaline phosphatase
-
Savage, P. et al. Construction, characterisation and kinetics of a single chain antibody recognising the tumour associated antigen placental alkaline phosphatase. Br. J. Cancer 68, 738-742 (1993).
-
(1993)
Br. J. Cancer
, vol.68
, pp. 738-742
-
-
Savage, P.1
-
7
-
-
0024833055
-
Generation of a large combinatorial library of the immunological repertoire in phage lambda
-
Huse, W.E. et al. Generation of a large combinatorial library of the immunological repertoire in phage lambda. Science 246, 1275-1281 (1989)
-
(1989)
Science
, vol.246
, pp. 1275-1281
-
-
Huse, W.E.1
-
8
-
-
0025226085
-
Phage antibodies: Filamentous phage displaying antibody variable domains
-
McCafferty, J., Griffiths, A.D., Winter, G. & Chiswell, D J. Phage antibodies: Filamentous phage displaying antibody variable domains. Nature 348, 552-554 (1990).
-
(1990)
Nature
, vol.348
, pp. 552-554
-
-
McCafferty, J.1
Griffiths, A.D.2
Winter, G.3
Chiswell, D.J.4
-
9
-
-
0025835310
-
Making antibody fragments using phage display libraries
-
Clackson, T., Hoogenboom, H.R., Griffiths, A.D. & Winter, G. Making antibody fragments using phage display libraries. Nature 352, 624-628 (1991).
-
(1991)
Nature
, vol.352
, pp. 624-628
-
-
Clackson, T.1
Hoogenboom, H.R.2
Griffiths, A.D.3
Winter, G.4
-
10
-
-
0026699293
-
Selection of phage antibodies by binding affinity: Mimicking affinity maturation
-
Hawkins, R.E., Russell, S.J. & Winter, G. Selection of phage antibodies by binding affinity: Mimicking affinity maturation. J. Mol. Biol. 226, 889-896 (1992).
-
(1992)
J. Mol. Biol.
, vol.226
, pp. 889-896
-
-
Hawkins, R.E.1
Russell, S.J.2
Winter, G.3
-
11
-
-
0028078866
-
Phage libraries for generation of clinically useful antibodies
-
Chester, K.A. et al. Phage libraries for generation of clinically useful antibodies. Lancet 343, 455-456 (1994).
-
(1994)
Lancet
, vol.343
, pp. 455-456
-
-
Chester, K.A.1
-
12
-
-
0028291823
-
Isolation of high affinity human antibodies directly from large synthetic repertoires
-
Griffiths, A D. et al Isolation of high affinity human antibodies directly from large synthetic repertoires. EMBO J. 13, 3245-3260 (1994).
-
(1994)
EMBO J.
, vol.13
, pp. 3245-3260
-
-
Griffiths, A.D.1
-
13
-
-
0028989908
-
A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma
-
Verhaar, M.J et al. A single chain Fv derived from a filamentous phage library has distinct tumour targeting advantages over one derived from a hybridoma. Int. J. Cancer 61, 497-501 (1995).
-
(1995)
Int. J. Cancer
, vol.61
, pp. 497-501
-
-
Verhaar, M.J.1
-
14
-
-
0028836167
-
Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography
-
Casey, J.L. et al. Purification of bacterially expressed single chain Fv antibodies for clinical applications using metal chelate chromatography. J Immunol. Methods 179, 105-116 (1995).
-
(1995)
J Immunol. Methods
, vol.179
, pp. 105-116
-
-
Casey, J.L.1
-
15
-
-
0022773783
-
Cancer Research Campaign operation manual for control of production, preclinical toxicology and phase I trials of anti tumour antibodies and drug antibody conjugates
-
Operation Manual
-
Operation Manual. Cancer Research Campaign operation manual for control of production, preclinical toxicology and phase I trials of anti tumour antibodies and drug antibody conjugates. Br. J. Cancer 54, 557-568 (1986).
-
(1986)
Br. J. Cancer
, vol.54
, pp. 557-568
-
-
-
16
-
-
0026419319
-
Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery
-
Houghten, R.A et al. Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery. Nature 354, 84-86 (1991).
-
(1991)
Nature
, vol.354
, pp. 84-86
-
-
Houghten, R.A.1
-
17
-
-
0025194307
-
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
-
Tuerk, C. & Gold, L. Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase Science 249, 505-510 (1990).
-
(1990)
Science
, vol.249
, pp. 505-510
-
-
Tuerk, C.1
Gold, L.2
-
18
-
-
0028278170
-
The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library
-
Bunin, B A , Plunkett, M.J. & Ellman, J A. The combinatorial synthesis and chemical and biological evaluation of a 1,4-benzodiazepine library. Proc. Natl. Acad. Sci. USA 91, 4708-4712 (1994).
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4708-4712
-
-
Bunin, B.A.1
Plunkett, M.J.2
Ellman, J.A.3
-
20
-
-
0027958916
-
2 antibodies
-
2 antibodies. Br. J. Cancer 70, 521-525 (1994).
-
(1994)
Br. J. Cancer
, vol.70
, pp. 521-525
-
-
Lane, D.M.1
-
21
-
-
0024416962
-
Antibody distribution and dosimetry in patients receiving radiolabelled antibody therapy for colorectal cancer
-
Begent, R.H.J. et al. Antibody distribution and dosimetry in patients receiving radiolabelled antibody therapy for colorectal cancer. Br. J. Cancer 60, 406-412 (1989).
-
(1989)
Br. J. Cancer
, vol.60
, pp. 406-412
-
-
Begent, R.H.J.1
-
22
-
-
0025148495
-
Disposition characteristics of macromolecules in tumour-bearing mice
-
Takakura, Y., Fujita, T , Hashido, M. & Sezoni, H. Disposition characteristics of macromolecules in tumour-bearing mice. Pharm. Res. 7, 339-346 (1990).
-
(1990)
Pharm. Res.
, vol.7
, pp. 339-346
-
-
Takakura, Y.1
Fujita, T.2
Hashido, M.3
Sezoni, H.4
-
23
-
-
18544410822
-
2::anti-CEA scFv fusion protein
-
2::anti-CEA scFv fusion protein. Immunotechnology 2, 47-57 (1996).
-
(1996)
Immunotechnology
, vol.2
, pp. 47-57
-
-
Michael, N.P.1
-
24
-
-
0002726158
-
Antibody directed enzyme prodrug therapy: Pilot scale clinical trial
-
Bagshawe, K.D., Sharma, S.K., Springer, C.S. & Antoniw, P Antibody directed enzyme prodrug therapy: Pilot scale clinical trial. Tumour Target 1, 17-29 (1995).
-
(1995)
Tumour Target
, vol.1
, pp. 17-29
-
-
Bagshawe, K.D.1
Sharma, S.K.2
Springer, C.S.3
Antoniw, P.4
-
25
-
-
0029564921
-
CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV antibody into the picomolar range
-
Yang, W-P et al. CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV antibody into the picomolar range. J. Mol. Biol. 254, 392-403 (1995).
-
(1995)
J. Mol. Biol.
, vol.254
, pp. 392-403
-
-
Yang, W.-P.1
-
26
-
-
0029111580
-
Synthetic human antibodies
-
Barbas, C.F. III. Synthetic human antibodies Nature Med 1, 837-839 (1995).
-
(1995)
Nature Med
, vol.1
, pp. 837-839
-
-
Barbas III, C.F.1
-
28
-
-
0028351657
-
Chemotherapy for colorectal cancer
-
Moertel, C.G. Chemotherapy for colorectal cancer. N. Engl. J. Med. 330, 1136-1142 (1994)
-
(1994)
N. Engl. J. Med.
, vol.330
, pp. 1136-1142
-
-
Moertel, C.G.1
-
29
-
-
4244039573
-
Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: A randomized trial
-
Glimelius, B. for the Nordic Gastrointestinal Tumour Adjuvant Therapy Group. Expectancy or primary chemotherapy in patients with advanced asymptomatic colorectal cancer: A randomized trial Eur J. Cancer S82 (Suppl. 2), 462 (1991).
-
(1991)
Eur J. Cancer
, vol.S82
, Issue.2 SUPPL.
, pp. 462
-
-
Glimelius, B.1
-
30
-
-
0030140040
-
99TTc radiolabelling using a phage-derived single chain Fv with C- terminal cysteine for colorectal tumour imaging
-
99TTc radiolabelling using a phage-derived single chain Fv with C- terminal cysteine for colorectal tumour imaging J. Nucl. Med. 37, 868-872 (1996).
-
(1996)
J. Nucl. Med.
, vol.37
, pp. 868-872
-
-
Verhaar, M.J.1
-
31
-
-
0027500724
-
Cancer Research Campaign operation manual for control recommendations for products derived from recombinant DNA technology prepared for investigational administration to patients with cancer in phase I trials
-
Begent, R.H.J et al. Cancer Research Campaign operation manual for control recommendations for products derived from recombinant DNA technology prepared for investigational administration to patients with cancer in phase I trials Eur. J. Cancer 29A, 1907-1910 (1993).
-
(1993)
Eur. J. Cancer
, vol.29 A
, pp. 1907-1910
-
-
Begent, R.H.J.1
-
32
-
-
34547383713
-
Preparation of iodine-131 labelled human growth hormone of high specific activity
-
Hunter, W.M. & Greenwood, F.C Preparation of iodine-131 labelled human growth hormone of high specific activity. Nature 194, 495-496 (1962).
-
(1962)
Nature
, vol.194
, pp. 495-496
-
-
Hunter, W.M.1
Greenwood, F.C.2
-
33
-
-
0025731301
-
A phase-I study of repeated therapy with radiolabelled antibody to carcinoembryonic antigen using intermittent or continuous administration of cyclosporin A to suppress the immune response
-
Ledermann, J.A et al. A phase-I study of repeated therapy with radiolabelled antibody to carcinoembryonic antigen using intermittent or continuous administration of cyclosporin A to suppress the immune response. Int. J. Cancer 47, 659-664 (1991).
-
(1991)
Int. J. Cancer
, vol.47
, pp. 659-664
-
-
Ledermann, J.A.1
|