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Volumn 15, Issue 6, 2000, Pages 557-569

The antifungal activity of sulfonylated/carboxylated derivatives of dibenzo-1,4-dioxine-2-acetyloxime may be due to inhibition of lanosterol-14α-demethylase

(3) Mastrolorenzo, A a Scozzafava, A a Supuran, C T a

a UNIVERSITY OF FLORENCE (Italy)

Author keywords

(Thio)carbamates; Antifungal compounds; Azole antifungals; Dibenzo 1,4 dioxine 2 acetyloxime; Ergosterol biosynthesis inhibitors; Lanosterol 14 demethylase; ; Sulfonylation

Indexed keywords

ANTIFUNGAL AGENT; CARBAMIC ACID DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; CYTOCHROME P450; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME 2 CARBOXYBENZENESULFONIC ACID; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME 2 NITROBENZENESULFONIC ACID; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME 3,4 DICHLOROPHENYLSULFONYLCARBAMIC ACID; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME 4 CHLOROBENZENESULFONYLCARBAMIC ACID; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME 4 CHLOROXYBENZENESULFONIC ACID; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME 4 METHOXYBENZENESULFONIC ACID; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME DERIVATIVE; DIBENZO 1,4 DIOXINE 2 ACETYLOXIME PENTAFLUOROCARBOXYLIC ACID; ENZYME INHIBITOR; ERGOSTEROL; ISOCYANIC ACID DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; ITRACONAZOLE; KETOCONAZOLE; O DEMETHYLASE; STEROL 14ALPHA DEMETHYLASE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTIFUNGAL ACTIVITY; ARTICLE; ASPERGILLUS; CANDIDA ALBICANS; CONTROLLED STUDY; DRUG POTENCY; DRUG PROTEIN BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STEROL SYNTHESIS;

ASPERGILLUS FLAVUS; CANDIDA ALBICANS;

EID: 0033746353 PISSN: 87555093 EISSN: None Source Type: Journal
DOI: 10.3109/14756360009040710 Document Type: Article

Times cited : (3)

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