Characterization and catalytic properties of the sterol 14α-demethylase from Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 16, 1999, Pages 8937-8942

  Bellamine, Aouatef ^a   Mangla, Anil T ^b   Nes, W David ^b   Waterman, Michael R ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b TEXAS TECH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOARTENOL; DNA; FERREDOXIN; FLAVODOXIN; FUNCTIONAL GROUP; LANOSTEROL; PYRROLE DERIVATIVE; STEROL 14ALPHA DEMETHYLASE; STEROL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; ENZYME ACTIVE SITE; ENZYME KINETICS; MOLECULAR WEIGHT; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SEQUENCE HOMOLOGY; STEREOCHEMISTRY; STEROL SYNTHESIS;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; KINETICS; MYCOBACTERIUM TUBERCULOSIS; OXIDOREDUCTASES; RATS; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY; SUBSTRATE SPECIFICITY;

ACTINOBACTERIA (CLASS); ANIMALIA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; MAMMALIA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROKARYOTA; UNCULTURED ACTINOMYCETE;

EID: 0033529797     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.16.8937     Document Type: Article

References (44)

1. Nes, W. R. & Nes, W. D. (1980) Lipids in Evolution (Plenum, New York).
2. Nes, W. D., Norton, R. A., Crumley, F. G., Madigan, S. J. & Katz, E. R. (1990) Proc. Natl. Acad. Sci. USA 87, 7565-7569.
3. Burrow, W., Moudler, J. W. & Lewert, R. M. (1966) Text Book of Microbiology (Sanders, Philadelphia), 18th Ed., p. 748.
4. Nes, W. R. (1974) Lipids 9, 596-612.
5. Ourisson, G., Rohmer, M. & Poralla, K. (1987) Annu. Rev. Microbiol. 42, 301-333.
6. Ramgopal, M. & Bloch, K. (1983) Proc. Natl. Acad. Sci. USA 80, 712-715.
7. Pinto, W. J., Lozano, R., Sekula, B. C. & Nes, W. R. (1983) Biochem. Biophys. Res. Commun. 112, 47-54.
8. Nes, W. D. (1987) ACS Symp. Ser. 325, 304-328.
9. Nes, W. D. (1990) Recent Adv. Phytochem. 24, 283-327.
10. Bird, C. W., Lynch, J. M., Pirt, F. J. & Reid, W. W. (1971) Nature (London) 230, 473-474.
11. Kohl, W., Gloe, A. & Reichembach, H. (1983) J. Gen. Microbiol. 129, 1629-1636.
12. Lois. L. M., Campos, N., Surya, R. P., Danielsen, K., Rohmer, M. & Boronat, A. (1998) Proc. Natl. Acad. Sci. USA 95, 2105-2110.
13. Takahashi, S., Kuzuyama, T., Watanabe, H. & Seto, H. (1998) Proc. Natl. Acad. Sci. USA 95, 9879-9884.
14. Lamb, D. C., Kelly, D. E., Manning, N. J. & Kelly, S. L. (1998) FEBS Lett. 437, 142-144.
15. Philipp, W., J., Poulet, S., Eiglmeier, K., Pascopella, L., Balasubramanian, V., Heym, B., Bergh, S., Bloom, B. R., Jacobs, W. R., Jr., & Cole, S. T. (1996) Proc. Natl. Acad. Sci. USA 93, 3132-3137.
16. Cole, S. T., Brosch, R., Parkhill, J., Garnier, T., Churcher, C., Harris, D., Gordon, S. V., Eiglmeier, K., Gas, S., Barry, C. E., III, et al. (1998) Nature (London) 393, 537-544.
17. Yoshida, Y., Noshiro, M., Aoyama, Y., Kawamoto, T., Horiuchi, T. & Gotoh, O. (1997) J. Biochem. (Tokyo) 122, 1122-1128.
18. Aoyama, Y., Horiuchi, T., Gotoh, O., Noshiro, M. & Yoshida, Y. (1998) J. Biochem. (Tokyo) 124, 694-696.
19. Jenkins, C. M. & Waterman, M. R. (1994) J. Biol. Chem. 269, 27401-27408.
20. Fischer, R. T., Stam, S. H., Johnson, P. R., Ko, S. S., Magolda, R. L., Gaylor, J. L. & Trzaskos, J. M. (1989) J. Lipid Res. 30, 1621-1632.
21. Pascal, R. A., Cheng, P. & Schroepfer, G. F. (1980) J. Am. Chem. Soc. 102, 6599-6601.
22. Venkatramesh, M. & Nes, W. D. (1995) Arch. Biochem. Biophys. 324, 189-199.
23. Rahier, A. & Taton, M. (1990) Biochem. Soc. Trans. 18, 52-56.
24. Yoshida, Y. & Aoyama, Y. (1991) Biochem. Soc. Trans. 19, 778-782.
25. Omura, T. & Sato, R. (1964) J. Biol. Chem. 239, 2379-2385.
26. Venkatramesh, M., Guo, D. A., Jia, Z. & Nes, W. D. (1996) Biochim. Biophys. Acta 1299, 313-324.
27. Nes, W. D., Janssen, G. G., Crumley, F. G., Kalinowska, M. & Akihisa, T. (1993) Arch. Biochem. Biophys. 300, 724-733.
28. O'Keefe, D. P., Gibson, K. J., Emptage, M. H., Lenstra, R., Romesser, J. A., Litle, P. J. & Omer, C. A. (1991) Biochemistry 30, 447-455.
29. Bauer, S. & Shiloach, J. (1974) Biotechnol. Bioeng. 16, 933-941.
30. Stromstedt, M., Rozman, D. & Waterman, M. R. (1996) Arch. Biochem. Biophys. 329, 73-81.
31. Xu, S. H., Norton, R. A., Crumley, F. G. & Nes, W. D. (1988) J. Chromatogr. 452, 377-398.
32. Nes, W. D., Koike, K., Jia, Z., Sakamoto, Y., Satou, T., Nikaido, T. & Griffin, J. F. (1998) J. Am. Chem. Soc. 120, 5970-5980.
33. Dale, J. W. & Patki, A. (1990) in Molecular Biology of the Mycobacteria, ed. McFadden, J. (Academic, San Diego), pp. 173-198.
34. Vermilion, J. L. & Coon, M. J. (1978) J. Biol. Chem. 253, 8812-8819.
35. Coghlan, V. M. & Vickery L. E. (1991) J. Biol. Chem. 266, 18606-18612.
36. Goad, L. J. & Akhisa, T. (1991) Analysis of Sterols (Blakie, New York).
37. Guengerich, F. P. (1983) Biochemistry 22, 2811-2820.
38. Yoshida, Y. & Aoyama, Y. (1987) Biochem. Pharmacol. 36, 229-235.
39. Salmon, F., Taton, M., Benveniste, P. & Rahier, A. (1992) Arch. Biochem. Biophys. 297, 123-131.
40. Gough, N. M. & Adams, J. M. (1978) Biochemistry 17, 5560-5566.
41. Shimada, T., Wunsch, R. M., Hanna, I., Sutter, T. R., Guengerich, F. P. & Gillam, E. M. J. (1998) Arch. Biochem. Biophys. 357, 111-120.
42. Nes, W. D., Janssen, G. G. & Bergenstrahle, A. (1991) J. Biol. Chem. 266, 15202-15212.
43. De Boer, H. A. & Hui, A. (1991) in Gene Expression Technology, ed. Goeddel, D. V. (Academic, San Diego), Vol. 185, pp. 103-114.
44. Fenton, M. J. & Vermeulen, M. W. (1996) Infect. Immunol. 64, 683-690.