Synthesis and nicotinic acetylcholine receptor in vivo binding properties of 2-fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine: A new positron emission tomography ligand for nicotinic receptors

Journal of Medicinal Chemistry

Volumn 42, Issue 12, 1999, Pages 2251-2259

  Dollé, Frédéric ^a   Dolci, Lilian ^a   Valette, Héric ^a   Hinnen, Françoise ^a   Vaufrey, Françoise ^a   Guenther, Ilonka ^a   Fuseau, Chantal ^a   Coulon, Christine ^a   Bottlaender, Michel ^a   Crouzel, Christian ^a  

^a DIF   (France)

Author keywords

[No Author keywords available]

Indexed keywords

2 FLUORO 3 [2 AZETIDINYLMETHOXY]PYRIDINE; 3 (2 AZETIDINYLMETHOXY)PYRIDINE; AZETIDINE DERIVATIVE; NICOTINIC RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG DISTRIBUTION; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; INTRAVENOUS DRUG ADMINISTRATION; LIGAND BINDING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; REACTION TIME;

ANIMALS; AZETIDINES; BRAIN; FLUORINE RADIOISOTOPES; HUMANS; LIGANDS; MALE; PAPIO; PYRIDINES; RADIOPHARMACEUTICALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0033578078     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9910223     Document Type: Article

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