Synthesis of a fluorine-18 labeled derivative of epibatidine for in vivo nicotinic acetylcholine receptor PET imaging

Bioorganic and Medicinal Chemistry

Volumn 7, Issue 3, 1999, Pages 467-479

  Dolci, Lilian ^a   Dolle, Frédéric ^a   Valette, Héric ^a   Vaufrey, Françoise ^a   Fuseau, Chantal ^a   Bottlaender, Michel ^a   Crouzel, Christian ^a  

^a DIF   (France)

Author keywords

Fluorine 18; Nicotinic acetylcholine receptor; Norchlorofluoroepibatidine; Positron emission tomography

Indexed keywords

ANALGESIC AGENT; EPIBATIDINE; FLUORINE 18; NICOTINIC RECEPTOR; NORCHLOROFLUOROEPIBATIDINE F 18; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BABOON; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; REACTION ANALYSIS; STEREOCHEMISTRY;

ANIMALS; BENZAMIDES; BICYCLO COMPOUNDS, HETEROCYCLIC; BRAIN; FLUORINE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MICROWAVES; NICOTINIC AGONISTS; PAPIO; RECEPTORS, NICOTINIC; STEREOISOMERISM; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0033018596     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(98)00261-2     Document Type: Article

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