Synthesis and nicotinic acetylcholine receptor binding properties of exo-2-(2'-fluoro-5'-pyridinyl)-7-azabicyclo-[2.2.1]heptane: A new positron emission tomography ligand for nicotinic receptors

Journal of Medicinal Chemistry

Volumn 40, Issue 15, 1997, Pages 2293-2295

  Liang, F ^a   Navarro, H A ^a   Abraham, P ^a   Kotian, P ^a   Ding, Y S ^a   Fowler, J ^a   Volkow, N ^a   Kuhar, M J ^a   Carroll, F I ^a  

^a RTI INTERNATIONAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 (TERT BUTYLOXYCARBONYL) 2 [2' (N,N,N TRIMETHYLAMMONIUMYL) 5' PYRIDINYL] 7 AZABICYCLO[2.2.1]HEPTANE IODIDE; EPIBATIDINE; FLUORINE 18; FLUORINE DERIVATIVE; LIGAND; NICOTINE; NICOTINIC RECEPTOR; NORCHLOROFLUOROEPIBATIDINE; UNCLASSIFIED DRUG;

ANALGESIA; ARTICLE; CHEMICAL STRUCTURE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; POSITRON EMISSION TOMOGRAPHY;

ANIMALS; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING, COMPETITIVE; BRAIN; MICE; NICOTINIC ANTAGONISTS; PAPIO; PYRIDINES; RADIOLIGAND ASSAY; RECEPTORS, NICOTINIC; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0030759242     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm970187d     Document Type: Article

References (28)