Synthesis of [18F]norchlorofluoroepibatidine and its N-methyl derivative: New PET ligands for mapping nicotinic acetylcholine receptors

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 39, Issue 10, 1997, Pages 827-832

  Ding, Y S ^a   Liang, F ^b   Fowler, J S ^a   Kuhar, M J ^c   Carroll, F I ^b  

^a BROOKHAVEN NATIONAL LABORATORY   (United States)

^b RTI INTERNATIONAL   (United States)

^c NIDA Addiction Research Center   (United States)

Author keywords

Epibatidine; Fluorine 18; Nicotinic acetylcholine receptors; Positron emission tomography

Indexed keywords

ALKYLATION; CHELATION; FLUORINE; FLUORINE COMPOUNDS; LIGANDS; SODIUM COMPOUNDS;

ACETYLCHOLINE RECEPTOR; DEPROTECTION; EPIBATIDINE; FLUORINE-18; METHYL DERIVATIVES; N-METHYLATION; NICOTINIC ACETYLCHOLINE; NICOTINIC ACETYLCHOLINE RECEPTOR; RADIOCHEMICAL YIELD; SYNTHESIS TIME;

POSITRON EMISSION TOMOGRAPHY;

EPIBATIDINE; FLUORINE 18; LIGAND; NICOTINIC RECEPTOR;

ARTICLE; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POSITRON EMISSION TOMOGRAPHY; REACTION ANALYSIS;

EID: 0030821834     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199710)39:10<827::AID-JLCR29>3.0.CO;2-7     Document Type: Article

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